The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
1Life Healthcare, Inc. Common 68269G107 549 31,266 SH   SOLE   31,266 0 0
Abbott Laboratories Common 002824100 82,090 583,277 SH   SOLE   583,277 0 0
AbbVie Inc. Common 00287Y109 69,029 509,817 SH   SOLE   509,817 0 0
ACADIA Pharmaceuticals Inc. Common 004225108 1,686 72,225 SH   SOLE   72,225 0 0
Adaptive Biotechnologies Corp. Common 00650F109 9,476 337,722 SH   SOLE   337,722 0 0
Addus HomeCare Corp. Common 006739106 7,820 83,632 SH   SOLE   83,632 0 0
Adicet Bio, Inc. Common 007002108 1,108 63,329 SH   SOLE   63,329 0 0
Affimed N.V. Common N01045108 3,235 586,038 SH   SOLE   586,038 0 0
Agilent Technologies Inc. Common 00846U101 6,326 39,625 SH   SOLE   39,625 0 0
Align Technology, Inc. Common 016255101 4,902 7,459 SH   SOLE   7,459 0 0
Alkermes plc Shares G01767105 6,450 277,309 SH   SOLE   277,309 0 0
Alnylam Pharmaceuticals, Inc. Common 02043Q107 32,168 189,695 SH   SOLE   189,695 0 0
ALX Oncology Holdings Inc. Common 00166B105 1,423 66,211 SH   SOLE   66,211 0 0
Amgen Inc. Common 031162100 129,339 574,918 SH   SOLE   574,918 0 0
AMN Healthcare Services, Inc. Common 001744101 7,487 61,201 SH   SOLE   61,201 0 0
Anthem, Inc. Common 036752103 6,788 14,644 SH   SOLE   14,644 0 0
Apellis Pharmaceuticals, Inc. Common 03753U106 9,258 195,820 SH   SOLE   195,820 0 0
ARCA biopharma, Inc. Common 00211Y506 70 32,461 SH   SOLE   32,461 0 0
Arcutis Biotherapeutics, Inc. Common 03969K108 2,730 131,633 SH   SOLE   131,633 0 0
Ardelyx, Inc. Common 039697107 593 539,408 SH   SOLE   539,408 0 0
Arena Pharmaceuticals, Inc. Common 040047607 16,355 175,976 SH   SOLE   175,976 0 0
argenx SE Sponsored ADR 04016X101 13,467 38,456 SH   SOLE   38,456 0 0
Arrowhead Pharmaceuticals, Inc. Common 04280A100 8,938 134,812 SH   SOLE   134,812 0 0
Arvinas, Inc. Common 04335A105 7,064 85,997 SH   SOLE   85,997 0 0
Ascendis Pharma A/S Sponsored ADR 04351P101 9,120 67,794 SH   SOLE   67,794 0 0
Assertio Holdings, Inc. Common 04546C205 895 410,575 SH   SOLE   410,575 0 0
Astellas Pharma Inc. Common 698538006 1,445 88,837 SH   SOLE   88,837 0 0
AstraZeneca PLC Sponsored ADR 046353108 45,871 787,485 SH   SOLE   787,485 0 0
Aurinia Pharmaceuticals Inc. Common 05156V102 3,719 162,599 SH   SOLE   162,599 0 0
Beam Therapeutics Inc. Common 07373V105 1,260 15,817 SH   SOLE   15,817 0 0
Becton, Dickinson and Co. Common 075887109 10,891 43,307 SH   SOLE   43,307 0 0
BeiGene, Ltd. Sponsored ADR 07725L102 17,278 63,772 SH   SOLE   63,772 0 0
Bellicum Pharmaceuticals, Inc. Common 079481404 9 6,000 SH   SOLE   6,000 0 0
Biogen Inc. Common 09062X103 32,543 135,639 SH   SOLE   135,639 0 0
Biohaven Pharmaceutical Holding Co. Ltd. Common G11196105 9,671 70,176 SH   SOLE   70,176 0 0
BioMarin Pharmaceutical Inc. Common 09061G101 11,309 128,004 SH   SOLE   128,004 0 0
BioNTech SE Sponsored ADS 09075V102 23,264 90,242 SH   SOLE   90,242 0 0
Black Diamond Therapeutics, Inc. Common 09203E105 704 131,990 SH   SOLE   131,990 0 0
Boston Scientific Corp. Common 101137107 22,771 536,042 SH   SOLE   536,042 0 0
Bristol-Myers Squibb Co. Common 110122108 46,578 747,043 SH   SOLE   747,043 0 0
Caribou Biosciences, Inc. Common 142038108 9,875 699,377 SH   SOLE   699,377 0 0
Cerevel Therapeutics Holdings, Inc. Common 15678U128 1,329 41,003 SH   SOLE   41,003 0 0
