The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ACUTUS MED INC COM 005111109 3,681 2,648,386 SH   DFND 1 2,648,386 0 0
ADAPTHEALTH CORP COMMON STOCK 00653Q102 186,751 11,650,072 SH   DFND 1 11,650,072 0 0
AERIE PHARMACEUTICALS INC NOTE 1.500%10/0 00771VAB4 141,877 157,390,000 PRN   DFND 1 157,390,000 0 0
AERIE PHARMACEUTICALS INC COM 00771V108 42,725 4,695,020 SH   DFND 1 4,695,020 0 0
ALECTOR INC COM 014442107 15,036 1,055,192 SH   DFND 1 1,055,192 0 0
ALPHATEC HLDGS INC COM NEW 02081G201 41,341 3,594,829 SH   DFND 1 3,594,829 0 0
AMERICAN WELL CORP CL A 03044L105 1,647 391,115 SH   DFND 1 391,115 0 0
AN2 THERAPEUTICS INC COM 037326105 8,803 584,136 SH   DFND 1 584,136 0 0
ANNEXON INC COM 03589W102 1,594 583,913 SH   DFND 1 583,913 0 0
APELLIS PHARMACEUTICALS INC NOTE 3.500% 9/1 03753UAB2 81,724 51,885,000 PRN   DFND 1 51,885,000 0 0
APOLLO ENDOSURGERY INC COM 03767D108 10,588 1,750,000 SH   DFND 1 1,750,000 0 0
BELLUS HEALTH INC NEW COM NEW 07987C204 25,269 3,672,808 SH   DFND 1 3,672,808 0 0
BENEFITFOCUS INC NOTE 1.250%12/1 08180DAB2 6,311 6,500,000 SH   DFND 1 6,500,000 0 0
BIOATLA INC COM 09077B104 1,445 289,002 SH   DFND 1 289,002 0 0
BIOCRYST PHARMACEUTICALS INC COM 09058V103 16,455 1,012,000 SH   DFND 1 1,012,000 0 0
BRIDGEBIO PHARMA INC NOTE 2.500% 3/1 10806XAB8 47,402 80,000,000 PRN   DFND 1 80,000,000 0 0
BROOKDALE SR LIVING INC COM 112463104 37,922 5,379,000 SH   DFND 1 5,379,000 0 0
BUTTERFLY NETWORK INC *W EXP 02/12/202 124155110 748 733,333 SH   DFND 1 733,333 0 0
CABALETTA BIO INC COM 12674W109 942 464,252 SH   DFND 1 464,252 0 0
CAREMAX INC COM CL A 14171W103 121,813 15,861,090 SH   DFND 1 15,861,090 0 0
CAREMAX INC *W EXP 06/08/202 14171W111 1,277 672,000 SH   DFND 1 672,000 0 0
CENTENE CORP DEL COM 15135B101 46,624 553,800 SH   DFND 1 553,800 0 0
COGENT BIOSCIENCES INC COM 19240Q201 11,991 1,601,000 SH   DFND 1 1,601,000 0 0
CULLINAN ONCOLOGY INC COM 230031106 3,932 375,585 SH   DFND 1 375,585 0 0
CYTOKINETICS INC COM NEW 23282W605 35,069 952,703 SH   DFND 1 952,703 0 0
DA32 LIFE SCNCE TEC ACQSTN C CLASS A COM 23312M106 15,544 1,600,000 SH   DFND 1 1,600,000 0 0
DAY ONE BIOPHARMACEUTICALS I COM 23954D109 20,698 2,086,449 SH   DFND 1 2,086,449 0 0
DECIPHERA PHARMACEUTICALS IN COM 24344T101 51,731 5,580,456 SH   DFND 1 5,580,456 0 0
DELCATH SYS INC COM NEW 24661P807 3,200 500,000 SH   DFND 1 500,000 0 0
EDGEWISE THERAPEUTICS INC COM 28036F105 38,151 3,933,137 SH   DFND 1 3,933,137 0 0
