The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
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COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
AADI BIOSCIENCES INC COM 00032Q104 22,459 764,701 SH   SOLE   764,701 0 0
ABCAM PLC ADS 000380204 23,262 1,147,588 SH   SOLE   1,147,588 0 0
ACADIA HEALTHCARE COMPANY IN COM 00404A109 45,284 710,000 SH   SOLE   710,000 0 0
ACCOLADE INC COM 00437E102 38,923 923,000 SH   SOLE   923,000 0 0
ACELRX PHARMACEUTICALS INC COM 00444T100 3,896 3,819,402 SH   SOLE   3,819,402 0 0
ACLARIS THERAPEUTICS INC COM 00461U105 68,458 3,803,232 SH   SOLE   3,803,232 0 0
ACUMEN PHARMACEUTICALS INC COM 00509G209 23,467 1,579,191 SH   SOLE   1,579,191 0 0
ADAPTIMMUNE THERAPEUTICS PLC SPONDS ADR 00653A107 11,321 2,189,788 SH   SOLE   2,189,788 0 0
AEGLEA BIOTHERAPEUTICS INC COM 00773J103 12,540 1,577,296 SH   SOLE   1,577,296 0 0
AGILON HEALTH INC COM 00857U107 185,436 7,075,000 SH   SOLE   7,075,000 0 0
AGIOS PHARMACEUTICALS INC COM 00847X104 117,968 2,556,179 SH   SOLE   2,556,179 0 0
AKERO THERAPEUTICS INC COM 00973Y108 12,710 568,701 SH   SOLE   568,701 0 0
ALIGN TECHNOLOGY INC COM 016255101 133,086 200,000 SH   SOLE   200,000 0 0
ALLAKOS INC COM 01671P100 32,365 305,706 SH   SOLE   305,706 0 0
ALNYLAM PHARMACEUTICALS INC COM 02043Q107 58,720 311,000 SH   SOLE   311,000 0 0
AMARIN CORP PLC SPONS ADR NEW 023111206 22,032 4,320,000 SH   SOLE   4,320,000 0 0
AMICUS THERAPEUTICS INC COM 03152W109 9,669 1,012,506 SH   SOLE   1,012,506 0 0
AMRYT PHARMA PLC SPONSORED ADS 03217L106 15,601 1,295,225 SH   SOLE   1,295,225 0 0
ANAPTYSBIO INC COM 032724106 14,532 535,832 SH   SOLE   535,832 0 0
APELLIS PHARMACEUTICALS INC COM 03753U106 872 26,458 SH   SOLE   26,458 0 0
APPLIED THERAPEUTICS INC COM 03828A101 11,648 701,680 SH   SOLE   701,680 0 0
ARGENX SE SPONSORED ADR 04016X101 95,130 315,000 SH   SOLE   315,000 0 0
ARVINAS INC COM 04335A105 47,459 577,500 SH   SOLE   577,500 0 0
ASCENDIS PHARMA A/S SPONSORED ADR 04351P101 63,756 400,000 SH   SOLE   400,000 0 0
ATAI LIFE SCIENCES NV SHS N0731H103 4,698 317,628 SH   SOLE   317,628 0 0
ATEA PHARMACEUTICALS INC COM 04683R106 26,306 750,307 SH   SOLE   750,307 0 0
ATHIRA PHARMA INC COM 04746L104 5,180 552,252 SH   SOLE   552,252 0 0
ATRECA INC CL A COM 04965G109 2,865 459,830 SH   SOLE   459,830 0 0
AURINIA PHARMACEUTICALS INC COM 05156V102 13,572 613,269 SH   SOLE   613,269 0 0
BAXTER INTL INC COM 071813109 36,194 450,000 SH   SOLE   450,000 0 0
BCLS ACQUISITION CORP COM CL A G0904B105 3,078 309,000 SH   SOLE   309,000 0 0
BIOMARIN PHARMACEUTICAL INC COM 09061G101 19,593 253,500 SH   SOLE   253,500 0 0
BIOMEA FUSION INC COM 09077A106 13,952 1,165,582 SH   SOLE   1,165,582 0 0
BLUEPRINT MEDICINES CORP COM 09627Y109 87,353 849,659 SH   SOLE   849,659 0 0
BOLT BIOTHERAPEUTICS INC COM 097702104 20,863 1,649,248 SH   SOLE   1,649,248 0 0
BRIGHT HEALTH GROUP INC COM 10920V107 14,402 1,765,000 SH   SOLE   1,765,000 0 0
