The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
2SEVENTY BIO ORD COMMON STOCK ADDED 901384107 49,134 1,917,063 SH   SOLE   1,917,063 0 0
5 01 ACQUISITION CORP COM CL A 33836P105 1,970 200,000 SH   SOLE   200,000 0 0
AC IMMUNE SA SHS H00263105 3,710 749,585 SH   SOLE   749,585 0 0
ACADIA PHARMACEUTICALS INC COM 004225108 71,434 3,060,593 SH   SOLE   3,060,593 0 0
ADVERUM BIOTECHNOLOGIES INC COM 00773U108 1,842 1,046,700 SH   SOLE   1,046,700 0 0
AKOUOS INC COM 00973J101 16,796 1,975,984 SH   SOLE   1,975,984 0 0
ALECTOR INC COM 014442107 103,146 4,994,970 SH   SOLE   4,994,970 0 0
ALIGOS THERAPEUTICS INC COM 01626L105 1,081 91,044 SH   SOLE   91,044 0 0
ALNYLAM PHARMACEUTICALS INC COM 02043Q107 16,644 98,146 SH   SOLE   98,146 0 0
ANAPTYSBIO INC COM 032724106 261,356 7,521,024 SH   SOLE   7,521,024 0 0
APELLIS PHARMACEUTICALS INC COM 03753U106 190,722 4,033,882 SH   SOLE   4,033,882 0 0
APPLIED MOLECULAR TRANS INC COM 03824M109 5,592 400,000 SH   SOLE   400,000 0 0
ARCUS BIOSCIENCES INC COM 03969F109 223,530 5,523,358 SH   SOLE   5,523,358 0 0
ARVINAS INC COM 04335A105 10,703 130,300 SH   SOLE   130,300 0 0
ARYA SCIENCES ACQU CORP IV CL A G31659108 1,487 150,000 SH   SOLE   150,000 0 0
ATEA PHARMACEUTICALS INC COM 04683R106 48,063 5,376,134 SH   SOLE   5,376,134 0 0
AVIDITY BIOSCIENCES INC COM 05370A108 65,593 2,759,505 SH   SOLE   2,759,505 0 0
BCLS ACQUISITION CORP COM CL A G0904B105 1,960 200,000 SH   SOLE   200,000 0 0
BOLT BIOTHERAPEUTICS INC COM 097702104 735 150,000 SH   SOLE   150,000 0 0
C4 THERAPEUTICS INC COM STK 12529R107 6,440 200,000 SH   SOLE   200,000 0 0
CAREMAX INC *W EXP 06/08/202 14171W111 768 100,000 SH   SOLE   100,000 0 0
CARIBOU BIOSCIENCES INC COM 142038108 1,132 75,000 SH   SOLE   75,000 0 0
CENTESSA PHARMACEUTICALS PLC SPONSORED ADS 152309100 9,933 882,176 SH   SOLE   882,176 0 0
CRINETICS PHARMACEUTICALS IN COM 22663K107 16,767 590,169 SH   SOLE   590,169 0 0
CRISPR THERAPEUTICS AG NAMEN AKT H17182108 81,652 1,077,483 SH   SOLE   1,077,483 0 0
DESIGN THERAPEUTICS INC COM 25056L103 46,096 2,152,997 SH   SOLE   2,152,997 0 0
DYNE THERAPEUTICS INC COM 26818M108 2,556 215,000 SH   SOLE   215,000 0 0
EDGEWISE THERAPEUTICS INC COM 28036F105 19,546 1,279,175 SH   SOLE   1,279,175 0 0
ERASCA INC COM 29479A108 10,906 700,000 SH   SOLE   700,000 0 0
EUCRATES BIOMEDICAL ACQU COR SHS G3141W106 1,952 200,000 SH   SOLE   200,000 0 0
EUCRATES BIOMEDICAL ACQU COR *W EXP 10/23/202 G3141W122 651 66,666 SH   SOLE   66,666 0 0
FRAZIER LIFESCIENCES ACQU CO *W EXP 11/30/202 G3710A113 650 66,665 SH   SOLE   66,665 0 0
FRAZIER LIFESCIENCES ACQU CO SHS G3710A105 5,729 587,615 SH   SOLE   587,615 0 0
GALAPAGOS NV SPON ADR 36315X101 122,631 2,224,403 SH   SOLE   2,224,403 0 0
GRAPHITE BIO INC COM 38870X104 8,563 688,900 SH   SOLE   688,900 0 0
GRITSTONE BIO INC COM 39868T105 77,317 6,012,232 SH   SOLE   6,012,232 0 0
GRITSTONE BIO INC COM 39868T105 3,948 307,000 SH Call SOLE   307,000 0 0
