The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
10X Genomics Inc Class A CL A COM 88025U109 291,013 1,998,987 SH   DFND 1 1,998,987 0 0
10X Genomics Inc Class A CL A COM 88025U109 276,503 1,899,319 SH   DFND 2 1,773,216 0 126,103
10X Genomics Inc Class A CL A COM 88025U109 128,988 886,028 SH   DFND 3 732,398 0 153,630
10X Genomics Inc Class A CL A COM 88025U109 110,392 758,291 SH   SOLE 0 758,291 0 0
1Life Healthcare COM 68269G107 9 445 SH   DFND 3 445 0 0
2U COM 90214J101 11 319 SH   DFND 3 319 0 0
8x8 Inc COM 282914100 51 2,193 SH   DFND 3 2,193 0 0
908 Devices COM 65443P102 8 249 SH   DFND 3 249 0 0
ACM Research COM 00108J109 24 220 SH   DFND 3 220 0 0
AJ Gallagher & Co COM 363576109 165,016 1,110,096 SH   DFND 1 1,110,096 0 0
AJ Gallagher & Co COM 363576109 541,025 3,639,589 SH   DFND 2 3,404,706 0 234,883
AJ Gallagher & Co COM 363576109 103,283 694,806 SH   DFND 3 326,869 0 367,937
AJ Gallagher & Co COM 363576109 391,401 2,633,038 SH   SOLE 0 2,315,410 0 317,628
Abcellera Biologics Inc COM 00288U106 27,437 1,369,135 SH   DFND 1 1,369,135 0 0
Abcellera Biologics Inc COM 00288U106 8,397 419,028 SH   DFND 2 161,279 0 257,749
Abcellera Biologics Inc COM 00288U106 26,337 1,314,213 SH   DFND 3 1,022,734 0 291,479
Abcellera Biologics Inc COM 00288U106 2,769 138,167 SH   SOLE 0 138,167 0 0
Abiomed COM 003654100 366,318 1,125,332 SH   DFND 1 1,125,332 0 0
Abiomed COM 003654100 506,609 1,556,308 SH   DFND 2 1,437,607 0 118,701
Abiomed COM 003654100 154,098 473,391 SH   DFND 3 345,793 0 127,598
Abiomed COM 003654100 188,372 578,679 SH   SOLE 0 525,595 0 53,084
Acadia Pharmaceuticals Inc COM 004225108 9 544 SH   DFND 3 544 0 0
Accelerate Diagnostics COM 00430H102 2 418 SH   DFND 3 418 0 0
Accenture 'A' COM G1151C101 15 48 SH   DFND 3 48 0 0
Acutus Medical COM 005111109 4 424 SH   DFND 3 424 0 0
Adaptimmune Therapeutics ADR SPONDS ADR 00653A107 26,713 5,166,864 SH   DFND 1 5,166,864 0 0
Adaptimmune Therapeutics ADR SPONDS ADR 00653A107 16,015 3,097,654 SH   DFND 2 1,008,402 0 2,089,252
Adaptimmune Therapeutics ADR SPONDS ADR 00653A107 6,615 1,279,483 SH   DFND 3 1,279,483 0 0
Adaptimmune Therapeutics ADR SPONDS ADR 00653A107 16,963 3,280,979 SH   SOLE 0 3,280,979 0 0
Adicet Bio Inc COM 007002108 733 93,449 SH   DFND 1 93,449 0 0
Adicet Bio Inc COM 007002108 691 88,177 SH   SOLE 0 88,177 0 0
Advanced Micro Devices Inc COM 007903107 44 428 SH   DFND 3 428 0 0
Aerovironment COM 008073108 30,257 350,517 SH   DFND 1 350,517 0 0
Aerovironment COM 008073108 20,491 237,385 SH   DFND 2 77,641 0 159,744
Aerovironment COM 008073108 8,617 99,827 SH   DFND 3 99,827 0 0
Aerovironment COM 008073108 19,039 220,567 SH   SOLE 0 220,567 0 0
Affirm Holdings Inc Class A COM CL A 00827B106 255,322 2,143,220 SH   DFND 1 2,143,220 0 0
Affirm Holdings Inc Class A COM CL A 00827B106 333,117 2,796,247 SH   DFND 2 2,707,833 0 88,414
Affirm Holdings Inc Class A COM CL A 00827B106 22,004 184,704 SH   DFND 3 166,746 0 17,958
Affirm Holdings Inc Class A COM CL A 00827B106 303,514 2,547,756 SH   SOLE 0 2,547,756 0 0
Affirm Holdings Inc Class A - converted at IPO COM CL A 00827B106 74,732 627,313 SH   SOLE 0 627,313 0 0
Affirm Holdings Inc Class B - converted at IPO COM CL A 00827B106 295,987 2,484,575 SH   SOLE 0 2,484,575 0 0
Agios Pharmaceuticals Inc COM 00847X104 9 186 SH   DFND 3 186 0 0
Agora Inc ADR ADS 00851L103 14,189 489,288 SH   DFND 1 489,288 0 0
Agora Inc ADR ADS 00851L103 7,395 255,012 SH   SOLE 0 255,012 0 0
Albemarle Corp COM 012653101 153,041 698,911 SH   DFND 1 698,911 0 0
Albemarle Corp COM 012653101 450,425 2,057,019 SH   DFND 2 1,920,728 0 136,291
Albemarle Corp COM 012653101 76,069 347,394 SH   DFND 3 192,855 0 154,539
Albemarle Corp COM 012653101 322,691 1,473,676 SH   SOLE 0 1,287,511 0 186,165
Alector Inc COM 014442107 1,372 60,132 SH   DFND 1 60,132 0 0
Alector Inc COM 014442107 2,904 127,253 SH   DFND 2 127,253 0 0
Alector Inc COM 014442107 3,491 152,967 SH   DFND 3 152,967 0 0
Alibaba Group Holding Sponsored ADR SPONSORED ADS 01609W102 147,473 996,101 SH   DFND 1 996,101 0 0
Alibaba Group Holding Sponsored ADR SPONSORED ADS 01609W102 636,146 4,296,834 SH   DFND 2 3,563,389 0 733,445
Alibaba Group Holding Sponsored ADR SPONSORED ADS 01609W102 84,861 573,193 SH   DFND 3 243,554 0 329,639
Alibaba Group Holding Sponsored ADR SPONSORED ADS 01609W102 608,657 4,111,160 SH   SOLE 0 3,876,296 0 234,864
Align Technology Inc COM 016255101 16,390 24,631 SH   DFND 2 24,631 0 0
Alkermes Plc COM G01767105 6 192 SH   DFND 3 192 0 0
Allscripts Healthcare Solution COM 01988P108 10 744 SH   DFND 3 744 0 0
Alnylam Pharmaceuticals COM 02043Q107 530,522 2,809,819 SH   DFND 1 2,809,819 0 0
Alnylam Pharmaceuticals COM 02043Q107 773,539 4,096,915 SH   DFND 2 3,449,474 0 647,441
Alnylam Pharmaceuticals COM 02043Q107 254,196 1,346,307 SH   DFND 3 1,007,651 0 338,656
Alnylam Pharmaceuticals COM 02043Q107 408,348 2,162,743 SH   SOLE 0 1,972,180 0 190,563
Alphabet Inc Class A CAP STK CL A 02079K305 12,472 4,665 SH   DFND 1 4,665 0 0
Alphabet Inc Class A CAP STK CL A 02079K305 34,643 12,958 SH   DFND 2 12,958 0 0
Alphabet Inc Class A CAP STK CL A 02079K305 5,705 2,134 SH   DFND 3 1,456 0 678
Alphabet Inc Class A CAP STK CL A 02079K305 99,220 37,112 SH   SOLE 0 37,112 0 0
Alphabet Inc Class C CAP STK CL C 02079K107 236,783 88,839 SH   DFND 1 88,839 0 0
Alphabet Inc Class C CAP STK CL C 02079K107 885,480 332,224 SH   DFND 2 311,173 0 21,051
Alphabet Inc Class C CAP STK CL C 02079K107 167,421 62,815 SH   DFND 3 29,589 0 33,226
Alphabet Inc Class C CAP STK CL C 02079K107 513,744 192,752 SH   SOLE 0 164,422 0 28,330
Alteryx Inc COM 02156B103 25 336 SH   DFND 3 336 0 0
Amazon.Com COM 023135106 1,038,007 315,980 SH   DFND 1 315,980 0 0
Amazon.Com COM 023135106 3,884,116 1,182,365 SH   DFND 2 675,699 0 506,666
Amazon.Com COM 023135106 470,789 143,313 SH   DFND 3 106,607 0 36,706
Amazon.Com COM 023135106 1,982,256 603,419 SH   SOLE 0 483,757 0 119,662
Ambarella SHS G037AX101 45,351 291,200 SH   DFND 1 291,200 0 0
Ambarella SHS G037AX101 20,198 129,692 SH   DFND 2 41,693 0 87,999
Ambarella SHS G037AX101 8,133 52,222 SH   DFND 3 52,222 0 0
Ambarella SHS G037AX101 15,201 97,605 SH   SOLE 0 97,605 0 0
Amdocs COM G02602103 28 365 SH   DFND 3 365 0 0
Ameren COM 023608102 43,820 540,982 SH   DFND 1 540,982 0 0
Ameren COM 023608102 98 1,204 SH   DFND 2 1,204 0 0
Ameren COM 023608102 2,549 31,463 SH   DFND 3 31,463 0 0
American Electric Power COM 025537101 47,449 584,496 SH   DFND 1 584,496 0 0
American Electric Power COM 025537101 98 1,202 SH   DFND 2 1,202 0 0
American Electric Power COM 025537101 2,733 33,666 SH   DFND 3 33,666 0 0
American Superconductor Corp COM 030111207 10,547 723,370 SH   DFND 1 723,370 0 0
American Superconductor Corp COM 030111207 11,197 768,000 SH   SOLE 0 768,000 0 0
American Tower Corp REIT COM 03027X100 512 1,930 SH   DFND 1 1,930 0 0
American Well Corp Class A COM 03044L105 820 90,028 SH   DFND 1 90,028 0 0
American Well Corp Class A COM 03044L105 1,732 190,084 SH   DFND 2 190,084 0 0
American Well Corp Class A COM 03044L105 2,026 222,439 SH   DFND 3 222,439 0 0
Amicus Therapeutics Inc COM 03152W109 5 538 SH   DFND 3 538 0 0
Amkor Technology COM 031652100 47 1,891 SH   DFND 3 1,891 0 0
Amneal Pharmaceuticals Inc COM 03168L105 2 452 SH   DFND 3 452 0 0
Analog Devices COM 032654105 29,731 177,522 SH   DFND 1 177,522 0 0
Analog Devices COM 032654105 630 3,763 SH   DFND 2 0 0 3,763
Analog Devices COM 032654105 525 3,135 SH   DFND 3 3,135 0 0
Analog Devices COM 032654105 28,403 169,590 SH   SOLE 0 169,590 0 0
Anaplan Inc Common COM 03272L108 19 306 SH   DFND 3 306 0 0
Anterix COM 03676C100 10 162 SH   DFND 3 162 0 0
Anthem Inc COM 036752103 185,464 497,488 SH   DFND 1 497,488 0 0
Anthem Inc COM 036752103 682,953 1,831,955 SH   DFND 2 1,711,096 0 120,859
Anthem Inc COM 036752103 133,371 357,754 SH   DFND 3 168,087 0 189,667
Anthem Inc COM 036752103 487,423 1,307,466 SH   SOLE 0 1,144,364 0 163,102
AppFolio COM 03783C100 29 241 SH   DFND 3 241 0 0
Appian Corp CL A 03782L101 206,849 2,235,963 SH   DFND 1 2,235,963 0 0
Appian Corp CL A 03782L101 252,718 2,731,787 SH   DFND 2 2,351,166 0 380,621
Appian Corp CL A 03782L101 27,341 295,544 SH   DFND 3 295,544 0 0
Appian Corp CL A 03782L101 82,628 893,176 SH   SOLE 0 893,176 0 0
Apple COM 037833100 30,161 213,152 SH   DFND 1 213,152 0 0
Apple COM 037833100 648 4,579 SH   DFND 2 0 0 4,579
Apple COM 037833100 540 3,816 SH   DFND 3 3,816 0 0
Apple COM 037833100 29,182 206,235 SH   SOLE 0 206,235 0 0
Aptiv COM G6095L109 20 134 SH   DFND 3 134 0 0
Ares Capital Corp COM 04010L103 102,410 5,037,400 SH   DFND 1 5,037,400 0 0
Ares Capital Corp COM 04010L103 218 10,700 SH   DFND 2 10,700 0 0
Ares Capital Corp COM 04010L103 5,901 290,270 SH   DFND 3 290,270 0 0
Argan COM 04010E109 4 103 SH   DFND 3 103 0 0
Ascendis Pharma ADR 1:1 SPON ADR 04351P101 2,307 14,474 SH   DFND 1 14,474 0 0
Ascendis Pharma ADR 1:1 SPON ADR 04351P101 5,010 31,431 SH   DFND 2 31,431 0 0
Ascendis Pharma ADR 1:1 SPON ADR 04351P101 5,982 37,529 SH   DFND 3 37,529 0 0
Asensus Surgical Inc COM 04367G103 10 5,338 SH   DFND 3 5,338 0 0
AstraZeneca ADR COM 046353108 24 400 SH   DFND 3 400 0 0
Atlassian Corp Plc CL A G06242104 197,624 504,889 SH   DFND 1 504,889 0 0
Atlassian Corp Plc CL A G06242104 1,521,590 3,887,358 SH   DFND 2 1,227,129 0 2,660,229
Atlassian Corp Plc CL A G06242104 180,789 461,879 SH   DFND 3 385,269 0 76,610
Atlassian Corp Plc CL A G06242104 406,460 1,038,423 SH   SOLE 0 480,916 0 557,507
Atrion COM 049904105 6 9 SH   DFND 3 9 0 0
Autohome Inc - ADR SP ADR RP CL A 05278C107 17,513 373,164 SH   DFND 1 373,164 0 0
Autohome Inc - ADR SP ADR RP CL A 05278C107 63,311 1,349,058 SH   DFND 2 1,256,642 0 92,416
Autohome Inc - ADR SP ADR RP CL A 05278C107 12,502 266,392 SH   DFND 3 121,668 0 144,724
Autohome Inc - ADR SP ADR RP CL A 05278C107 46,525 991,370 SH   SOLE 0 869,280 0 122,090
Avangrid COM 05351W103 70,303 1,446,574 SH   DFND 1 1,446,574 0 0
Avangrid COM 05351W103 137 2,828 SH   DFND 2 2,828 0 0
Avangrid COM 05351W103 3,655 75,212 SH   DFND 3 75,212 0 0
Avery Dennison Corporation COM 053611109 23 110 SH   DFND 3 110 0 0
Axogen Inc COM 05463X106 6,950 439,900 SH   DFND 1 439,900 0 0
Axogen Inc COM 05463X106 6,021 381,062 SH   DFND 2 126,487 0 254,575
Axogen Inc COM 05463X106 2,703 171,097 SH   DFND 3 171,097 0 0
Axogen Inc COM 05463X106 2,680 169,600 SH   SOLE 0 169,600 0 0
Axon Enterprise Inc COM 05464C101 143,463 819,697 SH   DFND 1 819,697 0 0
