The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
10X GENOMICS INC CL A COM 88025U109 10,762 76,000 SH   SOLE   76,000 0 0
ABCAM PLC ADS 000380204 19,934 925,000 SH   SOLE   925,000 0 0
ACADIA HEALTHCARE COMPANY IN COM 00404A109 35,182 700,000 SH   SOLE   700,000 0 0
ACADIA PHARMACEUTICALS INC COM 004225108 86,204 1,612,500 SH   SOLE   1,612,500 0 0
ACCOLADE INC COM 00437E102 21,750 500,000 SH   SOLE   500,000 0 0
ACELRX PHARMACEUTICALS INC COM 00444T100 4,690 3,782,457 SH   SOLE   3,782,457 0 0
ACLARIS THERAPEUTICS INC COM 00461U105 17,314 2,676,100 SH   SOLE   2,676,100 0 0
ADAPTIMMUNE THERAPEUTICS PLC SPONDS ADR 00653A107 8,328 1,545,000 SH   SOLE   1,545,000 0 0
ADAPTIVE BIOTECHNOLOGIES COR COM 00650F109 37,548 635,000 SH   SOLE   635,000 0 0
AEGLEA BIOTHERAPEUTICS INC COM 00773J103 12,435 1,580,000 SH   SOLE   1,580,000 0 0
AGIOS PHARMACEUTICALS INC COM 00847X104 109,344 2,523,521 SH   SOLE   2,523,521 0 0
AKERO THERAPEUTICS INC COM 00973Y108 13,297 515,371 SH   SOLE   515,371 0 0
ALEXION PHARMACEUTICALS INC COM 015351109 47,927 306,750 SH   SOLE   306,750 0 0
ALIGN TECHNOLOGY INC COM 016255101 87,371 163,500 SH   SOLE   163,500 0 0
ALLAKOS INC COM 01671P100 47,810 341,500 SH   SOLE   341,500 0 0
ALNYLAM PHARMACEUTICALS INC COM 02043Q107 43,540 335,000 SH   SOLE   335,000 0 0
AMARIN CORP PLC SPONS ADR NEW 023111206 20,514 4,195,000 SH   SOLE   4,195,000 0 0
AMICUS THERAPEUTICS INC COM 03152W109 23,760 1,029,000 SH   SOLE   1,029,000 0 0
ANAPTYSBIO INC COM 032724106 6,652 309,413 SH   SOLE   309,413 0 0
ANNEXON INC COM 03589W102 1,137 45,413 SH   SOLE   45,413 0 0
APPLIED THERAPEUTICS INC COM 03828A101 13,995 635,837 SH   SOLE   635,837 0 0
ARDELYX INC COM 039697107 33,308 5,148,112 SH   SOLE   5,148,112 0 0
ARGENX SE SPONSORED ADR 04016X101 84,551 287,500 SH   SOLE   287,500 0 0
ARVINAS INC COM 04335A105 63,358 746,000 SH   SOLE   746,000 0 0
ASCENDIS PHARMA A/S SPONSORED ADR 04351P101 38,943 233,500 SH   SOLE   233,500 0 0
ATEA PHARMACEUTICALS INC COM 04683R106 70,917 1,697,403 SH   SOLE   1,697,403 0 0
ATHIRA PHARMA INC COM 04746L104 29,486 860,902 SH   SOLE   860,902 0 0
ATRECA INC CL A COM 04965G109 7,287 451,230 SH   SOLE   451,230 0 0
AURINIA PHARMACEUTICALS INC COM 05156V102 10,700 773,669 SH   SOLE   773,669 0 0
BAXTER INTL INC COM 071813109 24,152 301,000 SH   SOLE   301,000 0 0
BCLS ACQUISITION CORP COM CL A G0904B105 3,442 309,000 SH   SOLE   309,000 0 0
BEIGENE LTD SPONSORED ADR 07725L102 58,138 225,000 SH   SOLE   225,000 0 0
BIOGEN INC COM 09062X103 24,486 100,000 SH   SOLE   100,000 0 0
BIOGEN INC COM 09062X103 31,832 130,000 SH Call SOLE   130,000 0 0
BIOMARIN PHARMACEUTICAL INC COM 09061G101 22,229 253,500 SH   SOLE   253,500 0 0
BLUEPRINT MEDICINES CORP COM 09627Y109 94,430 842,000 SH   SOLE   842,000 0 0
BOSTON SCIENTIFIC CORP COM 101137107 28,760 800,000 SH   SOLE   800,000 0 0
BRIGHT HORIZONS FAM SOL IN D COM 109194100 28,630 165,500 SH   SOLE   165,500 0 0
