The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
AADI BIOSCIENCE INC COM 00032Q104 13,013 538,835 SH   SOLE   538,835 0 0
ABCAM PLC ADS 000380204 29,496 1,252,500 SH   SOLE   1,252,500 0 0
ACADIA HEALTHCARE COMPANY IN COM 00404A109 45,434 748,500 SH   SOLE   748,500 0 0
ACCOLADE INC COM 00437E102 31,553 1,197,000 SH   SOLE   1,197,000 0 0
ACELRX PHARMACEUTICALS INC COM 00444T100 3,544 6,325,902 SH   SOLE   6,325,902 0 0
ACLARIS THERAPEUTICS INC COM 00461U105 56,144 3,861,347 SH   SOLE   3,861,347 0 0
ACUMEN PHARMACEUTICALS INC COM 00509G209 10,626 1,571,918 SH   SOLE   1,571,918 0 0
ADAPTIMMUNE THERAPEUTICS PLC SPONDS ADR 00653A107 8,308 2,215,588 SH   SOLE   2,215,588 0 0
AEGLEA BIOTHERAPEUTICS INC COM 00773J103 7,492 1,577,296 SH   SOLE   1,577,296 0 0
AGILON HEALTH INC COM 00857U107 202,365 7,495,000 SH   SOLE   7,495,000 0 0
AGIOS PHARMACEUTICALS INC COM 00847X104 86,995 2,646,625 SH   SOLE   2,646,625 0 0
AKERO THERAPEUTICS INC COM 00973Y108 12,417 587,101 SH   SOLE   587,101 0 0
ALIGN TECHNOLOGY INC COM 016255101 131,436 200,000 SH   SOLE   200,000 0 0
ALNYLAM PHARMACEUTICALS INC COM 02043Q107 56,385 332,500 SH   SOLE   332,500 0 0
AMARIN CORP PLC SPONS ADR NEW 023111206 14,894 4,419,700 SH   SOLE   4,419,700 0 0
AMICUS THERAPEUTICS INC COM 03152W109 11,694 1,012,506 SH   SOLE   1,012,506 0 0
AMRYT PHARMA PLC SPONSORED ADS 03217L106 14,103 1,305,825 SH   SOLE   1,305,825 0 0
ANAPTYSBIO INC COM 032724106 18,720 538,700 SH   SOLE   538,700 0 0
APPLIED THERAPEUTICS INC COM 03828A101 6,280 701,680 SH   SOLE   701,680 0 0
ARGENX SE SPONSORED ADR 04016X101 110,310 315,000 SH   SOLE   315,000 0 0
ARVINAS INC COM 04335A105 37,554 457,200 SH   SOLE   457,200 0 0
ASCENDIS PHARMA A/S SPONSORED ADR 04351P101 53,812 400,000 SH   SOLE   400,000 0 0
ATHIRA PHARMA INC COM 04746L104 7,196 552,252 SH   SOLE   552,252 0 0
ATRECA INC CL A COM 04965G109 1,401 462,530 SH   SOLE   462,530 0 0
AURA BIOSCIENCES INC COM 05153U107 17,118 1,008,114 SH   SOLE   1,008,114 0 0
AURINIA PHARMACEUTICALS INC COM 05156V102 10,456 457,173 SH   SOLE   457,173 0 0
BAXTER INTL INC COM 071813109 62,990 733,803 SH   SOLE   733,803 0 0
BCLS ACQUISITION CORP COM CL A G0904B105 3,028 309,000 SH   SOLE   309,000 0 0
BIOMARIN PHARMACEUTICAL INC COM 09061G101 23,324 264,000 SH   SOLE   264,000 0 0
BIOMEA FUSION INC COM 09077A106 8,684 1,165,582 SH   SOLE   1,165,582 0 0
BLUEPRINT MEDICINES CORP COM 09627Y109 92,088 859,755 SH   SOLE   859,755 0 0
CEREVEL THERAPEUTICS HLDNG I COM 15678U128 53,442 1,648,435 SH   SOLE   1,648,435 0 0
CHINOOK THERAPEUTICS INC COM 16961L106 11,749 720,349 SH   SOLE   720,349 0 0
