The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ABCAM PLC ADS 000380204 20,896 1,097,500 SH   SOLE   1,097,500 0 0
ACADIA HEALTHCARE COMPANY IN COM 00404A109 43,925 700,000 SH   SOLE   700,000 0 0
ACADIA PHARMACEUTICALS INC COM 004225108 24,390 1,000,000 SH   SOLE   1,000,000 0 0
ACCOLADE INC COM 00437E102 36,116 665,000 SH   SOLE   665,000 0 0
ACELRX PHARMACEUTICALS INC COM 00444T100 5,228 3,788,757 SH   SOLE   3,788,757 0 0
ACLARIS THERAPEUTICS INC COM 00461U105 66,066 3,762,312 SH   SOLE   3,762,312 0 0
ADAPTIMMUNE THERAPEUTICS PLC SPONDS ADR 00653A107 6,582 1,545,000 SH   SOLE   1,545,000 0 0
ADAPTIVE BIOTECHNOLOGIES COR COM 00650F109 26,559 650,000 SH   SOLE   650,000 0 0
AEGLEA BIOTHERAPEUTICS INC COM 00773J103 10,978 1,577,296 SH   SOLE   1,577,296 0 0
AERPIO PHARMACEUTICALS INC COM 00810B105 225 133,375 SH   SOLE   133,375 0 0
AGILON HEALTH INC COM 00857U107 283,950 6,999,023 SH   SOLE   6,999,023 0 0
AGIOS PHARMACEUTICALS INC COM 00847X104 141,870 2,574,308 SH   SOLE   2,574,308 0 0
AKERO THERAPEUTICS INC COM 00973Y108 13,115 528,601 SH   SOLE   528,601 0 0
ALIGN TECHNOLOGY INC COM 016255101 114,715 187,750 SH   SOLE   187,750 0 0
ALLAKOS INC COM 01671P100 26,098 305,706 SH   SOLE   305,706 0 0
ALNYLAM PHARMACEUTICALS INC COM 02043Q107 50,856 300,000 SH   SOLE   300,000 0 0
AMARIN CORP PLC SPONS ADR NEW 023111206 18,922 4,320,000 SH   SOLE   4,320,000 0 0
AMICUS THERAPEUTICS INC COM 03152W109 9,761 1,012,506 SH   SOLE   1,012,506 0 0
ANAPTYSBIO INC COM 032724106 13,879 535,232 SH   SOLE   535,232 0 0
APELLIS PHARMACEUTICALS INC COM 03753U106 9,979 157,900 SH Call SOLE   157,900 0 0
APPLIED THERAPEUTICS INC COM 03828A101 14,581 701,680 SH   SOLE   701,680 0 0
ARDELYX INC COM 039697107 39,786 5,248,829 SH   SOLE   5,248,829 0 0
ARGENX SE SPONSORED ADR 04016X101 94,837 315,000 SH   SOLE   315,000 0 0
ARVINAS INC COM 04335A105 48,210 626,100 SH   SOLE   626,100 0 0
ASCENDIS PHARMA A/S SPONSORED ADR 04351P101 30,717 233,500 SH   SOLE   233,500 0 0
ATAI LIFE SCIENCES NV SHS N0731H103 5,828 315,028 SH   SOLE   315,028 0 0
ATEA PHARMACEUTICALS INC COM 04683R106 16,994 791,133 SH   SOLE   791,133 0 0
ATHIRA PHARMA INC COM 04746L104 7,662 748,202 SH   SOLE   748,202 0 0
ATRECA INC CL A COM 04965G109 3,918 459,830 SH   SOLE   459,830 0 0
AURINIA PHARMACEUTICALS INC COM 05156V102 10,184 785,769 SH   SOLE   785,769 0 0
BCLS ACQUISITION CORP COM CL A G0904B105 3,254 309,000 SH   SOLE   309,000 0 0
BEIGENE LTD SPONSORED ADR 07725L102 68,638 200,000 SH   SOLE   200,000 0 0
BIOGEN INC COM 09062X103 39,302 113,500 SH   SOLE   113,500 0 0
BIOMARIN PHARMACEUTICAL INC COM 09061G101 21,152 253,500 SH   SOLE   253,500 0 0
BIOMEA FUSION INC COM 09077A106 18,194 1,165,582 SH   SOLE   1,165,582 0 0
BLUEPRINT MEDICINES CORP COM 09627Y109 71,147 808,860 SH   SOLE   808,860 0 0
BOLT BIOTHERAPEUTICS INC COM 097702104 25,034 1,619,248 SH   SOLE   1,619,248 0 0
BOSTON SCIENTIFIC CORP COM 101137107 34,208 800,000 SH   SOLE   800,000 0 0
