The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
Aerojet Rocketdyne Holdings In Common Stock 007800105 2,859 70,169 SH   SOLE   70,169 0 0
AeroVironment Inc Common Stock 008073108 92,317 1,003,885 SH   SOLE   1,003,885 0 0
Align Technology Inc Common Stock 016255101 2,905 10,462 SH   SOLE   10,462 0 0
Allegheny Technologies Inc Common Stock 01741R102 256 9,311 SH   SOLE   9,311 0 0
Alphabet Inc Common Stock 02079K107 32,998 14,468 SH   SOLE   14,468 0 0
Altair Engineering Inc Common Stock 021369103 8,128 147,898 SH   SOLE   147,898 0 0
Amazon.com Inc Common Stock 023135106 8,631 3,590 SH   SOLE   3,590 0 0
AMETEK Inc Common Stock 031100100 4,099 33,744 SH   SOLE   33,744 0 0
ANSYS Inc Common Stock 03662Q105 24,273 93,230 SH   SOLE   93,230 0 0
Arcturus Therapeutics Holdings Common Stock 03969T109 45,799 2,303,751 SH   SOLE   2,303,751 0 0
Autodesk Inc Common Stock 052769106 9,194 44,254 SH   SOLE   44,254 0 0
Baidu Inc ADR 056752108 14 100 SH   SOLE   100 0 0
Renishaw PLC Common Stock G75006117 7,247 141,309 SH   SOLE   141,309 0 0
CareDx Inc Common Stock 14167L103 100,486 3,995,450 SH   SOLE   3,995,450 0 0
Carpenter Technology Corp Common Stock 144285103 234 6,651 SH   SOLE   6,651 0 0
Castle Biosciences Inc Common Stock 14843C105 0 0 SH   SOLE   0 0 0
Cerus Corp Common Stock 157085101 84,700 17,111,062 SH   SOLE   15,742,875 476,564 891,623
Codexis Inc Common Stock 192005106 47,917 4,486,573 SH   SOLE   4,486,573 0 0
Deere & Co Common Stock 244199105 67,699 189,219 SH   SOLE   189,219 0 0
DuPont de Nemours Inc Common Stock 26614N102 280 4,120 SH   SOLE   4,120 0 0
Eastman Chemical Co Common Stock 277432100 294 2,666 SH   SOLE   2,666 0 0
Editas Medicine Inc Common Stock 28106W103 2,885 253,326 SH   SOLE   58,126 189,951 5,249
FARO Technologies Inc Common Stock 311642102 5,972 185,352 SH   SOLE   185,352 0 0
Fate Therapeutics Inc Common Stock 31189P102 265,041 11,473,655 SH   SOLE   11,257,902 0 215,753
Grayscale Bitcoin Trust BTC Open-End Fund 389637109 139,387 6,786,143 SH   SOLE   6,145,125 632,473 8,545
HP Inc Common Stock 40434L105 8,113 208,891 SH   SOLE   208,891 0 0
Hexcel Corp Common Stock 428291108 289 5,026 SH   SOLE   5,026 0 0
Incyte Corp Common Stock 45337C102 92,525 1,219,195 SH   SOLE   1,219,195 0 0
Intellia Therapeutics Inc Common Stock 45826J105 439,003 9,514,580 SH   SOLE   8,483,692 697,789 333,099
Intercontinental Exchange Inc Common Stock 45866F104 12,030 117,492 SH   SOLE   117,492 0 0
Intuit Inc Common Stock 461202103 12,327 29,743 SH   SOLE   29,743 0 0
Intuitive Surgical Inc Common Stock 46120E602 10,211 44,858 SH   SOLE   44,858 0 0
OC Oerlikon Corp AG Common Stock H59187106 3,187 420,753 SH   SOLE   420,753 0 0
Invitae Corp Common Stock 46185L103 105,215 28,668,950 SH   SOLE   24,697,303 2,918,837 1,052,810
Ionis Pharmaceuticals Inc Common Stock 462222100 171,691 4,701,297 SH   SOLE   4,701,297 0 0