COLLEGIUM PHARMACEUTICAL INC COM 19459J104 13,543 725,000 SH   SOLE   725,000 0 0
COMPASS THERAPEUTICS INC COM 20454B104 16,890 5,328,088 SH   SOLE   5,328,088 0 0
COMPUGEN LTD ORD M25722105 5,547 1,289,990 SH   SOLE   1,289,990 0 0
CONMED CORP COM 207410101 28,706 202,500 SH   SOLE   202,500 0 0
COVETRUS INC COM 22304C100 33,184 1,661,700 SH   SOLE   1,661,700 0 0
CULLINAN ONCOLOGY INC COM 230031106 9,969 646,078 SH   SOLE   646,078 0 0
CYTOKINETICS INC NOTE 4.000%11/1 23282WAA8 35,665 8,000,000 PRN   SOLE   8,000,000 0 0
DAY ONE BIOPHARMACEUTICALS I COM 23954D109 6,436 381,939 SH   SOLE   381,939 0 0
DESIGN THERAPEUTICS INC COM 25056L103 7,178 335,247 SH   SOLE   335,247 0 0
DEXCOM INC COM 252131107 30,472 56,750 SH   SOLE   56,750 0 0
DYNAVAX TECHNOLOGIES CORP COM NEW 268158201 22,187 1,576,894 SH   SOLE   1,576,894 0 0
EDAP TMS S A SPONSORED ADR 268311107 4,558 760,900 SH   SOLE   760,900 0 0
EDWARDS LIFESCIENCES CORP COM 28176E108 75,398 582,000 SH   SOLE   582,000 0 0
ENCOMPASS HEALTH CORP COM 29261A100 32,793 502,500 SH   SOLE   502,500 0 0
EPIZYME INC COM 29428V104 9,519 3,807,662 SH   SOLE   3,807,662 0 0
ESSA PHARMA INC COM NEW 29668H708 7,257 511,044 SH   SOLE   511,044 0 0
EVOLENT HEALTH INC CL A 30050B101 56,391 2,038,000 SH   SOLE   2,038,000 0 0
EXACT SCIENCES CORP COM 30063P105 44,363 570,000 SH   SOLE   570,000 0 0
FATE THERAPEUTICS INC COM 31189P102 6,436 110,000 SH   SOLE   110,000 0 0
FRESHPET INC COM 358039105 55,257 580,000 SH   SOLE   580,000 0 0
F-STAR THERAPEUTICS INC COM 30315R107 3,774 751,889 SH   SOLE   751,889 0 0
FULCRUM THERAPEUTICS INC COM 359616109 8,084 456,990 SH   SOLE   456,990 0 0
FUSION PHARMACEUTICALS INC COM 36118A100 3,955 948,327 SH   SOLE   948,327 0 0
GAMIDA CELL LTD SHS M47364100 5,472 2,154,300 SH   SOLE   2,154,300 0 0
GOSSAMER BIO INC NOTE 5.000% 6/0 38341PAA0 15,066 15,373,000 PRN   SOLE   15,373,000 0 0
GRAPHITE BIO INC COM 38870X104 25,841 2,078,910 SH   SOLE   2,078,910 0 0
GUARDANT HEALTH INC COM 40131M109 20,004 200,000 SH   SOLE   200,000 0 0
HCA HEALTHCARE INC COM 40412C101 115,614 450,000 SH   SOLE   450,000 0 0
HEALTH CATALYST INC COM 42225T107 33,685 850,200 SH   SOLE   850,200 0 0
HORIZON THERAPEUTICS PUB L SHS G46188101 80,389 746,000 SH   SOLE   746,000 0 0
HUMANA INC COM 444859102 161,887 349,000 SH   SOLE   349,000 0 0
ICOSAVAX INC COM 45114M109 16,828 735,504 SH   SOLE   735,504 0 0
IDEXX LABS INC COM 45168D104 118,523 180,000 SH   SOLE   180,000 0 0
IMARA INC COM 45249V107 1,895 842,302 SH   SOLE   842,302 0 0
IMMUNEERING CORP CLASS A COM 45254E107 17,622 1,089,816 SH   SOLE   1,089,816 0 0