Charles River Laboratories International, Inc. Common 159864107 23,357 61,990 SH   SOLE   61,990 0 0
ChemoCentryx, Inc. Common 16383L106 2,847 78,197 SH   SOLE   78,197 0 0
Cigna Corp. Common 125523100 32,934 143,423 SH   SOLE   143,423 0 0
Community Health Systems, Inc. Common 203668108 1,176 88,335 SH   SOLE   88,335 0 0
Community Healthcare Trust Inc. Common 20369C106 704 14,900 SH   SOLE   14,900 0 0
Corbus Pharmaceuticals Holdings, Inc. Common 21833P103 95 154,310 SH   SOLE   154,310 0 0
CRISPR Therapeutics AG Namen AKT H17182108 4,174 55,080 SH   SOLE   55,080 0 0
CVS Health Corp. Common 126650100 15,211 147,453 SH   SOLE   147,453 0 0
Cytokinetics, Inc. Common 23282W605 4,233 92,871 SH   SOLE   92,871 0 0
Danaher Corp. Common 235851102 66,578 202,360 SH   SOLE   202,360 0 0
Denali Therapeutics Inc. Common 24823R105 9,920 222,420 SH   SOLE   222,420 0 0
DENTSPLY SIRONA Inc. Common 24906P109 3,202 57,400 SH   SOLE   57,400 0 0
Design Therapeutics, Inc. Common 25056L103 1,399 65,351 SH   SOLE   65,351 0 0
Dexcom, Inc. Common 252131107 22,515 41,931 SH   SOLE   41,931 0 0
Diversified Healthcare Trust Common 25525P107 1,105 357,720 SH   SOLE   357,720 0 0
Edgewise Therapeutics, Inc. Common 28036F105 925 60,550 SH   SOLE   60,550 0 0
Edwards Lifesciences Corp. Common 28176E108 22,955 177,188 SH   SOLE   177,188 0 0
Eli Lilly and Co. Common 532457108 63,650 230,432 SH   SOLE   230,432 0 0
Endo International plc Shares G30401106 1,860 494,607 SH   SOLE   494,607 0 0
Fate Therapeutics, Inc. Common 31189P102 4,255 72,727 SH   SOLE   72,727 0 0
Five Star Senior Living Inc. Common 33832D205 71 24,237 SH   SOLE   24,237 0 0
Forma Therapeutics Holdings, Inc. Shares 34633R104 756 53,186 SH   SOLE   53,186 0 0
Fulcrum Therapeutics, Inc. Common 359616109 1,367 77,293 SH   SOLE   77,293 0 0
Fusion Pharmaceuticals Inc. Common 36118A100 181 43,394 SH   SOLE   43,394 0 0
G1 Therapeutics, Inc. Common 3621LQ109 4,328 423,869 SH   SOLE   423,869 0 0
Galera Therapeutics, Inc. Common 36338D108 4,124 898,374 SH   SOLE   898,374 0 0
Gilead Sciences, Inc. Common 375558103 122,461 1,686,565 SH   SOLE   1,686,565 0 0
Global Medical REIT Inc. Common 37954A204 3,104 174,897 SH   SOLE   174,897 0 0
Guardant Health, Inc. Common 40131M109 35,155 351,484 SH   SOLE   351,484 0 0
HCA Healthcare, Inc. Common 40412C101 28,765 111,961 SH   SOLE   111,961 0 0
Health Care Select Sector SPDR Fund SBI Healthcare 81369Y209 15,953 113,230 SH   SOLE   113,230 0 0
Healthcare Realty Trust Inc. Common 421946104 3,291 104,024 SH   SOLE   104,024 0 0
Healthcare Trust of America, Inc. Common 42225P501 2,359 70,662 SH   SOLE   70,662 0 0
Healthpeak Properties, Inc. Common 42250P103 5,428 150,392 SH   SOLE   150,392 0 0
Helix Acquisition Corp. Class A G4444C102 2,473 250,000 SH   SOLE   250,000 0 0
Hologic, Inc. Common 436440101 2,170 28,347 SH   SOLE   28,347 0 0
Horizon Therapeutics plc Shares G46188101 96,719 897,540 SH   SOLE   897,540 0 0
Humana Inc. Common 444859102 32,312 69,660 SH   SOLE   69,660 0 0
I-Mab Sponsored ADS 44975P103 7,705 162,580 SH   SOLE   162,580 0 0
Icon plc Shares G4705A100 30,620 98,871 SH   SOLE   98,871 0 0
IDEAYA Biosciences, Inc. Common 45166A102 484 20,454 SH   SOLE   20,454 0 0
IDEXX Laboratories, Inc. Common 45168D104 52,455 79,663 SH   SOLE   79,663 0 0
Illumina, Inc. Common 452327109 86,060 226,212 SH   SOLE   226,212 0 0