BRIGHT HEALTH GROUP INC COM 10920V107 40,755 2,375,000 SH   SOLE   2,375,000 0 0
CEREVEL THERAPEUTICS HLDNG I COM 15678U128 26,054 1,016,945 SH   SOLE   1,016,945 0 0
CHIASMA INC COM 16706W102 15,411 3,258,144 SH   SOLE   3,258,144 0 0
CHINOOK THERAPEUTICS INC COM 16961L106 9,636 682,449 SH   SOLE   682,449 0 0
COLLEGIUM PHARMACEUTICAL INC COM 19459J104 21,749 920,000 SH   SOLE   920,000 0 0
COMPUGEN LTD ORD M25722105 10,242 1,236,988 SH   SOLE   1,236,988 0 0
CONMED CORP COM 207410101 22,332 162,500 SH   SOLE   162,500 0 0
CONSTELLATION PHARMCETICLS I COM 210373106 8,355 247,200 SH   SOLE   247,200 0 0
COVETRUS INC COM 22304C100 39,285 1,455,000 SH   SOLE   1,455,000 0 0
CULLINAN ONCOLOGY INC COM 230031106 27,705 1,075,912 SH   SOLE   1,075,912 0 0
CYTOKINETICS INC NOTE 4.000%11/1 23282WAA8 16,570 8,000,000 PRN   SOLE   8,000,000 0 0
DAY ONE BIOPHARMACEUTICALS I COM 23954D109 8,510 373,739 SH   SOLE   373,739 0 0
DESIGN THERAPEUTICS INC COM 25056L103 6,604 332,050 SH   SOLE   332,050 0 0
DEXCOM INC COM 252131107 19,471 45,600 SH   SOLE   45,600 0 0
DYNAVAX TECHNOLOGIES CORP COM NEW 268158201 16,547 1,679,921 SH   SOLE   1,679,921 0 0
EARGO INC COM 270087109 57,870 1,450,000 SH   SOLE   1,450,000 0 0
EDAP TMS S A SPONSORED ADR 268311107 5,395 760,900 SH   SOLE   760,900 0 0
EDWARDS LIFESCIENCES CORP COM 28176E108 60,278 582,000 SH   SOLE   582,000 0 0
ENCOMPASS HEALTH CORP COM 29261A100 39,015 500,000 SH   SOLE   500,000 0 0
EPIZYME INC COM 29428V104 25,025 3,011,487 SH   SOLE   3,011,487 0 0
ESSA PHARMA INC COM NEW 29668H708 14,372 503,035 SH   SOLE   503,035 0 0
EUCRATES BIOMEDICAL ACQU COR UNIT 10/23/2027 G3141W114 2,101 206,000 SH   SOLE   206,000 0 0
EVOLENT HEALTH INC CL A 30050B101 35,884 1,699,043 SH   SOLE   1,699,043 0 0
EXACT SCIENCES CORP COM 30063P105 70,857 570,000 SH   SOLE   570,000 0 0
FATE THERAPEUTICS INC COM 31189P102 6,075 70,000 SH   SOLE   70,000 0 0
FIBROGEN INC COM 31572Q808 8,327 312,687 SH   SOLE   312,687 0 0
FRESHPET INC COM 358039105 82,539 506,500 SH   SOLE   506,500 0 0
FS DEVELOPMENT CORP II COM CL A 30318F100 2,089 209,332 SH   SOLE   209,332 0 0
F-STAR THERAPEUTICS INC COM 30315R107 9,056 1,054,232 SH   SOLE   1,054,232 0 0
FUSION PHARMACEUTICALS INC COM 36118A100 7,662 948,327 SH   SOLE   948,327 0 0
GALAPAGOS NV SPON ADR 36315X101 11,367 165,000 SH   SOLE   165,000 0 0
GALERA THERAPEUTICS INC COM 36338D108 5,586 568,252 SH   SOLE   568,252 0 0
GAMIDA CELL LTD SHS M47364100 13,506 2,107,000 SH   SOLE   2,107,000 0 0
GOSSAMER BIO INC NOTE 5.000% 6/0 38341PAA0 12,585 15,573,000 PRN   SOLE   15,573,000 0 0
GRAPHITE BIO INC COM 38870X104 66,123 2,151,738 SH   SOLE   2,151,738 0 0
GUARDANT HEALTH INC COM 40131M109 24,838 200,000 SH   SOLE   200,000 0 0
HCA HEALTHCARE INC COM 40412C101 93,033 450,000 SH   SOLE   450,000 0 0
HEALTH CATALYST INC COM 42225T107 43,575 785,000 SH   SOLE   785,000 0 0
HELIX ACQUISITION CORP COM CL A G4444C102 1,599 154,500 SH   SOLE   154,500 0 0
HORIZON THERAPEUTICS PUB L SHS G46188101 58,525 625,000 SH   SOLE   625,000 0 0