Axon Enterprise Inc COM 05464C101 329,013 1,879,860 SH   DFND 2 1,620,398 0 259,462
Axon Enterprise Inc COM 05464C101 76,211 435,444 SH   DFND 3 257,342 0 178,102
Axon Enterprise Inc COM 05464C101 245,668 1,403,657 SH   SOLE 0 1,245,932 0 157,725
Axonics Modulation Technologies COM 05465P101 15 230 SH   DFND 3 230 0 0
Baidu.com Sponsored ADR SPON ADR REP A 056752108 11,380 74,017 SH   DFND 1 74,017 0 0
Baidu.com Sponsored ADR SPON ADR REP A 056752108 548,921 3,570,217 SH   DFND 2 3,260,235 0 309,982
Baidu.com Sponsored ADR SPON ADR REP A 056752108 29,332 190,779 SH   DFND 3 28,799 0 161,980
Baidu.com Sponsored ADR SPON ADR REP A 056752108 1,094 7,113 SH   DFND 4 7,113 0 0
Baidu.com Sponsored ADR SPON ADR REP A 056752108 77 498 SH   SOLE 0 498 0 0
Banco Bradesco Pn ADR SP ADR PFD NEW 059460303 16,821 4,391,881 SH   DFND 1 4,391,881 0 0
Banco Bradesco Pn ADR SP ADR PFD NEW 059460303 130,950 34,190,491 SH   DFND 2 18,902,188 0 15,288,303
Banco Bradesco Pn ADR SP ADR PFD NEW 059460303 6,455 1,685,300 SH   DFND 3 1,685,300 0 0
Bandwidth COM 05988J103 26 287 SH   DFND 2 287 0 0
Bandwidth COM 05988J103 15 161 SH   DFND 3 161 0 0
Baozun Spn Adr 1:1 SPONSORED ADR 06684L103 10,385 592,408 SH   DFND 1 592,408 0 0
Baozun Spn Adr 1:1 SPONSORED ADR 06684L103 7,522 429,093 SH   DFND 2 138,898 0 290,195
Baozun Spn Adr 1:1 SPONSORED ADR 06684L103 3,256 185,739 SH   DFND 3 185,739 0 0
Baozun Spn Adr 1:1 SPONSORED ADR 06684L103 5,156 294,100 SH   SOLE 0 294,100 0 0
Beam Therapeutics COM 07373V105 37 425 SH   DFND 3 425 0 0
Beam Therapeutics COM 07373V105 894 10,275 SH   SOLE 0 10,275 0 0
BeiGene Ltd SPONSORED ADR 07725L102 140,251 386,366 SH   DFND 1 386,366 0 0
BeiGene Ltd SPONSORED ADR 07725L102 1,075,840 2,963,747 SH   DFND 2 1,114,235 0 1,849,512
BeiGene Ltd SPONSORED ADR 07725L102 100,394 276,567 SH   DFND 3 230,286 0 46,281
BeiGene Ltd SPONSORED ADR 07725L102 225,921 622,372 SH   SOLE 0 288,709 0 333,663
Benefitfocus Inc COM 08180D106 3,402 306,448 SH   DFND 1 306,448 0 0
Benefitfocus Inc COM 08180D106 3,215 289,682 SH   DFND 2 82,001 0 207,681
Benefitfocus Inc COM 08180D106 1,309 117,894 SH   DFND 3 117,894 0 0
Benefitfocus Inc COM 08180D106 2,513 226,368 SH   SOLE 0 226,368 0 0
Berkeley Lights Inc COM 084310101 23,857 1,219,671 SH   DFND 1 1,219,671 0 0
Berkeley Lights Inc COM 084310101 8,295 424,061 SH   DFND 2 275,795 0 148,266
Berkeley Lights Inc COM 084310101 18,887 965,612 SH   DFND 3 796,400 0 169,212
Berkeley Lights Inc COM 084310101 6,390 326,690 SH   SOLE 0 326,690 0 0
Beyond Meat Inc COM 08862E109 127,589 1,212,132 SH   DFND 1 1,212,132 0 0
Beyond Meat Inc COM 08862E109 515,156 4,894,133 SH   DFND 2 1,552,309 0 3,341,824
Beyond Meat Inc COM 08862E109 119,761 1,137,767 SH   DFND 3 917,901 0 219,866
Beyond Meat Inc COM 08862E109 138,442 1,315,239 SH   SOLE 0 639,668 0 675,571
Bilibili Inc ADR SPONSORED ADR 090040106 26,199 395,941 SH   DFND 1 395,941 0 0
Bilibili Inc ADR SPONSORED ADR 090040106 28,762 434,662 SH   DFND 2 246,135 0 188,527
Bilibili Inc ADR SPONSORED ADR 090040106 2,046 30,913 SH   DFND 3 0 0 30,913
Bilibili Inc ADR SPONSORED ADR 090040106 6,538 98,800 SH   SOLE 0 41,921 0 56,879
BioCryst Pharmaceuticals COM 09058V103 22 1,500 SH   DFND 3 1,500 0 0
BioNTech ADR SPONS ADS 09075V102 150,038 549,610 SH   DFND 1 549,610 0 0
BioNTech ADR SPONS ADS 09075V102 1,151,003 4,216,281 SH   DFND 2 1,330,142 0 2,886,139
BioNTech ADR SPONS ADS 09075V102 123,709 453,162 SH   DFND 3 388,406 0 64,756
BioNTech ADR SPONS ADS 09075V102 307,458 1,126,260 SH   SOLE 0 522,512 0 603,748
Biomarin Pharmaceutical Inc COM 09061G101 6 82 SH   DFND 3 82 0 0
Blackline COM 09239B109 71,656 606,942 SH   DFND 1 606,942 0 0
Blackline COM 09239B109 39,057 330,826 SH   DFND 2 108,252 0 222,574
Blackline COM 09239B109 16,417 139,059 SH   DFND 3 139,059 0 0
Blackline COM 09239B109 33,125 280,576 SH   SOLE 0 280,576 0 0
Blackrock Inc COM 09247X101 18 21 SH   DFND 3 21 0 0
Blink Charging COM 09354A100 11 400 SH   DFND 3 400 0 0
Blue Apron Holdings Inc CL A 09523Q101 1,092 148,506 SH   DFND 1 148,506 0 0
Bluebird Bio Inc COM 09609G100 16 860 SH   DFND 3 860 0 0
Blueprint Medicines Corp COM 09627Y109 35 343 SH   DFND 3 343 0 0
Booking Holdings Inc COM 09857L108 117,113 49,334 SH   DFND 1 49,334 0 0
Booking Holdings Inc COM 09857L108 358,295 150,933 SH   DFND 2 140,850 0 10,083
Booking Holdings Inc COM 09857L108 73,345 30,897 SH   DFND 3 14,793 0 16,104
Booking Holdings Inc COM 09857L108 267,281 112,593 SH   SOLE 0 98,516 0 14,077
Boston Omaha COM 101044105 21 529 SH   DFND 3 529 0 0
Box Inc COM 10316T104 23 979 SH   DFND 3 979 0 0
Brady Corp COM 104674106 12 245 SH   DFND 3 245 0 0
BridgeBio Pharma Inc COM 10806X102 3,767 80,367 SH   DFND 1 80,367 0 0
BridgeBio Pharma Inc COM 10806X102 8,425 179,760 SH   DFND 2 179,760 0 0
BridgeBio Pharma Inc COM 10806X102 9,643 205,749 SH   DFND 3 205,749 0 0
Bristol Myers Squibb COM 110122108 28 474 SH   DFND 3 474 0 0
British Amer.Tobacco - ADR SPONSORED ADR 110448107 3,356 95,121 SH   DFND 1 95,121 0 0
British Amer.Tobacco - ADR SPONSORED ADR 110448107 53 1,493 SH   DFND 3 1,493 0 0
British Amer.Tobacco - ADR SPONSORED ADR 110448107 3,440 97,492 SH   SOLE 0 97,492 0 0
Broadridge Finl.Sltn. COM 11133T103 83,287 499,801 SH   DFND 1 499,801 0 0
Broadridge Finl.Sltn. COM 11133T103 319,912 1,919,777 SH   DFND 2 1,799,689 0 120,088
Broadridge Finl.Sltn. COM 11133T103 59,892 359,408 SH   DFND 3 170,818 0 188,590
Broadridge Finl.Sltn. COM 11133T103 217,252 1,303,720 SH   SOLE 0 1,144,135 0 159,585
Brookfield Renewable COM 11284V105 40,637 1,047,076 SH   DFND 1 1,047,076 0 0
Brookfield Renewable COM 11284V105 126 3,252 SH   DFND 2 3,252 0 0
Brookfield Renewable COM 11284V105 3,213 82,792 SH   DFND 3 82,792 0 0
Bumble Inc COM CL A 12047B105 19,992 400,000 SH   SOLE 0 400,000 0 0
Burford Capital ORD SHS G17977110 11,338 1,038,109 SH   DFND 1 1,038,109 0 0
Burning Rock Biotech Ltd ADR SPON ADS 12233L107 36,668 2,050,783 SH   DFND 1 2,050,783 0 0
Burning Rock Biotech Ltd ADR SPON ADS 12233L107 114,325 6,394,005 SH   DFND 2 4,718,690 0 1,675,315
Burning Rock Biotech Ltd ADR SPON ADS 12233L107 3,855 215,592 SH   DFND 3 37,880 0 177,712
Burning Rock Biotech Ltd ADR SPON ADS 12233L107 2,356 131,772 SH   SOLE 0 131,772 0 0
Butterfly Network Inc COM CL A 124155102 2,451 234,811 SH   DFND 1 234,811 0 0
Butterfly Network Inc COM CL A 124155102 3,743 358,547 SH   DFND 2 358,547 0 0
Butterfly Network Inc COM CL A 124155102 6,363 609,500 SH   DFND 3 609,500 0 0
Butterfly Network Inc COM CL A 124155102 8,479 812,150 SH   SOLE 0 812,150 0 0
C3.ai CL A 12468P104 5 117 SH   DFND 3 117 0 0
CEVA Inc COM 157210105 7,624 178,680 SH   DFND 1 178,680 0 0
CEVA Inc COM 157210105 6,611 154,930 SH   DFND 2 49,409 0 105,521
CEVA Inc COM 157210105 2,703 63,354 SH   DFND 3 63,354 0 0
CEVA Inc COM 157210105 3,520 82,500 SH   SOLE 0 82,500 0 0
CH Robinson Worldwide COM NEW 12541W209 26,136 300,409 SH   DFND 1 300,409 0 0
CH Robinson Worldwide COM NEW 12541W209 560 6,439 SH   DFND 2 0 0 6,439
CH Robinson Worldwide COM NEW 12541W209 465 5,341 SH   DFND 3 5,341 0 0
CH Robinson Worldwide COM NEW 12541W209 25,156 289,151 SH   SOLE 0 289,151 0 0
CS Disco Inc COM 126327105 24 504 SH   DFND 2 504 0 0
Calavo Growers Inc COM 128246105 4 113 SH   DFND 3 113 0 0
Cardlytics Inc COM 14161W105 21,721 258,770 SH   DFND 1 258,770 0 0
Cardlytics Inc COM 14161W105 18,060 215,151 SH   DFND 2 70,197 0 144,954
Cardlytics Inc COM 14161W105 7,451 88,771 SH   DFND 3 88,771 0 0
Cardlytics Inc COM 14161W105 15,370 183,112 SH   SOLE 0 183,112 0 0
Cargurus Inc COM 141788109 24 759 SH   DFND 2 759 0 0
Cargurus Inc COM 141788109 14 431 SH   DFND 3 431 0 0
Carvana COM 146869102 395,559 1,311,795 SH   DFND 1 1,311,795 0 0
Carvana COM 146869102 1,160,156 3,847,435 SH   DFND 2 2,426,562 0 1,420,873
Carvana COM 146869102 126,532 419,618 SH   DFND 3 307,086 0 112,532
Carvana COM 146869102 645,053 2,139,195 SH   SOLE 0 1,796,387 0 342,808
Castle Biosciences COM 14843C105 15 225 SH   DFND 3 225 0 0
Cbre Group Inc CL A 12504L109 155,042 1,592,457 SH   DFND 1 1,592,457 0 0
Cbre Group Inc CL A 12504L109 489,639 5,029,156 SH   DFND 2 4,710,103 0 319,053
Cbre Group Inc CL A 12504L109 93,946 964,932 SH   DFND 3 462,032 0 502,900
Cbre Group Inc CL A 12504L109 344,142 3,534,736 SH   SOLE 0 3,100,032 0 434,704
Cellectis ADR SPONS ADS 15117K103 9,162 726,605 SH   DFND 1 726,605 0 0
Cellectis ADR SPONS ADS 15117K103 2,136 169,420 SH   DFND 2 169,420 0 0
Cellectis ADR SPONS ADS 15117K103 2,276 180,500 SH   SOLE 0 180,500 0 0
Celsius Holdings COM 15118V207 23 260 SH   DFND 3 260 0 0
Cemex ADR SPON ADR NEW 151290889 37,680 5,255,166 SH   DFND 1 5,255,166 0 0
Cemex ADR SPON ADR NEW 151290889 196,704 27,434,341 SH   DFND 2 11,161,053 0 16,273,288
Cemex ADR SPON ADR NEW 151290889 62,111 8,662,679 SH   DFND 3 1,243,286 0 7,419,393
Cemex ADR SPON ADR NEW 151290889 2,538 353,925 SH   DFND 4 353,925 0 0
Certara COM 15687V109 53,773 1,624,567 SH   DFND 1 1,624,567 0 0
Certara COM 15687V109 185,198 5,595,107 SH   DFND 2 4,997,304 0 597,803
Certara COM 15687V109 37,246 1,125,255 SH   DFND 3 535,752 0 589,503
Certara COM 15687V109 142,598 4,308,086 SH   SOLE 0 3,787,903 0 520,183
Cerus COM 157085101 7 1,143 SH   DFND 3 1,143 0 0
ChargePoint Holdings Inc COM CL A 15961R105 127 6,341 SH   DFND 1 6,341 0 0
ChargePoint Holdings Inc COM CL A 15961R105 91,453 4,574,933 SH   SOLE 0 4,574,933 0 0
Chegg COM 163092109 401,305 5,899,810 SH   DFND 1 5,899,810 0 0
Chegg COM 163092109 554,794 8,156,336 SH   DFND 2 7,313,429 0 842,907
Chegg COM 163092109 82,835 1,217,810 SH   DFND 3 911,336 0 306,474
Chegg COM 163092109 219,527 3,227,389 SH   SOLE 0 3,003,148 0 224,241
Chewy Inc CL A 16679L109 203,789 2,992,058 SH   DFND 1 2,992,058 0 0
Chewy Inc CL A 16679L109 274,709 4,033,312 SH   DFND 2 3,901,781 0 131,531
Chewy Inc CL A 16679L109 13,380 196,449 SH   DFND 3 196,449 0 0
Chewy Inc CL A 16679L109 42,597 625,420 SH   SOLE 0 625,420 0 0
Chinook Therapeutics COM 16961L106 5,055 396,187 SH   DFND 1 396,187 0 0
Chinook Therapeutics COM 16961L106 2,857 223,878 SH   DFND 2 77,815 0 146,063
Chinook Therapeutics COM 16961L106 1,282 100,453 SH   DFND 3 100,453 0 0
Chinook Therapeutics COM 16961L106 1,494 117,058 SH   SOLE 0 117,058 0 0
Church & Dwight Co Inc COM 171340102 15 179 SH   DFND 3 179 0 0
Cisco Systems COM 17275R102 18,680 343,198 SH   DFND 1 343,198 0 0
Cisco Systems COM 17275R102 395 7,263 SH   DFND 2 0 0 7,263
