The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
Abbott Laboratories Common 002824100 47,206 431,145 SH   SOLE   431,145 0 0
AbbVie Inc. Common 00287Y109 66,407 619,759 SH   SOLE   619,759 0 0
ABIOMED, Inc. Common 003654100 3,505 10,812 SH   SOLE   10,812 0 0
AC Immune SA Shares H00263105 888 171,813 SH   SOLE   171,813 0 0
ACADIA Pharmaceuticals Inc. Common 004225108 17,737 331,789 SH   SOLE   331,789 0 0
Adaptive Biotechnologies Corporation Common 00650F109 16,912 286,013 SH   SOLE   286,013 0 0
Addus HomeCare Corporation Common 006739106 4,407 37,640 SH   SOLE   37,640 0 0
Aerie Pharmaceuticals, Inc. Common 00771V108 901 66,688 SH   SOLE   66,688 0 0
Affimed N.V. Common N01045108 1,560 268,019 SH   SOLE   268,019 0 0
Agilent Technologies, Inc. Common 00846U101 6,224 52,525 SH   SOLE   52,525 0 0
Alcon Inc. Ordinary Shares H01301128 2,064 31,286 SH   SOLE   31,286 0 0
Alexion Pharmaceuticals, Inc. Common 015351109 78,423 501,942 SH   SOLE   501,942 0 0
Align Technology, Inc. Common 016255101 5,366 10,041 SH   SOLE   10,041 0 0
Alkermes plc Shares G01767105 3,390 169,930 SH   SOLE   169,930 0 0
Allakos Inc. Common 01671P100 18,331 130,937 SH   SOLE   130,937 0 0
Allogene Therapeutics, Inc. Common 019770106 1,214 48,089 SH   SOLE   48,089 0 0
Alnylam Pharmaceuticals, Inc. Common 02043Q107 22,731 174,894 SH   SOLE   174,894 0 0
Amarin Corporation PLC Sponsored ADR 023111206 4,154 849,588 SH   SOLE   849,588 0 0
Amedisys, Inc. Common 023436108 5,689 19,395 SH   SOLE   19,395 0 0
Amgen Inc. Common 031162100 95,775 416,560 SH   SOLE   416,560 0 0
Amicus Therapeutics, Inc. Common 03152W109 9,366 405,626 SH   SOLE   405,626 0 0
Anthem, Inc. Common 036752103 11,923 37,133 SH   SOLE   37,133 0 0
Apellis Pharmaceuticals, Inc. Common 03753U106 12,356 216,017 SH   SOLE   216,017 0 0
ARCA biopharma, Inc. Common 00211Y506 130 32,461 SH   SOLE   32,461 0 0
Ardelyx, Inc. Common 039697107 3,932 607,698 SH   SOLE   607,698 0 0
Arena Pharmaceuticals, Inc. Common 040047607 19,436 252,971 SH   SOLE   252,971 0 0
Argenx SE Sponsored ADR 04016X101 18,142 61,687 SH   SOLE   61,687 0 0
Arrowhead Pharmaceuticals, Inc. Common 04280A100 10,196 132,886 SH   SOLE   132,886 0 0
Arvinas, Inc. Common 04335A105 6,239 73,459 SH   SOLE   73,459 0 0
Ascendis Pharma A/S Sponsored ADR 04351P101 16,052 96,246 SH   SOLE   96,246 0 0
Assertio Holdings, Inc. Common 04546C106 587 1,642,302 SH   SOLE   1,642,302 0 0
AstraZeneca PLC Sponsored ADR 046353108 17,213 344,333 SH   SOLE   344,333 0 0
Atreca, Inc. Class A Common 04965G109 5,692 352,424 SH   SOLE   352,424 0 0
Aurinia Pharmaceuticals Inc. Common 05156V102 4,157 300,611 SH   SOLE   300,611 0 0
Avadel Pharmaceuticals plc Sponsored ADR 05337M104 1,561 233,612 SH   SOLE   233,612 0 0
Axonics Modulation Technologies, Inc. Common 05465P101 4,032 80,760 SH   SOLE   80,760 0 0
Axsome Therapeutics, Inc. Common 05464T104 2,574 31,591 SH   SOLE   31,591 0 0
Bausch Health Companies Inc. Common 071734107 2,109 101,412 SH   SOLE   101,412 0 0
Becton, Dickinson and Company Common 075887109 32,960 131,723 SH   SOLE   131,723 0 0
BeiGene, Ltd. Sponsored ADR 07725L102 7,307 28,280 SH   SOLE   28,280 0 0
