The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ACLARIS THERAPEUTICS INC COM 00461U105 4,162 286,226 SH   SOLE   286,226 0 0
AMRYT PHARMA PLC SPONSORED ADS 03217L106 3,782 350,213 SH   SOLE   350,213 0 0
APOLLO ENDOSURGERY INC COM 03767D108 6,235 739,604 SH   SOLE   739,604 0 0
ASLAN PHARMACEUTICALS LTD ADS 04522R101 1,678 1,498,192 SH   SOLE   1,498,192 0 0
AURINIA PHARMACEUTICALS INC COM 05156V102 2,287 100,000 SH   SOLE   100,000 0 0
BELLUS HEALTH INC NEW COM NEW 07987C204 8,855 1,100,000 SH   SOLE   1,100,000 0 0
BENITEC BIOPHARMA INC COM 08205P100 1,539 587,499 SH   SOLE   587,499 0 0
BIOGEN INC COM 09062X103 1,378 5,744 SH   SOLE   5,744 0 0
BIOHAVEN PHARMACTL HLDG CO L COM G11196105 11,073 80,348 SH   SOLE   80,348 0 0
BRIDGEBIO PHARMA INC COM 10806X102 1,668 100,000 SH   SOLE   100,000 0 0
CALITHERA BIOSCIENCES INC COM 13089P101 146 219,791 SH   SOLE   219,791 0 0
CELLDEX THERAPEUTICS INC NEW COM NEW 15117B202 1,744 45,132 SH   SOLE   45,132 0 0
CERUS CORP COM 157085101 7,101 1,042,722 SH   SOLE   1,042,722 0 0
COGENT BIOSCIENCES INC COM 19240Q201 7,301 850,935 SH   SOLE   850,935 0 0
COMPUGEN LTD ORD M25722105 699 162,602 SH   SOLE   162,602 0 0
COMPUGEN LTD ORD M25722105 245 57,000 SH Call SOLE   57,000 0 0
CRINETICS PHARMACEUTICALS IN COM 22663K107 3,178 111,860 SH   SOLE   111,860 0 0
CTI BIOPHARMA CORP COM 12648L601 3,680 1,483,829 SH   SOLE   1,483,829 0 0
CURIS INC COM NEW 231269200 952 200,000 SH Call SOLE   200,000 0 0
CYCLACEL PHARMACEUTICALS INC COM 23254L603 1,783 458,466 SH   SOLE   458,466 0 0
CYTOKINETICS INC COM NEW 23282W605 2,652 58,190 SH   SOLE   58,190 0 0
DECIPHERA PHARMACEUTICALS IN COM 24344T101 1,568 160,526 SH   SOLE   160,526 0 0
ELOXX PHARMACEUTICALS INC COM 29014R103 1,363 1,930,092 SH   SOLE   1,930,092 0 0
EVOGENE LTD SHS M4119S104 481 293,057 SH   SOLE   293,057 0 0
EYEPOINT PHARMACEUTICALS INC COM NEW 30233G209 2,226 181,886 SH   SOLE   181,886 0 0
GALAPAGOS NV SPON ADR 36315X101 7,106 128,901 SH   SOLE   128,901 0 0
HALOZYME THERAPEUTICS INC COM 40637H109 2,855 71,009 SH   SOLE   71,009 0 0
HELIX ACQUISITION CORP COM CL A G4444C102 1,304 131,823 SH   SOLE   131,823 0 0
HORIZON THERAPEUTICS PUB L SHS G46188101 6,649 61,700 SH   SOLE   61,700 0 0
IMMATICS N.V SHS N44445109 5,257 391,155 SH   SOLE   391,155 0 0
IMMUNOGEN INC COM 45253H101 11,237 1,514,411 SH   SOLE   1,514,411 0 0
INHIBRX INC COM 45720L107 1,077 24,666 SH   SOLE   24,666 0 0
INNATE PHARMA S A SPONSORED ADS 45781K204 839 184,046 SH   SOLE   184,046 0 0
INSMED INC COM PAR $.01 457669307 2,741 100,621 SH   SOLE   100,621 0 0
INTRA-CELLULAR THERAPIES INC COM 46116X101 10,206 195,000 SH   SOLE   195,000 0 0