Cisco Systems COM 17275R102 334 6,128 SH   DFND 3 6,128 0 0
Cisco Systems COM 17275R102 18,014 330,966 SH   SOLE 0 330,966 0 0
Clear Secure Inc COM 18467V109 41,050 1,000,000 SH   SOLE 0 1,000,000 0 0
Cloudera Inc COM 18914U100 7 428 SH   DFND 3 428 0 0
Cloudflare Inc CL A COM 18915M107 547,825 4,863,068 SH   DFND 1 4,863,068 0 0
Cloudflare Inc CL A COM 18915M107 1,911,862 16,971,699 SH   DFND 2 10,054,741 0 6,916,958
Cloudflare Inc CL A COM 18915M107 215,810 1,915,755 SH   DFND 3 1,461,937 0 453,818
Cloudflare Inc CL A COM 18915M107 674,145 5,984,420 SH   SOLE 0 4,258,381 0 1,726,039
Clover Health Investments Corp COM CL A 18914F103 38,001 5,142,177 SH   SOLE 0 5,142,177 0 0
CoStar Group COM 22160N109 305,782 3,553,124 SH   DFND 1 3,553,124 0 0
CoStar Group COM 22160N109 529,467 6,152,305 SH   DFND 2 5,883,357 0 268,948
CoStar Group COM 22160N109 53,279 619,086 SH   DFND 3 393,388 0 225,698
CoStar Group COM 22160N109 190,405 2,212,465 SH   SOLE 0 2,017,111 0 195,354
Coca Cola COM 191216100 19,191 365,761 SH   DFND 1 365,761 0 0
Coca Cola COM 191216100 560 10,677 SH   DFND 2 0 0 10,677
Coca Cola COM 191216100 382 7,271 SH   DFND 3 7,271 0 0
Coca Cola COM 191216100 25,289 481,962 SH   SOLE 0 481,962 0 0
Codexis COM 192005106 55,005 2,364,796 SH   DFND 1 2,364,796 0 0
Codexis COM 192005106 46,193 1,985,960 SH   DFND 2 744,766 0 1,241,194
Codexis COM 192005106 21,351 917,928 SH   DFND 3 868,361 0 49,567
Codexis COM 192005106 31,404 1,350,139 SH   SOLE 0 1,350,139 0 0
Cognyte Software ORD SHS M25133105 8 369 SH   DFND 3 369 0 0
Cohen & Steers Inc COM 19247A100 27 325 SH   DFND 3 325 0 0
Coherus BioSciences COM 19249H103 26 1,605 SH   DFND 3 1,605 0 0
Cohu COM 192576106 22 700 SH   DFND 3 700 0 0
Columbia Sportswear Co COM 198516106 9 95 SH   DFND 3 95 0 0
Commscope Holding Co Inc COM 20337X109 20 1,442 SH   DFND 3 1,442 0 0
Consolidated Edison COM 209115104 54,001 743,914 SH   DFND 1 743,914 0 0
Consolidated Edison COM 209115104 97 1,335 SH   DFND 2 1,335 0 0
Consolidated Edison COM 209115104 2,621 36,103 SH   DFND 3 36,103 0 0
Cooper Cos Inc/The COM 216648402 12,967 31,373 SH   DFND 2 31,373 0 0
Copa Holdings S A CL A P31076105 33,641 413,383 SH   DFND 1 413,383 0 0
Copa Holdings S A CL A P31076105 281,516 3,459,280 SH   DFND 2 2,278,337 0 1,180,943
Copa Holdings S A CL A P31076105 61,844 759,947 SH   DFND 3 99,749 0 660,198
Copa Holdings S A CL A P31076105 2,288 28,117 SH   DFND 4 28,117 0 0
Cornerstone Ondemand Inc COM 21925Y103 48 838 SH   DFND 3 838 0 0
Costco Wholesale Corporation COM 22160K105 29 65 SH   DFND 3 65 0 0
Coupa Software Inc COM 22266L106 71 324 SH   DFND 3 324 0 0
Coupang CL A 22266T109 113,586 4,078,493 SH   DFND 1 4,078,493 0 0
Coupang CL A 22266T109 938,870 33,711,665 SH   DFND 2 13,247,345 0 20,464,320
Coupang CL A 22266T109 105,888 3,802,078 SH   DFND 3 2,893,503 0 908,575
Coupang CL A 22266T109 517 18,547 SH   DFND 4 18,547 0 0
Coupang CL A 22266T109 206,220 7,404,672 SH   SOLE 0 3,439,204 0 3,965,468
Coursera Inc COM 22266M104 210,393 6,647,502 SH   DFND 1 6,647,502 0 0
Coursera Inc COM 22266M104 207,287 6,549,343 SH   DFND 2 5,947,921 0 601,422
Coursera Inc COM 22266M104 75,849 2,396,489 SH   DFND 3 1,927,615 0 468,874
Coursera Inc COM 22266M104 38,815 1,226,384 SH   SOLE 0 1,226,384 0 0
Credicorp COM G2519Y108 9,967 89,842 SH   DFND 1 89,842 0 0
Credicorp COM G2519Y108 146,239 1,318,185 SH   DFND 2 875,375 0 442,810
Credicorp COM G2519Y108 31,596 284,805 SH   DFND 3 39,086 0 245,719
Credicorp COM G2519Y108 1,349 12,158 SH   DFND 4 12,158 0 0
CrowdStrike Holdings COM 22788C105 31 125 SH   DFND 3 125 0 0
Cullen/Frost Bankers COM 229899109 14,457 121,878 SH   DFND 1 121,878 0 0
Cullen/Frost Bankers COM 229899109 306 2,576 SH   DFND 2 0 0 2,576
Cullen/Frost Bankers COM 229899109 259 2,187 SH   DFND 3 2,187 0 0
Cullen/Frost Bankers COM 229899109 14,125 119,081 SH   SOLE 0 119,081 0 0
CureVac N.V. - Converted at IPO COM N2451R105 91,586 1,676,780 SH   DFND 2 1,676,780 0 0
Curevac N.V. COM N2451R105 123,657 2,263,951 SH   DFND 2 1,803,084 0 460,867
CyberArk Software Ltd SHS M2682V108 40,098 254,077 SH   DFND 1 254,077 0 0
CyberArk Software Ltd SHS M2682V108 33,273 210,829 SH   DFND 2 68,934 0 141,895
CyberArk Software Ltd SHS M2682V108 13,898 88,062 SH   DFND 3 88,062 0 0
CyberArk Software Ltd SHS M2682V108 18,168 115,118 SH   SOLE 0 115,118 0 0
DTE Energy Co COM 233331107 48,151 431,032 SH   DFND 1 431,032 0 0
DTE Energy Co COM 233331107 98 877 SH   DFND 2 877 0 0
DTE Energy Co COM 233331107 2,682 24,012 SH   DFND 3 24,012 0 0
Dada Nexus Ltd ADR ADS 23344D108 59,581 2,973,115 SH   DFND 1 2,973,115 0 0
Dada Nexus Ltd ADR ADS 23344D108 75,313 3,758,131 SH   DFND 2 2,535,800 0 1,222,331
Dada Nexus Ltd ADR ADS 23344D108 1,065 53,141 SH   DFND 3 53,141 0 0
Dada Nexus Ltd ADR ADS 23344D108 15,685 782,705 SH   SOLE 0 782,705 0 0
Darden Restaurants COM 237194105 12 82 SH   DFND 3 82 0 0
Datadog COM 23804L103 229,942 1,626,753 SH   DFND 1 1,626,753 0 0
Datadog COM 23804L103 458,249 3,241,945 SH   DFND 2 3,086,289 0 155,656
Datadog COM 23804L103 55,029 389,313 SH   DFND 3 222,792 0 166,521
Datadog COM 23804L103 199,182 1,409,137 SH   SOLE 0 1,268,282 0 140,855
Deere & Co COM 244199105 143,339 427,789 SH   DFND 1 427,789 0 0
Deere & Co COM 244199105 42,059 125,523 SH   DFND 2 48,201 0 77,322
Deere & Co COM 244199105 135,814 405,331 SH   DFND 3 315,487 0 89,844
Deere & Co COM 244199105 13,727 40,968 SH   SOLE 0 40,968 0 0
Denali Therapeutics COM 24823R105 156,169 3,095,518 SH   DFND 1 3,095,518 0 0
Denali Therapeutics COM 24823R105 211,212 4,186,566 SH   DFND 2 4,058,908 0 127,658
Denali Therapeutics COM 24823R105 22,037 436,801 SH   DFND 3 398,181 0 38,620
Denali Therapeutics COM 24823R105 367,827 7,290,931 SH   SOLE 0 7,290,931 0 0
DermTech COM 24984K105 9 286 SH   DFND 3 286 0 0
Dexcom Inc COM 252131107 419,537 767,175 SH   DFND 1 767,175 0 0
Dexcom Inc COM 252131107 1,655,447 3,027,187 SH   DFND 2 972,959 0 2,054,228
Dexcom Inc COM 252131107 407,341 744,872 SH   DFND 3 606,230 0 138,642
Dexcom Inc COM 252131107 443,276 810,584 SH   SOLE 0 395,920 0 414,664
Digimarc COM 25381B101 9,039 262,445 SH   DFND 1 262,445 0 0
Digimarc COM 25381B101 9,959 289,172 SH   DFND 2 94,299 0 194,873
Digimarc COM 25381B101 4,142 120,256 SH   DFND 3 120,256 0 0
Digimarc COM 25381B101 5,328 154,711 SH   SOLE 0 154,711 0 0
Docebo COM 25609L105 9,867 135,151 SH   DFND 2 135,151 0 0
Docebo COM 25609L105 19 267 SH   DFND 3 267 0 0
Dolby Laboratories 'A' COM 25659T107 13,803 156,851 SH   DFND 1 156,851 0 0
Dolby Laboratories 'A' COM 25659T107 292 3,321 SH   DFND 2 0 0 3,321
Dolby Laboratories 'A' COM 25659T107 245 2,789 SH   DFND 3 2,789 0 0
Dolby Laboratories 'A' COM 25659T107 13,125 149,143 SH   SOLE 0 149,143 0 0
Domo COM 257554105 29 348 SH   DFND 3 348 0 0
Doordash Inc COM 25809K105 276,837 1,344,001 SH   DFND 1 1,344,001 0 0
Doordash Inc COM 25809K105 630,544 3,061,189 SH   DFND 2 2,897,434 0 163,755
Doordash Inc COM 25809K105 90,485 439,292 SH   DFND 3 235,189 0 204,103
Doordash Inc COM 25809K105 522,209 2,535,243 SH   SOLE 0 2,358,511 0 176,732
Dropbox CL A 26210C104 26 881 SH   DFND 3 881 0 0
Dt Midstream Inc COM 23345M107 10,027 216,850 SH   DFND 1 216,850 0 0
Dt Midstream Inc COM 23345M107 20 438 SH   DFND 2 438 0 0
Dt Midstream Inc COM 23345M107 555 12,006 SH   DFND 3 12,006 0 0
Duck Creek Technologies SHS 264120106 16 355 SH   DFND 3 355 0 0
Duke Realty Corporation REIT COM 264411505 64,979 1,357,400 SH   DFND 1 1,357,400 0 0
Duke Realty Corporation REIT COM 264411505 162 3,392 SH   DFND 2 3,392 0 0
Duke Realty Corporation REIT COM 264411505 3,513 73,390 SH   DFND 3 73,390 0 0
Duolingo Inc CL A COM 26603R106 79,653 478,798 SH   DFND 1 478,798 0 0
Duolingo Inc CL A COM 26603R106 107,291 644,932 SH   DFND 2 624,302 0 20,630
Duolingo Inc CL A COM 26603R106 5,226 31,411 SH   DFND 3 31,411 0 0
Duolingo Inc CL A COM 26603R106 18,352 110,316 SH   SOLE 0 110,316 0 0
EHang Hdgs ADR ADS 26853E102 50 2,100 SH   DFND 1 2,100 0 0
Eargo COM 270087109 2 263 SH   DFND 3 263 0 0
Ecolab COM 278865100 75,892 363,781 SH   DFND 1 363,781 0 0
Ecolab COM 278865100 32,673 156,616 SH   DFND 2 90,677 0 65,939
Ecolab COM 278865100 72,422 347,147 SH   DFND 3 270,476 0 76,671
Ecolab COM 278865100 6,689 32,065 SH   SOLE 0 32,065 0 0
Edwards Lifesciences Corp COM 28176E108 5,737 50,676 SH   DFND 1 50,676 0 0
Edwards Lifesciences Corp COM 28176E108 27,164 239,942 SH   DFND 2 239,942 0 0
Edwards Lifesciences Corp COM 28176E108 14,822 130,927 SH   DFND 3 130,927 0 0
Emergent Biosolutions Inc COM 29089Q105 19 385 SH   DFND 3 385 0 0
Enphase Energy Inc COM 29355A107 135 900 SH   DFND 1 900 0 0
Estee Lauder 'A' COM 518439104 112,611 375,458 SH   DFND 1 375,458 0 0
Estee Lauder 'A' COM 518439104 435,568 1,452,232 SH   DFND 2 1,364,378 0 87,854
Estee Lauder 'A' COM 518439104 78,318 261,122 SH   DFND 3 123,556 0 137,566
Estee Lauder 'A' COM 518439104 288,724 962,638 SH   SOLE 0 843,549 0 119,089
EverQuote Inc COM CL A 30041R108 13,394 718,967 SH   DFND 1 718,967 0 0
EverQuote Inc COM CL A 30041R108 5,111 274,364 SH   DFND 2 89,242 0 185,122
EverQuote Inc COM CL A 30041R108 2,138 114,740 SH   DFND 3 114,740 0 0
EverQuote Inc COM CL A 30041R108 4,314 231,550 SH   SOLE 0 231,550 0 0
Everbridge Inc COM 29978A104 49,962 330,786 SH   DFND 1 330,786 0 0
Everbridge Inc COM 29978A104 31,640 209,484 SH   DFND 2 68,608 0 140,876
Everbridge Inc COM 29978A104 13,201 87,403 SH   DFND 3 87,403 0 0
Everbridge Inc COM 29978A104 22,421 148,446 SH   SOLE 0 148,446 0 0
Eversource Energy COM 30040W108 44,289 541,700 SH   DFND 1 541,700 0 0
Eversource Energy COM 30040W108 92 1,128 SH   DFND 2 1,128 0 0
Eversource Energy COM 30040W108 2,543 31,107 SH   DFND 3 31,107 0 0
Exact Sciences COM 30063P105 104,013 1,089,714 SH   DFND 1 1,089,714 0 0
Exact Sciences COM 30063P105 160,500 1,681,507 SH   DFND 2 1,356,934 0 324,573
Exact Sciences COM 30063P105 48,267 505,675 SH   DFND 3 360,915 0 144,760
Exact Sciences COM 30063P105 112,214 1,175,631 SH   SOLE 0 1,061,911 0 113,720
Exelixis COM 30161Q104 25 1,200 SH   DFND 3 1,200 0 0
Exelon Corporation COM 30161N101 1,076 22,268 SH   DFND 1 22,268 0 0
Expedia Group Inc COM 30212P303 27 165 SH   DFND 3 165 0 0
Expeditors Intl COM 302130109 15 126 SH   DFND 3 126 0 0
Exponent COM 30214U102 27 242 SH   DFND 3 242 0 0
Facebook Cl.A CL A 30303M102 266,276 784,571 SH   DFND 1 784,571 0 0
Facebook Cl.A CL A 30303M102 1,568,399 4,621,228 SH   DFND 2 2,268,773 0 2,352,455