Bellicum Pharmaceuticals, Inc. Common 079481404 21 6,000 SH   SOLE   6,000 0 0
Bio-Techne Corporation Common 09073M104 16,421 51,710 SH   SOLE   51,710 0 0
Biogen Inc. Common 09062X103 60,442 246,844 SH   SOLE   246,844 0 0
BioMarin Pharmaceutical Inc. Common 09061G101 24,407 278,330 SH   SOLE   278,330 0 0
Blueprint Medicines Corporation Common 09627Y109 13,761 122,699 SH   SOLE   122,699 0 0
Boston Scientific Corporation Common 101137107 8,847 246,089 SH   SOLE   246,089 0 0
Bristol Myers Squibb Company Common 110122108 61,404 989,908 SH   SOLE   989,908 0 0
Bristol Myers Squibb Company Right 110122157 1,017 1,473,710 SH   SOLE   1,473,710 0 0
Celldex Therapeutics, Inc. Common 15117B202 124 7,053 SH   SOLE   7,053 0 0
Cellectis Sponsored ADR 15117K103 324 11,955 SH   SOLE   11,955 0 0
Centene Corporation Common 15135B101 5,051 84,145 SH   SOLE   84,145 0 0
Charles River Laboratories International, Inc. Common 159864107 7,035 28,154 SH   SOLE   28,154 0 0
ChemoCentryx, Inc. Common 16383L106 8,944 144,447 SH   SOLE   144,447 0 0
Cigna Corporation Common 125523100 28,253 135,712 SH   SOLE   135,712 0 0
Clearside Biomedical, Inc. Common 185063104 453 165,330 SH   SOLE   165,330 0 0
Cogent Biosciences, Inc. Common 19240Q201 6,039 537,742 SH   SOLE   537,742 0 0
Community Health Systems, Inc. Common 203668108 875 117,735 SH   SOLE   117,735 0 0
Community Healthcare Trust Incorporated Common 20369C106 702 14,900 SH   SOLE   14,900 0 0
Corbus Pharmaceuticals Holdings, Inc. Common 21833P103 517 413,481 SH   SOLE   413,481 0 0
CRISPR Therapeutics AG Namen AKT H17182108 11,670 76,222 SH   SOLE   76,222 0 0
CVS Health Corporation Common 126650100 15,026 219,995 SH   SOLE   219,995 0 0
CymaBay Therapeutics, Inc. Common 23257D103 506 88,102 SH   SOLE   88,102 0 0
Danaher Corporation Common 235851102 48,835 219,840 SH   SOLE   219,840 0 0
Deciphera Pharmaceuticals, Inc. Common 24344T101 3,502 61,370 SH   SOLE   61,370 0 0
Denali Therapeutics Inc. Common 24823R105 6,059 72,333 SH   SOLE   72,333 0 0
DENTSPLY SIRONA Inc. Common 24906P109 19,160 365,927 SH   SOLE   365,927 0 0
DexCom, Inc. Common 252131107 27,597 74,643 SH   SOLE   74,643 0 0
Dicerna Pharmaceuticals, Inc. Common 253031108 1,501 68,150 SH   SOLE   68,150 0 0
Diversified Healthcare Trust Common 25525P107 1,474 357,720 SH   SOLE   357,720 0 0
Edwards Lifesciences Corporation Common 28176E108 24,172 264,955 SH   SOLE   264,955 0 0
Eidos Therapeutics, Inc. Common 28249H104 2,632 20,000 SH   SOLE   20,000 0 0
Eli Lilly and Company Common 532457108 40,106 237,537 SH   SOLE   237,537 0 0
Endo International plc Shares G30401106 3,817 531,570 SH   SOLE   531,570 0 0
Esperion Therapeutics, Inc. Common 29664W105 1,081 41,577 SH   SOLE   41,577 0 0
Exact Sciences Corporation Common 30063P105 8,413 63,502 SH   SOLE   63,502 0 0
Exelixis, Inc. Common 30161Q104 25,218 1,256,520 SH   SOLE   1,256,520 0 0
Fate Therapeutics, Inc. Common 31189P102 15,123 166,317 SH   SOLE   166,317 0 0
FibroGen, Inc. Common 31572Q808 7,205 194,270 SH   SOLE   194,270 0 0
Five Star Senior Living Inc. Common 33832D205 167 24,237 SH   SOLE   24,237 0 0
Forma Therapeutics Holdings, Inc. Shares 34633R104 5,229 149,825 SH   SOLE   149,825 0 0
