The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
2SEVENTY BIO INC COMMON STOCK 901384107 59,641 3,495,943 SH   SOLE   3,495,943 0 0
5 01 ACQUISITION CORP COM CL A 33836P105 1,970 200,000 SH   SOLE   200,000 0 0
AC IMMUNE SA SHS H00263105 1,940 485,005 SH   SOLE   485,005 0 0
ACADIA PHARMACEUTICALS INC COM 004225108 145,114 5,991,479 SH   SOLE   5,991,479 0 0
ADVERUM BIOTECHNOLOGIES INC COM 00773U108 1,371 1,046,700 SH   SOLE   1,046,700 0 0
AKOUOS INC COM 00973J101 9,386 1,975,984 SH   SOLE   1,975,984 0 0
ALECTOR INC COM 014442107 81,773 5,738,448 SH   SOLE   5,738,448 0 0
ALIGOS THERAPEUTICS INC COM 01626L105 8,489 3,948,360 SH   SOLE   3,948,360 0 0
ANAPTYSBIO INC COM 032724106 186,070 7,521,024 SH   SOLE   7,521,024 0 0
APELLIS PHARMACEUTICALS INC COM 03753U106 263,370 5,183,431 SH   SOLE   5,183,431 0 0
APPLIED MOLECULAR TRANS INC COM 03824M109 990 131,693 SH   SOLE   131,693 0 0
ARCUTIS BIOTHERAPEUTICS INC COM 03969K108 17,247 895,503 SH   SOLE   895,503 0 0
ARCUS BIOSCIENCES INC COM 03969F109 103,047 3,265,101 SH   SOLE   3,265,101 0 0
ARGENX SE SPONSORED ADR 04016X101 39,414 125,000 SH   SOLE   125,000 0 0
ARVINAS INC COM 04335A105 101,214 1,503,929 SH   SOLE   1,503,929 0 0
ARYA SCIENCES ACQU CORP IV CL A G31659108 1,470 150,000 SH   SOLE   150,000 0 0
ATEA PHARMACEUTICALS INC COM 04683R106 45,779 6,340,639 SH   SOLE   6,340,639 0 0
ATRECA INC CL A COM 04965G109 1,137 358,780 SH   SOLE   358,780 0 0
AVIDITY BIOSCIENCES INC COM 05370A108 50,968 2,759,505 SH   SOLE   2,759,505 0 0
BCLS ACQUISITION CORP COM CL A G0904B105 1,974 200,000 SH   SOLE   200,000 0 0
BICYCLE THERAPEUTICS PLC SPONSORED ADS 088786108 24,022 547,453 SH   SOLE   547,453 0 0
BOLT BIOTHERAPEUTICS INC COM 097702104 411 150,000 SH   SOLE   150,000 0 0
C4 THERAPEUTICS INC COM STK 12529R107 4,852 200,000 SH   SOLE   200,000 0 0
CAREMAX INC *W EXP 06/08/202 14171W111 747 100,000 SH   SOLE   100,000 0 0
CARIBOU BIOSCIENCES INC COM 142038108 689 75,000 SH   SOLE   75,000 0 0
CENTESSA PHARMACEUTICALS PLC SPONSORED ADS 152309100 4,077 454,545 SH   SOLE   454,545 0 0
CEREVEL THERAPEUTICS HLDNG I COM 15678U128 57,636 1,646,260 SH   SOLE   1,646,260 0 0
CHINOOK THERAPEUTICS INC COM 16961L106 11,288 690,000 SH   SOLE   690,000 0 0
CRINETICS PHARMACEUTICALS IN COM 22663K107 17,345 790,209 SH   SOLE   790,209 0 0
DESIGN THERAPEUTICS INC COM 25056L103 38,299 2,371,445 SH   SOLE   2,371,445 0 0
DYNE THERAPEUTICS INC COM 26818M108 2,073 215,000 SH   SOLE   215,000 0 0
EDGEWISE THERAPEUTICS INC COM 28036F105 22,890 2,359,808 SH   SOLE   2,359,808 0 0
ERASCA INC COM 29479A108 5,835 678,441 SH   SOLE   678,441 0 0
EUCRATES BIOMEDICAL ACQU COR SHS G3141W106 1,968 200,000 SH   SOLE   200,000 0 0
EUCRATES BIOMEDICAL ACQU COR *W EXP 10/23/202 G3141W122 656 66,666 SH Call SOLE   66,666 0 0
EXELIXIS INC COM 30161Q104 21,567 951,333 SH   SOLE   951,333 0 0
FRAZIER LIFESCIENCES ACQU CO *W EXP 11/30/202 G3710A113 655 66,665 SH   SOLE   66,665 0 0
FRAZIER LIFESCIENCES ACQU CO CL A SHS G3710A105 5,776 587,615 SH   SOLE   587,615 0 0
PARDES BIOSCIENCES INC COM 69945Q105 1,394 200,000 SH   SOLE   200,000 0 0
GALAPAGOS NV SPON ADR 36315X101 198,193 3,195,624 SH   SOLE   3,195,624 0 0
GERON CORP COM 374163103 19,429 14,285,714 SH   SOLE   14,285,714 0 0
GRACELL BIOTECHNOLOGIES INC SPONSORED ADS 38406L103 3,634 1,559,710 SH   SOLE   1,559,710 0 0
GRAPHITE BIO INC COM 38870X104 5,224 1,024,279 SH   SOLE   1,024,279 0 0