Facebook Cl.A CL A 30303M102 223,802 659,425 SH   DFND 3 460,314 0 199,111
Facebook Cl.A CL A 30303M102 624,266 1,839,378 SH   SOLE 0 1,249,178 0 590,200
Farfetch ORD SHS CL A 30744W107 68,665 1,832,046 SH   DFND 1 1,832,046 0 0
Farfetch ORD SHS CL A 30744W107 214,178 5,714,469 SH   DFND 2 5,327,067 0 387,402
Farfetch ORD SHS CL A 30744W107 47,721 1,273,227 SH   DFND 3 675,682 0 597,545
Farfetch ORD SHS CL A 30744W107 232,263 6,196,982 SH   SOLE 0 5,204,944 0 992,038
Fastenal COM 311900104 52,749 1,022,074 SH   DFND 1 1,022,074 0 0
Fastenal COM 311900104 20,032 388,139 SH   DFND 2 370,349 0 17,790
Fastenal COM 311900104 5,223 101,192 SH   DFND 3 73,992 0 27,200
Fastenal COM 311900104 42,240 818,452 SH   SOLE 0 818,452 0 0
Fastly CL A 31188V100 8 205 SH   DFND 3 205 0 0
Ferrari NV COM N3167Y103 1,848,670 8,815,282 SH   DFND 2 7,211,276 0 1,604,006
Ferrari NV COM N3167Y103 285,192 1,359,921 SH   SOLE 0 1,359,921 0 0
Fibrogen Inc COM 31572Q808 5 467 SH   DFND 3 467 0 0
First Industrial REIT COM 32054K103 63,767 1,224,400 SH   DFND 1 1,224,400 0 0
First Industrial REIT COM 32054K103 159 3,053 SH   DFND 2 3,053 0 0
First Industrial REIT COM 32054K103 3,445 66,148 SH   DFND 3 66,148 0 0
First Majestic Silver COM 32076V103 92 8,100 SH   DFND 2 8,100 0 0
First Republic Bank COM 33616C100 351,080 1,820,198 SH   DFND 1 1,820,198 0 0
First Republic Bank COM 33616C100 493,468 2,558,419 SH   DFND 2 2,484,887 0 73,532
First Republic Bank COM 33616C100 32,384 167,898 SH   DFND 3 150,481 0 17,417
First Republic Bank COM 33616C100 71,266 369,482 SH   SOLE 0 369,482 0 0
FirstCash COM 33767D105 17,773 203,120 SH   DFND 1 203,120 0 0
FirstCash COM 33767D105 1,003 11,467 SH   DFND 3 11,467 0 0
Fiverr Intl ORD SHS M4R82T106 11 61 SH   DFND 3 61 0 0
Fortis COM 349553107 1,351 30,457 SH   DFND 1 30,457 0 0
Fortive Corp COM 34959J108 6,903 97,814 SH   DFND 2 97,814 0 0
Fox COM 35137L105 14 359 SH   DFND 3 359 0 0
Freshpet Inc COM 358039105 28 196 SH   DFND 2 196 0 0
Full Truck Alliance - converted at IPO SPONS ADS 35969L108 95,951 125,181,008 SH   SOLE 0 125,181,008 0 0
Full Truck Alliance Co Ltd ADR SPONS ADS 35969L108 246,438 16,075,519 SH   DFND 2 15,898,233 0 177,286
Futu Hdgs ADR SPON ADR CL A 36118L106 92,549 1,016,800 SH   DFND 2 799,700 0 217,100
GAN COM G3728V109 9 572 SH   DFND 3 572 0 0
Gentex Corp COM 371901109 17 516 SH   DFND 3 516 0 0
Ginkgo Bioworks Holdings Inc CL A COM 37611X100 46,168 3,983,452 SH   DFND 1 3,983,452 0 0
Ginkgo Bioworks Holdings Inc CL A COM 37611X100 60,617 5,230,080 SH   DFND 2 5,210,788 0 19,292
Ginkgo Bioworks Holdings Inc CL A COM 37611X100 3,036 261,983 SH   DFND 3 261,983 0 0
Ginkgo Bioworks Holdings Inc CL A COM 37611X100 944,901 81,527,295 SH   SOLE 0 81,527,295 0 0
Glaukos Corp COM 377322102 36,690 761,687 SH   DFND 1 761,687 0 0
Glaukos Corp COM 377322102 47,140 978,619 SH   DFND 2 949,707 0 28,912
Glaukos Corp COM 377322102 6,928 143,822 SH   DFND 3 135,648 0 8,174
Glaukos Corp COM 377322102 6,561 136,197 SH   SOLE 0 136,197 0 0
Global Blood Therapeutics Inc COM 37890U108 21 835 SH   DFND 3 835 0 0
Golub Capital BDC Inc COM 38173M102 21,070 1,332,700 SH   DFND 1 1,332,700 0 0
Golub Capital BDC Inc COM 38173M102 48 3,018 SH   DFND 2 3,018 0 0
Golub Capital BDC Inc COM 38173M102 1,211 76,612 SH   DFND 3 76,612 0 0
Goodyear Tire & Rubber Co/The COM 382550101 25 1,400 SH   DFND 3 1,400 0 0
Graco COM 384109104 25 363 SH   DFND 3 363 0 0
Grainger, WW COM 384802104 23 59 SH   DFND 3 59 0 0
HDFC Bank ADR ADR REPS 3 SHS 40415F101 4,509 61,687 SH   DFND 1 61,687 0 0
HDFC Bank ADR ADR REPS 3 SHS 40415F101 63,545 869,411 SH   DFND 2 804,937 0 64,474
HDFC Bank ADR ADR REPS 3 SHS 40415F101 15,086 206,407 SH   DFND 3 120,627 0 85,780
HDFC Bank ADR ADR REPS 3 SHS 40415F101 85,875 1,174,926 SH   SOLE 0 1,071,634 0 103,292
HUYA ADR ADS REP SHS A 44852D108 14,449 1,732,547 SH   DFND 1 1,732,547 0 0
HUYA ADR ADS REP SHS A 44852D108 37,363 4,479,938 SH   DFND 2 2,413,097 0 2,066,841
HUYA ADR ADS REP SHS A 44852D108 3,346 401,194 SH   DFND 3 33,165 0 368,029
HUYA ADR ADS REP SHS A 44852D108 8,499 1,019,065 SH   SOLE 0 1,019,065 0 0
Halozyme Therapeutics COM 40637H109 36 880 SH   DFND 3 880 0 0
Harris Corp COM 502431109 13 61 SH   DFND 3 61 0 0
Health Catalyst Inc COM 42225T107 3,294 65,863 SH   DFND 1 65,863 0 0
Health Catalyst Inc COM 42225T107 7,341 146,800 SH   DFND 2 146,800 0 0
Health Catalyst Inc COM 42225T107 8,419 168,340 SH   DFND 3 168,340 0 0
Healthcare Services Group Inc COM 421906108 4 157 SH   DFND 3 157 0 0
Hecla Mining Co COM 422704106 92 16,700 SH   DFND 2 16,700 0 0
Heron Therapeutics Inc COM 427746102 3 308 SH   DFND 3 308 0 0
Hillenbrand COM 431571108 7 170 SH   DFND 3 170 0 0
Home Depot COM 437076102 18 56 SH   DFND 3 56 0 0
Homology Medicines COM 438083107 4 481 SH   DFND 3 481 0 0
Howard Hughes COM 44267D107 51,412 585,486 SH   DFND 1 585,486 0 0
Howard Hughes COM 44267D107 128,314 1,461,271 SH   DFND 2 1,362,861 0 98,410
Howard Hughes COM 44267D107 26,410 300,767 SH   DFND 3 145,504 0 155,263
Howard Hughes COM 44267D107 96,211 1,095,670 SH   SOLE 0 967,471 0 128,199
Hubbell COM 443510607 16 87 SH   DFND 3 87 0 0
Hubspot Inc COM 443573100 89 132 SH   DFND 3 132 0 0
Humana COM 444859102 22 56 SH   DFND 3 56 0 0
Hutchison China Meditech SPONSORED ADR 44842L103 4,521 123,500 SH   DFND 1 123,500 0 0
Hutchison China Meditech SPONSORED ADR 44842L103 2,226 60,804 SH   DFND 2 124 0 60,680
Hutchison China Meditech SPONSORED ADR 44842L103 6,724 183,661 SH   DFND 3 72 0 183,589
ICICI Bank ADR ADR 45104G104 168,628 8,936,327 SH   DFND 1 8,936,327 0 0
ICICI Bank ADR ADR 45104G104 183,730 9,736,631 SH   DFND 2 9,095,160 0 641,471
ICICI Bank ADR ADR 45104G104 73,287 3,883,789 SH   DFND 3 2,679,250 0 1,204,539
ICICI Bank ADR ADR 45104G104 7,545 399,861 SH   DFND 4 399,861 0 0
ICICI Bank ADR ADR 45104G104 186,568 9,887,005 SH   SOLE 0 8,628,526 0 1,258,479
IPG Photonics Corp COM 44980X109 19,126 120,747 SH   DFND 1 120,747 0 0
IPG Photonics Corp COM 44980X109 17,970 113,449 SH   DFND 2 37,181 0 76,268
IPG Photonics Corp COM 44980X109 7,485 47,252 SH   DFND 3 47,252 0 0
IPG Photonics Corp COM 44980X109 14,309 90,336 SH   SOLE 0 90,336 0 0
Iac/Interactivecorp COM 44891N208 29,361 225,349 SH   DFND 1 225,349 0 0
Iac/Interactivecorp COM 44891N208 96,732 742,436 SH   DFND 2 687,927 0 54,509
Iac/Interactivecorp COM 44891N208 21,123 162,123 SH   DFND 3 76,365 0 85,758
Iac/Interactivecorp COM 44891N208 76,374 586,183 SH   SOLE 0 515,433 0 70,750
Iclick Interactive Asia G SPON ADR 45113Y104 19,737 3,569,062 SH   DFND 1 3,569,062 0 0
Iclick Interactive Asia G SPON ADR 45113Y104 5,639 1,019,641 SH   DFND 2 1,019,641 0 0
Iclick Interactive Asia G SPON ADR 45113Y104 258 46,694 SH   DFND 3 46,694 0 0
Iclick Interactive Asia G SPON ADR 45113Y104 3,824 691,490 SH   SOLE 0 691,490 0 0
Ii-Vi Inc COM 902104108 32 533 SH   DFND 3 533 0 0
Illumina COM 452327109 856,873 2,112,554 SH   DFND 1 2,112,554 0 0
Illumina COM 452327109 4,594,327 11,326,958 SH   DFND 2 7,805,089 0 3,521,869
Illumina COM 452327109 483,932 1,193,097 SH   DFND 3 943,466 0 249,631
Illumina COM 452327109 2,432,056 5,996,046 SH   SOLE 0 5,300,890 0 695,156
InMode SHS M5425M103 49 308 SH   DFND 3 308 0 0
Incyte Corp COM 45337C102 11 165 SH   DFND 3 165 0 0
Infinera COM 45667G103 24 2,941 SH   DFND 3 2,941 0 0
Infosys Ltd ADR SPONSORED ADR 456788108 26,511 1,191,515 SH   DFND 1 1,191,515 0 0
Infosys Ltd ADR SPONSORED ADR 456788108 20,791 934,422 SH   DFND 2 89,063 0 845,359
Infosys Ltd ADR SPONSORED ADR 456788108 16,318 733,384 SH   DFND 3 610,967 0 122,417
Infosys Ltd ADR SPONSORED ADR 456788108 3,403 152,945 SH   DFND 4 152,945 0 0
Inogen Inc COM 45780L104 6 141 SH   DFND 3 141 0 0
Insmed Inc COM 457669307 19 707 SH   DFND 3 707 0 0
Inspire Medical Systems COM 457730109 40 170 SH   DFND 3 170 0 0
Intercept Pharmaceuticals Inc COM 45845P108 1 101 SH   DFND 3 101 0 0
International Game Technology SHS G4863A108 29 1,100 SH   DFND 3 1,100 0 0
Intersect ENT COM 46071F103 12 440 SH   DFND 3 440 0 0
Intuitive Surgical COM NEW 46120E602 129,299 130,060 SH   DFND 1 130,060 0 0
Intuitive Surgical COM NEW 46120E602 991,605 997,440 SH   DFND 2 313,811 0 683,629
Intuitive Surgical COM NEW 46120E602 115,034 115,711 SH   DFND 3 95,926 0 19,785
Intuitive Surgical COM NEW 46120E602 264,923 266,482 SH   SOLE 0 123,542 0 142,940
Invitae COM 46185L103 23 800 SH   DFND 3 800 0 0
Ionis Pharmaceuticals COM 462222100 1,766 52,652 SH   DFND 1 52,652 0 0
Ionis Pharmaceuticals COM 462222100 3,803 113,397 SH   DFND 2 113,397 0 0
Ionis Pharmaceuticals COM 462222100 4,560 135,954 SH   DFND 3 135,954 0 0
Ironwood Pharmaceuticals Inc COM 46333X108 12 935 SH   DFND 3 935 0 0
Itau Unibanco Holding SA-ADR SPON ADR REP PFD 465562106 15,610 2,962,059 SH   DFND 1 2,962,059 0 0
Itau Unibanco Holding SA-ADR SPON ADR REP PFD 465562106 198,458 37,658,110 SH   DFND 2 24,525,687 0 13,132,423
Itau Unibanco Holding SA-ADR SPON ADR REP PFD 465562106 49,048 9,307,029 SH   DFND 3 1,230,276 0 8,076,753
Itau Unibanco Holding SA-ADR SPON ADR REP PFD 465562106 2,030 385,212 SH   DFND 4 385,212 0 0
Itron Inc COM 465741106 15 204 SH   DFND 3 204 0 0
J&J Snack Foods Corp COM 466032109 13 83 SH   DFND 3 83 0 0
JD.Com Inc - ADR SPON ADR CL A 47215P106 100,142 1,386,239 SH   DFND 1 1,386,239 0 0
JD.Com Inc - ADR SPON ADR CL A 47215P106 4,940 68,377 SH   DFND 2 68,377 0 0
JD.Com Inc - ADR SPON ADR CL A 47215P106 77 1,066 SH   DFND 3 1,066 0 0
JD.Com Inc - ADR SPON ADR CL A 47215P106 21,090 291,937 SH   SOLE 0 291,937 0 0
JDS Uniphase Corporation COM 925550105 18 1,142 SH   DFND 3 1,142 0 0
JFrog Ltd ORD SHS M6191J100 17,504 522,500 SH   DFND 1 522,500 0 0
JFrog Ltd ORD SHS M6191J100 9,692 289,316 SH   DFND 2 94,529 0 194,787
JFrog Ltd ORD SHS M6191J100 4,111 122,707 SH   DFND 3 122,707 0 0
JFrog Ltd ORD SHS M6191J100 11,993 358,000 SH   SOLE 0 358,000 0 0
Jack Henry & Associates COM 426281101 12 71 SH   DFND 3 71 0 0
Jackson Financial CDI COM CL A 46817M107 527 20,266 SH   DFND 1 20,266 0 0
Jackson Financial CDI COM CL A 46817M107 209 8,026 SH   DFND 2 8,026 0 0
Jackson Financial CDI COM CL A 46817M107 236 9,080 SH   DFND 3 6,185 0 2,895
Jackson Financial CDI COM CL A 46817M107 14 535 SH   SOLE 0 535 0 0
Jaguar Health - US indemnity shares COM 47010C409 0 2,033,592 SH   SOLE 0 2,033,592 0 0
Joby Aviation Inc COM G65163100 77,233 7,677,200 SH   SOLE 0 7,677,200 0 0
John Wiley & Sons Inc COM 968223206 8 153 SH   DFND 3 153 0 0
