The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
21VIANET GROUP INC SPONSORED ADS A 90138A103 80,124 2,480,611 SH   DFND 9,27 2,480,611 0 0
AC IMMUNE SA SHS H00263105 19,893 2,614,095 SH   DFND 14,26,31 2,614,095 0 0
ADOBE SYSTEMS INCORPORATED COM 00724F101 45,607 95,940 SH   DFND 1,22,25 95,940 0 0
ALIBABA GROUP HLDG LTD SPONSORED ADS 01609W102 2,709,686 11,951,157 SH   DFND 1,7,22,23,25 11,951,157 0 0
AFFIRM HLDGS INC COM CL A 00827B106 1,101 15,570 SH   DFND 13,15 15,570 0 0
AMAZON COM INC COM 023135106 429,978 138,968 SH   DFND 1,10,22,25 138,968 0 0
ASLAN PHARMACEUTICALS LTD ADS 04522R101 5,622 1,678,075 SH   DFND 1,14,22,25,26,31 1,678,075 0 0
BEAM THERAPEUTICS INC COM 07373V105 272,617 3,406,013 SH   DFND 13,14,15,26,29 3,406,013 0 0
BEIGENE LTD SPONSORED ADR 07725L102 956,090 2,746,755 SH   DFND 1,14,22,25,26,31 2,746,755 0 0
BILL COM HLDGS INC COM 090043100 808,405 5,556,050 SH   DFND 14,16,20 5,556,050 0 0
BIONTECH SE SPONSORED ADS 09075V102 58,704 537,634 SH   DFND 2,8,27 537,634 0 0
BLACKROCK INC COM 09247X101 4,487,856 5,952,380 SH   DFND 1,9,22,25,27 5,952,380 0 0
CHENIERE ENERGY INC DEBT 4.875% 5/2 U16344AB6 272,903 268,209,445 PRN   DFND 3,7,22,25 268,209,445 0 0
CHINA BIOLOGIC PRODS HLDGS I COM G21515104 146,828 1,240,000 SH   DFND 14,26,31 1,240,000 0 0
COHERUS BIOSCIENCES INC COM 19249H103 107,838 7,381,116 SH   DFND 14,26,31 7,381,116 0 0
CONTEXTLOGIC INC COM CL A 21077C107 423,991 26,834,880 SH   DFND 21,22,25 26,834,880 0 0
CORTEVA INC COM 22052L104 87,336 1,873,363 SH   DFND 10,25 1,873,363 0 0
DATADOG INC CL A COM 23804L103 6,270 75,237 SH   DFND 13,15 75,237 0 0
DELL TECHNOLOGIES INC CL C 24703L202 779,964 8,848,147 SH   DFND 19,27,30 8,848,147 0 0
DENALI THERAPEUTICS INC COM 24823R105 251,837 4,410,457 SH   DFND 14,26,29,31 4,410,457 0 0
DOORDASH INC CL A 25809K105 662,074 5,048,988 SH   DFND 6,13,27,28 5,048,988 0 0
DUCK CREEK TECHNOLOGIES INC SHS 264120106 236,599 5,241,451 SH   DFND 1,4,13,22,25 5,241,451 0 0
EROS STX GLOBAL CORPORATION SHS NEW G3788M114 4,987 2,755,310 SH   DFND 7,22,25 2,755,310 0 0
FARFETCH LTD ORD SH CL A 30744W107 34,048 642,168 SH   DFND 21,22,25 642,168 0 0
GLOBAL PMTS INC COM 37940X102 196,753 976,055 SH   DFND 1,14,17,22,25 976,055 0 0
GRACE W R & CO DEL NEW COM 38388F108 130,944 2,187,501 SH   DFND 10,25 2,187,501 0 0
GRACELL BIOTECHNOLOGIES INC SPONSORED ADS 38406L103 4,053 263,158 SH   DFND 14,26,29 263,158 0 0
GUARDANT HEALTH INC COM 40131M109 246,226 1,613,007 SH   DFND 14,26,29 1,613,007 0 0
HDFC BANK LTD SPONSORED ADS 40415F101 378,718 4,874,732 SH   DFND 1,10,22,25 4,874,732 0 0
HOMOLOGY MEDICINES INC COM 438083107 30,303 3,220,293 SH   DFND 14,26,29,31 3,220,293 0 0
ICICI BANK LIMITED ADR 45104G104 364,429 22,734,192 SH   DFND 1,5,10,14,22,25 22,734,192 0 0
IHS MARKIT LTD SHS G47567105 973,594 10,059,869 SH   DFND 9,27 10,059,869 0 0
ILLUMINA INC COM 452327109 21,297 55,452 SH   DFND 1,22,25 55,452 0 0
INTELLIA THERAPEUTICS INC COM 45826J105 63,444 790,527 SH   DFND 10,14,25,26,29 790,527 0 0
ISHARES GOLD TR ISHARES 464285105 112,518 6,919,920 SH   DFND 1,22,25 6,919,920 0 0