CENTENE CORP DEL COM 15135B101 43,822 730,000 SH   SOLE   730,000 0 0
CEREVEL THERAPEUTICS HLDNG I COM 15678U128 16,563 999,000 SH   SOLE   999,000 0 0
CERTARA INC COM 15687V109 5,058 150,000 SH   SOLE   150,000 0 0
CHIASMA INC COM 16706W102 9,294 2,136,514 SH   SOLE   2,136,514 0 0
CHINOOK THERAPEUTICS INC COM 16961L106 10,608 668,849 SH   SOLE   668,849 0 0
COHERUS BIOSCIENCES INC COM 19249H103 20,204 1,162,500 SH   SOLE   1,162,500 0 0
COLLEGIUM PHARMACEUTICAL INC COM 19459J104 22,033 1,100,000 SH   SOLE   1,100,000 0 0
COMPUGEN LTD ORD M25722105 13,728 1,133,600 SH   SOLE   1,133,600 0 0
CONMED CORP COM 207410101 8,736 78,000 SH   SOLE   78,000 0 0
CONSTELLATION PHARMCETICLS I COM 210373106 6,703 232,743 SH   SOLE   232,743 0 0
COVETRUS INC COM 22304C100 36,931 1,285,000 SH   SOLE   1,285,000 0 0
CYTOKINETICS INC NOTE 4.000%11/1 23282WAA8 17,270 8,000,000 PRN   SOLE   8,000,000 0 0
DYNAVAX TECHNOLOGIES CORP COM NEW 268158201 7,340 1,649,420 SH   SOLE   1,649,420 0 0
EARGO INC COM 270087109 40,338 900,000 SH   SOLE   900,000 0 0
EDWARDS LIFESCIENCES CORP COM 28176E108 53,096 582,000 SH   SOLE   582,000 0 0
ENCOMPASS HEALTH CORP COM 29261A100 41,345 500,000 SH   SOLE   500,000 0 0
EPIZYME INC COM 29428V104 27,728 2,553,208 SH   SOLE   2,553,208 0 0
EUCRATES BIOMEDICAL ACQU COR UNIT 10/23/2027 G3141W114 2,196 206,000 SH   SOLE   206,000 0 0
EXACT SCIENCES CORP COM 30063P105 64,258 485,000 SH   SOLE   485,000 0 0
FIBROGEN INC COM 31572Q808 11,475 309,387 SH   SOLE   309,387 0 0
FIVE PRIME THERAPEUTICS INC COM 33830X104 12,275 721,633 SH   SOLE   721,633 0 0
FRESHPET INC COM 358039105 71,918 506,500 SH   SOLE   506,500 0 0
FUSION PHARMACEUTICALS INC COM 36118A100 11,143 948,327 SH   SOLE   948,327 0 0
GALAPAGOS NV SPON ADR 36315X101 16,332 165,000 SH   SOLE   165,000 0 0
GALERA THERAPEUTICS INC COM 36338D108 5,806 567,552 SH   SOLE   567,552 0 0
GAMIDA CELL LTD SHS M47364100 17,569 2,094,000 SH   SOLE   2,094,000 0 0
GLOBAL CORD BLOOD CORPORATIO SHS G39342103 2,875 775,000 SH   SOLE   775,000 0 0
GOSSAMER BIO INC NOTE 5.000% 6/0 38341PAA0 14,184 15,573,000 PRN   SOLE   15,573,000 0 0
GUARDANT HEALTH INC COM 40131M109 25,776 200,000 SH   SOLE   200,000 0 0
GW PHARMACEUTICALS PLC ADS 36197T103 13,755 119,188 SH   SOLE   119,188 0 0
HCA HEALTHCARE INC COM 40412C101 74,007 450,000 SH   SOLE   450,000 0 0
HEALTH CATALYST INC COM 42225T107 34,171 785,000 SH   SOLE   785,000 0 0
HEALTHEQUITY INC COM 42226A107 5,228 75,000 SH   SOLE   75,000 0 0
HELIX ACQUISITION CORP COM CL A G4444C102 1,757 154,500 SH   SOLE   154,500 0 0
HORIZON THERAPEUTICS PUB L SHS G46188101 45,719 625,000 SH   SOLE   625,000 0 0
HUMANA INC COM 444859102 116,927 285,000 SH   SOLE   285,000 0 0
IDEXX LABS INC COM 45168D104 62,484 125,000 SH   SOLE   125,000 0 0
IMARA INC COM 45249V107 7,949 360,500 SH   SOLE   360,500 0 0
IMMUNOVANT INC COM 45258J102 41,155 891,000 SH   SOLE   891,000 0 0
INCYTE CORP COM 45337C102 26,094 300,000 SH   SOLE   300,000 0 0