IMMUNOCORE HLDGS PLC ADS 45258D105 84,626 2,471,555 SH   SOLE   2,471,555 0 0
INOZYME PHARMA INC COM 45790W108 5,923 868,466 SH   SOLE   868,466 0 0
INSULET CORP COM 45784P101 123,390 463,750 SH   SOLE   463,750 0 0
INTERSECT ENT INC COM 46071F103 25,671 940,000 SH   SOLE   940,000 0 0
INTUITIVE SURGICAL INC COM NEW 46120E602 129,348 360,000 SH   SOLE   360,000 0 0
INVITAE CORP COM 46185L103 42,760 2,800,243 SH   SOLE   2,800,243 0 0
IRHYTHM TECHNOLOGIES INC COM 450056106 50,960 433,000 SH   SOLE   433,000 0 0
JIYA ACQUISITION CORP COM CL A 47760M102 2,015 206,200 SH   SOLE   206,200 0 0
KARUNA THERAPEUTICS INC COM 48576A100 55,916 426,843 SH   SOLE   426,843 0 0
KINNATE BIOPHARMA INC COM 49705R105 6,022 339,846 SH   SOLE   339,846 0 0
KYMERA THERAPEUTICS INC COM 501575104 47,114 742,065 SH   SOLE   742,065 0 0
LEAP THERAPEUTICS INC COM 52187K101 11,407 3,520,570 SH   SOLE   3,520,570 0 0
LEGEND BIOTECH CORP SPONSORED ADS 52490G102 18,811 403,584 SH   SOLE   403,584 0 0
LIFESTANCE HEALTH GROUP INC COM 53228F101 19,040 2,000,000 SH   SOLE   2,000,000 0 0
MACROGENICS INC COM 556099109 13,758 857,205 SH   SOLE   857,205 0 0
MADRIGAL PHARMACEUTICALS INC COM 558868105 22,829 269,400 SH   SOLE   269,400 0 0
MEREO BIOPHARMA GROUP PLC ADS 589492107 8,937 5,585,621 SH   SOLE   5,585,621 0 0
MERSANA THERAPEUTICS INC COM 59045L106 20,208 3,248,950 SH   SOLE   3,248,950 0 0
MIRATI THERAPEUTICS INC COM 60468T105 60,204 410,415 SH   SOLE   410,415 0 0
MIRUM PHARMACEUTICALS INC COM 604749101 24,544 1,538,814 SH   SOLE   1,538,814 0 0
NEUROCRINE BIOSCIENCES INC COM 64125C109 94,113 1,105,000 SH   SOLE   1,105,000 0 0
NEUROCRINE BIOSCIENCES INC NOTE 2.250% 5/1 64125CAD1 1,257 1,000,000 PRN   SOLE   1,000,000 0 0
NEVRO CORP COM 64157F103 57,884 714,000 SH   SOLE   714,000 0 0
NEVRO CORP NOTE 2.750% 4/0 64157FAC7 556 500,000 PRN   SOLE   500,000 0 0
NKARTA INC COM 65487U108 7,786 507,248 SH   SOLE   507,248 0 0
NOVAVAX INC COM NEW 670002401 60,805 425,000 SH   SOLE   425,000 0 0
NOVOCURE LTD ORD SHS G6674U108 13,139 175,000 SH   SOLE   175,000 0 0
NURIX THERAPEUTICS INC COM 67080M103 9,294 321,050 SH   SOLE   321,050 0 0
NUVATION BIO INC *W EXP 07/07/202 67080N119 253 134,028 SH   SOLE   134,028 0 0
OLINK HLDG AB SPONSORED ADS 680710100 9,373 515,000 SH   SOLE   515,000 0 0
ORION ACQUISITION CORP UNIT 02/19/2026 68626A207 9,850 1,000,000 SH   SOLE   1,000,000 0 0
PACIRA BIOSCIENCES INC COM 695127100 60,170 1,000,000 SH   SOLE   1,000,000 0 0
PACIRA BIOSCIENCES INC NOTE 2.375% 4/0 695127AD2 1,029 1,000,000 PRN   SOLE   1,000,000 0 0
PARATEK PHARMACEUTICALS INC COM 699374302 7,620 1,697,105 SH   SOLE   1,697,105 0 0
