The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
1Life Healthcare, Inc. Common 68269G107 1,222 31,266 SH   SOLE   31,266 0 0
Abbott Laboratories Common 002824100 89,120 743,657 SH   SOLE   743,657 0 0
AbbVie Inc. Common 00287Y109 67,070 619,759 SH   SOLE   619,759 0 0
ACADIA Pharmaceuticals Inc. Common 004225108 8,560 331,789 SH   SOLE   331,789 0 0
Adaptive Biotechnologies Corp. Common 00650F109 13,597 337,722 SH   SOLE   337,722 0 0
Addus HomeCare Corp. Common 006739106 3,937 37,640 SH   SOLE   37,640 0 0
Affimed N.V. Common N01045108 2,278 288,019 SH   SOLE   288,019 0 0
Agilent Technologies, Inc. Common 00846U101 6,678 52,525 SH   SOLE   52,525 0 0
Alexion Pharmaceuticals, Inc. Common 015351109 16,926 110,693 SH   SOLE   110,693 0 0
Align Technology, Inc. Common 016255101 5,375 9,925 SH   SOLE   9,925 0 0
Alkermes plc Shares G01767105 3,174 169,930 SH   SOLE   169,930 0 0
Allakos Inc. Common 01671P100 18,783 163,645 SH   SOLE   163,645 0 0
Alnylam Pharmaceuticals, Inc. Common 02043Q107 21,871 154,902 SH   SOLE   154,902 0 0
Amedisys, Inc. Common 023436108 5,136 19,395 SH   SOLE   19,395 0 0
Amgen Inc. Common 031162100 103,644 416,560 SH   SOLE   416,560 0 0
Amicus Therapeutics, Inc. Common 03152W109 6,142 621,659 SH   SOLE   621,659 0 0
Anthem, Inc. Common 036752103 59,147 164,777 SH   SOLE   164,777 0 0
Apellis Pharmaceuticals, Inc. Common 03753U106 6,545 152,538 SH   SOLE   152,538 0 0
ARCA biopharma, Inc. Common 00211Y506 118 32,461 SH   SOLE   32,461 0 0
Arcutis Biotherapeutics, Inc. Common 03969K108 3,808 131,633 SH   SOLE   131,633 0 0
Ardelyx, Inc. Common 039697107 4,023 607,698 SH   SOLE   607,698 0 0
Arena Pharmaceuticals, Inc. Common 040047607 13,627 196,385 SH   SOLE   196,385 0 0
Argenx SE Sponsored ADR 04016X101 17,720 64,344 SH   SOLE   64,344 0 0
Arrowhead Pharmaceuticals, Inc. Common 04280A100 8,812 132,886 SH   SOLE   132,886 0 0
Arvinas, Inc. Common 04335A105 5,684 85,997 SH   SOLE   85,997 0 0
Ascendis Pharma A/S Sponsored ADR 04351P101 15,251 118,336 SH   SOLE   118,336 0 0
Assertio Holdings, Inc. Common 04546C106 1,121 1,642,302 SH   SOLE   1,642,302 0 0
AstraZeneca PLC Sponsored ADR 046353108 17,120 344,333 SH   SOLE   344,333 0 0
Atreca, Inc. Class A Common 04965G109 5,403 352,424 SH   SOLE   352,424 0 0
Aurinia Pharmaceuticals Inc. Common 05156V102 5,167 397,920 SH   SOLE   397,920 0 0
Becton, Dickinson and Co. Common 075887109 10,530 43,307 SH   SOLE   43,307 0 0
BeiGene, Ltd. Sponsored ADR 07725L102 14,059 40,389 SH   SOLE   40,389 0 0
Bellicum Pharmaceuticals, Inc. Common 079481404 23 6,000 SH   SOLE   6,000 0 0
Bio-Techne Corp. Common 09073M104 2,903 7,600 SH   SOLE   7,600 0 0
Biogen Inc. Common 09062X103 69,055 246,844 SH   SOLE   246,844 0 0
BioMarin Pharmaceutical Inc. Common 09061G101 9,666 128,004 SH   SOLE   128,004 0 0
BioNTech SE Sponsored ADS 09075V102 7,514 68,814 SH   SOLE   68,814 0 0
Black Diamond Therapeutics, Inc. Common 09203E105 3,202 131,990 SH   SOLE   131,990 0 0
Blueprint Medicines Corp. Common 09627Y109 11,930 122,699 SH   SOLE   122,699 0 0