INOZYME PHARMA INC COM 45790W108 17,142 830,546 SH   SOLE   830,546 0 0
INSMED INC NOTE 1.750% 1/1 457669AA7 6,763 6,000,000 PRN   SOLE   6,000,000 0 0
INSPIRE MED SYS INC COM 457730109 40,129 213,350 SH   SOLE   213,350 0 0
INSULET CORP COM 45784P101 81,290 318,000 SH   SOLE   318,000 0 0
INTERSECT ENT INC COM 46071F103 16,030 700,000 SH   SOLE   700,000 0 0
INTUITIVE SURGICAL INC COM NEW 46120E602 98,172 120,000 SH   SOLE   120,000 0 0
INVITAE CORP COM 46185L103 77,435 1,852,067 SH   SOLE   1,852,067 0 0
IRHYTHM TECHNOLOGIES INC COM 450056106 148,256 625,000 SH   SOLE   625,000 0 0
ITEOS THERAPEUTICS INC COM 46565G104 5,410 159,957 SH   SOLE   159,957 0 0
JAZZ PHARMACEUTICALS PLC SHS USD G50871105 14,442 87,500 SH   SOLE   87,500 0 0
JIYA ACQUISITION CORP COM CL A 47760M102 2,124 206,200 SH   SOLE   206,200 0 0
KARUNA THERAPEUTICS INC COM 48576A100 24,783 243,950 SH   SOLE   243,950 0 0
KINNATE BIOPHARMA INC COM 49705R105 12,916 324,686 SH   SOLE   324,686 0 0
KURA ONCOLOGY INC COM 50127T109 16,595 508,116 SH   SOLE   508,116 0 0
KYMERA THERAPEUTICS INC COM 501575104 44,260 713,865 SH   SOLE   713,865 0 0
LEGEND BIOTECH CORP SPONSORED ADS 52490G102 8,713 309,418 SH   SOLE   309,418 0 0
LIFESCI ACQUISITION II CORP COM 53229E103 2,200 206,200 SH   SOLE   206,200 0 0
MACROGENICS INC COM 556099109 7,075 309,510 SH   SOLE   309,510 0 0
MADRIGAL PHARMACEUTICALS INC COM 558868105 28,545 256,768 SH   SOLE   256,768 0 0
MERSANA THERAPEUTICS INC COM 59045L106 54,914 2,063,667 SH   SOLE   2,063,667 0 0
MIRATI THERAPEUTICS INC COM 60468T105 81,959 373,152 SH   SOLE   373,152 0 0
MIRUM PHARMACEUTICALS INC COM 604749101 26,129 1,496,525 SH   SOLE   1,496,525 0 0
MYOVANT SCIENCES LTD COM G637AM102 14,224 515,000 SH   SOLE   515,000 0 0
NEUROCRINE BIOSCIENCES INC COM 64125C109 150,964 1,575,000 SH   SOLE   1,575,000 0 0
NEUROCRINE BIOSCIENCES INC NOTE 2.250% 5/1 64125CAD1 1,390 1,000,000 PRN   SOLE   1,000,000 0 0
NEVRO CORP COM 64157F103 68,375 395,000 SH   SOLE   395,000 0 0
NEVRO CORP NOTE 2.750% 4/0 64157FAC7 912 500,000 PRN   SOLE   500,000 0 0
NGM BIOPHARMACEUTICALS INC COM 62921N105 10,921 360,500 SH   SOLE   360,500 0 0
NKARTA INC COM 65487U108 33,255 541,000 SH   SOLE   541,000 0 0
NOVAVAX INC COM NEW 670002401 62,803 563,205 SH   SOLE   563,205 0 0
NOVOCURE LTD ORD SHS G6674U108 30,282 175,000 SH   SOLE   175,000 0 0
NURIX THERAPEUTICS INC COM 67080M103 8,458 257,250 SH   SOLE   257,250 0 0
OAK STR HEALTH INC COM 67181A107 22,935 375,000 SH   SOLE   375,000 0 0
ODONATE THERAPEUTICS INC COM 676079106 7,252 377,700 SH   SOLE   377,700 0 0
ONESPAWORLD HOLDINGS LIMITED COM P73684113 6,997 690,000 SH   SOLE   690,000 0 0
PACIRA BIOSCIENCES INC COM 695127100 61,336 1,025,000 SH   SOLE   1,025,000 0 0
PACIRA BIOSCIENCES INC NOTE 2.375% 4/0 695127AD2 1,149 1,000,000 PRN   SOLE   1,000,000 0 0
PANACEA ACQUISITION CORP UNIT 99/99/9999 698102209 5,131 402,088 SH   SOLE   402,088 0 0
PARATEK PHARMACEUTICALS INC COM 699374302 10,521 1,680,614 SH   SOLE   1,680,614 0 0