Intellia Therapeutics, Inc. Common 45826J105 6,879 58,180 SH   SOLE   58,180 0 0
Intercept Pharmaceuticals, Inc. Common 45845P108 848 52,067 SH   SOLE   52,067 0 0
Intra-Cellular Therapies, Inc. Common 46116X101 12,376 236,447 SH   SOLE   236,447 0 0
Intuitive Surgical, Inc. Common 46120E602 20,698 57,606 SH   SOLE   57,606 0 0
Ionis Pharmaceuticals, Inc. Common 462222100 5,346 175,680 SH   SOLE   175,680 0 0
IQVIA Holdings Inc. Common 46266C105 27,693 98,154 SH   SOLE   98,154 0 0
iTeos Therapeutics, Inc. Common 46565G104 1,972 42,362 SH   SOLE   42,362 0 0
Jazz Pharmaceuticals plc Shares G50871105 14,946 117,315 SH   SOLE   117,315 0 0
Johnson & Johnson Common 478160104 88,384 516,652 SH   SOLE   516,652 0 0
KalVista Pharmaceuticals, Inc. Common 483497103 418 31,594 SH   SOLE   31,594 0 0
Karuna Therapeutics, Inc. Common 48576A100 13,160 100,458 SH   SOLE   100,458 0 0
Kodiak Sciences Inc. Common 50015M109 723 8,530 SH   SOLE   8,530 0 0
Koninklijke Philips N.V. NY Reg Shares 500472303 6,073 164,790 SH   SOLE   164,790 0 0
Laboratory Corporation of America Holdings Sponsored ADR 50540R409 13,870 44,142 SH   SOLE   44,142 0 0
LTC Properties, Inc. Common 502175102 6,223 182,293 SH   SOLE   182,293 0 0
McKesson Corp. Common 58155Q103 46,861 188,522 SH   SOLE   188,522 0 0
Medical Properties Trust, Inc. Common 58463J304 9,729 411,743 SH   SOLE   411,743 0 0
Medpace Holdings, Inc. Common 58506Q109 4,107 18,871 SH   SOLE   18,871 0 0
Medtronic plc Shares G5960L103 52,331 505,860 SH   SOLE   505,860 0 0
Merck & Co., Inc. Common 58933Y105 60,402 788,122 SH   SOLE   788,122 0 0
Mereo BioPharma Group plc ADS 589492107 2,482 1,551,082 SH   SOLE   1,551,082 0 0
Merus N.V. Common N5749R100 1,331 41,857 SH   SOLE   41,857 0 0
Mettler-Toledo International Inc. Common 592688105 11,286 6,650 SH   SOLE   6,650 0 0
Mirati Therapeutics, Inc. Common 60468T105 12,290 83,784 SH   SOLE   83,784 0 0
Moderna, Inc. Common 60770K107 138,832 546,624 SH   SOLE   546,624 0 0
Molina Healthcare, Inc. Common 60855R100 31,275 98,325 SH   SOLE   98,325 0 0
Morphic Holding, Inc. Common 61775R105 1,659 35,025 SH   SOLE   35,025 0 0
MorphoSys AG Sponsored ADS 617760202 771 81,867 SH   SOLE   81,867 0 0
National Health Investors, Inc. Common 63633D104 577 10,038 SH   SOLE   10,038 0 0
Neurocrine Biosciences, Inc. Common 64125C109 10,613 124,609 SH   SOLE   124,609 0 0
Nexgel Common 935LTY900 11 4,243 SH   SOLE   4,243 0 0
Nkarta, Inc. Common 65487U108 445 28,988 SH   SOLE   28,988 0 0
Novartis AG Sponsored ADR 66987V109 11,916 136,225 SH   SOLE   136,225 0 0
Novavax, Inc. Common 670002401 9,128 63,800 SH   SOLE   63,800 0 0
Novo Nordisk A/S Sponsored ADR 670100205 13,255 118,349 SH   SOLE   118,349 0 0
Omega Healthcare Investors, Inc. Common 681936100 9,067 306,433 SH   SOLE   306,433 0 0
Owens & Minor, Inc. Common 690732102 12,535 288,167 SH   SOLE   288,167 0 0
PerkinElmer, Inc. Common 714046109 6,724 33,444 SH   SOLE   33,444 0 0
Perrigo Co. plc Shares G97822103 1,993 51,224 SH   SOLE   51,224 0 0
Pfizer Inc. Common 717081103 69,201 1,171,903 SH   SOLE   1,171,903 0 0
Physicians Realty Trust Common 71943U104 9,335 495,733 SH   SOLE   495,733 0 0
Praxis Precision Medicines, Inc. Common 74006W108 1,478 75,000 SH   SOLE   75,000 0 0
Precision BioSciences, Inc. Common 74019P108 1,662 224,534 SH   SOLE   224,534 0 0