Boston Scientific Corp. Common 101137107 7,186 185,931 SH   SOLE   185,931 0 0
BridgeBio Pharma, Inc. Common 10806X102 4,602 74,714 SH   SOLE   74,714 0 0
Bristol-Myers Squibb Co. Common 110122108 56,341 892,453 SH   SOLE   892,453 0 0
Catalent, Inc. Common 148806102 8,427 80,025 SH   SOLE   80,025 0 0
Celldex Therapeutics, Inc. Common 15117B202 145 7,053 SH   SOLE   7,053 0 0
Cellectis Sponsored ADR 15117K103 242 11,955 SH   SOLE   11,955 0 0
Centene Corp. Common 15135B101 4,301 67,290 SH   SOLE   67,290 0 0
Charles River Laboratories International, Inc. Common 159864107 12,484 43,074 SH   SOLE   43,074 0 0
ChemoCentryx, Inc. Common 16383L106 7,401 144,447 SH   SOLE   144,447 0 0
Cigna Corp. Common 125523100 45,912 189,921 SH   SOLE   189,921 0 0
Clearside Biomedical, Inc. Common 185063104 408 165,330 SH   SOLE   165,330 0 0
Cogent Biosciences, Inc. Common 19240Q201 4,721 537,742 SH   SOLE   537,742 0 0
Community Health Systems, Inc. Common 203668108 1,589 117,535 SH   SOLE   117,535 0 0
Community Healthcare Trust Inc. Common 20369C106 687 14,900 SH   SOLE   14,900 0 0
Corbus Pharmaceuticals Holdings, Inc. Common 21833P103 815 413,481 SH   SOLE   413,481 0 0
CRISPR Therapeutics AG Namen AKT H17182108 18,394 150,958 SH   SOLE   150,958 0 0
CVS Health Corp. Common 126650100 16,550 219,995 SH   SOLE   219,995 0 0
CymaBay Therapeutics, Inc. Common 23257D103 400 88,102 SH   SOLE   88,102 0 0
Danaher Corp. Common 235851102 43,044 191,240 SH   SOLE   191,240 0 0
Deciphera Pharmaceuticals, Inc. Common 24344T101 13,797 307,703 SH   SOLE   307,703 0 0
Denali Therapeutics Inc. Common 24823R105 8,570 150,086 SH   SOLE   150,086 0 0
DENTSPLY SIRONA Inc. Common 24906P109 22,425 351,427 SH   SOLE   351,427 0 0
Dexcom, Inc. Common 252131107 26,826 74,643 SH   SOLE   74,643 0 0
Dicerna Pharmaceuticals, Inc. Common 253031108 1,743 68,150 SH   SOLE   68,150 0 0
Diversified Healthcare Trust Common 25525P107 1,710 357,720 SH   SOLE   357,720 0 0
Editas Medicine, Inc. Common 28106W103 638 15,190 SH   SOLE   15,190 0 0
Edwards Lifesciences Corp. Common 28176E108 19,969 238,755 SH   SOLE   238,755 0 0
Eli Lilly and Co. Common 532457108 54,573 292,114 SH   SOLE   292,114 0 0
Endo International plc Shares G30401106 3,939 531,570 SH   SOLE   531,570 0 0
Exact Sciences Corp. Common 30063P105 22,047 167,302 SH   SOLE   167,302 0 0
Exelixis, Inc. Common 30161Q104 24,870 1,100,920 SH   SOLE   1,100,920 0 0
Fate Therapeutics, Inc. Common 31189P102 12,396 150,343 SH   SOLE   150,343 0 0
Five Star Senior Living Inc. Common 33832D205 148 24,237 SH   SOLE   24,237 0 0
Forma Therapeutics Holdings, Inc. Shares 34633R104 4,198 149,825 SH   SOLE   149,825 0 0
G1 Therapeutics, Inc. Common 3621LQ109 9,426 391,754 SH   SOLE   391,754 0 0
Galera Therapeutics, Inc. Common 36338D108 9,189 1,041,845 SH   SOLE   1,041,845 0 0
Gamida Cell Ltd. Shares M47364100 956 118,142 SH   SOLE   118,142 0 0
Genmab A/S Sponsored ADS 372303206 2,397 73,015 SH   SOLE   73,015 0 0
Gilead Sciences, Inc. Common 375558103 117,362 1,815,906 SH   SOLE   1,815,906 0 0