PENUMBRA INC COM 70975L107 42,667 148,500 SH   SOLE   148,500 0 0
PHASEBIO PHARMACEUTICALS INC COM 717224109 6,737 2,581,299 SH   SOLE   2,581,299 0 0
PHREESIA INC COM 71944F106 32,078 770,000 SH   SOLE   770,000 0 0
POSEIDA THERAPEUTICS INC COM 73730P108 1,973 289,754 SH   SOLE   289,754 0 0
PRELUDE THERAPEUTICS INC COM 74065P101 4,594 368,959 SH   SOLE   368,959 0 0
PROMETHEUS BIOSCIENCES INC COM 74349U108 24,452 618,407 SH   SOLE   618,407 0 0
PROTHENA CORP PLC SHS G72800108 31,998 647,730 SH   SOLE   647,730 0 0
PULMONX CORP COM 745848101 22,449 700,000 SH   SOLE   700,000 0 0
RADIUS HEALTH INC NOTE 3.000% 9/0 750469AA6 1,459 1,500,000 PRN   SOLE   1,500,000 0 0
RELAY THERAPEUTICS INC COM 75943R102 18,357 597,767 SH   SOLE   597,767 0 0
RENEO PHARMACEUTICALS INC COM 75974E103 9,774 1,143,185 SH   SOLE   1,143,185 0 0
RHYTHM PHARMACEUTICALS INC COM 76243J105 6,259 627,180 SH   SOLE   627,180 0 0
RIGEL PHARMACEUTICALS INC COM NEW 766559603 12,880 4,860,200 SH   SOLE   4,860,200 0 0
SAREPTA THERAPEUTICS INC COM 803607100 38,181 424,000 SH   SOLE   424,000 0 0
SEAGEN INC COM 81181C104 39,578 256,000 SH   SOLE   256,000 0 0
SHATTUCK LABS INC COM 82024L103 2,668 313,499 SH   SOLE   313,499 0 0
SHOCKWAVE MED INC COM 82489T104 39,678 222,500 SH   SOLE   222,500 0 0
SIERRA ONCOLOGY INC COM NEW 82640U404 25,757 1,184,793 SH   SOLE   1,184,793 0 0
SPERO THERAPEUTICS INC COM 84833T103 15,134 945,313 SH   SOLE   945,313 0 0
SPRUCE BIOSCIENCES INC COM 85209E109 7,237 1,622,689 SH   SOLE   1,622,689 0 0
TEMPEST THERAPEUTICS INC COM 87978U108 4,349 823,654 SH   SOLE   823,654 0 0
THERAVANCE BIOPHARMA INC NOTE 3.250%11/0 88339KAA0 1,456 1,500,000 PRN   SOLE   1,500,000 0 0
THESEUS PHARMACEUTICALS INC COM 88369M101 5,545 437,329 SH   SOLE   437,329 0 0
TRAVERE THERAPEUTICS INC COM 89422G107 29,539 951,650 SH   SOLE   951,650 0 0
TRAVERE THERAPEUTICS INC NOTE 2.500% 9/1 761299AB2 3,589 3,250,000 PRN   SOLE   3,250,000 0 0
ULTRAGENYX PHARMACEUTICAL IN COM 90400D108 74,329 883,921 SH   SOLE   883,921 0 0
UNITEDHEALTH GROUP INC COM 91324P102 120,514 240,000 SH   SOLE   240,000 0 0
VERVE THERAPEUTICS INC COM 92539P101 33,291 902,926 SH   SOLE   902,926 0 0
VINCERX PHARMA INC COM NEW 92731L106 8,246 809,195 SH   SOLE   809,195 0 0
WARBY PARKER INC CL A COM 93403J106 33,709 724,000 SH   SOLE   724,000 0 0
WEST PHARMACEUTICAL SVSC INC COM 955306105 21,340 45,500 SH   SOLE   45,500 0 0
XENON PHARMACEUTICALS INC COM 98420N105 24,098 771,367 SH   SOLE   771,367 0 0
XILIO THERAPEUTICS INC COM 98422T100 19,058 1,191,094 SH   SOLE   1,191,094 0 0
ZAI LAB LTD ADR 98887Q104 74,207 1,180,700 SH   SOLE   1,180,700 0 0