HEALTH SCIENCES ACQ CORP 2 ORD SHS G4411D109 3,964 400,000 SH   SOLE   400,000 0 0
HELIX ACQUISITION CORP COM CL A G4444C102 2,220 200,000 SH   SOLE   200,000 0 0
HOOKIPA PHARMA INC COM 43906K100 11,400 5,000,000 SH   SOLE   5,000,000 0 0
IGM BIOSCIENCES INC COM 449585108 7,981 298,597 SH   SOLE   298,597 0 0
ITEOS THERAPEUTICS INC COM 46565G104 2,343 72,821 SH   SOLE   72,821 0 0
JANUX THERAPEUTICS INC COM 47103J105 20,382 1,421,319 SH   SOLE   1,421,319 0 0
JIYA ACQUISITION CORP COM CL A 47760M102 4,915 500,000 SH   SOLE   500,000 0 0
KINNATE BIOPHARMA INC COM 49705R105 1,971 175,000 SH   SOLE   175,000 0 0
KRONOS BIO INC COM 50107A104 2,363 326,780 SH   SOLE   326,780 0 0
KURA ONCOLOGY INC COM 50127T109 106,745 6,638,371 SH   SOLE   6,638,371 0 0
MERSANA THERAPEUTICS INC COM 59045L106 1,303 326,578 SH   SOLE   326,578 0 0
MIRATI THERAPEUTICS INC COM 60468T105 41,161 500,622 SH   SOLE   500,622 0 0
MORPHIC HLDG INC COM 61775R105 158,655 3,951,566 SH   SOLE   3,951,566 0 0
NGM BIOPHARMACEUTICALS INC COM 62921N105 8,252 541,108 SH   SOLE   541,108 0 0
NURIX THERAPEUTICS INC COM 67080M103 3,565 254,473 SH   SOLE   254,473 0 0
NUVATION BIO INC *W EXP 07/07/202 67080N119 5,067 963,333 SH   SOLE   963,333 0 0
NUVATION BIO INC COM CL A 67080N101 73,096 13,896,543 SH   SOLE   13,896,543 0 0
OMEGA ALPHA SPAC CL A G6749V107 491 50,000 SH   SOLE   50,000 0 0
ORIC PHARMACEUTICALS INC COM 68622P109 18,252 3,418,068 SH   SOLE   3,418,068 0 0
OVID THERAPEUTICS INC COM 690469101 19,209 6,117,400 SH   SOLE   6,117,400 0 0
PMV PHARMACEUTICALS INC COM 69353Y103 13,529 649,786 SH   SOLE   649,786 0 0
PROTAGONIST THERAPEUTICS INC COM 74366E102 9,039 381,711 SH   SOLE   381,711 0 0
PROTHENA CORP PLC SHS G72800108 423,637 11,584,280 SH   SOLE   11,584,280 0 0
RADIUS HEALTH INC COM NEW 750469207 309 35,000 SH   SOLE   35,000 0 0
REATA PHARMACEUTICALS INC CL A 75615P103 64,721 1,975,611 SH   SOLE   1,975,611 0 0
RELAY THERAPEUTICS INC COM 75943R102 68,583 2,291,441 SH   SOLE   2,291,441 0 0
REPARE THERAPEUTICS INC COM 760273102 712 50,000 SH   SOLE   50,000 0 0
REVOLUTION MEDICINES INC COM 76155X100 32,502 1,274,097 SH   SOLE   1,274,097 0 0
SAREPTA THERAPEUTICS INC COM 803607100 161,680 2,069,634 SH   SOLE   2,069,634 0 0
SILVERBACK THERAPEUTICS INC COM 82835W108 1,157 329,537 SH   SOLE   329,537 0 0
SOLID BIOSCIENCES INC COM 83422E105 3,078 2,565,102 SH   SOLE   2,565,102 0 0
SPRINGWORKS THERAPEUTICS INC COM 85205L107 18,393 325,881 SH   SOLE   325,881 0 0
SURFACE ONCOLOGY INC COM 86877M209 13,680 4,653,000 SH   SOLE   4,653,000 0 0
SURROZEN INC *W EXP 08/01/203 86889P117 201 66,665 SH   SOLE   66,665 0 0
TANGO THERAPEUTICS INC COM 87583X109 5,776 761,971 SH   SOLE   761,971 0 0
TURMERIC ACQUISITION CORP CL A G9127T108 985 100,000 SH   SOLE   100,000 0 0
TURMERIC ACQUISITION CORP *W EXP 10/08/202 G9127T124 328 33,333 SH   SOLE   33,333 0 0
VAXCYTE INC COM 92243G108 31,509 1,304,741 SH   SOLE   1,304,741 0 0
VENTYX BIOSCIENCES INC COM 92332V107 17,641 1,300,000 SH   SOLE   1,300,000 0 0
VERVE THERAPEUTICS INC COM 92539P101 2,250 98,593 SH   SOLE   98,593 0 0
VOYAGER THERAPEUTICS INC COM 92915B106 27,108 3,557,507 SH   SOLE   3,557,507 0 0
XENCOR INC COM 98401F105 132,566 4,968,756 SH   SOLE   4,968,756 0 0
ZAI LAB LTD ADR 98887Q104 97,777 2,223,212 SH   SOLE   2,223,212 0 0
ZENTALIS PHARMACEUTICALS INC COM 98943L107 5,317 115,236 SH   SOLE   115,236 0 0