Iovance Biotherapeutics Inc Common Stock 462260100 19,816 2,935,679 SH   SOLE   2,935,679 0 0
Iridium Communications Inc Common Stock 46269C102 81,521 2,196,746 SH   SOLE   2,196,746 0 0
JD.com Inc ADR 47215P106 19,848 353,677 SH   SOLE   353,677 0 0
SGL Carbon SE Common Stock D6949M108 329 52,968 SH   SOLE   52,968 0 0
Kaiser Aluminum Corp Common Stock 483007704 3,080 30,144 SH   SOLE   30,144 0 0
Komatsu Ltd ADR 500458401 66,961 2,713,178 SH   SOLE   2,713,178 0 0
Kratos Defense & Security Solu Common Stock 50077B207 118,664 8,229,121 SH   SOLE   8,229,121 0 0
Henkel AG & Co KGaA Preference D3207M110 304 4,449 SH   SOLE   4,449 0 0
LendingClub Corp Common Stock 52603A208 55 3,516 SH   SOLE   3,516 0 0
Lincoln Electric Holdings Inc Common Stock 533900106 3,178 23,400 SH   SOLE   23,400 0 0
Siemens AG Common Stock D69671218 3,202 24,235 SH   SOLE   24,235 0 0
Materialise NV ADR 57667T100 90,723 6,201,169 SH   SOLE   5,854,678 151,270 195,221
MercadoLibre Inc Common Stock 58733R102 75,782 96,430 SH   SOLE   96,430 0 0
Microsoft Corp Common Stock 594918104 8,306 30,550 SH   SOLE   30,550 0 0
Bezeq The Israeli Telecommunic Common Stock M2012Q100 2,075 1,343,324 SH   SOLE   1,343,324 0 0
Moog Inc Common Stock 615394202 2,825 34,711 SH   SOLE   34,711 0 0
Danel Adir Yeoshua Ltd Common Stock M27013107 1,756 13,252 SH   SOLE   13,252 0 0
Hilan Ltd Common Stock M5299H123 2,165 37,147 SH   SOLE   37,147 0 0
Nano Dimension Ltd ADR 63008G203 48,642 16,322,702 SH   SOLE   16,322,702 0 0
Elbit Systems Ltd Common Stock M3760D101 38,392 187,487 SH   SOLE   187,487 0 0
Partner Communications Co Ltd Common Stock M78465107 1,989 272,983 SH   SOLE   272,983 0 0
Netflix Inc Common Stock 64110L106 91 461 SH   SOLE   461 0 0
Nice Ltd ADR 653656108 2,100 10,567 SH   SOLE   10,567 0 0
Matrix IT Ltd Common Stock M6859E153 2,047 86,723 SH   SOLE   86,723 0 0
Toray Industries Inc Common Stock J89494116 300 57,803 SH   SOLE   57,803 0 0
PTC Inc Common Stock 69370C100 10,092 86,604 SH   SOLE   86,604 0 0
Pacific Biosciences of Califor Common Stock 69404D108 157,896 28,045,530 SH   SOLE   26,282,405 1,329,743 433,382
One Software Technologies Ltd Common Stock M75260113 1,992 129,411 SH   SOLE   129,411 0 0
Personalis Inc Common Stock 71535D106 21,177 5,347,820 SH   SOLE   5,347,820 0 0
Proto Labs Inc Common Stock 743713109 30,328 629,339 SH   SOLE   629,339 0 0
Roku Inc Common Stock 77543R102 962,719 10,144,564 SH   SOLE   9,239,633 673,464 231,467
Shopify Inc Common Stock 82509L107 455,203 1,213,486 SH   SOLE   1,131,988 62,663 18,835
Splunk Inc Common Stock 848637104 122 1,189 SH   SOLE   1,189 0 0
Block Inc Common Stock 852234103 799,455 9,135,579 SH   SOLE   8,455,297 0 0
Teladoc Health Inc Common Stock 87918A105 691,821 20,293,962 SH   SOLE   18,762,144 1,107,267 424,551