HUMANA INC COM 444859102 133,923 302,500 SH   SOLE   302,500 0 0
IDEXX LABS INC COM 45168D104 113,679 180,000 SH   SOLE   180,000 0 0
IMMUNOCORE HLDGS PLC ADS 45258D105 93,517 2,394,785 SH   SOLE   2,394,785 0 0
INNOVAGE HLDG CORP COM 45784A104 19,232 902,500 SH   SOLE   902,500 0 0
INOZYME PHARMA INC COM 45790W108 14,318 840,272 SH   SOLE   840,272 0 0
INSULET CORP COM 45784P101 112,206 408,750 SH   SOLE   408,750 0 0
INTERSECT ENT INC COM 46071F103 20,850 1,220,000 SH   SOLE   1,220,000 0 0
INTUITIVE SURGICAL INC COM NEW 46120E602 110,357 120,000 SH   SOLE   120,000 0 0
INVITAE CORP COM 46185L103 77,648 2,302,032 SH   SOLE   2,302,032 0 0
IRHYTHM TECHNOLOGIES INC COM 450056106 29,725 448,000 SH   SOLE   448,000 0 0
JIYA ACQUISITION CORP COM CL A 47760M102 2,050 206,200 SH   SOLE   206,200 0 0
KARUNA THERAPEUTICS INC COM 48576A100 44,071 386,618 SH   SOLE   386,618 0 0
KINNATE BIOPHARMA INC COM 49705R105 7,719 331,586 SH   SOLE   331,586 0 0
KURA ONCOLOGY INC COM 50127T109 17,030 816,800 SH   SOLE   816,800 0 0
KYMERA THERAPEUTICS INC COM 501575104 30,387 626,527 SH   SOLE   626,527 0 0
LEGEND BIOTECH CORP SPONSORED ADS 52490G102 12,833 312,618 SH   SOLE   312,618 0 0
LIFESTANCE HEALTH GROUP INC COM 53228F101 41,790 1,500,000 SH   SOLE   1,500,000 0 0
MACROGENICS INC COM 556099109 12,243 455,816 SH   SOLE   455,816 0 0
MADRIGAL PHARMACEUTICALS INC COM 558868105 25,570 262,500 SH   SOLE   262,500 0 0
MEREO BIOPHARMA GROUP PLC ADS 589492107 14,401 4,542,769 SH   SOLE   4,542,769 0 0
MERSANA THERAPEUTICS INC COM 59045L106 38,643 2,845,618 SH   SOLE   2,845,618 0 0
MIRATI THERAPEUTICS INC COM 60468T105 51,542 319,085 SH   SOLE   319,085 0 0
MIRUM PHARMACEUTICALS INC COM 604749101 26,345 1,523,723 SH   SOLE   1,523,723 0 0
NEUROCRINE BIOSCIENCES INC COM 64125C109 98,780 1,015,000 SH   SOLE   1,015,000 0 0
NEUROCRINE BIOSCIENCES INC NOTE 2.250% 5/1 64125CAD1 1,347 1,000,000 PRN   SOLE   1,000,000 0 0
NEVRO CORP COM 64157F103 88,034 531,000 SH   SOLE   531,000 0 0
NEVRO CORP NOTE 2.750% 4/0 64157FAC7 866 500,000 PRN   SOLE   500,000 0 0
NKARTA INC COM 65487U108 15,780 497,948 SH   SOLE   497,948 0 0
NOVAVAX INC COM NEW 670002401 96,601 455,000 SH   SOLE   455,000 0 0
NOVOCURE LTD ORD SHS G6674U108 38,819 175,000 SH   SOLE   175,000 0 0
NURIX THERAPEUTICS INC COM 67080M103 8,366 315,350 SH   SOLE   315,350 0 0
NUVATION BIO INC *W EXP 07/07/202 67080N119 348 134,028 SH   SOLE   134,028 0 0
NUVATION BIO INC COM CL A 67080N101 2,248 241,485 SH   SOLE   241,485 0 0
OAK STR HEALTH INC COM 67181A107 21,964 375,000 SH   SOLE   375,000 0 0
OLINK HLDG AB SPONSORED ADS 680710100 14,629 425,000 SH   SOLE   425,000 0 0
ORION ACQUISITION CORP UNIT 02/19/2026 68626A207 9,920 1,000,000 SH   SOLE   1,000,000 0 0
PACIRA BIOSCIENCES INC COM 695127100 62,197 1,025,000 SH   SOLE   1,025,000 0 0
PACIRA BIOSCIENCES INC NOTE 2.375% 4/0 695127AD2 1,094 1,000,000 PRN   SOLE   1,000,000 0 0
PARATEK PHARMACEUTICALS INC COM 699374302 11,285 1,654,714 SH   SOLE   1,654,714 0 0