PENUMBRA INC COM 70975L107 27,825 159,000 SH   SOLE   159,000 0 0
PHASEBIO PHARMACEUTICALS INC COM 717224109 4,416 1,314,374 SH   SOLE   1,314,374 0 0
PHREESIA INC COM 71944F106 46,121 850,000 SH   SOLE   850,000 0 0
POPULATION HEALTH INVS CO IN UNIT 99/99/9999 G71716123 2,101 201,044 SH   SOLE   201,044 0 0
POSEIDA THERAPEUTICS INC COM 73730P108 3,179 289,754 SH   SOLE   289,754 0 0
PPD INC COM 69355F102 17,966 525,000 SH   SOLE   525,000 0 0
PRELUDE THERAPEUTICS INC COM 74065P101 25,784 360,363 SH   SOLE   360,363 0 0
PROTARA THERAPEUTICS INC COM STK 74365U107 15,572 643,200 SH   SOLE   643,200 0 0
PROTHENA CORP PLC SHS G72800108 13,705 1,141,100 SH   SOLE   1,141,100 0 0
PULMONX CORP COM 745848101 34,510 500,000 SH   SOLE   500,000 0 0
RADIUS HEALTH INC NOTE 3.000% 9/0 750469AA6 1,348 1,500,000 PRN   SOLE   1,500,000 0 0
RELAY THERAPEUTICS INC COM 75943R102 17,123 412,000 SH   SOLE   412,000 0 0
RETROPHIN INC NOTE 2.500% 9/1 761299AB2 3,311 3,250,000 PRN   SOLE   3,250,000 0 0
RHYTHM PHARMACEUTICALS INC COM 76243J105 14,578 490,339 SH   SOLE   490,339 0 0
RIGEL PHARMACEUTICALS INC COM NEW 766559603 16,600 4,742,891 SH   SOLE   4,742,891 0 0
ROCKET PHARMACEUTICALS INC COM 77313F106 21,956 400,370 SH   SOLE   400,370 0 0
ROYALTY PHARMA PLC SHS CLASS A G7709Q104 24,024 480,000 SH   SOLE   480,000 0 0
SAREPTA THERAPEUTICS INC COM 803607100 56,049 328,750 SH   SOLE   328,750 0 0
SEAGEN INC COM 81181C104 43,785 250,000 SH   SOLE   250,000 0 0
SHATTUCK LABS INC COM 82024L103 25,628 489,000 SH   SOLE   489,000 0 0
SHOCKWAVE MED INC COM 82489T104 22,818 220,000 SH   SOLE   220,000 0 0
SIERRA ONCOLOGY INC COM NEW 82640U404 9,095 567,358 SH   SOLE   567,358 0 0
SPERO THERAPEUTICS INC COM 84833T103 23,947 1,235,000 SH   SOLE   1,235,000 0 0
SPRUCE BIOSCIENCES INC COM 85209E109 39,650 1,631,000 SH   SOLE   1,631,000 0 0
TELEFLEX INCORPORATED COM 879369106 53,504 130,000 SH   SOLE   130,000 0 0
TG THERAPEUTICS INC COM 88322Q108 25,438 489,000 SH   SOLE   489,000 0 0
THERAVANCE BIOPHARMA INC COM G8807B106 12,052 678,200 SH   SOLE   678,200 0 0
THERAVANCE BIOPHARMA INC NOTE 3.250%11/0 88339KAA0 1,420 1,500,000 PRN   SOLE   1,500,000 0 0
TRANSLATE BIO INC COM 89374L104 11,860 643,500 SH   SOLE   643,500 0 0
TRAVERE THERAPEUTICS INC COM 89422G107 27,827 1,021,000 SH   SOLE   1,021,000 0 0
TRILLIUM THERAPEUTICS INC COM NEW 89620X506 9,098 618,500 SH   SOLE   618,500 0 0
TURMERIC ACQUISITION CORP UNIT 10/08/2025 G9127T116 2,116 206,000 SH   SOLE   206,000 0 0
ULTRAGENYX PHARMACEUTICAL IN COM 90400D108 78,421 566,500 SH   SOLE   566,500 0 0
UNIQURE NV SHS N90064101 7,533 208,500 SH   SOLE   208,500 0 0
UNITEDHEALTH GROUP INC COM 91324P102 142,025 405,000 SH   SOLE   405,000 0 0
WEST PHARMACEUTICAL SVSC INC COM 955306105 8,074 28,500 SH   SOLE   28,500 0 0
XENON PHARMACEUTICALS INC COM 98420N105 7,921 515,000 SH   SOLE   515,000 0 0
ZAI LAB LTD ADR 98887Q104 115,702 854,899 SH   SOLE   854,899 0 0