The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ACCELERON PHARMA INC COM 00434H108 27,545 219,500 SH   DFND 1 219,500 0 0
ACHILLES THERAPEUTICS PLC SPONSORED ADS 00449L102 2,951 301,431 SH   DFND 1 301,431 0 0
ACUTUS MED INC COM 005111109 73,724 4,341,799 SH   DFND 1 4,341,799 0 0
ADAPTHEALTH CORP COM CL A 00653Q102 201,567 7,353,792 SH   DFND 1 7,353,792 0 0
ADVERUM BIOTECHNOLOGIES INC COM 00773U108 9,895 2,827,000 SH   DFND 1 2,827,000 0 0
AERIE PHARMACEUTICALS INC NOTE 1.500%10/0 00771VAB4 156,612 157,390,000 PRN   DFND 1 157,390,000 0 0
AERIE PHARMACEUTICALS INC COM 00771V108 13,223 825,937 SH   DFND 1 825,937 0 0
AEROVATE THERAPEUTICS INC COM 008064107 16,307 714,285 SH   DFND 1 714,285 0 0
AGILON HEALTH INC COM 00857U107 12,171 300,000 SH   DFND 1 300,000 0 0
ALECTOR INC COM 014442107 21,980 1,055,192 SH   DFND 1 1,055,192 0 0
ALPHATEC HLDGS INC COM NEW 02081G201 52,125 3,402,384 SH   DFND 1 3,402,384 0 0
AMERICAN WELL CORP CL A 03044L105 12,468 991,115 SH   DFND 1 991,115 0 0
AMICUS THERAPEUTICS INC COM 03152W109 28,356 2,941,492 SH   DFND 1 2,941,492 0 0
ANNEXON INC COM 03589W102 13,144 583,913 SH   DFND 1 583,913 0 0
APELLIS PHARMACEUTICALS INC NOTE 3.500% 9/1 03753UAB2 77,769 41,825,000 PRN   DFND 1 41,825,000 0 0
APRIA INC COM 03836A101 44,041 1,572,892 SH   DFND 1 1,572,892 0 0
ARDELYX INC COM 039697107 28,892 3,811,554 SH   DFND 1 3,811,554 0 0
AVEANNA HEALTHCARE HLDGS INC COM 05356F105 24,740 2,000,000 SH   DFND 1 2,000,000 0 0
AVIDITY BIOSCIENCES INC COM 05370A108 13,841 560,132 SH   DFND 1 560,132 0 0
BENEFITFOCUS INC NOTE 1.250%12/1 08180DAB2 6,130 6,500,000 PRN   DFND 1 6,500,000 0 0
BIOATLA INC COM 09077B104 10,399 245,381 SH   DFND 1 245,381 0 0
BIOCRYST PHARMACEUTICALS INC COM 09058V103 44,821 2,835,000 SH   DFND 1 2,835,000 0 0
BIODELIVERY SCIENCES INTL IN COM 09060J106 34,117 9,530,000 SH   DFND 1 9,530,000 0 0
BIOMEA FUSION INC COM 09077A106 3,878 248,447 SH   DFND 1 248,447 0 0
BIOVENTUS INC COM CL A 09075A108 13,703 778,567 SH   DFND 1 778,567 0 0
BLACK DIAMOND THERAPEUTICS I COM 09203E105 12,770 1,047,599 SH   DFND 1 1,047,599 0 0
BLUEBIRD BIO INC COM 09609G100 15,360 480,300 SH   DFND 1 480,300 0 0
BLUEPRINT MEDICINES CORP COM 09627Y109 24,783 281,754 SH   DFND 1 281,754 0 0
BRIDGEBIO PHARMA INC NOTE 2.500% 3/1 10806XAB8 131,241 80,000,000 PRN   DFND 1 80,000,000 0 0
BRIGHT HEALTH GROUP INC COM 10920V107 24,024 1,400,000 SH   DFND 1 1,400,000 0 0
BROOKDALE SR LIVING INC COM 112463104 26,054 3,298,000 SH   DFND 1 3,298,000 0 0
BUTTERFLY NETWORK INC *W EXP 02/12/202 124155110 3,542 733,333 SH   DFND 1 733,333 0 0
CABALETTA BIO INC COM 12674W109 3,993 464,252 SH   DFND 1 464,252 0 0
CAREMAX INC COM CL A 14171W103 216,446 16,778,750 SH   DFND 1 16,778,750 0 0
CAREMAX INC *W EXP 06/08/202 14171W111 3,172 672,000 SH   DFND 1 672,000 0 0
CENTENE CORP DEL COM 15135B101 72,565 995,000 SH   DFND 1 995,000 0 0