Teradyne Inc Common Stock 880770102 48,608 444,886 SH   SOLE   444,886 0 0
Tesla Inc Common Stock 88160R101 1,094,679 1,443,673 SH   SOLE   1,349,506 92,409 1,758
Teva Pharmaceutical Industries ADR 881624209 2,116 232,518 SH   SOLE   232,518 0 0
3D Systems Corp Common Stock 88554D205 39,711 3,673,560 SH   SOLE   3,673,560 0 0
3M Co Common Stock 88579Y101 282 1,891 SH   SOLE   1,891 0 0
Trimble Inc Common Stock 896239100 139,643 2,052,072 SH   SOLE   2,052,072 0 0
Twilio Inc Common Stock 90138F102 586,053 5,572,436 SH   SOLE   5,146,381 310,474 115,581
Twist Bioscience Corp Common Stock 90184D100 213,353 6,267,721 SH   SOLE   6,059,143 121,899 86,679
2U Inc Common Stock 90214J101 89,342 9,586,065 SH   SOLE   8,332,232 827,308 426,525
United Parcel Service Inc Common Stock 911312106 2,937 16,114 SH   SOLE   16,114 0 0
Veracyte Inc Common Stock 92337F107 155,693 8,856,245 SH   SOLE   8,251,067 596,881 8,297
Workday Inc Common Stock 98138H101 113 722 SH   SOLE   722 0 0
Xerox Holdings Corp Common Stock 98421M106 273 14,509 SH   SOLE   14,509 0 0
Zillow Group Inc Common Stock 98954M200 33,203 832,147 SH   SOLE   832,147 0 0
Koninklijke DSM NV Common Stock N5017D122 282 1,673 SH   SOLE   1,673 0 0
Arkema SA Common Stock F0392W125 295 2,441 SH   SOLE   2,441 0 0
Sandvik AB Common Stock W74857165 290 14,171 SH   SOLE   14,171 0 0
Cellcom Israel Ltd Common Stock M2196U109 1,871 380,491 SH   SOLE   380,491 0 0
Evonik Industries AG Common Stock D2R90Y117 287 10,742 SH   SOLE   10,742 0 0
Fattal Holdings 1998 Ltd Common Stock M4148G105 1,901 15,551 SH   SOLE   15,551 0 0
SLM Solutions Group AG Common Stock D6T690109 5,951 528,102 SH   SOLE   528,102 0 0
Adyen NV Common Stock N3501V104 46,012 29,625 SH   SOLE   29,625 0 0
Sapiens International Corp NV Common Stock G7T16G103 2,254 88,992 SH   SOLE   88,992 0 0
CRISPR Therapeutics AG Common Stock H17182108 564,683 9,727,531 SH   SOLE   8,851,672 639,011 236,848
Spotify Technology SA Common Stock L8681T102 230,430 2,043,367 SH   SOLE   1,904,410 98,033 40,924
Allot Ltd Common Stock M0854Q105 1,872 357,287 SH   SOLE   357,287 0 0
AudioCodes Ltd Common Stock M15342104 2,073 90,288 SH   SOLE   90,288 0 0
Camtek Ltd/Israel Common Stock M20791105 2,100 71,116 SH   SOLE   71,116 0 0
Ceragon Networks Ltd Common Stock M22013102 1,858 1,049,583 SH   SOLE   1,049,583 0 0
Check Point Software Technolog Common Stock M22465104 1,964 15,700 SH   SOLE   15,700 0 0
Compugen Ltd Common Stock M25722105 19,946 10,781,621 SH   SOLE   10,456,932 192,471 132,218
CyberArk Software Ltd Common Stock M2682V108 1,929 13,886 SH   SOLE   13,886 0 0
Fiverr International Ltd Common Stock M4R82T106 1,716 40,565 SH   SOLE   40,565 0 0
Ituran Location and Control Lt Common Stock M6158M104 2,440 97,352 SH   SOLE   97,352 0 0
Nova Ltd Common Stock M7516K103 2,311 21,761 SH   SOLE   21,761 0 0