CEREVEL THERAPEUTICS HLDNG I COM 15678U128 47,217 1,600,589 SH   SOLE   1,600,589 0 0
CHINOOK THERAPEUTICS INC COM 16961L106 8,781 688,149 SH   SOLE   688,149 0 0
COLLEGIUM PHARMACEUTICAL INC COM 19459J104 17,766 900,000 SH   SOLE   900,000 0 0
COMPUGEN LTD ORD M25722105 7,664 1,283,790 SH   SOLE   1,283,790 0 0
CONMED CORP COM 207410101 21,260 162,500 SH   SOLE   162,500 0 0
COVETRUS INC COM 22304C100 29,450 1,623,500 SH   SOLE   1,623,500 0 0
CULLINAN ONCOLOGY INC COM 230031106 24,283 1,075,912 SH   SOLE   1,075,912 0 0
CYTOKINETICS INC NOTE 4.000%11/1 23282WAA8 28,316 8,000,000 PRN   SOLE   8,000,000 0 0
DAY ONE BIOPHARMACEUTICALS I COM 23954D109 8,933 376,439 SH   SOLE   376,439 0 0
DESIGN THERAPEUTICS INC COM 25056L103 4,907 334,050 SH   SOLE   334,050 0 0
DEXCOM INC COM 252131107 25,429 46,500 SH   SOLE   46,500 0 0
DYNAVAX TECHNOLOGIES CORP COM NEW 268158201 27,469 1,429,921 SH   SOLE   1,429,921 0 0
EARGO INC COM 270087109 6,562 975,000 SH   SOLE   975,000 0 0
EDAP TMS S A SPONSORED ADR 268311107 4,855 760,900 SH   SOLE   760,900 0 0
EDWARDS LIFESCIENCES CORP COM 28176E108 65,888 582,000 SH   SOLE   582,000 0 0
ENCOMPASS HEALTH CORP COM 29261A100 37,520 500,000 SH   SOLE   500,000 0 0
EPIZYME INC COM 29428V104 18,401 3,593,885 SH   SOLE   3,593,885 0 0
ESSA PHARMA INC COM NEW 29668H708 4,064 508,044 SH   SOLE   508,044 0 0
EUCRATES BIOMEDICAL ACQU COR UNIT 10/23/2027 G3141W114 2,050 206,000 SH   SOLE   206,000 0 0
EVOLENT HEALTH INC CL A 30050B101 58,125 1,875,000 SH   SOLE   1,875,000 0 0
EXACT SCIENCES CORP COM 30063P105 54,407 570,000 SH   SOLE   570,000 0 0
FATE THERAPEUTICS INC COM 31189P102 6,520 110,000 SH   SOLE   110,000 0 0
FRESHPET INC COM 358039105 75,198 527,000 SH   SOLE   527,000 0 0
FS DEVELOPMENT CORP II COM CL A 30318F100 2,083 209,332 SH   SOLE   209,332 0 0
F-STAR THERAPEUTICS INC COM 30315R107 7,717 1,054,232 SH   SOLE   1,054,232 0 0
FULCRUM THERAPEUTICS INC COM 359616109 12,844 455,290 SH   SOLE   455,290 0 0
FUSION PHARMACEUTICALS INC COM 36118A100 7,511 948,327 SH   SOLE   948,327 0 0
GALERA THERAPEUTICS INC COM 36338D108 4,603 568,252 SH   SOLE   568,252 0 0
GAMIDA CELL LTD SHS M47364100 8,418 2,147,400 SH   SOLE   2,147,400 0 0
GOSSAMER BIO INC NOTE 5.000% 6/0 38341PAA0 16,253 15,573,000 PRN   SOLE   15,573,000 0 0
GRAPHITE BIO INC COM 38870X104 34,037 2,076,710 SH   SOLE   2,076,710 0 0
GUARDANT HEALTH INC COM 40131M109 25,002 200,000 SH   SOLE   200,000 0 0
HCA HEALTHCARE INC COM 40412C101 109,224 450,000 SH   SOLE   450,000 0 0
HEALTH CATALYST INC COM 42225T107 42,509 850,000 SH   SOLE   850,000 0 0
HELIX ACQUISITION CORP COM CL A G4444C102 1,537 154,500 SH   SOLE   154,500 0 0
HORIZON THERAPEUTICS PUB L SHS G46188101 76,897 702,000 SH   SOLE   702,000 0 0
HUMANA INC COM 444859102 133,089 342,000 SH   SOLE   342,000 0 0
ICOSAVAX INC COM 45114M109 21,725 734,215 SH   SOLE   734,215 0 0
IDEXX LABS INC COM 45168D104 111,942 180,000 SH   SOLE   180,000 0 0
IMARA INC COM 45249V107 3,383 829,102 SH   SOLE   829,102 0 0