Johnson & Johnson COM 478160104 14 89 SH   DFND 3 89 0 0
Jumia Technologies Ag ADR SPONSORED ADS 48138M105 176,392 9,488,528 SH   DFND 2 9,064,585 0 423,943
Jumia Technologies Ag ADR SPONSORED ADS 48138M105 7 374 SH   DFND 3 374 0 0
KE Holdings ADR ADR 482497104 39,790 2,179,095 SH   DFND 1 2,179,095 0 0
KE Holdings ADR ADR 482497104 234,186 12,825,059 SH   DFND 2 6,313,220 0 6,511,839
KE Holdings ADR ADR 482497104 18,172 995,165 SH   DFND 3 729,540 0 265,625
KE Holdings ADR ADR 482497104 88,332 4,837,457 SH   SOLE 0 3,707,213 0 1,130,244
Kaleido Biosciences Inc COM 483347100 2,011 368,288 SH   DFND 1 368,288 0 0
Kaleido Biosciences Inc COM 483347100 10 1,836 SH   DFND 2 1,836 0 0
Kaleido Biosciences Inc COM 483347100 1,579 289,103 SH   SOLE 0 289,103 0 0
Keysight Technologies COM 49338L103 26 158 SH   DFND 3 158 0 0
Kingsoft Cloud Holdings Ltd ADR SPON ADR 49639K101 56,197 1,984,362 SH   DFND 1 1,984,362 0 0
Kingsoft Cloud Holdings Ltd ADR SPON ADR 49639K101 103,590 3,657,847 SH   DFND 2 2,367,809 0 1,290,038
Kingsoft Cloud Holdings Ltd ADR SPON ADR 49639K101 9,250 326,627 SH   DFND 3 42,758 0 283,869
Kingsoft Cloud Holdings Ltd ADR SPON ADR 49639K101 11,134 393,153 SH   SOLE 0 393,153 0 0
Knowles Corp COM 49926D109 22 1,200 SH   DFND 3 1,200 0 0
Korea Electric Power ADR SPONSORED ADR 500631106 22 2,224 SH   DFND 2 2,224 0 0
Korea Electric Power ADR SPONSORED ADR 500631106 1,593 161,422 SH   DFND 3 161,422 0 0
Kulicke & Soffa Industries Inc COM 501242101 29 491 SH   DFND 3 491 0 0
Lci Industries COM 50189K103 12 86 SH   DFND 3 86 0 0
Lemonade Inc COM 52567D107 114,780 1,712,881 SH   DFND 1 1,712,881 0 0
Lemonade Inc COM 52567D107 156,964 2,342,398 SH   DFND 2 2,266,258 0 76,140
Lemonade Inc COM 52567D107 7,426 110,822 SH   DFND 3 110,822 0 0
Lemonade Inc COM 52567D107 57,868 863,575 SH   SOLE 0 863,575 0 0
LendingTree COM 52603B107 43,054 307,900 SH   DFND 1 307,900 0 0
LendingTree COM 52603B107 71,817 513,605 SH   DFND 2 359,755 0 153,850
LendingTree COM 52603B107 22,284 159,363 SH   DFND 3 121,573 0 37,790
LendingTree COM 52603B107 46,011 329,049 SH   SOLE 0 303,218 0 25,831
Li Auto ADR SPONS ADS 50202M102 49,746 1,892,209 SH   DFND 1 1,892,209 0 0
Li Auto ADR SPONS ADS 50202M102 173,605 6,603,449 SH   DFND 2 5,894,445 0 709,004
Li Auto ADR SPONS ADS 50202M102 34,840 1,325,200 SH   DFND 3 619,686 0 705,514
Li Auto ADR SPONS ADS 50202M102 130,814 4,975,791 SH   SOLE 0 4,368,730 0 607,061
Liberty Broadband Corp COM 530307305 12 70 SH   DFND 3 70 0 0
Lightspeed POS COM 53227R106 30 310 SH   DFND 3 310 0 0
Lilium NV CL A COM N52586109 61 5,800 SH   DFND 1 5,800 0 0
Lilium NV CL A COM N52586109 186,023 17,699,615 SH   SOLE 0 17,699,615 0 0
LivePerson Inc COM 538146101 29,021 492,291 SH   DFND 1 492,291 0 0
LivePerson Inc COM 538146101 22,112 375,103 SH   DFND 2 122,443 0 252,660
LivePerson Inc COM 538146101 9,239 156,733 SH   DFND 3 156,733 0 0
LivePerson Inc COM 538146101 14,613 247,880 SH   SOLE 0 247,880 0 0
Liveramp Holdings Inc COM 53815P108 29,065 615,401 SH   DFND 1 615,401 0 0
Liveramp Holdings Inc COM 53815P108 15,260 323,108 SH   DFND 2 105,862 0 217,246
Liveramp Holdings Inc COM 53815P108 6,533 138,318 SH   DFND 3 138,318 0 0
Liveramp Holdings Inc COM 53815P108 13,936 295,075 SH   SOLE 0 295,075 0 0
Logitech International SA SHS H50430232 21 235 SH   DFND 3 235 0 0
Lowes Cos COM 548661107 14 69 SH   DFND 3 69 0 0
Lufax Holding Ltd COM 54975P102 46,865 6,714,184 SH   DFND 1 6,714,184 0 0
Lufax Holding Ltd COM 54975P102 83,982 12,031,797 SH   DFND 2 6,999,496 0 5,032,301
Lufax Holding Ltd COM 54975P102 943 135,102 SH   DFND 3 135,102 0 0
Lufax Holding Ltd COM 54975P102 5,603 802,735 SH   SOLE 0 802,735 0 0
Lumentum Hdgs COM 55024U109 12 141 SH   DFND 3 141 0 0
Lyell Immunopharma Inc COM 55083R104 1,099 74,223 SH   DFND 1 74,223 0 0
Lyell Immunopharma Inc COM 55083R104 2,451 165,597 SH   DFND 2 165,597 0 0
Lyell Immunopharma Inc COM 55083R104 2,777 187,663 SH   DFND 3 187,663 0 0
Lyft Inc Class A Common CL A COM 55087P104 57,590 1,074,643 SH   DFND 1 1,074,643 0 0
Lyft Inc Class A Common CL A COM 55087P104 183,134 3,417,315 SH   DFND 2 3,194,100 0 223,215
Lyft Inc Class A Common CL A COM 55087P104 35,854 669,048 SH   DFND 3 324,765 0 344,283
Lyft Inc Class A Common CL A COM 55087P104 130,415 2,433,566 SH   SOLE 0 2,141,419 0 292,147
MELI Kaszek Pioneer CL A COM G5S74L106 22,100 2,000,000 SH   DFND 2 2,000,000 0 0
MakeMyTrip SHS V5633W109 66,962 2,462,730 SH   DFND 2 1,842,077 0 620,653
Marathon Digital Holdings COM 565788106 11 343 SH   DFND 3 343 0 0
Markel Corp COM 570535104 62,443 52,248 SH   DFND 1 52,248 0 0
Markel Corp COM 570535104 228,553 191,237 SH   DFND 2 178,563 0 12,674
Markel Corp COM 570535104 44,950 37,611 SH   DFND 3 17,622 0 19,989
Markel Corp COM 570535104 166,941 139,684 SH   SOLE 0 122,717 0 16,967
MarketAxess Holdings COM 57060D108 251,753 598,428 SH   DFND 1 598,428 0 0
MarketAxess Holdings COM 57060D108 353,973 841,410 SH   DFND 2 708,605 0 132,805
MarketAxess Holdings COM 57060D108 52,104 123,853 SH   DFND 3 114,746 0 9,107
MarketAxess Holdings COM 57060D108 80,277 190,823 SH   SOLE 0 190,823 0 0
Martin Marietta Materials COM 573284106 176,172 515,606 SH   DFND 1 515,606 0 0
Martin Marietta Materials COM 573284106 588,821 1,723,310 SH   DFND 2 1,610,857 0 112,453
Martin Marietta Materials COM 573284106 107,286 313,996 SH   DFND 3 161,499 0 152,497
Martin Marietta Materials COM 573284106 409,841 1,199,489 SH   SOLE 0 1,046,538 0 152,951
Masimo Corp COM 574795100 4,063 15,009 SH   DFND 1 15,009 0 0
Masimo Corp COM 574795100 8,849 32,688 SH   DFND 2 32,688 0 0
Masimo Corp COM 574795100 10,469 38,671 SH   DFND 3 38,671 0 0
Mastercard Inc-Class A CL A 57636Q104 145,825 419,424 SH   DFND 1 419,424 0 0
Mastercard Inc-Class A CL A 57636Q104 524,943 1,509,846 SH   DFND 2 1,416,932 0 92,914
Mastercard Inc-Class A CL A 57636Q104 100,215 288,240 SH   DFND 3 138,351 0 149,889
Mastercard Inc-Class A CL A 57636Q104 356,505 1,025,383 SH   SOLE 0 898,706 0 126,677
McDonald's COM 580135101 17,180 71,253 SH   DFND 1 71,253 0 0
McDonald's COM 580135101 510 2,115 SH   DFND 2 0 0 2,115
McDonald's COM 580135101 343 1,423 SH   DFND 3 1,423 0 0
McDonald's COM 580135101 22,741 94,316 SH   SOLE 0 94,316 0 0
Medifast Inc COM 58470H101 21 110 SH   DFND 3 110 0 0
Medtronic COM G5960L103 19,503 155,588 SH   DFND 1 155,588 0 0
Medtronic COM G5960L103 424 3,382 SH   DFND 2 0 0 3,382
Medtronic COM G5960L103 345 2,755 SH   DFND 3 2,755 0 0
Medtronic COM G5960L103 19,022 151,755 SH   SOLE 0 151,755 0 0
MercadoLibre COM 58733R102 503,059 299,547 SH   DFND 1 299,547 0 0
MercadoLibre COM 58733R102 6,481,683 3,859,523 SH   DFND 2 3,235,940 0 623,583
MercadoLibre COM 58733R102 275,947 164,313 SH   DFND 3 135,528 0 28,785
MercadoLibre COM 58733R102 9,880 5,883 SH   DFND 4 5,883 0 0
MercadoLibre COM 58733R102 626,495 373,047 SH   SOLE 0 373,047 0 0
Mettler-Toledo COM 592688105 129,053 93,696 SH   DFND 1 93,696 0 0
Mettler-Toledo COM 592688105 585,760 425,277 SH   DFND 2 301,261 0 124,016
Mettler-Toledo COM 592688105 5,279 3,833 SH   DFND 3 3,833 0 0
Mettler-Toledo COM 592688105 37,094 26,931 SH   SOLE 0 26,931 0 0
Microsoft COM 594918104 277,747 985,197 SH   DFND 1 985,197 0 0
Microsoft COM 594918104 885,937 3,142,513 SH   DFND 2 2,947,729 0 194,784
Microsoft COM 594918104 163,001 578,183 SH   DFND 3 275,714 0 302,469
Microsoft COM 594918104 626,291 2,221,519 SH   SOLE 0 1,964,326 0 257,193
Mobile Telesystems ADR SPONSORED ADR 607409109 286 29,700 SH   DFND 1 29,700 0 0
Moderna Inc COM 60770K107 1,909,265 4,960,933 SH   DFND 1 4,960,933 0 0
Moderna Inc COM 60770K107 9,229,086 23,980,373 SH   DFND 2 18,008,291 0 5,972,082
Moderna Inc COM 60770K107 941,346 2,445,944 SH   DFND 3 1,893,606 0 552,338
Moderna Inc COM 60770K107 4,168,074 10,830,104 SH   SOLE 0 9,633,509 0 1,196,595
Momentive Global Inc COM 78489X103 21 1,095 SH   DFND 3 1,095 0 0
MongoDB Inc COM 60937P106 100 213 SH   DFND 3 213 0 0
Monolithic Power Systems Inc COM 609839105 34 70 SH   DFND 3 70 0 0
Moody's Corp COM 615369105 248,115 698,699 SH   DFND 1 698,699 0 0
Moody's Corp COM 615369105 903,926 2,545,482 SH   DFND 2 2,381,245 0 164,237
Moody's Corp COM 615369105 174,939 492,634 SH   DFND 3 232,372 0 260,262
Moody's Corp COM 615369105 626,145 1,763,243 SH   SOLE 0 1,539,485 0 223,758
NIO Inc ADR SPON ADS 62914V106 75,009 2,105,228 SH   DFND 1 2,105,228 0 0
NIO Inc ADR SPON ADS 62914V106 2,130,304 59,789,603 SH   DFND 2 46,015,844 0 13,773,759
NIO Inc ADR SPON ADS 62914V106 69,239 1,943,288 SH   DFND 3 1,621,077 0 322,211
NIO Inc ADR SPON ADS 62914V106 954,488 26,788,885 SH   SOLE 0 24,471,825 0 2,317,060
NV5 Global COM 62945V109 14 138 SH   DFND 3 138 0 0
NVIDIA COM 67066G104 496,372 2,396,081 SH   DFND 1 2,396,081 0 0
NVIDIA COM 67066G104 2,330,430 11,249,421 SH   DFND 2 4,783,234 0 6,466,187
NVIDIA COM 67066G104 258,939 1,249,948 SH   DFND 3 1,054,103 0 195,845
NVIDIA COM 67066G104 1,183,597 5,713,443 SH   SOLE 0 4,416,936 0 1,296,507
Nano Dimension ADR SPONS ADS 63008G203 9 1,600 SH   DFND 3 1,600 0 0
Nanobiotix ADR COM 63009J107 9,640 850,841 SH   DFND 1 850,841 0 0
Nanobiotix ADR COM 63009J107 6,222 549,159 SH   SOLE 0 549,159 0 0
National Instruments Corp COM 636518102 20,603 525,197 SH   DFND 1 525,197 0 0
National Instruments Corp COM 636518102 448 11,424 SH   DFND 2 0 0 11,424
National Instruments Corp COM 636518102 369 9,396 SH   DFND 3 9,396 0 0
National Instruments Corp COM 636518102 19,864 506,350 SH   SOLE 0 506,350 0 0
Nektar Therapeutics COM 640268108 25 1,376 SH   DFND 3 1,376 0 0
NetEase.com ADR SPONSORED ADR 64110W102 12,668 148,337 SH   DFND 1 148,337 0 0
NetEase.com ADR SPONSORED ADR 64110W102 8,843 103,549 SH   DFND 2 209 0 103,340
NetEase.com ADR SPONSORED ADR 64110W102 12 142 SH   DFND 3 142 0 0
Netflix Inc COM 64110L106 770,049 1,261,673 SH   DFND 1 1,261,673 0 0
Netflix Inc COM 64110L106 2,531,695 4,148,008 SH   DFND 2 2,274,680 0 1,873,328
Netflix Inc COM 64110L106 293,581 481,012 SH   DFND 3 379,884 0 101,128
Netflix Inc COM 64110L106 1,278,471 2,094,687 SH   SOLE 0 1,678,740 0 415,947
Nevro Corp COM 64157F103 18 154 SH   DFND 3 154 0 0
New Relic COM 64829B100 53 742 SH   DFND 3 742 0 0
Newmont Mining COM 651639106 1,095 20,172 SH   DFND 1 20,172 0 0
NextEra Energy COM 65339F101 58,697 747,548 SH   DFND 1 747,548 0 0
NextEra Energy COM 65339F101 123 1,570 SH   DFND 2 1,570 0 0
NextEra Energy COM 65339F101 3,573 45,505 SH   DFND 3 45,505 0 0
Nike COM 654106103 15 105 SH   DFND 3 105 0 0