HALOZYME THERAPEUTICS INC COM 40637H109 15,762 392,000 SH   SOLE   392,000 0 0
HEALTH SCIENCES ACQ CORP 2 ORD SHS G4411D109 4,032 400,000 SH   SOLE   400,000 0 0
HELIX ACQUISITION CORP COM CL A G4444C102 1,978 200,000 SH   SOLE   200,000 0 0
IMMUNOVANT INC COM 45258J102 9,720 1,140,819 SH   SOLE   1,140,819 0 0
ITEOS THERAPEUTICS INC COM 46565G104 60,675 1,303,157 SH   SOLE   1,303,157 0 0
JANUX THERAPEUTICS INC COM 47103J105 27,858 1,411,975 SH   SOLE   1,411,975 0 0
JIYA ACQUISITION CORP COM CL A 47760M102 4,885 500,000 SH   SOLE   500,000 0 0
KINNATE BIOPHARMA INC COM 49705R105 3,101 175,000 SH   SOLE   175,000 0 0
KRONOS BIO INC COM 50107A104 5,264 387,357 SH   SOLE   387,357 0 0
KURA ONCOLOGY INC COM 50127T109 52,142 3,724,437 SH   SOLE   3,724,437 0 0
LEGEND BIOTECH CORP SPONSORED ADS 52490G102 14,337 307,594 SH   SOLE   307,594 0 0
MONTE ROSA THERAPEUTICS INC COM 61225M102 768 37,593 SH   SOLE   37,593 0 0
MORPHIC HLDG INC COM 61775R105 187,225 3,951,566 SH   SOLE   3,951,566 0 0
NEOLEUKIN THERAPEUTICS INC COM 64049K104 4,148 860,619 SH   SOLE   860,619 0 0
NURIX THERAPEUTICS INC COM 67080M103 8,961 309,540 SH   SOLE   309,540 0 0
NUVATION BIO INC *W EXP 07/07/202 67080N119 8,188 963,333 SH   SOLE   963,333 0 0
NUVATION BIO INC COM CL A 67080N101 118,121 13,896,543 SH   SOLE   13,896,543 0 0
OMEGA ALPHA SPAC CL A G6749V107 489 50,000 SH   SOLE   50,000 0 0
ORIC PHARMACEUTICALS INC COM 68622P109 50,993 3,468,944 SH   SOLE   3,468,944 0 0
OVID THERAPEUTICS INC COM 690469101 19,524 6,082,200 SH   SOLE   6,082,200 0 0
PARDES BIOSCIENCES ORD COM ADDED 69945Q105 26,145 1,597,139 SH   SOLE   1,597,139 0 0
PMV PHARMACEUTICALS INC COM 69353Y103 1,155 50,000 SH   SOLE   50,000 0 0
PROTAGONIST THERAPEUTICS INC COM 74366E102 90,278 2,639,706 SH   SOLE   2,639,706 0 0
PROTHENA CORP PLC SHS G72800108 557,443 11,284,280 SH   SOLE   11,284,280 0 0
RELAY THERAPEUTICS INC COM 75943R102 54,636 1,779,084 SH   SOLE   1,779,084 0 0
REPARE THERAPEUTICS INC COM 760273102 1,055 50,000 SH   SOLE   50,000 0 0
SAGE THERAPEUTICS INC COM 78667J108 40,015 940,636 SH   SOLE   940,636 0 0
SILVERBACK THERAPEUTICS INC COM 82835W108 7,060 1,060,010 SH   SOLE   1,060,010 0 0
SOLID BIOSCIENCES INC COM 83422E105 16,105 9,202,702 SH   SOLE   9,202,702 0 0
SURROZEN INC COM 86889P117 429 66,665 SH   SOLE   66,665 0 0
TANGO THERAPEUTICS INC COM 87583X109 14,222 1,300,000 SH   SOLE   1,300,000 0 0
TURMERIC ACQUISITION CORP CL A G9127T108 982 100,000 SH   SOLE   100,000 0 0
TURMERIC ACQUISITION CORP *W EXP 10/08/202 G9127T124 327 33,333 SH   SOLE   33,333 0 0
VAXCYTE INC COM 92243G108 495 20,800 SH   SOLE   20,800 0 0
VENTYX BIOSCIENCES ORD COM ADDED 92332V107 25,818 1,300,000 SH   SOLE   1,300,000 0 0
VERVE THERAPEUTICS INC COM 92539P101 3,687 100,000 SH   SOLE   100,000 0 0
VOYAGER THERAPEUTICS INC COM 92915B106 9,641 3,557,507 SH   SOLE   3,557,507 0 0
VTV THERAPEUTICS INC CL A 918385105 830 834,333 SH   SOLE   834,333 0 0
XENCOR INC COM 98401F105 196,833 4,906,106 SH   SOLE   4,906,106 0 0