CEREVEL THERAPEUTICS HLDNG I *W EXP 06/09/202 15678U102 2,398 166,666 SH   DFND 1 166,666 0 0
CHIMERIX INC COM 16934W106 14,530 1,816,221 SH   DFND 1 1,816,221 0 0
CLOVIS ONCOLOGY INC NOTE 2.500% 9/1 189464AB6 47,809 49,064,000 PRN   DFND 1 49,064,000 0 0
CM LIFE SCIENCES II INC UNIT 02/25/2028 125842203 8,070 600,000 SH   DFND 1 600,000 0 0
COGENT BIOSCIENCES INC COM 19240Q201 12,984 1,601,000 SH   DFND 1 1,601,000 0 0
CONSONANCE HFW ACQUISITION C UNIT 99/99/9999 G2445M129 5,200 500,000 SH   DFND 1 500,000 0 0
CONSTELLATION PHARMCETICLS I COM 210373106 54,128 1,601,427 SH   DFND 1 1,601,427 0 0
CONVEY HLDG PARENT INC COM 21258C108 12,518 1,100,000 SH   DFND 1 1,100,000 0 0
CULLINAN ONCOLOGY INC COM 230031106 26,883 1,044,000 SH   DFND 1 1,044,000 0 0
CVRX INC COM 126638105 11,200 400,000 SH   DFND 1 400,000 0 0
CYTOKINETICS INC COM NEW 23282W605 24,502 1,238,083 SH   DFND 1 1,238,083 0 0
DAY ONE BIOPHARMACEUTICALS I COM 23954D109 18,648 818,980 SH   DFND 1 818,980 0 0
DECIPHERA PHARMACEUTICALS IN COM 24344T101 49,188 1,343,560 SH   DFND 1 1,343,560 0 0
DELCATH SYS INC COM NEW 24661P807 6,305 500,000 SH   DFND 1 500,000 0 0
DFP HEALTHCARE ACQUISITNS CO COM CL A 23343Q100 49,750 5,000,000 SH   DFND 1 5,000,000 0 0
DFP HEALTHCARE ACQUISITNS CO *W EXP 03/31/202 23343Q118 2,163 1,250,000 SH   DFND 1 1,250,000 0 0
DYNE THERAPEUTICS INC COM 26818M108 16,558 787,000 SH   DFND 1 787,000 0 0
EDGEWISE THERAPEUTICS INC COM 28036F105 83,894 3,933,137 SH   DFND 1 3,933,137 0 0
ENVISTA HOLDINGS CORPORATION NOTE 2.375% 6/0 29415FAB0 112,018 52,500,000 PRN   DFND 1 52,500,000 0 0
EUCRATES BIOMEDICAL ACQU COR UNIT 10/23/2027 G3141W114 10,200 1,000,000 SH   DFND 1 1,000,000 0 0
FATE THERAPEUTICS INC COM 31189P102 26,384 304,000 SH   DFND 1 304,000 0 0
GALAPAGOS NV SPON ADR 36315X101 45,261 657,005 SH   DFND 1 657,005 0 0
GH RESEARCH PLC ORDINARY SHARES G3855L106 12,069 555,416 SH   DFND 1 555,416 0 0
GLAUKOS CORP NOTE 2.750% 6/1 377322AB8 153,534 90,000,000 PRN   DFND 1 90,000,000 0 0
GRAPHITE BIO INC COM 38870X104 27,851 906,308 SH   DFND 1 906,308 0 0
GRAYBUG VISION INC COM SHS 38942Q103 28,680 5,281,713 SH   DFND 1 5,281,713 0 0
HEALTH CATALYST INC NOTE 2.500% 4/1 42225TAB3 28,740 15,000,000 PRN   DFND 1 15,000,000 0 0
IGNYTE ACQUISITION CORP UNIT 01/05/2026 45175H205 7,265 725,000 SH   DFND 1 725,000 0 0
IMMUNOCORE HLDGS PLC ADS 45258D105 14,096 360,966 SH   DFND 1 360,966 0 0
INOZYME PHARMA INC COM 45790W108 37,130 2,178,985 SH   DFND 1 2,178,985 0 0
INSMED INC NOTE 1.750% 1/1 457669AA7 52,525 50,000,000 PRN   DFND 1 50,000,000 0 0
INSMED INC COM PAR $.01 457669307 5,692 200,000 SH   DFND 1 200,000 0 0
INSMED INC NOTE 0.750% 6/0 457669AB5 55,522 50,000,000 PRN   DFND 1 50,000,000 0 0
INSTIL BIO INC COM 45783C101 21,556 1,115,739 SH   DFND 1 1,115,739 0 0
INSULET CORP NOTE 0.375% 9/0 45784PAK7 78,182 57,581,000 PRN   DFND 1 57,581,000 0 0
