The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ABCAM PLC ADS 000380204 26,208 1,432,900 SH   SOLE   1,432,900 0 0
ACADIA HEALTHCARE COMPANY IN COM 00404A109 49,377 753,500 SH   SOLE   753,500 0 0
ACCOLADE INC COM 00437E102 26,428 1,505,000 SH   SOLE   1,505,000 0 0
ACELRX PHARMACEUTICALS INC COM 00444T100 1,807 6,329,202 SH   SOLE   6,329,202 0 0
ACLARIS THERAPEUTICS INC COM 00461U105 66,633 3,865,034 SH   SOLE   3,865,034 0 0
ADAPTIMMUNE THERAPEUTICS PLC SPONDS ADR 00653A107 4,732 2,297,194 SH   SOLE   2,297,194 0 0
AEGLEA BIOTHERAPEUTICS INC COM 00773J103 4,166 1,811,425 SH   SOLE   1,811,425 0 0
AGILON HEALTH INC COM 00857U107 193,674 7,640,000 SH   SOLE   7,640,000 0 0
AGIOS PHARMACEUTICALS INC COM 00847X104 77,586 2,665,275 SH   SOLE   2,665,275 0 0
AKERO THERAPEUTICS INC COM 00973Y108 9,014 635,214 SH   SOLE   635,214 0 0
ALIGN TECHNOLOGY INC COM 016255101 94,394 216,500 SH   SOLE   216,500 0 0
ALNYLAM PHARMACEUTICALS INC COM 02043Q107 54,294 332,500 SH   SOLE   332,500 0 0
AMARIN CORP PLC SPONS ADR NEW 023111206 14,541 4,419,700 SH   SOLE   4,419,700 0 0
AMICUS THERAPEUTICS INC COM 03152W109 9,588 1,012,506 SH   SOLE   1,012,506 0 0
AMRYT PHARMA PLC SPONSORED ADS 03217L106 10,799 1,305,825 SH   SOLE   1,305,825 0 0
AMYLYX PHARMACEUTICALS INC COM 03237H101 12,828 998,307 SH   SOLE   998,307 0 0
ANAPTYSBIO INC COM 032724106 13,936 563,300 SH   SOLE   563,300 0 0
APPLIED THERAPEUTICS INC COM 03828A101 1,481 701,680 SH   SOLE   701,680 0 0
ARGENX SE SPONSORED ADR 04016X101 110,359 350,000 SH   SOLE   350,000 0 0
ARVINAS INC COM 04335A105 30,796 457,600 SH   SOLE   457,600 0 0
ASCENDIS PHARMA A/S SPONSORED ADR 04351P101 48,998 417,500 SH   SOLE   417,500 0 0
ATHIRA PHARMA INC COM 04746L104 7,455 552,252 SH   SOLE   552,252 0 0
ATRECA INC CL A COM 04965G109 1,466 462,530 SH   SOLE   462,530 0 0
AURA BIOSCIENCES INC COM 05153U107 22,179 1,008,114 SH   SOLE   1,008,114 0 0
AURINIA PHARMACEUTICALS INC COM 05156V102 9,545 771,018 SH   SOLE   771,018 0 0
BAXTER INTL INC COM 071813109 58,209 750,700 SH   SOLE   750,700 0 0
BCLS ACQUISITION CORP COM CL A G0904B105 3,050 309,000 SH   SOLE   309,000 0 0
BIOMARIN PHARMACEUTICAL INC COM 09061G101 20,393 264,500 SH   SOLE   264,500 0 0
BIOMEA FUSION INC COM 09077A106 5,198 1,165,582 SH   SOLE   1,165,582 0 0
BLUEPRINT MEDICINES CORP COM 09627Y109 60,540 947,715 SH   SOLE   947,715 0 0
CELLDEX THERAPEUTICS INC NEW COM NEW 15117B202 3,315 97,317 SH   SOLE   97,317 0 0
CEREVEL THERAPEUTICS HLDNG I COM 15678U128 60,334 1,723,341 SH   SOLE   1,723,341 0 0
CHINOOK THERAPEUTICS INC COM 16961L106 11,458 700,349 SH   SOLE   700,349 0 0