ITEOS THERAPEUTICS INC COM 46565G104 6,426 138,006 SH   SOLE   138,006 0 0
JOUNCE THERAPEUTICS INC COM 481116101 2,053 245,829 SH   SOLE   245,829 0 0
KRYSTAL BIOTECH INC COM 501147102 3,265 46,670 SH   SOLE   46,670 0 0
KURA ONCOLOGY INC COM 50127T109 935 66,812 SH   SOLE   66,812 0 0
LEAP THERAPEUTICS INC COM 52187K101 3,284 1,013,664 SH   SOLE   1,013,664 0 0
LUCIRA HEALTH INC COM 54948U105 4,434 515,000 SH   SOLE   515,000 0 0
MEDICUS SCIENCES ACQUISITION *W EXP 02/12/202 G5960S124 36 49,990 SH   SOLE   49,990 0 0
MEDICUS SCIENCES ACQUISITION CL A SHS G5960S108 1,246 128,582 SH   SOLE   128,582 0 0
MEREO BIOPHARMA GROUP PLC ADS 589492107 373 233,183 SH   SOLE   233,183 0 0
MERUS N V COM N5749R100 10,182 320,174 SH   SOLE   320,174 0 0
MIRATI THERAPEUTICS INC COM 60468T105 8,912 60,757 SH   SOLE   60,757 0 0
MORPHIC HLDG INC COM 61775R105 3,195 67,440 SH   SOLE   67,440 0 0
NEXTCURE INC COM 65343E108 1,158 193,012 SH   SOLE   193,012 0 0
OTONOMY INC COM 68906L105 2,496 1,199,814 SH   SOLE   1,199,814 0 0
POINT BIOPHARMA GLOBAL INC COM 730541109 1,145 204,462 SH   SOLE   204,462 0 0
POLYPID LTD SHS M8001Q118 1,238 215,620 SH   SOLE   215,620 0 0
POSEIDA THERAPEUTICS INC COM 73730P108 1,600 234,932 SH   SOLE   234,932 0 0
RENOVACOR INC *W EXP 99/99/999 75989E114 60 104,828 SH   SOLE   104,828 0 0
RESEARCH ALLIANCE CORP II COM CL A 760873109 5,415 556,890 SH   SOLE   556,890 0 0
SEAGEN INC COM 81181C104 1,677 10,848 SH   SOLE   10,848 0 0
SERES THERAPEUTICS INC COM 81750R102 2,671 320,602 SH   SOLE   320,602 0 0
SIERRA ONCOLOGY INC COM NEW 82640U404 4,175 192,045 SH   SOLE   192,045 0 0
SOCIAL CAP SUVRETTA HLD CRPI CLASS A ORD SHS G8253W109 1,226 123,862 SH   SOLE   123,862 0 0
SOCIAL CAP SUVRETTA HLDS CP CLASS A ORD SHS G8253Y105 1,216 123,862 SH   SOLE   123,862 0 0
SOCIAL CAP SUVRETTA HLDS CRP CLASS A ORD SHS G8253T106 1,230 123,862 SH   SOLE   123,862 0 0
SOCIAL CAP SUVRETTA HLDS CRP CLASS A ORD SHS G8253U103 1,225 123,862 SH   SOLE   123,862 0 0
SPDR SER TR S&P BIOTECH 78464A870 22,392 200,000 SH Call SOLE   200,000 0 0
STEREOTAXIS INC COM NEW 85916J409 2,134 344,236 SH   SOLE   344,236 0 0
SYNDAX PHARMACEUTICALS INC COM 87164F105 2,189 100,000 SH   SOLE   100,000 0 0
UNITED THERAPEUTICS CORP DEL COM 91307C102 3,144 14,551 SH   SOLE   14,551 0 0
VERACYTE INC COM 92337F107 9,120 221,362 SH   SOLE   221,362 0 0
VERTEX PHARMACEUTICALS INC COM 92532F100 1,098 5,000 SH   SOLE   5,000 0 0
VIEWRAY INC COM 92672L107 2,357 427,847 SH   SOLE   427,847 0 0
VIRIDIAN THERAPEUTICS INC COM 92790C104 2,448 123,806 SH   SOLE   123,806 0 0
VISTAGEN THERAPEUTICS INC COM NEW 92840H202 827 424,181 SH   SOLE   424,181 0 0
XENON PHARMACEUTICALS INC COM 98420N105 3,124 100,000 SH   SOLE   100,000 0 0