Galera Therapeutics, Inc. Common 36338D108 10,658 1,041,845 SH   SOLE   1,041,845 0 0
Genmab A/S Sponsored ADS 372303206 10,518 258,672 SH   SOLE   258,672 0 0
Gilead Sciences, Inc. Common 375558103 81,877 1,405,371 SH   SOLE   1,405,371 0 0
Global Medical REIT Inc. Common 37954A204 2,284 174,897 SH   SOLE   174,897 0 0
Grifols, S.A. Sponsored ADR 398438408 874 47,373 SH   SOLE   47,373 0 0
Gritstone Oncology, Inc. Common 39868T105 1,651 419,005 SH   SOLE   419,005 0 0
Guardant Health, Inc. Common 40131M109 15,189 117,852 SH   SOLE   117,852 0 0
Harpoon Therapeutics, Inc. Common 41358P106 1,768 106,419 SH   SOLE   106,419 0 0
HCA Healthcare, Inc. Common 40412C101 28,796 175,097 SH   SOLE   175,097 0 0
Health Care Select Sector SPDR Fund SBI Healthcare 81369Y209 1,141 10,055 SH   SOLE   10,055 0 0
Healthcare Realty Trust Incorporated Common 421946104 3,079 104,024 SH   SOLE   104,024 0 0
Healthcare Trust of America, Inc. Common 42225P501 1,946 70,662 SH   SOLE   70,662 0 0
Healthpeak Properties, Inc. Common 42250P103 4,546 150,392 SH   SOLE   150,392 0 0
Helix Acquisition Corp. Class A Common G4444C102 2,708 250,000 SH   SOLE   250,000 0 0
Heron Therapeutics, Inc. Common 427746102 2,776 131,183 SH   SOLE   131,183 0 0
Hologic, Inc. Common 436440101 2,372 32,564 SH   SOLE   32,564 0 0
Horizon Therapeutics plc Shares G46188101 34,016 465,016 SH   SOLE   465,016 0 0
Humana Inc. Common 444859102 33,973 82,807 SH   SOLE   82,807 0 0
IDEXX Laboratories, Inc. Common 45168D104 17,402 34,814 SH   SOLE   34,814 0 0
Illumina, Inc. Common 452327109 95,272 257,493 SH   SOLE   257,493 0 0
ImmunoGen, Inc. Common 45253H101 1,085 168,190 SH   SOLE   168,190 0 0
Incyte Corporation Common 45337C102 8,111 93,257 SH   SOLE   93,257 0 0
Inogen, Inc. Common 45780L104 2,297 51,406 SH   SOLE   51,406 0 0
Insmed Incorporated Common 457669307 3,275 98,387 SH   SOLE   98,387 0 0
Intercept Pharmaceuticals, Inc. Common 45845P108 1,904 77,067 SH   SOLE   77,067 0 0
Intra-Cellular Therapies, Inc. Common 46116X101 11,644 366,176 SH   SOLE   366,176 0 0
Intuitive Surgical, Inc. Common 46120E602 17,422 21,296 SH   SOLE   21,296 0 0
Ionis Pharmaceuticals, Inc. Common 462222100 10,924 193,201 SH   SOLE   193,201 0 0
Iovance Biotherapeutics, Inc. Common 462260100 12,578 271,073 SH   SOLE   271,073 0 0
IQVIA Holdings Inc. Common 46266C105 13,629 76,066 SH   SOLE   76,066 0 0
Jazz Pharmaceuticals plc Shares G50871105 11,134 67,456 SH   SOLE   67,456 0 0
Johnson & Johnson Common 478160104 86,056 546,805 SH   SOLE   546,805 0 0
Kadmon Holdings, Inc. Common 48283N106 2,963 714,008 SH   SOLE   714,008 0 0
Karuna Therapeutics, Inc. Common 48576A100 8,659 85,236 SH   SOLE   85,236 0 0
Karyopharm Therapeutics Inc. Common 48576U106 1,018 65,743 SH   SOLE   65,743 0 0
Koninklijke Philips N.V. NY Reg Sh 500472303 3,084 56,927 SH   SOLE   56,927 0 0
Kura Oncology, Inc. Common 50127T109 8,931 273,463 SH   SOLE   273,463 0 0
Laboratory Corporation of America Holdings Sponsored ADR 50540R409 13,150 64,603 SH   SOLE   64,603 0 0
LTC Properties, Inc. Common 502175102 7,093 182,293 SH   SOLE   182,293 0 0