CINCOR PHARMA INC COM 17240Y109 18,087 1,031,159 SH   SOLE   1,031,159 0 0
COLLEGIUM PHARMACEUTICAL INC COM 19459J104 14,761 725,000 SH   SOLE   725,000 0 0
COMPASS THERAPEUTICS INC COM 20454B104 7,299 5,328,088 SH   SOLE   5,328,088 0 0
COMPUGEN LTD ORD M25722105 4,154 1,289,990 SH   SOLE   1,289,990 0 0
CONMED CORP COM 207410101 30,081 202,500 SH   SOLE   202,500 0 0
COVETRUS INC COM 22304C100 28,123 1,675,000 SH   SOLE   1,675,000 0 0
CULLINAN ONCOLOGY INC COM 230031106 6,832 652,578 SH   SOLE   652,578 0 0
CYTOKINETICS INC NOTE 4.000%11/1 23282WAA8 29,275 8,000,000 PRN   SOLE   8,000,000 0 0
DESIGN THERAPEUTICS INC COM 25056L103 5,581 345,597 SH   SOLE   345,597 0 0
DEXCOM INC COM 252131107 53,206 104,000 SH   SOLE   104,000 0 0
DYNAVAX TECHNOLOGIES CORP COM NEW 268158201 17,245 1,590,894 SH   SOLE   1,590,894 0 0
EDAP TMS S A SPONSORED ADR 268311107 5,945 820,000 SH   SOLE   820,000 0 0
EDWARDS LIFESCIENCES CORP COM 28176E108 70,220 596,500 SH   SOLE   596,500 0 0
ENCOMPASS HEALTH CORP COM 29261A100 35,733 502,500 SH   SOLE   502,500 0 0
EPIZYME INC COM 29428V104 8,358 7,267,696 SH   SOLE   7,267,696 0 0
EQRX INC COM 26886C107 4,130 1,000,000 SH   SOLE   1,000,000 0 0
ESSA PHARMA INC COM NEW 29668H708 3,244 524,944 SH   SOLE   524,944 0 0
EVOLENT HEALTH INC CL A 30050B101 76,874 2,380,000 SH   SOLE   2,380,000 0 0
EXACT SCIENCES CORP COM 30063P105 39,854 570,000 SH   SOLE   570,000 0 0
FATE THERAPEUTICS INC COM 31189P102 4,265 110,000 SH   SOLE   110,000 0 0
FRESHPET INC COM 358039105 60,814 592,500 SH   SOLE   592,500 0 0
F-STAR THERAPEUTICS INC COM 30315R107 2,669 751,889 SH   SOLE   751,889 0 0
FULCRUM THERAPEUTICS INC COM 359616109 10,278 434,590 SH   SOLE   434,590 0 0
FUSION PHARMACEUTICALS INC COM 36118A100 7,369 948,327 SH   SOLE   948,327 0 0
GAMIDA CELL LTD SHS M47364100 8,940 2,154,300 SH   SOLE   2,154,300 0 0
GOSSAMER BIO INC NOTE 5.000% 6/0 38341PAA0 7,692 9,573,000 PRN   SOLE   9,573,000 0 0
GRAPHITE BIO INC COM 38870X104 9,133 1,790,754 SH   SOLE   1,790,754 0 0
GUARDANT HEALTH INC COM 40131M109 13,248 200,000 SH   SOLE   200,000 0 0
HCA HEALTHCARE INC COM 40412C101 93,983 375,000 SH   SOLE   375,000 0 0
HEALTH CATALYST INC COM 42225T107 23,870 913,500 SH   SOLE   913,500 0 0
HORIZON THERAPEUTICS PUB L SHS G46188101 78,487 746,000 SH   SOLE   746,000 0 0
HUMANA INC COM 444859102 160,404 368,600 SH   SOLE   368,600 0 0
ICOSAVAX INC COM 45114M109 5,361 761,557 SH   SOLE   761,557 0 0
IDEXX LABS INC COM 45168D104 119,669 218,750 SH   SOLE   218,750 0 0
IMARA INC COM 45249V107 1,584 842,402 SH   SOLE   842,402 0 0