Global Medical REIT Inc. Common 37954A204 2,293 174,897 SH   SOLE   174,897 0 0
Grifols, S.A. Sponsored ADR 398438408 819 47,373 SH   SOLE   47,373 0 0
Guardant Health, Inc. Common 40131M109 24,230 158,727 SH   SOLE   158,727 0 0
HCA Healthcare, Inc. Common 40412C101 28,797 152,897 SH   SOLE   152,897 0 0
Health Care Select Sector SPDR Fund SBI Healthcare 81369Y209 1,174 10,055 SH   SOLE   10,055 0 0
Healthcare Realty Trust Inc. Common 421946104 3,154 104,024 SH   SOLE   104,024 0 0
Healthcare Trust of America, Inc. Common 42225P501 1,949 70,662 SH   SOLE   70,662 0 0
Healthpeak Properties, Inc. Common 42250P103 4,773 150,392 SH   SOLE   150,392 0 0
Helix Acquisition Corp. Class A Common G4444C102 2,559 250,000 SH   SOLE   250,000 0 0
Heron Therapeutics, Inc. Common 427746102 2,126 131,183 SH   SOLE   131,183 0 0
Hologic, Inc. Common 436440101 2,422 32,564 SH   SOLE   32,564 0 0
Horizon Therapeutics plc Shares G46188101 74,638 810,932 SH   SOLE   810,932 0 0
Humana Inc. Common 444859102 15,655 37,341 SH   SOLE   37,341 0 0
I-Mab Sponsored ADS 44975P103 8,089 166,896 SH   SOLE   166,896 0 0
Icon plc Shares G4705A100 4,633 23,592 SH   SOLE   23,592 0 0
IDEXX Laboratories, Inc. Common 45168D104 17,035 34,814 SH   SOLE   34,814 0 0
Illumina, Inc. Common 452327109 94,783 246,793 SH   SOLE   246,793 0 0
Incyte Corp. Common 45337C102 8,752 107,687 SH   SOLE   107,687 0 0
Insmed Inc. Common 457669307 3,351 98,387 SH   SOLE   98,387 0 0
Intellia Therapeutics, Inc. Common 45826J105 4,268 53,180 SH   SOLE   53,180 0 0
Intercept Pharmaceuticals, Inc. Common 45845P108 1,779 77,067 SH   SOLE   77,067 0 0
Intra-Cellular Therapies, Inc. Common 46116X101 7,888 232,476 SH   SOLE   232,476 0 0
Intuitive Surgical, Inc. Common 46120E602 15,736 21,296 SH   SOLE   21,296 0 0
Ionis Pharmaceuticals, Inc. Common 462222100 9,728 216,371 SH   SOLE   216,371 0 0
Iovance Biotherapeutics, Inc. Common 462260100 16,482 520,595 SH   SOLE   520,595 0 0
IQVIA Holdings Inc. Common 46266C105 13,494 69,866 SH   SOLE   69,866 0 0
Jazz Pharmaceuticals plc Shares G50871105 11,088 67,456 SH   SOLE   67,456 0 0
Johnson & Johnson Common 478160104 99,409 604,864 SH   SOLE   604,864 0 0
Jounce Therapeutics, Inc. Common 481116101 3,926 382,237 SH   SOLE   382,237 0 0
KalVista Pharmaceuticals, Inc. Common 483497103 1,285 50,000 SH   SOLE   50,000 0 0
Karuna Therapeutics, Inc. Common 48576A100 10,248 85,236 SH   SOLE   85,236 0 0
Koninklijke Philips N.V. NY Reg Sh 500472303 3,247 56,927 SH   SOLE   56,927 0 0
Kura Oncology, Inc. Common 50127T109 7,731 273,463 SH   SOLE   273,463 0 0
Laboratory Corp. of America Holdings Sponsored ADR 50540R409 25,396 99,580 SH   SOLE   99,580 0 0
LTC Properties, Inc. Common 502175102 7,605 182,293 SH   SOLE   182,293 0 0
Madrigal Pharmaceuticals, Inc. Common 558868105 1,560 13,340 SH   SOLE   13,340 0 0
McKesson Corp. Common 58155Q103 24,565 125,948 SH   SOLE   125,948 0 0
Medical Properties Trust, Inc. Common 58463J304 8,762 411,743 SH   SOLE   411,743 0 0
Medpace Holdings, Inc. Common 58506Q109 3,096 18,871 SH   SOLE   18,871 0 0