IMMUNEERING CORP CLASS A COM 45254E107 28,935 1,089,816 SH   SOLE   1,089,816 0 0
IMMUNOCORE HLDGS PLC ADS 45258D105 90,642 2,445,155 SH   SOLE   2,445,155 0 0
INNOVAGE HLDG CORP COM 45784A104 3,470 525,000 SH   SOLE   525,000 0 0
INOZYME PHARMA INC COM 45790W108 9,852 850,015 SH   SOLE   850,015 0 0
INSULET CORP COM 45784P101 124,369 437,566 SH   SOLE   437,566 0 0
INTERSECT ENT INC COM 46071F103 33,184 1,220,000 SH   SOLE   1,220,000 0 0
INTUITIVE SURGICAL INC COM NEW 46120E602 119,298 120,000 SH   SOLE   120,000 0 0
INVITAE CORP COM 46185L103 74,084 2,605,829 SH   SOLE   2,605,829 0 0
IRHYTHM TECHNOLOGIES INC COM 450056106 26,235 448,000 SH   SOLE   448,000 0 0
JIYA ACQUISITION CORP COM CL A 47760M102 2,010 206,200 SH   SOLE   206,200 0 0
KARUNA THERAPEUTICS INC COM 48576A100 47,943 391,917 SH   SOLE   391,917 0 0
KINNATE BIOPHARMA INC COM 49705R105 7,665 332,986 SH   SOLE   332,986 0 0
KURA ONCOLOGY INC COM 50127T109 15,405 822,500 SH   SOLE   822,500 0 0
KYMERA THERAPEUTICS INC COM 501575104 43,052 732,927 SH   SOLE   732,927 0 0
LEAP THERAPEUTICS INC COM 52187K101 14,068 3,508,270 SH   SOLE   3,508,270 0 0
LEGEND BIOTECH CORP SPONSORED ADS 52490G102 15,937 315,218 SH   SOLE   315,218 0 0
LIFESTANCE HEALTH GROUP INC COM 53228F101 24,469 1,687,500 SH   SOLE   1,687,500 0 0
MACROGENICS INC COM 556099109 13,440 641,816 SH   SOLE   641,816 0 0
MADRIGAL PHARMACEUTICALS INC COM 558868105 20,945 262,500 SH   SOLE   262,500 0 0
MEREO BIOPHARMA GROUP PLC ADS 589492107 11,696 4,832,978 SH   SOLE   4,832,978 0 0
MERSANA THERAPEUTICS INC COM 59045L106 28,485 3,020,702 SH   SOLE   3,020,702 0 0
MIRATI THERAPEUTICS INC COM 60468T105 62,540 353,514 SH   SOLE   353,514 0 0
MIRUM PHARMACEUTICALS INC COM 604749101 30,390 1,525,623 SH   SOLE   1,525,623 0 0
NEUROCRINE BIOSCIENCES INC COM 64125C109 100,849 1,051,500 SH   SOLE   1,051,500 0 0
NEUROCRINE BIOSCIENCES INC NOTE 2.250% 5/1 64125CAD1 1,336 1,000,000 PRN   SOLE   1,000,000 0 0
NEVRO CORP COM 64157F103 73,983 635,700 SH   SOLE   635,700 0 0
NEVRO CORP NOTE 2.750% 4/0 64157FAC7 675 500,000 PRN   SOLE   500,000 0 0
NKARTA INC COM 65487U108 13,993 503,148 SH   SOLE   503,148 0 0
NOVAVAX INC COM NEW 670002401 94,326 455,000 SH   SOLE   455,000 0 0
NOVOCURE LTD ORD SHS G6674U108 20,330 175,000 SH   SOLE   175,000 0 0
NURIX THERAPEUTICS INC COM 67080M103 9,541 318,450 SH   SOLE   318,450 0 0
NUVATION BIO INC *W EXP 07/07/202 67080N119 343 134,028 SH   SOLE   134,028 0 0
NUVATION BIO INC COM CL A 67080N101 2,352 236,609 SH   SOLE   236,609 0 0
OAK STR HEALTH INC COM 67181A107 18,756 441,000 SH   SOLE   441,000 0 0
OLINK HLDG AB SPONSORED ADS 680710100 12,246 505,000 SH   SOLE   505,000 0 0
ORION ACQUISITION CORP UNIT 02/19/2026 68626A207 9,895 1,000,000 SH   SOLE   1,000,000 0 0
PACIRA BIOSCIENCES INC COM 695127100 56,000 1,000,000 SH   SOLE   1,000,000 0 0
PACIRA BIOSCIENCES INC NOTE 2.375% 4/0 695127AD2 1,038 1,000,000 PRN   SOLE   1,000,000 0 0
PARATEK PHARMACEUTICALS INC COM 699374302 8,092 1,665,014 SH   SOLE   1,665,014 0 0