IMMUNOCORE HLDGS PLC ADS 45258D105 76,306 2,552,034 SH   SOLE   2,552,034 0 0
INOZYME PHARMA INC COM 45790W108 4,880 1,193,195 SH   SOLE   1,193,195 0 0
INSULET CORP COM 45784P101 128,320 481,700 SH   SOLE   481,700 0 0
INTERSECT ENT INC COM 46071F103 15,406 550,000 SH   SOLE   550,000 0 0
INTUITIVE SURGICAL INC COM NEW 46120E602 90,051 298,500 SH   SOLE   298,500 0 0
INVITAE CORP COM 46185L103 26,491 3,323,821 SH   SOLE   3,323,821 0 0
IRHYTHM TECHNOLOGIES INC COM 450056106 68,657 436,000 SH   SOLE   436,000 0 0
JIYA ACQUISITION CORP COM CL A 47760M102 2,027 206,200 SH   SOLE   206,200 0 0
KARUNA THERAPEUTICS INC COM 48576A100 54,842 432,543 SH   SOLE   432,543 0 0
KINNATE BIOPHARMA INC COM 49705R105 3,875 344,146 SH   SOLE   344,146 0 0
KYMERA THERAPEUTICS INC COM 501575104 31,989 755,875 SH   SOLE   755,875 0 0
LEAP THERAPEUTICS INC COM 52187K101 6,292 3,595,447 SH   SOLE   3,595,447 0 0
LEGEND BIOTECH CORP SPONSORED ADS 52490G102 14,942 411,184 SH   SOLE   411,184 0 0
LIFESTANCE HEALTH GROUP INC COM 53228F101 20,220 2,000,000 SH   SOLE   2,000,000 0 0
MACROGENICS INC COM 556099109 8,217 932,728 SH   SOLE   932,728 0 0
MADRIGAL PHARMACEUTICALS INC COM 558868105 26,836 273,500 SH   SOLE   273,500 0 0
MEREO BIOPHARMA GROUP PLC ADS 589492107 6,804 6,074,943 SH   SOLE   6,074,943 0 0
MERSANA THERAPEUTICS INC COM 59045L106 14,986 3,755,820 SH   SOLE   3,755,820 0 0
MIRATI THERAPEUTICS INC COM 60468T105 46,021 559,734 SH   SOLE   559,734 0 0
MIRUM PHARMACEUTICALS INC COM 604749101 36,690 1,666,208 SH   SOLE   1,666,208 0 0
NEUROCRINE BIOSCIENCES INC NOTE 2.250% 5/1 64125CAD1 1,320 1,000,000 PRN   SOLE   1,000,000 0 0
NEUROCRINE BIOSCIENCES INC COM 64125C109 103,594 1,105,000 SH   SOLE   1,105,000 0 0
NEVRO CORP COM 64157F103 52,186 721,500 SH   SOLE   721,500 0 0
NEVRO CORP NOTE 2.750% 4/0 64157FAC7 541 500,000 PRN   SOLE   500,000 0 0
NKARTA INC COM 65487U108 5,803 509,948 SH   SOLE   509,948 0 0
NOVAVAX INC COM NEW 670002401 33,010 448,200 SH   SOLE   448,200 0 0
NOVOCURE LTD ORD SHS G6674U108 14,499 175,000 SH   SOLE   175,000 0 0
NUVATION BIO INC *W EXP 07/07/202 67080N119 108 134,028 SH   SOLE   134,028 0 0
OLINK HLDG AB SPONSORED ADS 680710100 17,413 986,000 SH   SOLE   986,000 0 0
ORION ACQUISITION CORP UNIT 02/19/2026 68626A207 9,820 1,000,000 SH   SOLE   1,000,000 0 0
PACIRA BIOSCIENCES INC COM 695127100 76,320 1,000,000 SH   SOLE   1,000,000 0 0
PARATEK PHARMACEUTICALS INC COM 699374302 5,128 1,726,637 SH   SOLE   1,726,637 0 0
PENUMBRA INC COM 70975L107 45,426 204,500 SH   SOLE   204,500 0 0
PHASEBIO PHARMACEUTICALS INC COM 717224109 3,450 2,613,825 SH   SOLE   2,613,825 0 0