Medtronic plc Shares G5960L103 58,145 492,214 SH   SOLE   492,214 0 0
Merck & Co., Inc. Common 58933Y105 41,760 541,703 SH   SOLE   541,703 0 0
Mereo BioPharma Group plc ADS 589492107 3,361 997,290 SH   SOLE   997,290 0 0
Mettler-Toledo International Inc. Common 592688105 11,326 9,800 SH   SOLE   9,800 0 0
Mirati Therapeutics, Inc. Common 60468T105 14,352 83,784 SH   SOLE   83,784 0 0
Moderna, Inc. Common 60770K107 61,848 472,302 SH   SOLE   472,302 0 0
Molecular Templates, Inc. Common 608550109 2,517 199,420 SH   SOLE   199,420 0 0
Molina Healthcare, Inc. Common 60855R100 9,296 39,769 SH   SOLE   39,769 0 0
Morphic Holding, Inc. Common 61775R105 5,667 89,559 SH   SOLE   89,559 0 0
MorphoSys AG Sponsored ADS 617760202 1,785 81,867 SH   SOLE   81,867 0 0
National Health Investors, Inc. Common 63633D104 726 10,038 SH   SOLE   10,038 0 0
Nektar Therapeutics Common 640268108 3,609 180,438 SH   SOLE   180,438 0 0
Neurocrine Biosciences, Inc. Common 64125C109 20,704 212,891 SH   SOLE   212,891 0 0
New Senior Investment Group Inc. Common 648691103 1,597 256,398 SH   SOLE   256,398 0 0
Nkarta, Inc. Common 65487U108 954 28,988 SH   SOLE   28,988 0 0
Novartis AG Sponsored ADR 66987V109 11,645 136,225 SH   SOLE   136,225 0 0
Novavax, Inc. Common 670002401 19,069 105,176 SH   SOLE   105,176 0 0
Novo Nordisk A/S Sponsored ADR 670100205 3,264 48,406 SH   SOLE   48,406 0 0
Omega Healthcare Investors, Inc. Common 681936100 11,225 306,433 SH   SOLE   306,433 0 0
Ovid Therapeutics Inc. Sponsored ADR 690469101 1,498 372,733 SH   SOLE   372,733 0 0
Owens & Minor, Inc. Common 690732102 10,000 266,023 SH   SOLE   266,023 0 0
PerkinElmer, Inc. Common 714046109 4,759 37,094 SH   SOLE   37,094 0 0
Perrigo Co. plc Shares G97822103 2,073 51,224 SH   SOLE   51,224 0 0
Personalis, Inc. Common 71535D106 4,423 179,731 SH   SOLE   179,731 0 0
Pfizer Inc. Common 717081103 25,552 705,259 SH   SOLE   705,259 0 0
Physicians Realty Trust Common 71943U104 8,760 495,733 SH   SOLE   495,733 0 0
Pieris Pharmaceuticals, Inc. Common 720795103 2,630 1,023,348 SH   SOLE   1,023,348 0 0
PRA Health Sciences, Inc. Common 69354M108 15,938 103,943 SH   SOLE   103,943 0 0
Praxis Precision Medicines, Inc. Common 74006W108 2,457 75,000 SH   SOLE   75,000 0 0
Precision BioSciences, Inc. Common 74019P108 652 63,001 SH   SOLE   63,001 0 0
R1 RCM Inc. Common 749397105 3,047 123,461 SH   SOLE   123,461 0 0
Reata Pharmaceuticals, Inc. Class A 75615P103 3,810 38,219 SH   SOLE   38,219 0 0
Regeneron Pharmaceuticals, Inc. Common 75886F107 72,629 153,505 SH   SOLE   153,505 0 0
REGENXBIO Inc. Common 75901B107 740 21,700 SH   SOLE   21,700 0 0
Replimune Group, Inc. Common 76029N106 6,684 219,060 SH   SOLE   219,060 0 0
ResMed Inc. Common 761152107 25,677 132,344 SH   SOLE   132,344 0 0
Sabra Health Care REIT, Inc. Common 78573L106 8,865 510,660 SH   SOLE   510,660 0 0
Sage Therapeutics, Inc. Common 78667J108 8,542 114,119 SH   SOLE   114,119 0 0
Sanofi Sponsored ADR 80105N105 4,034 81,554 SH   SOLE   81,554 0 0
Sarepta Therapeutics, Inc. Common 803607100 9,613 128,987 SH   SOLE   128,987 0 0