Novanta Inc COM 67000B104 32 206 SH   DFND 2 206 0 0
Novocure Ltd ORD SHS G6674U108 301,918 2,598,934 SH   DFND 1 2,598,934 0 0
Novocure Ltd ORD SHS G6674U108 494,320 4,255,147 SH   DFND 2 3,791,779 0 463,368
Novocure Ltd ORD SHS G6674U108 80,507 693,013 SH   DFND 3 518,840 0 174,173
Novocure Ltd ORD SHS G6674U108 211,733 1,822,611 SH   SOLE 0 1,675,795 0 146,816
Nucana Plc ADR SPONSORED ADR 67022C106 6,244 2,420,041 SH   DFND 1 2,420,041 0 0
Nucana Plc ADR SPONSORED ADR 67022C106 3,197 1,238,989 SH   SOLE 0 1,238,989 0 0
Nutanix Inc COM 67059N108 21 563 SH   DFND 3 563 0 0
Oatly Inc. SPONS ADS 67421J108 342,309 22,639,457 SH   DFND 2 19,435,975 0 3,203,482
Oatly Inc. SPONS ADS 67421J108 16,057 1,061,969 SH   SOLE 0 1,061,969 0 0
On Semiconductor Corp COM 682189105 23 500 SH   DFND 3 500 0 0
OneConnect Financial Technology ADR COM 68248T105 8,425 2,054,800 SH   DFND 1 2,054,800 0 0
OneConnect Financial Technology ADR COM 68248T105 2,613 637,316 SH   DFND 2 207,798 0 429,518
OneConnect Financial Technology ADR COM 68248T105 1,152 281,030 SH   DFND 3 281,030 0 0
Opko Health Inc COM 68375N103 24 6,635 SH   DFND 3 6,635 0 0
Oscar Health Inc COM 687793109 26,857 1,544,374 SH   DFND 1 1,544,374 0 0
Oscar Health Inc COM 687793109 114,711 6,596,357 SH   DFND 2 5,163,907 0 1,432,450
Oscar Health Inc COM 687793109 20,777 1,194,746 SH   DFND 3 616,793 0 577,953
Oscar Health Inc COM 687793109 89,648 5,155,120 SH   SOLE 0 4,662,511 0 492,609
Outset Medical COM 690145107 17 346 SH   DFND 3 346 0 0
Oxford Industries Inc COM 691497309 7 73 SH   DFND 3 73 0 0
Ozon Holdings COM 69269L104 11,866 235,211 SH   DFND 1 235,211 0 0
Ozon Holdings COM 69269L104 91,448 1,812,642 SH   DFND 2 996,950 0 815,692
Ozon Holdings COM 69269L104 696 13,790 SH   DFND 3 13,790 0 0
Pacific Biosciences of California COM 69404D108 14 561 SH   DFND 3 561 0 0
Pacira BioSciences COM 695127100 54,560 974,287 SH   DFND 1 974,287 0 0
Pacira BioSciences COM 695127100 28,793 514,162 SH   DFND 2 228,515 0 285,647
Pacira BioSciences COM 695127100 15,283 272,912 SH   DFND 3 241,737 0 31,175
Pacira BioSciences COM 695127100 18,281 326,446 SH   SOLE 0 326,446 0 0
PagerDuty COM 69553P100 23 567 SH   DFND 3 567 0 0
Pan American Silver Corp COM 697900108 105 4,500 SH   DFND 2 4,500 0 0
Paychex COM 704326107 13 116 SH   DFND 3 116 0 0
Peloton Interactive Inc CL A COM 70614W100 379,986 4,365,150 SH   DFND 1 4,365,150 0 0
Peloton Interactive Inc CL A COM 70614W100 1,442,515 16,571,106 SH   DFND 2 7,735,625 0 8,835,481
Peloton Interactive Inc CL A COM 70614W100 218,288 2,507,616 SH   DFND 3 1,963,079 0 544,537
Peloton Interactive Inc CL A COM 70614W100 413,066 4,745,159 SH   SOLE 0 2,815,763 0 1,929,396
Penumbra Inc COM 70975L107 136,974 513,973 SH   DFND 1 513,973 0 0
Penumbra Inc COM 70975L107 178,275 668,950 SH   DFND 2 647,401 0 21,549
Penumbra Inc COM 70975L107 8,858 33,238 SH   DFND 3 33,238 0 0
Penumbra Inc COM 70975L107 28,671 107,583 SH   SOLE 0 107,583 0 0
Pepsico COM 713448108 33,820 224,852 SH   DFND 1 224,852 0 0
Pepsico COM 713448108 732 4,865 SH   DFND 2 0 0 4,865
Pepsico COM 713448108 605 4,025 SH   DFND 3 4,025 0 0
Pepsico COM 713448108 32,578 216,594 SH   SOLE 0 216,594 0 0
Petrobras Common ADR SPONSORED ADR 71654V408 185,748 17,964,024 SH   DFND 1 17,964,024 0 0
Petrobras Common ADR SPONSORED ADR 71654V408 608,042 58,804,836 SH   DFND 2 28,155,161 0 30,649,675
Petrobras Common ADR SPONSORED ADR 71654V408 176,207 17,041,314 SH   DFND 3 2,539,540 0 14,501,774
Petrobras Common ADR SPONSORED ADR 71654V408 7,300 706,010 SH   DFND 4 706,010 0 0
Petrobras Common ADR SPONSORED ADR 71654V408 12,973 1,254,653 SH   SOLE 0 1,254,653 0 0
Petrobras Pref ADR SP ADR NON VTG 71654V101 19,133 1,913,345 SH   DFND 1 1,913,345 0 0
Petrobras Pref ADR SP ADR NON VTG 71654V101 134,205 13,420,519 SH   DFND 2 8,050,824 0 5,369,695
Petrobras Pref ADR SP ADR NON VTG 71654V101 1,116 111,646 SH   DFND 3 111,646 0 0
Pfizer COM 717081103 22 500 SH   DFND 3 500 0 0
Piedmont Lithium Inc COM 72016P105 12 212 SH   DFND 3 212 0 0
Pinduoduo Inc ADR SPONSORED ADS 722304102 171,533 1,891,837 SH   DFND 1 1,891,837 0 0
Pinduoduo Inc ADR SPONSORED ADS 722304102 1,591,493 17,552,591 SH   DFND 2 7,888,066 0 9,664,525
Pinduoduo Inc ADR SPONSORED ADS 722304102 155,094 1,710,531 SH   DFND 3 1,439,421 0 271,110
Pinduoduo Inc ADR SPONSORED ADS 722304102 574,263 6,333,551 SH   SOLE 0 4,365,022 0 1,968,529
Pinterest COM 72352L106 124,350 2,440,626 SH   DFND 1 2,440,626 0 0
Pinterest COM 72352L106 174,155 3,418,150 SH   DFND 2 3,310,946 0 107,204
Pinterest COM 72352L106 8,224 161,420 SH   DFND 3 161,420 0 0
Pinterest COM 72352L106 27,723 544,112 SH   SOLE 0 544,112 0 0
Plantronics Inc COM 727493108 7 254 SH   DFND 3 254 0 0
Precision BioSciences Inc COM 74019P108 17 1,468 SH   DFND 2 1,468 0 0
Procter & Gamble COM 742718109 41,222 294,862 SH   DFND 1 294,862 0 0
Procter & Gamble COM 742718109 888 6,350 SH   DFND 2 0 0 6,350
Procter & Gamble COM 742718109 736 5,267 SH   DFND 3 5,267 0 0
Procter & Gamble COM 742718109 40,587 290,323 SH   SOLE 0 290,323 0 0
Progyny COM 74340E103 22 396 SH   DFND 3 396 0 0
Prologis Inc REIT COM 74340W103 68,899 549,300 SH   DFND 1 549,300 0 0
Prologis Inc REIT COM 74340W103 170 1,357 SH   DFND 2 1,357 0 0
Prologis Inc REIT COM 74340W103 3,723 29,684 SH   DFND 3 29,684 0 0
Proterra Inc COM 74374T109 107 10,600 SH   DFND 1 10,600 0 0
Ptc Therapeutics Inc COM 69366J200 9 246 SH   DFND 3 246 0 0
Puma Biotechnology COM 74587V107 2 252 SH   DFND 3 252 0 0
Pure Storage Inc COM 74624M102 34 1,364 SH   DFND 3 1,364 0 0
Q2 Holdings Inc COM 74736L109 25,512 318,346 SH   DFND 1 318,346 0 0
Q2 Holdings Inc COM 74736L109 15,149 189,034 SH   DFND 2 62,087 0 126,947
Q2 Holdings Inc COM 74736L109 6,341 79,125 SH   DFND 3 79,125 0 0
Q2 Holdings Inc COM 74736L109 9,796 122,235 SH   SOLE 0 122,235 0 0
Quaker Chemical Corp COM 747316107 20 86 SH   DFND 3 86 0 0
Qualcomm COM 747525103 26 200 SH   DFND 3 200 0 0
Quanterix Corp COM 74766Q101 19,475 391,135 SH   DFND 1 391,135 0 0
Quanterix Corp COM 74766Q101 37 746 SH   DFND 2 746 0 0
Quanterix Corp COM 74766Q101 10,440 209,677 SH   SOLE 0 209,677 0 0
QuantumScape Corp COM CL A 74767V109 69 2,830 SH   DFND 1 2,830 0 0
QuantumScape Corp COM CL A 74767V109 22,412 913,279 SH   SOLE 0 913,279 0 0
Quest Diagnostics COM 74834L100 21 145 SH   DFND 3 145 0 0
Quidel Corp COM 74838J101 18 128 SH   DFND 3 128 0 0
Rambus Inc COM 750917106 16 699 SH   DFND 3 699 0 0
Recursion Pharmaceuticals - converted at IPO CL A 75629V104 295,825 12,856,385 SH   SOLE 0 12,856,385 0 0
Recursion Pharmaceuticals Inc CL A 75629V104 66,900 2,907,422 SH   DFND 1 2,907,422 0 0
Recursion Pharmaceuticals Inc CL A 75629V104 92,762 4,031,371 SH   DFND 2 3,911,808 0 119,563
Recursion Pharmaceuticals Inc CL A 75629V104 11,969 520,153 SH   DFND 3 520,153 0 0
Recursion Pharmaceuticals Inc CL A 75629V104 40,176 1,746,043 SH   SOLE 0 1,746,043 0 0
Redfin COM 75737F108 207,033 4,132,390 SH   DFND 1 4,132,390 0 0
Redfin COM 75737F108 256,260 5,114,964 SH   DFND 2 4,955,129 0 159,835
Redfin COM 75737F108 18,921 377,671 SH   DFND 3 336,074 0 41,597
Redfin COM 75737F108 38,475 767,961 SH   SOLE 0 767,961 0 0
Regeneron Pharmaceuticals COM 75886F107 33 55 SH   DFND 3 55 0 0
Relay Therapeutics Inc COM 75943R102 1,200 38,069 SH   DFND 1 38,069 0 0
Relay Therapeutics Inc COM 75943R102 2,531 80,273 SH   DFND 2 80,273 0 0
Relay Therapeutics Inc COM 75943R102 2,987 94,747 SH   DFND 3 94,747 0 0
ResMed COM 761152107 99,914 379,110 SH   DFND 1 379,110 0 0
ResMed COM 761152107 333,408 1,265,065 SH   DFND 2 1,183,666 0 81,399
ResMed COM 761152107 74,845 283,989 SH   DFND 3 155,988 0 128,001
ResMed COM 761152107 242,987 921,978 SH   SOLE 0 807,899 0 114,079
Research in Motion COM 09228F103 27 2,731 SH   DFND 3 2,731 0 0
Rexford Industrial Realty REIT COM 76169C100 63,674 1,122,000 SH   DFND 1 1,122,000 0 0
Rexford Industrial Realty REIT COM 76169C100 160 2,826 SH   DFND 2 2,826 0 0
Rexford Industrial Realty REIT COM 76169C100 3,436 60,547 SH   DFND 3 60,547 0 0
Ringcentral Inc COM 76680R206 78 358 SH   DFND 3 358 0 0
Ritchie Bros Auctioneers (USA) COM 767744105 102,418 1,661,015 SH   DFND 2 1,536,280 0 124,735
Ritchie Bros. Auctioneers COM 767744105 65,689 1,064,717 SH   DFND 2 603,431 0 461,286
Robert Half International Inc COM 770323103 15 151 SH   DFND 3 151 0 0
Roku COM CL A 77543R102 431,121 1,375,845 SH   DFND 1 1,375,845 0 0
Roku COM CL A 77543R102 594,337 1,896,718 SH   DFND 2 1,836,519 0 60,199
Roku COM CL A 77543R102 28,414 90,679 SH   DFND 3 90,679 0 0
Roku COM CL A 77543R102 90,936 290,207 SH   SOLE 0 290,207 0 0
Rollins Inc COM 775711104 20 562 SH   DFND 3 562 0 0
Royal Caribbean Cruises COM V7780T103 15,858 178,276 SH   DFND 1 178,276 0 0
Royal Caribbean Cruises COM V7780T103 895 10,063 SH   DFND 3 10,063 0 0
Rubius Therapeutics Inc COM 78116T103 15,860 887,000 SH   DFND 1 887,000 0 0
Rubius Therapeutics Inc COM 78116T103 2,735 152,937 SH   DFND 2 57,890 0 95,047
Rubius Therapeutics Inc COM 78116T103 1,222 68,336 SH   DFND 3 68,336 0 0
Rubius Therapeutics Inc COM 78116T103 64,110 3,585,559 SH   SOLE 0 3,585,559 0 0
Ryanair ADR SPONSORED ADR NE 783513203 56,255 511,127 SH   DFND 1 511,127 0 0
Ryanair ADR SPONSORED ADR NE 783513203 1,100,078 9,995,255 SH   DFND 2 8,744,846 0 1,250,409
Ryanair ADR SPONSORED ADR NE 783513203 14,060 127,744 SH   DFND 3 52,924 0 74,820
Ryanair ADR SPONSORED ADR NE 783513203 15,777 143,348 SH   SOLE 0 112,148 0 31,200
S&P Global Inc COM 78409V104 101,244 238,284 SH   DFND 1 238,284 0 0
S&P Global Inc COM 78409V104 371,659 874,717 SH   DFND 2 819,873 0 54,844
S&P Global Inc COM 78409V104 70,206 165,234 SH   DFND 3 78,325 0 86,909
S&P Global Inc COM 78409V104 259,354 610,403 SH   SOLE 0 535,067 0 75,336
SCP Pool Corporation COM 73278L105 33 76 SH   DFND 3 76 0 0
SEA Ltd ADR ADR 81141R100 696,976 2,186,730 SH   DFND 1 2,186,730 0 0
SEA Ltd ADR ADR 81141R100 1,445,830 4,536,223 SH   DFND 2 3,743,336 0 792,887
SEA Ltd ADR ADR 81141R100 188,472 591,323 SH   DFND 3 288,790 0 302,533
SEA Ltd ADR ADR 81141R100 740,498 2,323,276 SH   SOLE 0 2,069,038 0 254,238
Saba Capital Income & Opportunities Fund SH BEN INT 92913A100 1,013 222,592 SH   DFND 1 222,592 0 0
Saba Capital Income & Opportunities Fund SH BEN INT 92913A100 956 210,200 SH   DFND 3 210,200 0 0
Sage Therapeutics Inc COM 78667J108 645 14,553 SH   DFND 1 14,553 0 0
Sage Therapeutics Inc COM 78667J108 1,457 32,882 SH   DFND 2 32,882 0 0