PHREESIA INC COM 71944F106 25,042 950,000 SH   SOLE   950,000 0 0
POSEIDA THERAPEUTICS INC COM 73730P108 1,298 289,754 SH   SOLE   289,754 0 0
PRELUDE THERAPEUTICS INC COM 74065P101 2,546 368,959 SH   SOLE   368,959 0 0
PROMETHEUS BIOSCIENCES INC COM 74349U108 23,574 624,307 SH   SOLE   624,307 0 0
PROTHENA CORP PLC SHS G72800108 24,265 663,530 SH   SOLE   663,530 0 0
PULMONX CORP COM 745848101 17,427 702,400 SH   SOLE   702,400 0 0
RADIUS HEALTH INC NOTE 3.000% 9/0 750469AA6 1,478 1,500,000 PRN   SOLE   1,500,000 0 0
RELAY THERAPEUTICS INC COM 75943R102 18,008 601,667 SH   SOLE   601,667 0 0
RENEO PHARMACEUTICALS INC COM 75974E103 3,361 1,143,185 SH   SOLE   1,143,185 0 0
RHYTHM PHARMACEUTICALS INC COM 76243J105 14,251 1,237,026 SH   SOLE   1,237,026 0 0
RIGEL PHARMACEUTICALS INC COM NEW 766559603 14,715 4,921,487 SH   SOLE   4,921,487 0 0
SAREPTA THERAPEUTICS INC COM 803607100 33,435 428,000 SH   SOLE   428,000 0 0
SEAGEN INC COM 81181C104 38,966 270,500 SH   SOLE   270,500 0 0
SHATTUCK LABS INC COM 82024L103 1,336 313,499 SH   SOLE   313,499 0 0
SHOCKWAVE MED INC COM 82489T104 56,298 271,500 SH   SOLE   271,500 0 0
SIERRA ONCOLOGY INC COM NEW 82640U404 37,652 1,174,786 SH   SOLE   1,174,786 0 0
SPERO THERAPEUTICS INC COM 84833T103 8,621 990,913 SH   SOLE   990,913 0 0
SPRUCE BIOSCIENCES INC COM 85209E109 3,262 1,622,689 SH   SOLE   1,622,689 0 0
TEMPEST THERAPEUTICS INC COM 87978U108 2,784 823,654 SH   SOLE   823,654 0 0
THERAVANCE BIOPHARMA INC NOTE 3.250%11/0 88339KAA0 1,420 1,500,000 PRN   SOLE   1,500,000 0 0
THESEUS PHARMACEUTICALS INC COM 88369M101 5,042 437,329 SH   SOLE   437,329 0 0
TRAVERE THERAPEUTICS INC COM 89422G107 24,524 951,650 SH   SOLE   951,650 0 0
TRAVERE THERAPEUTICS INC NOTE 2.500% 9/1 761299AB2 3,396 3,250,000 PRN   SOLE   3,250,000 0 0
ULTRAGENYX PHARMACEUTICAL IN COM 90400D108 74,661 1,028,109 SH   SOLE   1,028,109 0 0
UNITEDHEALTH GROUP INC COM 91324P102 122,393 240,000 SH   SOLE   240,000 0 0
VERVE THERAPEUTICS INC COM 92539P101 11,502 504,037 SH   SOLE   504,037 0 0
VIGIL NEUROSCIENCE INC COM 92673K108 3,318 471,958 SH   SOLE   471,958 0 0
VINCERX PHARMA INC COM NEW 92731L106 3,257 814,194 SH   SOLE   814,194 0 0
WARBY PARKER INC CL A COM 93403J106 35,112 1,038,500 SH   SOLE   1,038,500 0 0
WEST PHARMACEUTICAL SVSC INC COM 955306105 28,442 69,250 SH   SOLE   69,250 0 0
XENON PHARMACEUTICALS INC COM 98420N105 25,755 842,498 SH   SOLE   842,498 0 0
XILIO THERAPEUTICS INC COM 98422T100 8,421 1,191,094 SH   SOLE   1,191,094 0 0
ZAI LAB LTD ADR 98887Q104 53,035 1,205,900 SH   SOLE   1,205,900 0 0