ENVISTA HOLDINGS CORPORATION NOTE 2.375% 6/0 29415FAB0 123,924 52,500,000 PRN   DFND 1 52,500,000 0 0
EUCRATES BIOMEDICAL ACQU COR *W EXP 10/23/202 G3141W122 62 333,333 SH   DFND 1 333,333 0 0
EUCRATES BIOMEDICAL ACQU COR UNIT 10/23/2027 G3141W114 0 1 SH   DFND 1 1 0 0
EUCRATES BIOMEDICAL ACQU COR SHS G3141W106 9,840 999,999 SH   DFND 1 999,999 0 0
EVOLUS INC COM 30052C107 13,792 1,229,234 SH   DFND 1 1,229,234 0 0
FOGHORN THERAPEUTICS INC COM 344174107 3,638 238,865 SH   DFND 1 238,865 0 0
GILEAD SCIENCES INC COM 375558103 45,508 765,489 SH   DFND 1 765,489 0 0
GLAUKOS CORP NOTE 2.750% 6/1 377322AB8 358,786 269,897,000 PRN   DFND 1 269,897,000 0 0
GLAUKOS CORP COM 377322102 21,365 369,514 SH   DFND 1 369,514 0 0
GLAUKOS CORP COM 377322102 2,613 45,200 SH Call DFND 1 45,200 0 0
GOODRX HLDGS INC COM CL A 38246G108 18,926 979,106 SH   DFND 1 979,106 0 0
GRAYBUG VISION INC COM SHS 38942Q103 6,497 5,281,713 SH   DFND 1 5,281,713 0 0
HEALTH CATALYST INC NOTE 2.500% 4/1 42225TAB3 17,171 15,000,000 PRN   DFND 1 15,000,000 0 0
HORIZON THERAPEUTICS PUB L SHS G46188101 48,923 465,000 SH   DFND 1 465,000 0 0
IGNYTE ACQUISITION CORP *W EXP 01/05/202 45175H114 132 362,500 SH   DFND 1 362,500 0 0
IGNYTE ACQUISITION CORP COM 45175H106 7,134 725,000 SH   DFND 1 725,000 0 0
IMMUNOGEN INC COM 45253H101 16,520 3,470,675 SH   DFND 1 3,470,675 0 0
INOZYME PHARMA INC COM 45790W108 9,590 2,344,786 SH   DFND 1 2,344,786 0 0
INSMED INC NOTE 1.750% 1/1 457669AA7 74,929 75,000,000 PRN   DFND 1 75,000,000 0 0
INSMED INC COM PAR $.01 457669307 7,157 304,572 SH   DFND 1 304,572 0 0
INSULET CORP NOTE 0.375% 9/0 45784PAK7 76,232 57,581,000 PRN   DFND 1 57,581,000 0 0
INTERCEPT PHARMACEUTICALS IN NOTE 3.250% 7/0 45845PAA6 52,992 57,791,000 PRN   DFND 1 57,791,000 0 0
INVITAE CORP NOTE 2.000% 9/0 46185LAB9 169,769 206,873,000 PRN   DFND 1 206,873,000 0 0
IVERIC BIO INC COM 46583P102 82,332 4,891,996 SH   DFND 1 4,891,996 0 0
KALVISTA PHARMACEUTICALS INC COM 483497103 12,241 830,472 SH   DFND 1 830,472 0 0
KINNATE BIOPHARMA INC COM 49705R105 11,097 985,568 SH   DFND 1 985,568 0 0
KURA ONCOLOGY INC COM 50127T109 71,015 4,416,361 SH   DFND 1 4,416,361 0 0
LARIMAR THERAPEUTICS INC COM 517125100 23,613 5,830,249 SH   DFND 1 5,830,249 0 0
MEDAVAIL HOLDINGS INC COM 58406B103 1,110 1,142,552 SH   DFND 1 1,142,552 0 0
MEDTECH ACQUISITION CORP UNIT 12/18/2025 58507N204 0 1 SH   DFND 1 1 0 0
MEDTECH ACQUISITION CORP COM CL A 58507N105 9,800 999,999 SH   DFND 1 999,999 0 0