Sage Therapeutics Inc COM 78667J108 1,722 38,863 SH   DFND 3 38,863 0 0
Sailpoint Technologies Holding COM 78781P105 17 388 SH   DFND 3 388 0 0
Salesforce.com COM 79466L302 118,062 435,301 SH   DFND 1 435,301 0 0
Salesforce.com COM 79466L302 920,247 3,392,992 SH   DFND 2 1,118,428 0 2,274,564
Salesforce.com COM 79466L302 102,454 377,751 SH   DFND 3 312,045 0 65,706
Salesforce.com COM 79466L302 240,053 885,087 SH   SOLE 0 409,876 0 475,211
Sana Biotechnology Inc COM 799566104 46,842 2,080,021 SH   DFND 1 2,080,021 0 0
Sana Biotechnology Inc COM 799566104 64,322 2,856,227 SH   DFND 2 2,856,227 0 0
Sana Biotechnology Inc COM 799566104 4,363 193,717 SH   DFND 3 193,717 0 0
Sana Biotechnology Inc COM 799566104 136,468 6,059,867 SH   SOLE 0 6,059,867 0 0
Sarepta Therapeutics Inc COM 803607100 16 177 SH   DFND 3 177 0 0
Schrodinger COM 80810D103 13 242 SH   DFND 3 242 0 0
Schweitzer-Maudit Int. COM 808541106 9 265 SH   DFND 3 265 0 0
Seagen Inc COM 81181C104 22 128 SH   DFND 3 128 0 0
Seer COM CL A 81578P106 8 223 SH   DFND 3 223 0 0
Sei Investments Co COM 784117103 24 400 SH   DFND 3 400 0 0
Service Corp.Intl. COM 817565104 138,302 2,295,092 SH   DFND 1 2,295,092 0 0
Service Corp.Intl. COM 817565104 499,734 8,292,962 SH   DFND 2 7,762,215 0 530,747
Service Corp.Intl. COM 817565104 95,950 1,592,259 SH   DFND 3 749,732 0 842,527
Service Corp.Intl. COM 817565104 352,752 5,853,829 SH   SOLE 0 5,121,442 0 732,387
Shake Shack Inc COM 819047101 14 174 SH   DFND 3 174 0 0
Sherwin-Williams Co COM 824348106 12,435 44,453 SH   DFND 2 44,453 0 0
ShockWave Medical Inc COM 82489T104 35,396 171,923 SH   DFND 1 171,923 0 0
ShockWave Medical Inc COM 82489T104 40,310 195,793 SH   DFND 2 112,489 0 83,304
ShockWave Medical Inc COM 82489T104 27,831 135,181 SH   DFND 3 135,181 0 0
ShockWave Medical Inc COM 82489T104 17,683 85,892 SH   SOLE 0 85,892 0 0
Shopify 'A' CL A 82509L107 1,527,216 1,126,448 SH   DFND 1 1,126,448 0 0
Shopify 'A' CL A 82509L107 4,002,413 2,952,111 SH   DFND 2 2,003,552 0 948,559
Shopify 'A' CL A 82509L107 497,163 366,699 SH   DFND 3 275,379 0 91,320
Shopify 'A' CL A 82509L107 1,409,392 1,039,543 SH   SOLE 0 850,524 0 189,019
Shopify Inc COM 82509L107 13,166 9,702 SH   DFND 2 9,702 0 0
Shopify Inc COM 82509L107 252 186 SH   DFND 3 186 0 0
Silicon Laboratories Inc COM 826919102 18 127 SH   DFND 3 127 0 0
Silicon Motion Technology ADR COM 82706C108 22,541 326,775 SH   DFND 1 326,775 0 0
Silicon Motion Technology ADR COM 82706C108 376 5,450 SH   DFND 2 0 0 5,450
Silicon Motion Technology ADR COM 82706C108 402 5,827 SH   DFND 3 5,827 0 0
Silicon Motion Technology ADR COM 82706C108 21,636 313,651 SH   SOLE 0 313,651 0 0
Silk Road Medical COM 82710M100 13 235 SH   DFND 3 235 0 0
SiteOne Landscape Supply COM 82982L103 96,953 486,052 SH   DFND 1 486,052 0 0
SiteOne Landscape Supply COM 82982L103 337,258 1,690,773 SH   DFND 2 1,578,481 0 112,292
SiteOne Landscape Supply COM 82982L103 67,987 340,837 SH   DFND 3 160,887 0 179,950
SiteOne Landscape Supply COM 82982L103 243,603 1,221,249 SH   SOLE 0 1,067,568 0 153,681
Six Flags Entertainment Corp COM 83001A102 15,516 365,090 SH   DFND 1 365,090 0 0
Six Flags Entertainment Corp COM 83001A102 876 20,611 SH   DFND 3 20,611 0 0
Sixth Street Specialty Lending COM 83012A109 4,779 215,169 SH   DFND 1 215,169 0 0
Sixth Street Specialty Lending COM 83012A109 12 530 SH   DFND 2 530 0 0
Sixth Street Specialty Lending COM 83012A109 275 12,379 SH   DFND 3 12,379 0 0
Smartsheet COM 83200N103 21 311 SH   DFND 3 311 0 0
Snap Inc CL A 83304A106 145,484 1,969,462 SH   DFND 1 1,969,462 0 0
Snap Inc CL A 83304A106 199,069 2,694,857 SH   DFND 2 2,608,498 0 86,359
Snap Inc CL A 83304A106 9,552 129,309 SH   DFND 3 129,309 0 0
Snap Inc CL A 83304A106 32,333 437,707 SH   SOLE 0 437,707 0 0
Snowflake Inc COM 833445109 240,161 794,106 SH   DFND 1 794,106 0 0
Snowflake Inc COM 833445109 455,056 1,504,666 SH   DFND 2 1,430,121 0 74,545
Snowflake Inc COM 833445109 56,331 186,262 SH   DFND 3 107,599 0 78,663
Snowflake Inc COM 833445109 444,174 1,468,685 SH   SOLE 0 1,402,835 0 65,850
Sohu.com COM 83410S108 4,171 200,140 SH   DFND 3 0 0 200,140
Solaredge Technologies Inc COM 83417M104 382 1,442 SH   DFND 1 1,442 0 0
Solaredge Technologies Inc COM 83417M104 44 167 SH   DFND 3 167 0 0
Sorrento Therapeutics COM 83587F202 33 4,314 SH   DFND 3 4,314 0 0
Spire Global Inc COM CL A 848560108 10,852 866,045 SH   SOLE 0 866,045 0 0
Splunk Inc COM 848637104 14,607 100,940 SH   DFND 1 100,940 0 0
Splunk Inc COM 848637104 20,126 139,078 SH   DFND 2 44,915 0 94,163
Splunk Inc COM 848637104 8,417 58,168 SH   DFND 3 58,168 0 0
Splunk Inc COM 848637104 10,692 73,884 SH   SOLE 0 73,884 0 0
Spotify Technology SA SHS L8681T102 298,663 1,325,389 SH   DFND 1 1,325,389 0 0
Spotify Technology SA SHS L8681T102 3,910,037 17,351,723 SH   DFND 2 12,815,644 0 4,536,079
Spotify Technology SA SHS L8681T102 118,629 526,444 SH   DFND 3 400,294 0 126,150
Spotify Technology SA SHS L8681T102 705,311 3,129,988 SH   SOLE 0 2,638,016 0 491,972
Sprout Social COM 85209W109 39,155 321,078 SH   DFND 1 321,078 0 0
Sprout Social COM 85209W109 22,071 180,986 SH   DFND 2 58,858 0 122,128
Sprout Social COM 85209W109 8,961 73,478 SH   DFND 3 73,478 0 0
Sprout Social COM 85209W109 24,350 199,670 SH   SOLE 0 199,670 0 0
Staar Surgical COM PAR $0.01 852312305 191,009 1,486,107 SH   DFND 1 1,486,107 0 0
Staar Surgical COM PAR $0.01 852312305 255,262 1,986,012 SH   DFND 2 1,515,598 0 470,414
Staar Surgical COM PAR $0.01 852312305 74,886 582,635 SH   DFND 3 414,173 0 168,462
Staar Surgical COM PAR $0.01 852312305 181,133 1,409,265 SH   SOLE 0 1,289,984 0 119,281
Stamps.Com COM NEW 852857200 16 47 SH   DFND 3 47 0 0
Stanley Black & Decker COM 854502101 13 77 SH   DFND 3 77 0 0
Starbucks Corp COM 855244109 16,060 145,588 SH   DFND 1 145,588 0 0
Starbucks Corp COM 855244109 268 2,429 SH   DFND 2 0 0 2,429
Starbucks Corp COM 855244109 210 1,908 SH   DFND 3 1,908 0 0
Starbucks Corp COM 855244109 16,386 148,543 SH   SOLE 0 148,543 0 0
Stericycle Inc COM 858912108 41,023 603,539 SH   DFND 1 603,539 0 0
Stericycle Inc COM 858912108 147,798 2,174,455 SH   DFND 2 2,031,479 0 142,976
Stericycle Inc COM 858912108 28,598 420,745 SH   DFND 3 200,043 0 220,702
Stericycle Inc COM 858912108 106,395 1,565,319 SH   SOLE 0 1,366,206 0 199,113
Stitch Fix COM CL A 860897107 33 828 SH   DFND 2 828 0 0
StoneCo COM CL A G85158106 5,569 160,397 SH   DFND 1 160,397 0 0
StoneCo COM CL A G85158106 46,083 1,327,279 SH   DFND 2 763,478 0 563,801
StoneCo COM CL A G85158106 317 9,131 SH   DFND 3 9,131 0 0
StoneCo Brazil DR COM CL A G85158106 244 6,994 SH   DFND 3 6,994 0 0
Stratasys SHS M85548101 4,870 226,300 SH   DFND 1 226,300 0 0
Stratasys SHS M85548101 7,760 360,617 SH   DFND 2 113,567 0 247,050
Stratasys SHS M85548101 3,074 142,866 SH   DFND 3 142,866 0 0
Stratasys SHS M85548101 3,112 144,600 SH   SOLE 0 144,600 0 0
Stryker COM 863667101 14 54 SH   DFND 3 54 0 0
Summit Therapeutics New Listing COM 86627T108 1,075 214,617 SH   DFND 1 214,617 0 0
Summit Therapeutics New Listing COM 86627T108 1,112 221,895 SH   SOLE 0 221,895 0 0
Sumo Logic COM 86646P103 12 726 SH   DFND 3 726 0 0
Sunpower Corp COM 867652406 29 1,269 SH   DFND 3 1,269 0 0
Sutro Biopharma COM 869367102 19,691 1,042,428 SH   DFND 1 1,042,428 0 0
Sutro Biopharma COM 869367102 34 1,786 SH   DFND 2 1,786 0 0
Sutro Biopharma COM 869367102 14,181 750,726 SH   SOLE 0 750,726 0 0
Symantec Corp COM 668771108 14 554 SH   DFND 3 554 0 0
Synopsys COM 871607107 34 112 SH   DFND 3 112 0 0
T. Rowe Price COM 74144T108 19,361 98,427 SH   DFND 1 98,427 0 0
T. Rowe Price COM 74144T108 417 2,119 SH   DFND 2 0 0 2,119
T. Rowe Price COM 74144T108 345 1,753 SH   DFND 3 1,753 0 0
T. Rowe Price COM 74144T108 19,347 98,357 SH   SOLE 0 98,357 0 0
TAL Education Group ADR ADS REPSTG COM 874080104 106,799 22,065,841 SH   DFND 2 20,827,296 0 1,238,545
TJX Companies COM 872540109 5,733 86,893 SH   DFND 2 86,893 0 0
TSMC ADR SPONSORED ADR 874039100 716,039 6,413,245 SH   DFND 2 4,950,569 0 1,462,676
TSMC ADR SPONSORED ADR 874039100 2,506 22,445 SH   DFND 3 22,445 0 0
TSMC ADR SPONSORED ADR 874039100 108,623 972,888 SH   SOLE 0 800,814 0 172,074
Tabula Rasa HealthCare Inc COM 873379101 14,708 561,175 SH   DFND 1 561,175 0 0
Tabula Rasa HealthCare Inc COM 873379101 4,632 176,716 SH   DFND 2 57,225 0 119,491
Tabula Rasa HealthCare Inc COM 873379101 1,914 73,034 SH   DFND 3 73,034 0 0
Tabula Rasa HealthCare Inc COM 873379101 6,253 238,574 SH   SOLE 0 238,574 0 0
Tandem Diabetes Care COM NEW 875372203 23,660 198,192 SH   DFND 1 198,192 0 0
Tandem Diabetes Care COM NEW 875372203 35 295 SH   DFND 2 295 0 0
Tandem Diabetes Care COM NEW 875372203 22 188 SH   DFND 3 188 0 0
Tandem Diabetes Care COM NEW 875372203 17,713 148,377 SH   SOLE 0 148,377 0 0
Tata Motors Ltd ADR COM 876568502 91,669 4,090,544 SH   DFND 1 4,090,544 0 0
Tata Motors Ltd ADR COM 876568502 70,291 3,136,590 SH   DFND 2 3,136,590 0 0
Tata Motors Ltd ADR COM 876568502 1,610 71,835 SH   DFND 3 71,835 0 0
Tata Motors Ltd ADR COM 876568502 38,120 1,701,035 SH   SOLE 0 1,701,035 0 0
Teladoc COM 87918A105 316,802 2,498,241 SH   DFND 1 2,498,241 0 0
Teladoc COM 87918A105 437,194 3,447,628 SH   DFND 2 2,942,262 0 505,366
Teladoc COM 87918A105 150,326 1,185,439 SH   DFND 3 892,594 0 292,845
Teladoc COM 87918A105 212,280 1,673,999 SH   SOLE 0 1,530,615 0 143,384
Telus Corp COM 87971M103 9 397 SH   DFND 3 397 0 0
Tenable Holdings COM 88025T102 15 315 SH   DFND 3 315 0 0
Tencent Music Entertainment ADR SPONSORED ADS 88034P109 31,693 4,371,428 SH   DFND 1 4,371,428 0 0
Tencent Music Entertainment ADR SPONSORED ADS 88034P109 274,167 37,816,187 SH   DFND 2 28,474,818 0 9,341,369
Tencent Music Entertainment ADR SPONSORED ADS 88034P109 13,721 1,892,505 SH   DFND 3 915,865 0 976,640
Tencent Music Entertainment ADR SPONSORED ADS 88034P109 48,831 6,735,243 SH   SOLE 0 5,887,619 0 847,624
Teradyne COM 880770102 92,826 850,290 SH   DFND 1 850,290 0 0
Teradyne COM 880770102 402,303 3,685,106 SH   DFND 2 3,487,908 0 197,198
Teradyne COM 880770102 64,013 586,363 SH   DFND 3 276,219 0 310,144
Teradyne COM 880770102 231,606 2,121,519 SH   SOLE 0 1,853,270 0 268,249
Tesla Inc COM 88160R101 1,458,232 1,880,425 SH   DFND 1 1,880,425 0 0
Tesla Inc COM 88160R101 6,046,941 7,797,675 SH   DFND 2 5,482,354 0 2,315,321
Tesla Inc COM 88160R101 669,899 863,851 SH   DFND 3 666,316 0 197,535
Tesla Inc COM 88160R101 2,567,748 3,311,173 SH   SOLE 0 2,860,392 0 450,781