Madrigal Pharmaceuticals, Inc. Common 558868105 1,483 13,340 SH   SOLE   13,340 0 0
Magenta Therapeutics, Inc. Common 55910K108 1,509 192,431 SH   SOLE   192,431 0 0
McKesson Corp. Common 58155Q103 22,688 130,448 SH   SOLE   130,448 0 0
Medical Properties Trust, Inc. Common 58463J304 8,972 411,743 SH   SOLE   411,743 0 0
Medpace Holdings, Inc. Common 58506Q109 2,627 18,871 SH   SOLE   18,871 0 0
Medtronic plc Shares G5960L103 62,660 534,914 SH   SOLE   534,914 0 0
Merck & Co., Inc. Common 58933Y105 45,882 560,903 SH   SOLE   560,903 0 0
Mettler-Toledo International Inc. Common 592688105 11,169 9,800 SH   SOLE   9,800 0 0
Milestone Pharmaceuticals Inc. Common 59935V107 1,699 253,610 SH   SOLE   253,610 0 0
Mirati Therapeutics, Inc. Common 60468T105 18,402 83,784 SH   SOLE   83,784 0 0
Moderna, Inc. Common 60770K107 25,929 248,192 SH   SOLE   248,192 0 0
Molecular Templates, Inc. Common 608550109 2,064 219,822 SH   SOLE   219,822 0 0
Molina Healthcare, Inc. Common 60855R100 8,458 39,769 SH   SOLE   39,769 0 0
MorphoSys AG Sponsored ADS 617760202 2,320 81,867 SH   SOLE   81,867 0 0
National Health Investors, Inc. Common 63633D104 694 10,038 SH   SOLE   10,038 0 0
Nektar Therapeutics Common 640268108 3,067 180,438 SH   SOLE   180,438 0 0
Neurocrine Biosciences, Inc. Common 64125C109 28,202 294,234 SH   SOLE   294,234 0 0
New Senior Investment Group Inc. Common 648691103 1,328 256,398 SH   SOLE   256,398 0 0
Novartis AG Sponsored ADR 66987V109 13,647 144,525 SH   SOLE   144,525 0 0
Novavax, Inc. Common 670002401 8,540 76,585 SH   SOLE   76,585 0 0
Novo Nordisk A/S Sponsored ADR 670100205 4,534 64,906 SH   SOLE   64,906 0 0
NovoCure Limited Ordinary Shares G6674U108 15,213 87,918 SH   SOLE   87,918 0 0
NuCana plc Sponsored ADR 67022C106 2,068 460,672 SH   SOLE   460,672 0 0
Omega Healthcare Investors, Inc. Common 681936100 11,130 306,433 SH   SOLE   306,433 0 0
Ovid Therapeutics Inc. Sponsored ADR 690469101 861 372,733 SH   SOLE   372,733 0 0
Owens & Minor, Inc. Common 690732102 7,196 266,023 SH   SOLE   266,023 0 0
PerkinElmer, Inc. Common 714046109 5,323 37,094 SH   SOLE   37,094 0 0
Perrigo Company plc Shares G97822103 2,291 51,224 SH   SOLE   51,224 0 0
Pfizer Inc. Common 717081103 25,961 705,259 SH   SOLE   705,259 0 0
Physicians Realty Trust Common 71943U104 8,824 495,733 SH   SOLE   495,733 0 0
Pieris Pharmaceuticals, Inc. Common 720795103 3,623 1,449,269 SH   SOLE   1,449,269 0 0
PRA Health Sciences, Inc. Common 69354M108 22,057 175,838 SH   SOLE   175,838 0 0
Praxis Precision Medicines, Inc. Common 74006W108 4,127 75,000 SH   SOLE   75,000 0 0
Quest Diagnostics Incorporated Common 74834L100 13,068 109,659 SH   SOLE   109,659 0 0
Reata Pharmaceuticals, Inc. Class A 75615P103 4,725 38,219 SH   SOLE   38,219 0 0
Regeneron Pharmaceuticals, Inc. Common 75886F107 86,663 179,385 SH   SOLE   179,385 0 0
REGENXBIO Inc. Common 75901B107 984 21,700 SH   SOLE   21,700 0 0
ResMed Inc. Common 761152107 28,131 132,344 SH   SOLE   132,344 0 0
Revance Therapeutics, Inc. Common 761330109 6,059 213,808 SH   SOLE   213,808 0 0
Sabra Health Care REIT, Inc. Common 78573L106 8,870 510,660 SH   SOLE   510,660 0 0
Sage Therapeutics, Inc. Common 78667J108 13,153 152,040 SH   SOLE   152,040 0 0