PENUMBRA INC COM 70975L107 39,309 147,500 SH   SOLE   147,500 0 0
PHASEBIO PHARMACEUTICALS INC COM 717224109 5,734 1,843,764 SH   SOLE   1,843,764 0 0
PHREESIA INC COM 71944F106 59,849 970,000 SH   SOLE   970,000 0 0
POPULATION HEALTH INVS CO IN UNIT 99/99/9999 G71716123 2,011 201,044 SH   SOLE   201,044 0 0
POSEIDA THERAPEUTICS INC COM 73730P108 2,112 289,754 SH   SOLE   289,754 0 0
PRELUDE THERAPEUTICS INC COM 74065P101 11,324 362,359 SH   SOLE   362,359 0 0
PROMETHEUS BIOSCIENCES INC COM 74349U108 14,466 610,136 SH   SOLE   610,136 0 0
PROTHENA CORP PLC SHS G72800108 50,604 710,430 SH   SOLE   710,430 0 0
PULMONX CORP COM 745848101 25,186 700,000 SH   SOLE   700,000 0 0
RADIUS HEALTH INC NOTE 3.000% 9/0 750469AA6 1,370 1,500,000 PRN   SOLE   1,500,000 0 0
RELAY THERAPEUTICS INC COM 75943R102 14,805 469,560 SH   SOLE   469,560 0 0
RENEO PHARMACEUTICALS INC COM 75974E103 8,517 1,143,185 SH   SOLE   1,143,185 0 0
RHYTHM PHARMACEUTICALS INC COM 76243J105 7,995 612,180 SH   SOLE   612,180 0 0
RIGEL PHARMACEUTICALS INC COM NEW 766559603 17,400 4,793,400 SH   SOLE   4,793,400 0 0
ROCKET PHARMACEUTICALS INC COM 77313F106 12,054 403,270 SH   SOLE   403,270 0 0
SAREPTA THERAPEUTICS INC COM 803607100 32,368 350,000 SH   SOLE   350,000 0 0
SEAGEN INC COM 81181C104 42,450 250,000 SH   SOLE   250,000 0 0
SHATTUCK LABS INC COM 82024L103 6,389 313,499 SH   SOLE   313,499 0 0
SHOCKWAVE MED INC COM 82489T104 45,294 220,000 SH   SOLE   220,000 0 0
SIERRA ONCOLOGY INC COM NEW 82640U404 28,803 1,313,997 SH   SOLE   1,313,997 0 0
SPERO THERAPEUTICS INC COM 84833T103 17,334 941,543 SH   SOLE   941,543 0 0
SPRUCE BIOSCIENCES INC COM 85209E109 9,722 1,617,601 SH   SOLE   1,617,601 0 0
TELEFLEX INCORPORATED COM 879369106 48,952 130,000 SH   SOLE   130,000 0 0
TEMPEST THERAPEUTICS INC COM 87978U108 4,488 310,161 SH   SOLE   310,161 0 0
THERAVANCE BIOPHARMA INC COM G8807B106 5,088 687,500 SH   SOLE   687,500 0 0
THERAVANCE BIOPHARMA INC NOTE 3.250%11/0 88339KAA0 1,391 1,500,000 PRN   SOLE   1,500,000 0 0
TRAVERE THERAPEUTICS INC COM 89422G107 36,298 1,496,817 SH   SOLE   1,496,817 0 0
TRAVERE THERAPEUTICS INC NOTE 2.500% 9/1 761299AB2 3,276 3,250,000 PRN   SOLE   3,250,000 0 0
TRILLIUM THERAPEUTICS INC COM NEW 89620X506 11,036 628,500 SH   SOLE   628,500 0 0
TURMERIC ACQUISITION CORP UNIT 10/08/2025 G9127T116 2,046 206,000 SH   SOLE   206,000 0 0
ULTRAGENYX PHARMACEUTICAL IN COM 90400D108 72,252 801,109 SH   SOLE   801,109 0 0
UNITEDHEALTH GROUP INC COM 91324P102 93,778 240,000 SH   SOLE   240,000 0 0
VERVE THERAPEUTICS INC COM 92539P101 45,253 962,826 SH   SOLE   962,826 0 0
VINCERX PHARMA INC COM NEW 92731L106 12,941 800,295 SH   SOLE   800,295 0 0
WARBY PARKER INC CL A COM 93403J106 34,483 650,000 SH   SOLE   650,000 0 0
WEST PHARMACEUTICAL SVSC INC COM 955306105 12,736 30,000 SH   SOLE   30,000 0 0
XENON PHARMACEUTICALS INC COM 98420N105 8,910 583,100 SH   SOLE   583,100 0 0
ZAI LAB LTD ADR 98887Q104 113,584 1,077,750 SH   SOLE   1,077,750 0 0