MEDTECH ACQUISITION CORP *W EXP 12/22/202 58507N113 85 333,333 SH   DFND 1 333,333 0 0
MERUS N V COM N5749R100 11,554 437,000 SH   DFND 1 437,000 0 0
MIRATI THERAPEUTICS INC COM 60468T105 22,199 270,000 SH   DFND 1 270,000 0 0
MIRUM PHARMACEUTICALS INC COM 604749101 72,290 3,282,912 SH   DFND 1 3,282,912 0 0
MOLINA HEALTHCARE INC COM 60855R100 45,031 134,989 SH   DFND 1 134,989 0 0
NATERA INC NOTE 2.250% 5/0 632307AB0 120,177 90,638,000 PRN   DFND 1 90,638,000 0 0
NEOGENOMICS INC NOTE 0.250% 1/1 64049MAB6 1,666 2,500,000 PRN   DFND 1 2,500,000 0 0
NEUROCRINE BIOSCIENCES INC COM 64125C109 155,419 1,657,800 SH   DFND 1 1,657,800 0 0
NEVRO CORP NOTE 2.750% 4/0 64157FAC7 65,368 61,000,000 PRN   DFND 1 61,000,000 0 0
NOVAVAX INC NOTE 3.750% 2/0 670002AB0 26,777 25,000,000 PRN   DFND 1 25,000,000 0 0
NUVALENT INC COM 670703107 268,647 19,341,024 SH   DFND 1 19,341,024 0 0
NUVASIVE INC NOTE 0.375% 3/1 670704AJ4 76,133 80,000,000 PRN   DFND 1 80,000,000 0 0
NUVASIVE INC NOTE 1.000% 6/0 670704AL9 96,433 96,966,000 PRN   DFND 1 96,966,000 0 0
NUVATION BIO INC COM CL A 67080N101 18,816 3,577,233 SH   DFND 1 3,577,233 0 0
NUVATION BIO INC *W EXP 07/07/202 67080N119 135 166,666 SH   DFND 1 166,666 0 0
NYXOAH S A SHS B6S7WD106 8,714 455,262 SH   DFND 1 455,262 0 0
THE ONCOLOGY INSTITUTE INC *W EXP 11/15/202 68236X118 1,438 1,250,000 SH   DFND 1 1,250,000 0 0
THE ONCOLOGY INSTITUTE INC COM 68236X100 32,137 3,296,107 SH   DFND 1 3,296,107 0 0
ONCORUS INC COM 68236R103 5,605 3,148,977 SH   DFND 1 3,148,977 0 0
1LIFE HEALTHCARE INC NOTE 3.000% 6/1 68269GAB3 34,716 40,000,000 PRN   DFND 1 40,000,000 0 0
ORCHARD THERAPEUTICS PLC ADS 68570P101 4,948 6,949,416 SH   DFND 1 6,949,416 0 0
ORGANOGENESIS HLDGS INC COM 68621F102 64,441 8,456,876 SH   DFND 1 8,456,876 0 0
ORION ACQUISITION CORP *W EXP 02/19/202 68626A116 39 125,000 SH   DFND 1 125,000 0 0
ORION ACQUISITION CORP COM CL A 68626A108 4,885 500,000 SH   DFND 1 500,000 0 0
OAK STR HEALTH INC NOTE 3/1 67181AAB3 14,316 18,000,000 PRN   DFND 1 18,000,000 0 0
OUTSET MED INC COM 690145107 18,188 400,622 SH   DFND 1 400,622 0 0
PACIRA BIOSCIENCES INC NOTE 0.750% 8/0 695127AF7 100,908 81,600,000 PRN   DFND 1 81,600,000 0 0
PHARVARIS N V COM N69605108 28,600 1,577,078 SH   DFND 1 1,577,078 0 0
PMV PHARMACEUTICALS INC COM 69353Y103 10 470 SH   DFND 1 470 0 0
PROFOUND MED CORP COM NEW 74319B502 15,424 1,713,797 SH   DFND 1 1,713,797 0 0
PTC THERAPEUTICS INC NOTE 3.000% 8/1 69366JAB7 15,076 14,527,000 PRN   DFND 1 14,527,000 0 0