ISHARES INC MSCI STH KOR ETF 464286772 113,632 1,266,800 SH   DFND 1,22,25 1,266,800 0 0
ISHARES INC MSCI TAIWAN ETF 46434G772 48,604 810,600 SH   DFND 1,22,25 810,600 0 0
ISHARES INC MSCI BRAZIL ETF 464286400 30,364 907,728 SH   DFND 1,22,25 907,728 0 0
ISHARES TR RUSSELL 2000 ETF 464287655 117,518 531,900 SH   DFND 1,22,25 531,900 0 0
ISHARES TR MSCI INDIA ETF 46429B598 37,034 878,000 SH   DFND 1,22,25 878,000 0 0
ISHARES TR US TREAS BD ETF 46429B267 18,595 710,000 SH   DFND 1,22,25 710,000 0 0
KARUNA THERAPEUTICS INC COM 48576A100 772 6,422 SH   DFND 13,15 6,422 0 0
KEURIG DR PEPPER INC COM 49271V100 236,385 6,877,661 SH   DFND 13,15 6,877,661 0 0
KKR REAL ESTATE FIN TR INC COM 48251K100 44,854 2,439,024 SH   DFND 1,22,25 2,439,024 0 0
LEMONADE INC COM 52567D107 370 3,978 SH   DFND 13,15 3,978 0 0
LUMEN TECHNOLOGIES INC COM 550241103 1,298,413 97,259,407 SH   DFND 1,2,8,11,22,25,27 97,259,407 0 0
MASTERCARD INCORPORATED CL A 57636Q104 1,030,754 2,894,970 SH   DFND 1,14,17,22,25 2,894,970 0 0
MICROSOFT CORP COM 594918104 72,946 309,396 SH   DFND 1,22,25 309,396 0 0
ORCHARD THERAPEUTICS PLC ADS 68570P101 7,260 1,000,000 SH   DFND 14,26,31 1,000,000 0 0
PAYPAL HLDGS INC COM 70450Y103 2,307,656 9,502,785 SH   DFND 1,7,14,17,22,24,25 9,502,785 0 0
PINDUODUO INC SPONSORED ADS 722304102 2,381 17,783 SH   DFND 4,13,15 17,783 0 0
ROBLOX CORP CL A 771049103 896,734 13,832,090 SH   DFND 1,13,15,22,25,27,28 13,832,090 0 0
SALESFORCE COM INC COM 79466L302 33,009 155,797 SH   DFND 1,22,25 155,797 0 0
SCHWAB STRATEGIC TR US TIPS ETF 808524870 83,875 1,371,400 SH   DFND 1,22,25 1,371,400 0 0
SEA LTD SPONSORD ADS 81141R100 186,175 834,005 SH   DFND 1,10,22,25 834,005 0 0
SELECT SECTOR SPDR TR SBI INT-FINL 81369Y605 123,343 3,622,400 SH   DFND 1,22,25 3,622,400 0 0
SELECT SECTOR SPDR TR SBI MATERIALS 81369Y100 129,498 1,643,380 SH   DFND 1,22,25 1,643,380 0 0
SNOWFLAKE INC CL A 833445109 294,064 1,282,554 SH   DFND 1,10,13,15,22,25 1,282,554 0 0
SQZ BIOTECHNOLOGIES CO COM 78472W104 34,390 2,513,924 SH   DFND 14,26,31 2,513,924 0 0
STARBUCKS CORP COM 855244109 58,714 537,333 SH   DFND 10,25 537,333 0 0
TAL EDUCATION GROUP SPONSORED ADS 874080104 19,935 370,200 SH   DFND 1,22,25 370,200 0 0
TENCENT MUSIC ENTMT GROUP SPON ADS 88034P109 232 11,313 SH   DFND 13,15 11,313 0 0
THERMO FISHER SCIENTIFIC INC COM 883556102 685,979 1,503,087 SH   DFND 5,14,18 1,503,087 0 0
UBER TECHNOLOGIES INC COM 90353T100 1,824 33,455 SH   DFND 13,15 33,455 0 0
VAXCYTE INC COM 92243G108 539 27,272 SH   DFND 13,15 27,272 0 0
VIR BIOTECHNOLOGY INC COM 92764N102 282,941 5,518,644 SH   DFND 13,14,15,26,29,31 5,518,644 0 0
VIRTU FINL INC CL A 928254101 198,115 6,380,503 SH   DFND 13,15 6,380,503 0 0
VISA INC COM CL A 92826C839 1,257,080 5,937,184 SH   DFND 1,14,17,22,25 5,937,184 0 0
VMWARE INC CL A COM 928563402 101,497 674,623 SH   DFND 10,25 674,623 0 0
ZOOM VIDEO COMMUNICATIONS IN CL A 98980L101 1,212 3,772 SH   DFND 13,15 3,772 0 0
ZTO EXPRESS CAYMAN INC SPONSORED ADS A 98980A105 354,952 12,176,750 SH   DFND 1,22,25 12,176,750 0 0