Protagonist Therapeutics, Inc. Common 74366E102 3,455 101,037 SH   SOLE   101,037 0 0
Pyxis Oncology, Inc. Common 747324101 1,481 135,000 SH   SOLE   135,000 0 0
Qiagen N.V. Shares N72482123 5,995 107,855 SH   SOLE   107,855 0 0
R1 RCM Inc. Common 749397105 5,158 202,351 SH   SOLE   202,351 0 0
Rallybio Corp. Common 75120L100 20,408 2,308,670 SH   SOLE   2,308,670 0 0
Regeneron Pharmaceuticals, Inc. Common 75886F107 90,338 143,049 SH   SOLE   143,049 0 0
Repare Therapeutics Inc. Common 760273102 615 29,150 SH   SOLE   29,150 0 0
ResMed Inc. Common 761152107 19,432 74,599 SH   SOLE   74,599 0 0
Sabra Health Care REIT, Inc. Common 78573L106 6,914 510,660 SH   SOLE   510,660 0 0
Sanofi Sponsored ADR 80105N105 6,185 123,454 SH   SOLE   123,454 0 0
Sarepta Therapeutics, Inc. Common 803607100 28,447 315,897 SH   SOLE   315,897 0 0
Scholar Rock Holding Corp. Common 80706P103 2,703 108,833 SH   SOLE   108,833 0 0
Seagen Inc. Common 81181C104 61,767 399,527 SH   SOLE   399,527 0 0
Smith & Nephew plc Sponsored ADR 83175M205 6,291 181,710 SH   SOLE   181,710 0 0
Spectrum Pharmaceuticals, Inc. Common 84763A108 146 114,670 SH   SOLE   114,670 0 0
STERIS plc Shares G8473T100 4,057 16,669 SH   SOLE   16,669 0 0
Stryker Corp. Common 863667101 49,093 183,582 SH   SOLE   183,582 0 0
Sutro Biopharma, Inc. Common 869367102 4,878 327,850 SH   SOLE   327,850 0 0
Syneos Health, Inc. Class A 87166B102 41,389 403,087 SH   SOLE   403,087 0 0
Takeda Pharmaceutical Co. Ltd. Sponsored ADS 874060205 2,864 210,146 SH   SOLE   210,146 0 0
Teva Pharmaceutical Industries Ltd. Sponsored ADR 881624209 3,682 459,651 SH   SOLE   459,651 0 0
Theravance Biopharma, Inc. Common G8807B106 7,252 656,296 SH   SOLE   656,296 0 0
Thermo Fisher Scientific Inc. Common 883556102 101,638 152,326 SH   SOLE   152,326 0 0
Theseus Pharmaceuticals, Inc. Common 88369M101 1,268 100,000 SH   SOLE   100,000 0 0
Travere Therapeutics, Inc. Common 89422G107 6,607 212,869 SH   SOLE   212,869 0 0
TScan Therapeutics, Inc. Common 89854M101 900 200,000 SH   SOLE   200,000 0 0
Ultragenyx Pharmaceutical Inc. Common 90400D108 11,834 140,726 SH   SOLE   140,726 0 0
uniQure N.V. Shares N90064101 10,820 521,693 SH   SOLE   521,693 0 0
United Therapeutics Corp. Common 91307C102 21,983 101,737 SH   SOLE   101,737 0 0
Unitedhealth Group Inc. Common 91324P102 160,863 320,354 SH   SOLE   320,354 0 0
Universal Health Realty Income Trust Shares 91359E105 670 11,258 SH   SOLE   11,258 0 0
Universal Health Services, Inc. Class B 913903100 7,783 60,023 SH   SOLE   60,023 0 0
VectivBio Holding AG Shares H9060V101 3,714 756,502 SH   SOLE   756,502 0 0
Ventas, Inc. Common 92276F100 12,684 248,131 SH   SOLE   248,131 0 0
Verona Pharma plc Sponsored ADR 925050106 5,053 751,905 SH   SOLE   751,905 0 0
Vertex Pharmaceuticals Inc. Common 92532F100 59,961 273,046 SH   SOLE   273,046 0 0
VYNE Therapeutics Inc. Common 92941V209 138 135,395 SH   SOLE   135,395 0 0
Waters Corp. Common 941848103 10,605 28,461 SH   SOLE   28,461 0 0
Welltower Inc. Common 95040Q104 17,418 203,083 SH   SOLE   203,083 0 0
Zai Lab Ltd. ADR 98887Q104 2,721 43,300 SH   SOLE   43,300 0 0
Zimmer Biomet Holdings, Inc. Common 98956P102 18,045 142,044 SH   SOLE   142,044 0 0
Zoetis Inc. Class A 98978V103 29,893 122,497 SH   SOLE   122,497 0 0
Zogenix, Inc. Common 98978L204 1,446 88,977 SH   SOLE   88,977 0 0