Texas Roadhouse Inc COM 882681109 12 131 SH   DFND 3 131 0 0
The Trade Desk COM CL A 88339J105 824,466 11,727,821 SH   DFND 1 11,727,821 0 0
The Trade Desk COM CL A 88339J105 2,007,210 28,552,064 SH   DFND 2 19,562,479 0 8,989,585
The Trade Desk COM CL A 88339J105 221,003 3,143,714 SH   DFND 3 2,329,879 0 813,835
The Trade Desk COM CL A 88339J105 608,784 8,659,807 SH   SOLE 0 6,477,756 0 2,182,051
Thermo Fisher Scientific COM 883556102 106,660 186,688 SH   DFND 1 186,688 0 0
Thermo Fisher Scientific COM 883556102 403,056 705,470 SH   DFND 2 661,910 0 43,560
Thermo Fisher Scientific COM 883556102 74,507 130,409 SH   DFND 3 61,554 0 68,855
Thermo Fisher Scientific COM 883556102 271,210 474,699 SH   SOLE 0 415,368 0 59,331
Thor Industries Inc COM 885160101 16 133 SH   DFND 3 133 0 0
Toro Co COM 891092108 24 245 SH   DFND 3 245 0 0
Tractor Supply Co COM 892356106 31 151 SH   DFND 3 151 0 0
TransMedics Group COM 89377M109 27 822 SH   DFND 2 822 0 0
TransMedics Group COM 89377M109 13 400 SH   DFND 3 400 0 0
Trip.com Group Sponsored ADR AMERICAN DEP SHS 89677Q107 101,295 3,294,152 SH   DFND 2 2,584,942 0 709,210
Trupanion COM 898202106 15,348 197,600 SH   DFND 1 197,600 0 0
Trupanion COM 898202106 26,892 346,239 SH   DFND 2 112,118 0 234,121
Trupanion COM 898202106 11,088 142,756 SH   DFND 3 142,756 0 0
Trupanion COM 898202106 57,087 735,000 SH   SOLE 0 735,000 0 0
TuSimple Hdgs CL A 90089L108 13 349 SH   DFND 3 349 0 0
Twilio Inc CL A 90138F102 538,124 1,686,644 SH   DFND 1 1,686,644 0 0
Twilio Inc CL A 90138F102 953,104 2,987,319 SH   DFND 2 2,855,958 0 131,361
Twilio Inc CL A 90138F102 107,355 336,484 SH   DFND 3 211,140 0 125,344
Twilio Inc CL A 90138F102 350,545 1,098,714 SH   SOLE 0 1,000,008 0 98,706
Ultragenyx COM 90400D108 10 115 SH   DFND 3 115 0 0
United Parcel Service CL B 911312106 47,184 259,113 SH   DFND 1 259,113 0 0
United Parcel Service CL B 911312106 1,023 5,617 SH   DFND 2 0 0 5,617
United Parcel Service CL B 911312106 850 4,666 SH   DFND 3 4,666 0 0
United Parcel Service CL B 911312106 47,350 260,022 SH   SOLE 0 260,022 0 0
UnitedHealth COM 91324P102 39 100 SH   DFND 3 100 0 0
Unity Biotechnology Inc COM 91381U101 744 248,000 SH   DFND 1 248,000 0 0
Unity Biotechnology Inc COM 91381U101 1,023 341,111 SH   SOLE 0 341,111 0 0
Upwork Inc COM 91688F104 111,012 2,465,281 SH   DFND 1 2,465,281 0 0
Upwork Inc COM 91688F104 69,629 1,546,272 SH   DFND 2 656,286 0 889,986
Upwork Inc COM 91688F104 35,175 781,137 SH   DFND 3 706,489 0 74,648
Upwork Inc COM 91688F104 54,636 1,213,324 SH   SOLE 0 1,213,324 0 0
Uxin ADR ADS 91818X108 3,344 1,211,500 SH   DFND 1 1,211,500 0 0
Uxin ADR ADS 91818X108 1,558 564,600 SH   SOLE 0 564,600 0 0
Vale SA ADR ADR 91912E105 21,907 1,570,361 SH   DFND 1 1,570,361 0 0
Vale SA ADR ADR 91912E105 172,835 12,389,609 SH   DFND 2 6,564,035 0 5,825,574
Vale SA ADR ADR 91912E105 1,272 91,158 SH   DFND 3 91,158 0 0
Varonis Systems Inc COM 922280102 32 525 SH   DFND 2 525 0 0
Varonis Systems Inc COM 922280102 31 517 SH   DFND 3 517 0 0
Vedanta Ltd ADR COM 92242Y100 18,428 1,206,000 SH   DFND 1 1,206,000 0 0
Vedanta Ltd ADR COM 92242Y100 22,117 1,447,435 SH   DFND 2 1,447,435 0 0
Vedanta Ltd ADR COM 92242Y100 1,340 87,716 SH   DFND 3 87,716 0 0
Vedanta Ltd ADR COM 92242Y100 22,028 1,441,655 SH   SOLE 0 1,441,655 0 0
Veeco Instruments COM 922417100 13,034 586,854 SH   DFND 1 586,854 0 0
Veeco Instruments COM 922417100 11,382 512,454 SH   DFND 2 166,874 0 345,580
Veeco Instruments COM 922417100 4,787 215,536 SH   DFND 3 215,536 0 0
Veeva Systems Inc Class A COM 922475108 1,916 6,648 SH   DFND 1 6,648 0 0
Veeva Systems Inc Class A COM 922475108 4,267 14,807 SH   DFND 2 14,807 0 0
Veeva Systems Inc Class A COM 922475108 4,904 17,016 SH   DFND 3 17,016 0 0
Veoneer Inc COM 92336X109 24 700 SH   DFND 3 700 0 0
Verint Systems Inc COM 92343X100 18 395 SH   DFND 3 395 0 0
Verisk Analytics COM 92345Y106 10,113 50,495 SH   DFND 2 50,495 0 0
Veritone COM 92347M100 14 569 SH   DFND 3 569 0 0
ViewRay COM 92672L107 7 911 SH   DFND 3 911 0 0
Vimeo Inc. COM 92719V100 29,216 994,740 SH   DFND 1 994,740 0 0
Vimeo Inc. COM 92719V100 101,740 3,464,092 SH   DFND 2 3,090,803 0 373,289
Vimeo Inc. COM 92719V100 20,726 705,688 SH   DFND 3 329,154 0 376,534
Vimeo Inc. COM 92719V100 76,653 2,609,904 SH   SOLE 0 2,285,136 0 324,768
Vir Biotechnology Inc COM 92764N102 1,257 28,874 SH   DFND 1 28,874 0 0
Vir Biotechnology Inc COM 92764N102 2,668 61,306 SH   DFND 2 61,306 0 0
Vir Biotechnology Inc COM 92764N102 3,171 72,866 SH   DFND 3 72,866 0 0
Vir Biotechnology Inc COM 92764N102 162,619 3,736,646 SH   SOLE 0 3,736,646 0 0
Visa Inc-Class A Shares COM CL A 92826C839 11,670 52,389 SH   DFND 2 52,389 0 0
Visa Inc-Class A Shares COM CL A 92826C839 27 121 SH   DFND 3 121 0 0
Visteon Corp COM 92839U206 19 200 SH   DFND 3 200 0 0
Vroom Inc COM 92918V109 93,268 4,225,994 SH   DFND 1 4,225,994 0 0
Vroom Inc COM 92918V109 141,923 6,430,576 SH   DFND 2 6,220,990 0 209,586
Vroom Inc COM 92918V109 6,077 275,341 SH   DFND 3 275,341 0 0
Vroom Inc COM 92918V109 19,939 903,446 SH   SOLE 0 903,446 0 0
Vuzix COM 92921W300 10 924 SH   DFND 3 924 0 0
Vyne Therapeutics Inc COM 92941V209 68 48,706 SH   DFND 1 48,706 0 0
Vyne Therapeutics Inc COM 92941V209 70 50,056 SH   SOLE 0 50,056 0 0
WD-40 Co COM 929236107 13 58 SH   DFND 3 58 0 0
WEC Energy Group COM 92939U106 1,344 15,233 SH   DFND 1 15,233 0 0
Wal-Mart Stores COM 931142103 14 101 SH   DFND 3 101 0 0
Warby Parker Inc CL A COM 93403J106 24,576 463,257 SH   DFND 2 179,801 0 283,456
Warby Parker Inc CL A COM 93403J106 240,195 4,527,716 SH   SOLE 0 4,527,716 0 0
Waters COM 941848103 9,025 25,259 SH   DFND 1 25,259 0 0
Waters COM 941848103 11,735 32,843 SH   DFND 2 32,843 0 0
Waters COM 941848103 4,059 11,359 SH   DFND 3 7,820 0 3,539
Waters COM 941848103 240 672 SH   SOLE 0 672 0 0
Watsco Inc COM 942622200 211,367 798,758 SH   DFND 1 798,758 0 0
Watsco Inc COM 942622200 248,713 939,889 SH   DFND 2 910,287 0 29,602
Watsco Inc COM 942622200 16,813 63,536 SH   DFND 3 57,580 0 5,956
Watsco Inc COM 942622200 63,502 239,973 SH   SOLE 0 239,973 0 0
Wayfair Inc Class A CL A 94419L101 714,349 2,795,776 SH   DFND 1 2,795,776 0 0
Wayfair Inc Class A CL A 94419L101 1,103,924 4,320,473 SH   DFND 2 4,061,605 0 258,868
Wayfair Inc Class A CL A 94419L101 117,730 460,766 SH   DFND 3 333,517 0 127,249
Wayfair Inc Class A CL A 94419L101 615,761 2,409,929 SH   SOLE 0 2,309,639 0 100,290
Wheaton Precious Metals COM 962879102 767 20,416 SH   DFND 1 20,416 0 0
Williams-Sonoma Inc COM 969904101 13 76 SH   DFND 3 76 0 0
Wix Com SHS M98068105 651,780 3,325,916 SH   DFND 2 2,070,603 0 1,255,313
Wix Com SHS M98068105 80 406 SH   DFND 3 406 0 0
Workday Inc CL A 98138H101 378,313 1,513,919 SH   DFND 1 1,513,919 0 0
Workday Inc CL A 98138H101 1,393,263 5,575,505 SH   DFND 2 2,600,192 0 2,975,313
Workday Inc CL A 98138H101 154,672 618,961 SH   DFND 3 522,368 0 96,593
Workday Inc CL A 98138H101 335,569 1,342,865 SH   SOLE 0 727,028 0 615,837
XPEL COM 98379L100 22 295 SH   DFND 3 295 0 0
Xencor Inc COM 98401F105 27 828 SH   DFND 2 828 0 0
Xencor Inc COM 98401F105 14 431 SH   DFND 3 431 0 0
Xperi Holding Corp COM 98390M103 34 1,793 SH   DFND 3 1,793 0 0
Xylem COM 98419M100 119,870 969,198 SH   DFND 1 969,198 0 0
Xylem COM 98419M100 35,101 283,801 SH   DFND 2 108,840 0 174,961
Xylem COM 98419M100 113,722 919,489 SH   DFND 3 714,675 0 204,814
Xylem COM 98419M100 11,462 92,673 SH   SOLE 0 92,673 0 0
Yatsen Holding Ltd ADR COM 985194109 4,949 1,298,849 SH   DFND 1 1,298,849 0 0
Yatsen Holding Ltd ADR COM 985194109 41,336 10,849,262 SH   DFND 2 8,742,410 0 2,106,852
Yatsen Holding Ltd ADR COM 985194109 100 26,280 SH   DFND 3 26,280 0 0
Yelp COM 985817105 10 262 SH   DFND 3 262 0 0
Zai Lab ADR ADR 98887Q104 148,551 1,409,535 SH   DFND 1 1,409,535 0 0
Zai Lab ADR ADR 98887Q104 271,039 2,571,771 SH   DFND 2 1,439,989 0 1,131,782
Zai Lab ADR ADR 98887Q104 58,499 555,071 SH   DFND 3 243,498 0 311,573
Zai Lab ADR ADR 98887Q104 693 6,577 SH   DFND 4 6,577 0 0
Zai Lab ADR ADR 98887Q104 37,132 352,327 SH   SOLE 0 352,327 0 0
Ziff Davis Inc COM 48123V102 10 73 SH   DFND 3 73 0 0
Zillow Group Inc Class A CL A 98954M101 105,690 1,193,155 SH   DFND 1 1,193,155 0 0
Zillow Group Inc Class A CL A 98954M101 174,619 1,971,315 SH   DFND 2 1,809,782 0 161,533
Zillow Group Inc Class A CL A 98954M101 12,747 143,907 SH   DFND 3 143,907 0 0
Zillow Group Inc Class A CL A 98954M101 29,111 328,638 SH   SOLE 0 328,638 0 0
Zillow Group Inc Class C CL C CAP STK 98954M200 150,791 1,710,808 SH   DFND 1 1,710,808 0 0
Zillow Group Inc Class C CL C CAP STK 98954M200 304,674 3,456,709 SH   DFND 2 2,711,709 0 745,000
Zillow Group Inc Class C CL C CAP STK 98954M200 73,204 830,543 SH   DFND 3 535,201 0 295,342
Zillow Group Inc Class C CL C CAP STK 98954M200 229,114 2,599,435 SH   SOLE 0 2,344,822 0 254,613
Zoom Video Communications Inc CL A 98980L101 402,425 1,538,909 SH   DFND 1 1,538,909 0 0
Zoom Video Communications Inc CL A 98980L101 1,070,190 4,092,503 SH   DFND 2 2,364,632 0 1,727,871
Zoom Video Communications Inc CL A 98980L101 101,530 388,260 SH   DFND 3 332,433 0 55,827
Zoom Video Communications Inc CL A 98980L101 507,149 1,939,385 SH   SOLE 0 1,588,209 0 351,176
Zuora Inc Class A COM CL A 98983V106 29,491 1,778,724 SH   DFND 1 1,778,724 0 0
Zuora Inc Class A COM CL A 98983V106 15,942 961,512 SH   DFND 2 312,200 0 649,312
Zuora Inc Class A COM CL A 98983V106 6,671 402,365 SH   DFND 3 402,365 0 0
Zuora Inc Class A COM CL A 98983V106 12,956 781,436 SH   SOLE 0 781,436 0 0
Zymergen Inc COM 98985X100 10,621 806,451 SH   SOLE 0 806,451 0 0
Zymergen Inc - converted at IPO COM 98985X100 26,544 2,015,505 SH   SOLE 0 2,015,505 0 0
Zynex COM 98986M103 5 437 SH   DFND 3 437 0 0
Zynga Inc COM 98986T108 22 2,863 SH   DFND 3 2,863 0 0
dLocal CL A G29018101 30,211 553,728 SH   DFND 1 553,728 0 0
dLocal CL A G29018101 13,437 246,272 SH   DFND 3 0 0 246,272
iRobot COM 462726100 16,382 208,682 SH   DFND 1 208,682 0 0
iRobot COM 462726100 9,372 119,385 SH   DFND 3 108,597 0 10,788
iRobot COM 462726100 23,248 296,148 SH   SOLE 0 296,148 0 0
iRobot COM 462726100 18,976 241,733 SH   DFND 2 100,592 0 141,141
iShares Physical Silver ETC (c) COM 46428Q109 55,888 2,623,100 SH   DFND 1 2,623,100 0 0
iShares Physical Silver ETC (c) COM 46428Q109 3,496 164,100 SH   DFND 3 164,100 0 0
nCino COM 63947U107 16 232 SH   DFND 3 232 0 0
nLIGHT COM 65487K100 15 542 SH   DFND 3 542 0 0