Radware Ltd Common Stock M81873107 1,733 71,824 SH   SOLE   71,824 0 0
Stratasys Ltd Common Stock M85548101 162,980 8,173,499 SH   SOLE   7,059,924 537,421 576,154
Taro Pharmaceutical Industries Common Stock M8737E108 2,049 55,940 SH   SOLE   55,940 0 0
Tower Semiconductor Ltd Common Stock M87915274 2,234 46,297 SH   SOLE   46,297 0 0
UroGen Pharma Ltd Common Stock M96088105 1,607 302,124 SH   SOLE   302,124 0 0
Wix.com Ltd Common Stock M98068105 1,641 26,038 SH   SOLE   26,038 0 0
DocuSign Inc Common Stock 256163106 134 1,597 SH   SOLE   1,597 0 0
Discovery Ltd Common Stock S2192Y109 51,843 5,556,092 SH   SOLE   5,556,092 0 0
Inmode Ltd Common Stock M5425M103 1,974 73,637 SH   SOLE   73,637 0 0
Perion Network Ltd Common Stock M78673114 1,854 94,381 SH   SOLE   94,381 0 0
Silvergate Capital Corp Common Stock 82837P408 34,792 443,211 SH   SOLE   443,211 0 0
Z Holdings Corp Common Stock J9894K105 13,177 3,974,498 SH   SOLE   3,974,498 0 0
Sea Ltd ADR 81141R100 71,795 868,561 SH   SOLE   835,838 31,780 943
Z Holdings Corp ADR 98877X101 72 10,836 SH   SOLE   10,836 0 0
Synopsys Inc Common Stock 871607107 20,782 65,108 SH   SOLE   65,108 0 0
RADA Electronic Industries Ltd Common Stock M81863124 1,704 141,567 SH   SOLE   141,567 0 0
PagerDuty Inc Common Stock 69553P100 268,265 10,882,979 SH   SOLE   9,733,154 808,953 340,872
Caterpillar Inc Common Stock 149123101 22,260 103,129 SH   SOLE   103,129 0 0
Arconic Corp Common Stock 03966V107 3,165 112,529 SH   SOLE   112,529 0 0
Adaptive Biotechnologies Corp Common Stock 00650F109 68,605 8,773,018 SH   SOLE   8,773,018 0 0
10X Genomics Inc Common Stock 88025U109 184,452 3,603,286 SH   SOLE   3,262,437 255,785 85,064
Bitcoin Fund/The Closed-End Fund 09175G104 4,341 128,634 SH   SOLE   0 0 128,634
Schrodinger Inc/United States Common Stock 80810D103 76,310 2,953,172 SH   SOLE   2,953,172 0 0
TCS Group Holding PLC GDR 87238U203 0 608,351 SH   SOLE   608,351 0 0
Adyen NV ADR 00783V104 18,177 1,174,210 SH   SOLE   1,174,210 0 0
Cie Generale des Etablissement Common Stock F61824144 3,090 23,743 SH   SOLE   23,743 0 0
voestalpine AG Common Stock A9101Y103 309 10,540 SH   SOLE   10,540 0 0
Yeahka Ltd Common Stock G9835C108 53 21,200 SH   SOLE   21,200 0 0
Accolade Inc Common Stock 00437E102 40,127 6,250,275 SH   SOLE   6,250,275 0 0
Berkeley Lights Inc Common Stock 084310101 40,259 8,422,424 SH   SOLE   8,422,424 0 0
Vertex Pharmaceuticals Inc Common Stock 92532F100 98,197 365,522 SH   SOLE   365,522 0 0
BYD Co Ltd ADR 05606L100 31,658 445,831 SH   SOLE   445,831 0 0
Kamada Ltd Common Stock M6240T109 1,796 399,126 SH   SOLE   399,126 0 0
Gamida Cell Ltd Common Stock M47364100 1,558 714,534 SH   SOLE   714,534 0 0
Gilat Satellite Networks Ltd Common Stock M51474118 1,919 296,160 SH   SOLE   296,160 0 0
Silicom Ltd Common Stock M84116108 2,121 57,702 SH   SOLE   57,702 0 0