Scholar Rock Holding Corp. Common 80706P103 2,425 47,869 SH   SOLE   47,869 0 0
Seagen Inc. Common 81181C104 31,312 225,490 SH   SOLE   225,490 0 0
Smith & Nephew plc Shares 83175M205 3,773 99,560 SH   SOLE   99,560 0 0
Spectrum Pharmaceuticals, Inc. Common 84763A108 374 114,670 SH   SOLE   114,670 0 0
STERIS plc Shares G8473T100 24,149 126,779 SH   SOLE   126,779 0 0
Stryker Corp. Common 863667101 36,983 151,830 SH   SOLE   151,830 0 0
Sutro Biopharma, Inc. Common 869367102 13,060 573,823 SH   SOLE   573,823 0 0
Syneos Health, Inc. Class A 87166B102 20,680 272,647 SH   SOLE   272,647 0 0
Takeda Pharmaceutical Co. Ltd. Sponsored ADS 874060205 3,837 210,146 SH   SOLE   210,146 0 0
TCR2 Therapeutics Inc. Common 87808K106 5,207 235,808 SH   SOLE   235,808 0 0
Teladoc Health, Inc. Common 87918A105 5,391 29,664 SH   SOLE   29,664 0 0
Teleflex Inc. Common 879369106 914 2,200 SH   SOLE   2,200 0 0
Tenet Healthcare Corp. Common 88033G407 3,137 60,336 SH   SOLE   60,336 0 0
Tetraphase Pharmaceuticals, Inc. Common 881CVR013 9 42,965 SH   SOLE   42,965 0 0
Teva Pharmaceutical Industries Ltd. Sponsored ADR 881624209 7,623 660,551 SH   SOLE   660,551 0 0
Theravance Biopharma, Inc. Common G8807B106 9,313 456,296 SH   SOLE   456,296 0 0
Thermo Fisher Scientific Inc. Common 883556102 51,869 113,653 SH   SOLE   113,653 0 0
Travere Therapeutics, Inc. Common 89422G107 5,315 212,869 SH   SOLE   212,869 0 0
Trillium Therapeutics Inc. Common 89620X506 5,684 529,226 SH   SOLE   529,226 0 0
Turning Point Therapeutics, Inc. Common 90041T108 11,287 119,324 SH   SOLE   119,324 0 0
Ultragenyx Pharmaceutical Inc. Common 90400D108 11,099 97,480 SH   SOLE   97,480 0 0
uniQure N.V. Shares N90064101 4,211 125,003 SH   SOLE   125,003 0 0
United Therapeutics Corp. Class B 91307C102 10,624 63,513 SH   SOLE   63,513 0 0
Unitedhealth Group Inc. Common 91324P102 78,985 212,285 SH   SOLE   212,285 0 0
Universal Health Realty Income Trust Shares 91359E105 763 11,258 SH   SOLE   11,258 0 0
Universal Health Services, Inc. Class B 913903100 9,514 71,323 SH   SOLE   71,323 0 0
Ventas, Inc. Common 92276F100 11,100 208,108 SH   SOLE   208,108 0 0
Verona Pharma plc Sponsored ADR 925050106 6,286 751,905 SH   SOLE   751,905 0 0
Vertex Pharmaceuticals Inc. Common 92532F100 84,943 395,288 SH   SOLE   395,288 0 0
Vir Biotechnology, Inc. Common 92764N102 4,173 81,400 SH   SOLE   81,400 0 0
VYNE Therapeutics Inc. Common 92941V209 927 135,395 SH   SOLE   135,395 0 0
Waters Corp. Common 941848103 29,187 102,710 SH   SOLE   102,710 0 0
Welltower Inc. Common 95040Q104 14,547 203,083 SH   SOLE   203,083 0 0
Xenon Pharmaceuticals Inc. Common 98420N105 2,970 165,898 SH   SOLE   165,898 0 0
Y-mAbs Therapeutics, Inc. Common 984241109 5,982 197,820 SH   SOLE   197,820 0 0
Zai Lab Ltd. ADR 98887Q104 5,007 37,523 SH   SOLE   37,523 0 0
Zimmer Biomet Holdings, Inc. Common 98956P102 33,267 207,814 SH   SOLE   207,814 0 0
Zoetis Inc. Class A 98978V103 8,901 56,521 SH   SOLE   56,521 0 0
Zogenix, Inc. Common 98978L204 1,737 88,977 SH   SOLE   88,977 0 0