PULMONX CORP COM 745848101 91,681 3,695,341 SH   DFND 1 3,695,341 0 0
QUANTUM SI INC COM CL A 74765K105 6,552 1,400,000 SH   DFND 1 1,400,000 0 0
QUANTUM SI INC *W EXP 06/10/202 74765K113 383 333,333 SH   DFND 1 333,333 0 0
REVOLUTION HEALTHCAR AQ CORP CLASS A COM 76155Y108 9,810 1,000,000 SH   DFND 1 1,000,000 0 0
REVOLUTION HEALTHCAR AQ CORP *W EXP 12/31/202 76155Y116 90 200,000 SH   DFND 1 200,000 0 0
REVOLUTION MEDICINES INC COM 76155X100 22,744 891,587 SH   DFND 1 891,587 0 0
RHYTHM PHARMACEUTICALS INC COM 76243J105 3,352 291,005 SH   DFND 1 291,005 0 0
ROIVANT SCIENCES LTD *W EXP 09/30/202 G76279119 880 1,000,000 SH   DFND 1 1,000,000 0 0
SAREPTA THERAPEUTICS INC DBCV 1.500%11/1 803607AB6 116,124 88,657,000 SH   DFND 1 88,657,000 0 0
SARISSA CAPITAL ACQUISITN CO UNIT 10/23/2027 G7823W128 0 1 SH   DFND 1 1 0 0
SARISSA CAPITAL ACQUISITN CO CL A G7823W102 9,900 999,999 SH   DFND 1 999,999 0 0
SARISSA CAPITAL ACQUISITN CO *W EXP 10/23/202 G7823W110 120 333,333 SH   DFND 1 333,333 0 0
SEMA4 HOLDINGS CORP COM CL A 81663L101 42,515 13,848,488 SH   DFND 1 13,848,488 0 0
SENIOR CONNECT ACQUISITN COR *W EXP 12/31/202 81723H116 90 500,000 SH   DFND 1 500,000 0 0
SENIOR CONNECT ACQUISITN COR COM CL A 81723H108 9,820 1,000,000 SH   DFND 1 1,000,000 0 0
SILK RD MED INC COM 82710M100 88,927 2,153,712 SH   DFND 1 2,153,712 0 0
SINGULAR GENOMICS SYSTEMS IN COM 82933R100 41,722 6,612,019 SH   DFND 1 6,612,019 0 0
SOMALOGIC INC *W EXP 08/31/202 83444K113 257 120,000 SH   DFND 1 120,000 0 0
SPRINGWORKS THERAPEUTICS INC COM 85205L107 14,109 249,988 SH   DFND 1 249,988 0 0
SURROZEN INC *W EXP 08/01/203 86889P117 42 166,666 SH   DFND 1 166,666 0 0
TABULA RASA HEALTHCARE INC NOTE 1.750% 2/1 873379AA9 79,740 107,816,000 PRN   DFND 1 107,816,000 0 0
TERNS PHARMACEUTICALS INC COM 880881107 6,967 2,345,959 SH   DFND 1 2,345,959 0 0
TURMERIC ACQUISITION CORP *W EXP 10/08/202 G9127T124 82 250,000 SH   DFND 1 250,000 0 0
TURMERIC ACQUISITION CORP CL A G9127T108 7,388 750,000 SH   DFND 1 750,000 0 0
VIATRIS INC COM 92556V106 224,930 20,673,700 SH   DFND 1 20,673,700 0 0
VINCERX PHARMA INC COM NEW 92731L106 5,517 1,379,310 SH   DFND 1 1,379,310 0 0
WEREWOLF THERAPEUTICS INC COM 95075A107 4,216 958,125 SH   DFND 1 958,125 0 0
WINDTREE THERAPEUTICS INC COM 97382D303 23 20,148 SH   DFND 1 20,148 0 0
XERIS BIOPHARMA HOLDINGS INC NOTE 5.000% 7/1 98422LAA5 21,095 18,000,000 PRN   DFND 1 18,000,000 0 0
XILIO THERAPEUTICS INC COM 98422T100 14,696 2,078,692 SH   DFND 1 2,078,692 0 0