PENUMBRA INC COM 70975L107 40,424 147,500 SH   SOLE   147,500 0 0
PHASEBIO PHARMACEUTICALS INC COM 717224109 6,859 1,843,764 SH   SOLE   1,843,764 0 0
PHREESIA INC COM 71944F106 58,848 960,000 SH   SOLE   960,000 0 0
POPULATION HEALTH INVS CO IN UNIT 99/99/9999 G71716123 2,041 201,044 SH   SOLE   201,044 0 0
POSEIDA THERAPEUTICS INC COM 73730P108 2,903 289,754 SH   SOLE   289,754 0 0
PPD INC COM 69355F102 31,111 675,000 SH   SOLE   675,000 0 0
PRELUDE THERAPEUTICS INC COM 74065P101 10,947 382,359 SH   SOLE   382,359 0 0
PROMETHEUS BIOSCIENCES INC COM 74349U108 14,640 596,096 SH   SOLE   596,096 0 0
PROTARA THERAPEUTICS INC COM STK 74365U107 6,755 693,542 SH   SOLE   693,542 0 0
PROTHENA CORP PLC SHS G72800108 48,844 950,091 SH   SOLE   950,091 0 0
PULMONX CORP COM 745848101 26,141 592,500 SH   SOLE   592,500 0 0
RADIUS HEALTH INC NOTE 3.000% 9/0 750469AA6 1,393 1,500,000 PRN   SOLE   1,500,000 0 0
RELAY THERAPEUTICS INC COM 75943R102 16,475 450,258 SH   SOLE   450,258 0 0
RENEO PHARMACEUTICALS INC COM 75974E103 10,534 1,129,024 SH   SOLE   1,129,024 0 0
RETROPHIN INC NOTE 2.500% 9/1 761299AB2 2,765 3,250,000 PRN   SOLE   3,250,000 0 0
RHYTHM PHARMACEUTICALS INC COM 76243J105 11,871 606,280 SH   SOLE   606,280 0 0
RIGEL PHARMACEUTICALS INC COM NEW 766559603 20,636 4,754,900 SH   SOLE   4,754,900 0 0
ROCKET PHARMACEUTICALS INC COM 77313F106 17,861 403,270 SH   SOLE   403,270 0 0
SAREPTA THERAPEUTICS INC COM 803607100 25,557 328,750 SH   SOLE   328,750 0 0
SEAGEN INC COM 81181C104 39,470 250,000 SH   SOLE   250,000 0 0
SHATTUCK LABS INC COM 82024L103 9,088 313,499 SH   SOLE   313,499 0 0
SHOCKWAVE MED INC COM 82489T104 41,741 220,000 SH   SOLE   220,000 0 0
SIERRA ONCOLOGY INC COM NEW 82640U404 19,833 1,018,658 SH   SOLE   1,018,658 0 0
SPERO THERAPEUTICS INC COM 84833T103 13,484 965,928 SH   SOLE   965,928 0 0
SPRUCE BIOSCIENCES INC COM 85209E109 17,992 1,605,001 SH   SOLE   1,605,001 0 0
TELEFLEX INCORPORATED COM 879369106 52,233 130,000 SH   SOLE   130,000 0 0
TEMPEST THERAPEUTICS INC COM 87978U108 3,468 310,161 SH   SOLE   310,161 0 0
THERAVANCE BIOPHARMA INC COM G8807B106 9,983 687,500 SH   SOLE   687,500 0 0
THERAVANCE BIOPHARMA INC NOTE 3.250%11/0 88339KAA0 1,429 1,500,000 PRN   SOLE   1,500,000 0 0
TRANSLATE BIO INC COM 89374L104 19,093 693,266 SH   SOLE   693,266 0 0
TRAVERE THERAPEUTICS INC COM 89422G107 21,800 1,494,164 SH   SOLE   1,494,164 0 0
TRILLIUM THERAPEUTICS INC COM NEW 89620X506 6,096 628,500 SH   SOLE   628,500 0 0
TURMERIC ACQUISITION CORP UNIT 10/08/2025 G9127T116 2,072 206,000 SH   SOLE   206,000 0 0
ULTRAGENYX PHARMACEUTICAL IN COM 90400D108 44,338 465,000 SH   SOLE   465,000 0 0
UNITEDHEALTH GROUP INC COM 91324P102 96,106 240,000 SH   SOLE   240,000 0 0
VERVE THERAPEUTICS INC COM 92539P101 58,011 962,826 SH   SOLE   962,826 0 0
WEST PHARMACEUTICAL SVSC INC COM 955306105 10,234 28,500 SH   SOLE   28,500 0 0
XENON PHARMACEUTICALS INC COM 98420N105 10,660 572,500 SH   SOLE   572,500 0 0
ZAI LAB LTD ADR 98887Q104 179,468 1,014,000 SH   SOLE   1,014,000 0 0