Sanofi Sponsored ADR 80105N105 3,963 81,554 SH   SOLE   81,554 0 0
Sarepta Therapeutics, Inc. Common 803607100 35,204 206,487 SH   SOLE   206,487 0 0
Scholar Rock Holding Corporation Common 80706P103 5,634 116,094 SH   SOLE   116,094 0 0
Seagen Inc. Common 81181C104 51,424 293,619 SH   SOLE   293,619 0 0
Smith & Nephew plc Shares 83175M205 4,198 99,560 SH   SOLE   99,560 0 0
Spectrum Pharmaceuticals, Inc. Common 84763A108 391 114,670 SH   SOLE   114,670 0 0
STERIS plc Shares G8473T100 24,030 126,779 SH   SOLE   126,779 0 0
Stryker Corporation Common 863667101 37,572 153,330 SH   SOLE   153,330 0 0
Sutro Biopharma, Inc. Common 869367102 15,252 702,523 SH   SOLE   702,523 0 0
Syneos Health, Inc. Class A 87166B102 13,295 195,136 SH   SOLE   195,136 0 0
Takeda Pharmaceutical Company Limited Sponsored ADS 874060205 3,825 210,146 SH   SOLE   210,146 0 0
Teladoc Health, Inc. Common 87918A105 11,302 56,520 SH   SOLE   56,520 0 0
Teleflex Incorporated Common 879369106 6,195 15,052 SH   SOLE   15,052 0 0
Tenet Healthcare Corporation Common 88033G407 3,304 82,736 SH   SOLE   82,736 0 0
Tetraphase Pharmaceuticals, Inc. Common 881CVR013 9 42,965 SH   SOLE   42,965 0 0
Teva Pharmaceutical Industries Ltd. Sponsored ADR 881624209 7,045 730,051 SH   SOLE   730,051 0 0
TG Therapeutics, Inc. Common 88322Q108 6,933 133,269 SH   SOLE   133,269 0 0
Theravance Biopharma, Inc. Common G8807B106 8,108 456,296 SH   SOLE   456,296 0 0
Thermo Fisher Scientific Inc. Common 883556102 59,412 127,553 SH   SOLE   127,553 0 0
Trillium Therapeutics Inc. Common 89620X506 12,030 817,784 SH   SOLE   817,784 0 0
Turning Point Therapeutics, Inc. Common 90041T108 14,540 119,324 SH   SOLE   119,324 0 0
Ultragenyx Pharmaceutical Inc. Common 90400D108 13,494 97,480 SH   SOLE   97,480 0 0
uniQure N.V. Shares N90064101 4,516 125,003 SH   SOLE   125,003 0 0
United Therapeutics Corporation Class B 91307C102 9,641 63,513 SH   SOLE   63,513 0 0
Unitedhealth Group Incorporated Common 91324P102 76,864 219,185 SH   SOLE   219,185 0 0
Universal Health Realty Income Trust Shares 91359E105 724 11,258 SH   SOLE   11,258 0 0
Ventas, Inc. Common 92276F100 10,206 208,108 SH   SOLE   208,108 0 0
Verona Pharma plc Sponsored ADR 925050106 5,263 751,905 SH   SOLE   751,905 0 0
Vertex Pharmaceuticals Incorporated Common 92532F100 72,157 305,310 SH   SOLE   305,310 0 0
Viatris Inc. Common 92556V106 251 13,400 SH   SOLE   13,400 0 0
VYNE Therapeutics Inc. Common 92941V100 856 541,584 SH   SOLE   541,584 0 0
Waters Corporation Common 941848103 27,095 109,510 SH   SOLE   109,510 0 0
Welltower Inc. Common 95040Q104 13,123 203,083 SH   SOLE   203,083 0 0
Xencor, Inc. Common 98401F105 6,467 148,231 SH   SOLE   148,231 0 0
Y-mAbs Therapeutics, Inc. Common 984241109 3,790 76,548 SH   SOLE   76,548 0 0
Zai Lab Limited ADR 98887Q104 5,078 37,523 SH   SOLE   37,523 0 0
Zimmer Biomet Holdings, Inc. Common 98956P102 32,977 214,014 SH   SOLE   214,014 0 0
Zoetis Inc. Class A 98978V103 9,354 56,521 SH   SOLE   56,521 0 0
Zogenix, Inc. Common 98978L204 1,779 88,977 SH   SOLE   88,977 0 0
Zymeworks Inc. Common 98985W102 2,644 55,938 SH   SOLE   55,938 0 0