INTERCEPT PHARMACEUTICALS IN NOTE 3.250% 7/0 45845PAA6 51,920 57,791,000 PRN   DFND 1 57,791,000 0 0
INTERSECT ENT INC COM 46071F103 4,366 255,456 SH   DFND 1 255,456 0 0
INVITAE CORP NOTE 2.000% 9/0 46185LAB9 221,666 163,385,000 PRN   DFND 1 163,385,000 0 0
ITAMAR MED LTD SPONSORED ADS 465437101 28,114 1,193,803 SH   DFND 1 1,193,803 0 0
IVERIC BIO INC COM 46583P102 36,392 5,767,409 SH   DFND 1 5,767,409 0 0
JANUX THERAPEUTICS INC COM 47103J105 17,465 700,000 SH   DFND 1 700,000 0 0
KALVISTA PHARMACEUTICALS INC COM 483497103 51,839 2,163,554 SH   DFND 1 2,163,554 0 0
KINNATE BIOPHARMA INC COM 49705R105 23,746 1,020,000 SH   DFND 1 1,020,000 0 0
KURA ONCOLOGY INC COM 50127T109 37,405 1,794,000 SH   DFND 1 1,794,000 0 0
LARIMAR THERAPEUTICS INC COM 517125100 57,253 5,830,249 SH   DFND 1 5,830,249 0 0
LIFESTANCE HEALTH GROUP INC COM 53228F101 11,144 400,000 SH   DFND 1 400,000 0 0
LUMOS PHARMA INC COM 55028X109 331 33,117 SH   DFND 1 33,117 0 0
MEDAVAIL HOLDINGS INC COM 58406B103 13,996 1,142,552 SH   DFND 1 1,142,552 0 0
MEDTECH ACQUISITION CORP UNIT 12/18/2025 58507N204 10,020 1,000,000 SH   DFND 1 1,000,000 0 0
MERIDIAN BIOSCIENCE INC COM 589584101 31,590 1,424,274 SH   DFND 1 1,424,274 0 0
METACRINE INC COM 59101E103 1,054 277,469 SH   DFND 1 277,469 0 0
MIRUM PHARMACEUTICALS INC COM 604749101 59,632 3,448,912 SH   DFND 1 3,448,912 0 0
MOLINA HEALTHCARE INC COM 60855R100 58,653 231,776 SH   DFND 1 231,776 0 0
MONTE ROSA THERAPEUTICS INC COM 61225M102 7,945 350,000 SH   DFND 1 350,000 0 0
MONTES ARCHIMEDES ACQUISITIO UNIT 09/30/2025 612657205 21,320 2,000,000 SH   DFND 1 2,000,000 0 0
NATERA INC NOTE 2.250% 5/0 632307AB0 136,309 45,000,000 PRN   DFND 1 45,000,000 0 0
NEOGENOMICS INC NOTE 0.250% 1/1 64049MAB6 2,452 2,500,000 PRN   DFND 1 2,500,000 0 0
NEUROCRINE BIOSCIENCES INC COM 64125C109 70,557 725,000 SH   DFND 1 725,000 0 0
NEVRO CORP NOTE 2.750% 4/0 64157FAC7 20,863 12,000,000 PRN   DFND 1 12,000,000 0 0
NOVAVAX INC NOTE 3.750% 2/0 670002AB0 44,647 25,000,000 PRN   DFND 1 25,000,000 0 0
NUVASIVE INC NOTE 0.375% 3/1 670704AJ4 39,639 40,000,000 PRN   DFND 1 40,000,000 0 0
NUVASIVE INC NOTE 1.000% 6/0 670704AL9 101,298 96,966,000 PRN   DFND 1 96,966,000 0 0
NUVATION BIO INC COM CL A 67080N101 33,304 3,577,233 SH   DFND 1 3,577,233 0 0
NUVATION BIO INC *W EXP 07/07/202 67080N119 433 166,666 SH   DFND 1 166,666 0 0
OLEMA PHARMACEUTICALS INC COM 68062P106 7,588 271,191 SH   DFND 1 271,191 0 0
ONCORUS INC COM 68236R103 43,456 3,148,977 SH   DFND 1 3,148,977 0 0
ORCHARD THERAPEUTICS PLC ADS 68570P101 30,508 6,949,416 SH   DFND 1 6,949,416 0 0
ORGANOGENESIS HLDGS INC COM 68621F102 120,032 7,222,127 SH   DFND 1 7,222,127 0 0
ORION ACQUISITION CORP UNIT 02/19/2026 68626A207 4,960 500,000 SH   DFND 1 500,000 0 0
OUTSET MED INC COM 690145107 20,023 400,622 SH   DFND 1 400,622 0 0
OWENS & MINOR INC NEW COM 690732102 42,182 996,500 SH   DFND 1 996,500 0 0