Organovo Holdings Inc Common Stock 68620A203 703 291,633 SH   SOLE   288,492 3,141 0
Surface Oncology Inc Common Stock 86877M209 10,281 5,557,382 SH   SOLE   5,557,382 0 0
Niu Technologies ADR 65481N100 19,320 2,467,428 SH   SOLE   2,467,428 0 0
Thermo Fisher Scientific Inc Common Stock 883556102 165 290 SH   SOLE   290 0 0
Exact Sciences Corp Common Stock 30063P105 745,744 14,971,765 SH   SOLE   13,828,560 845,093 298,112
Snowflake Inc Common Stock 833445109 108 843 SH   SOLE   843 0 0
Unity Software Inc Common Stock 91332U101 366,753 9,175,711 SH   SOLE   8,374,033 581,091 220,587
Beam Therapeutics Inc Common Stock 07373V105 309,305 8,792,064 SH   SOLE   8,792,064 0 0
Regeneron Pharmaceuticals Inc Common Stock 75886F107 37,100 55,811 SH   SOLE   55,811 0 0
Repare Therapeutics Inc Common Stock 760273102 25,514 2,779,331 SH   SOLE   2,779,331 0 0
Cloudflare Inc Common Stock 18915M107 18,180 324,635 SH   SOLE   324,635 0 0
Palantir Technologies Inc Common Stock 69608A108 4,701 541,577 SH   SOLE   84,404 448,730 8,443
Zoom Video Communications Inc Common Stock 98980L101 1,028,943 9,576,018 SH   SOLE   8,767,358 581,066 227,594
Honeywell International Inc Common Stock 438516106 4,850 25,048 SH   SOLE   25,048 0 0
Kaspi.KZ JSC GDR 48581R205 11,023 209,161 SH   SOLE   209,161 0 0
908 Devices Inc Common Stock 65443P102 50,505 3,628,220 SH   SOLE   3,628,220 0 0
Magna International Inc Common Stock 559222401 24,617 379,192 SH   SOLE   379,192 0 0
Peloton Interactive Inc Common Stock 70614W100 121 8,665 SH   SOLE   8,665 0 0
Veeva Systems Inc Common Stock 922475108 41,206 242,017 SH   SOLE   242,017 0 0
Grayscale Ethereum Trust Open-End Fund 389638107 7,949 631,401 SH   SOLE   5,430 625,971 0
1Life Healthcare Inc Common Stock 68269G107 49,133 5,800,797 SH   SOLE   5,800,797 0 0
PyroGenesis Canada Inc Common Stock 74734T104 385 145,098 SH   SOLE   145,098 0 0
Augwind Energy Tech Storage Lt Common Stock M6058P108 1,216 302,584 SH   SOLE   302,584 0 0
Electra Consumer Products 1970 Common Stock M3798N105 1,615 35,874 SH   SOLE   35,874 0 0
Magic Software Enterprises Ltd Common Stock 559166103 2,234 131,121 SH   SOLE   131,121 0 0
Malam - Team Ltd Common Stock M87437105 1,712 75,015 SH   SOLE   75,015 0 0
Plasson Industries Ltd Common Stock M7933B108 2,139 38,675 SH   SOLE   38,675 0 0
Desktop Metal Inc Common Stock 25058X105 3,950 1,926,947 SH   SOLE   1,926,947 0 0
Enlivex Therapeutics Ltd Common Stock M4130Y106 1,658 331,001 SH   SOLE   331,001 0 0
JFrog Ltd Common Stock M6191J100 1,716 92,022 SH   SOLE   92,022 0 0
Eastman Kodak Co Common Stock 277461406 210 45,547 SH   SOLE   45,547 0 0
Kornit Digital Ltd Common Stock M6372Q113 1,307 31,135 SH   SOLE   31,135 0 0
Lockheed Martin Corp Common Stock 539830109 16,262 36,950 SH   SOLE   36,950 0 0
Nano-X Imaging Ltd Common Stock M70700105 2,182 213,548 SH   SOLE   213,548 0 0