PACIRA BIOSCIENCES INC COM 695127100 69,600 1,147,000 SH   DFND 1 1,147,000 0 0
PHARVARIS N V COM N69605108 19,240 1,032,757 SH   DFND 1 1,032,757 0 0
PMV PHARMACEUTICALS INC COM 69353Y103 27,465 804,000 SH   DFND 1 804,000 0 0
PRIVIA HEALTH GROUP INC COM 74276R102 13,311 300,000 SH   DFND 1 300,000 0 0
PROFOUND MED CORP COM NEW 74319B502 21,232 1,297,797 SH   DFND 1 1,297,797 0 0
PROTAGONIST THERAPEUTICS INC COM 74366E102 61,162 1,362,790 SH   DFND 1 1,362,790 0 0
PTC THERAPEUTICS INC NOTE 3.000% 8/1 69366JAB7 15,558 14,527,000 PRN   DFND 1 14,527,000 0 0
PULMONX CORP COM 745848101 79,455 1,800,887 SH   DFND 1 1,800,887 0 0
PUMA BIOTECHNOLOGY INC COM 74587V107 34,607 3,769,795 SH   DFND 1 3,769,795 0 0
QUANTUM SI INC COM CL A 74765K105 17,164 1,400,000 SH   DFND 1 1,400,000 0 0
QUANTUM SI INC *W EXP 06/10/202 74765K113 1,253 333,333 SH   DFND 1 333,333 0 0
QUIDEL CORP COM 74838J101 52,429 409,219 SH   DFND 1 409,219 0 0
REATA PHARMACEUTICALS INC CL A 75615P103 42,459 300,000 SH   DFND 1 300,000 0 0
RENEO PHARMACEUTICALS INC COM 75974E103 7,924 849,300 SH   DFND 1 849,300 0 0
REVOLUTION HEALTHCAR AQ CORP UNIT 03/18/20266 76155Y207 10,080 1,000,000 SH   DFND 1 1,000,000 0 0
REVOLUTION MEDICINES INC COM 76155X100 49,696 1,565,712 SH   DFND 1 1,565,712 0 0
RHYTHM PHARMACEUTICALS INC COM 76243J105 38,957 1,989,625 SH   DFND 1 1,989,625 0 0
SARISSA CAPITAL ACQUISITN CO UNIT 10/23/2027 G7823W128 10,420 1,000,000 SH   DFND 1 1,000,000 0 0
SENIOR CONNECT ACQUISITN COR UNIT 12/09/2023 81723H207 10,120 1,000,000 SH   DFND 1 1,000,000 0 0
SILK RD MED INC COM 82710M100 54,490 1,138,525 SH   DFND 1 1,138,525 0 0
SINGULAR GENOMICS SYSTEMS IN COM 82933R100 250,398 9,112,019 SH   DFND 1 9,112,019 0 0
SPRINGWORKS THERAPEUTICS INC COM 85205L107 46,032 558,574 SH   DFND 1 558,574 0 0
SPRUCE BIOSCIENCES INC COM 85209E109 22,946 2,046,958 SH   DFND 1 2,046,958 0 0
STEREOTAXIS INC COM NEW 85916J409 17,767 1,843,000 SH   DFND 1 1,843,000 0 0
TABULA RASA HEALTHCARE INC NOTE 1.750% 2/1 873379AA9 45,640 45,000,000 PRN   DFND 1 45,000,000 0 0
TALKSPACE INC COM 87427V103 6,233 750,000 SH   DFND 1 750,000 0 0
TERNS PHARMACEUTICALS INC COM 880881107 28,761 2,345,959 SH   DFND 1 2,345,959 0 0
TURMERIC ACQUISITION CORP UNIT 10/08/2025 G9127T116 7,545 750,000 SH   DFND 1 750,000 0 0
TURNING POINT THERAPEUTICS I COM 90041T108 6,542 83,846 SH   DFND 1 83,846 0 0
VIATRIS INC COM 92556V106 268,995 18,824,000 SH   DFND 1 18,824,000 0 0
WAVE LIFE SCIENCES LTD SHS Y95308105 32,162 4,829,069 SH   DFND 1 4,829,069 0 0
WEREWOLF THERAPEUTICS INC COM 95075A107 44,521 2,552,787 SH   DFND 1 2,552,787 0 0
WINDTREE THERAPEUTICS INC COM 97382D303 46 20,148 SH   DFND 1 20,148 0 0
XERIS PHARMACEUTICALS INC NOTE 5.000% 7/1 98422LAA5 28,545 18,000,000 PRN   DFND 1 18,000,000 0 0
XERIS PHARMACEUTICALS INC COM 98422L107 26,672 6,553,398 SH   DFND 1 6,553,398 0 0
ZIMMER BIOMET HOLDINGS INC COM 98956P102 54,357 338,000 SH   DFND 1 338,000 0 0