SolarEdge Technologies Inc Common Stock 83417M104 2,328 8,533 SH   SOLE   8,533 0 0
Teledyne Technologies Inc Common Stock 879360105 18,719 46,203 SH   SOLE   46,203 0 0
Twitter Inc Common Stock 90184L102 71 1,804 SH   SOLE   1,804 0 0
Butterfly Network Inc Common Stock 124155102 21,637 7,094,144 SH   SOLE   7,094,144 0 0
Signify Health Inc Common Stock 82671G100 298,257 21,882,411 SH   SOLE   20,997,938 491,995 392,478
ARK Innovation ETF ETP 00214Q104 2,573 58,357 SH   SOLE   58,357 0 0
Bill.com Holdings Inc Common Stock 090043100 18,451 156,047 SH   SOLE   156,047 0 0
DraftKings Holdings Inc Common Stock 26142R104 0 0 SH   SOLE   0 0 0
Vuzix Corp Common Stock 92921W300 47,834 7,359,067 SH   SOLE   7,359,067 0 0
Airbus SE Common Stock N0280G100 4,128 35,356 SH   SOLE   35,356 0 0
Thales SA Common Stock F9156M108 6,064 49,740 SH   SOLE   49,740 0 0
Komatsu Ltd Common Stock J35759125 20,742 834,288 SH   SOLE   834,288 0 0
Garmin Ltd Common Stock H2906T109 8,845 83,739 SH   SOLE   83,739 0 0
HEICO Corp Common Stock 422806109 3,986 27,862 SH   SOLE   27,862 0 0
L3Harris Technologies Inc Common Stock 502431109 19,466 80,806 SH   SOLE   80,806 0 0
The 3D Printing ETF ETP 00214Q500 22,328 944,888 SH   SOLE   944,888 0 0
ROBLOX Corp Common Stock 771049103 221,709 7,405,104 SH   SOLE   6,787,363 464,832 152,909
Spirit AeroSystems Holdings In Common Stock 848574109 5,752 183,064 SH   SOLE   183,064 0 0
UiPath Inc Common Stock 90364P105 641,751 37,595,245 SH   SOLE   35,197,208 1,792,460 605,577
Coinbase Global Inc Common Stock 19260Q107 699,091 8,951,225 SH   SOLE   8,224,432 561,431 165,362
TuSimple Holdings Inc Common Stock 90089L108 111,363 13,564,321 SH   SOLE   12,254,914 1,014,432 294,975
Recursion Pharmaceuticals Inc Common Stock 75629V104 16,720 2,732,087 SH   SOLE   2,732,087 0 0
Zymergen Inc Common Stock 98985X100 4,908 3,456,518 SH   SOLE   3,456,518 0 0
Okta Inc Common Stock 679295105 6,919 83,316 SH   SOLE   83,316 0 0
Blade Air Mobility Inc Common Stock 092667104 54,117 7,854,472 SH   SOLE   7,854,472 0 0
JD Logistics Inc Common Stock G5074S101 8,547 4,360,526 SH   SOLE   4,360,526 0 0
Hexagon AB Common Stock W4R431112 3,765 309,335 SH   SOLE   309,335 0 0
StoneCo Ltd Common Stock G85158106 26,457 2,635,151 SH   SOLE   2,635,151 0 0
Dynamics Special Purpose Corp Common Stock 268010105 21,891 2,202,281 SH   SOLE   2,202,281 0 0
Walt Disney Co/The Common Stock 254687106 8,742 79,157 SH   SOLE   79,157 0 0
Quantum-Si Inc Common Stock 74765K105 58,944 13,869,084 SH   SOLE   13,869,084 0 0
Verve Therapeutics Inc Common Stock 92539P101 30,837 2,034,124 SH   SOLE   2,034,124 0 0
Etsy Inc Common Stock 29786A106 4,830 59,545 SH   SOLE   59,545 0 0
Markforged Holding Corp Common Stock 57064N102 36,500 13,825,711 SH   SOLE   13,825,711 0 0
Dassault Systemes SE Common Stock F24571451 18,496 439,813 SH   SOLE   439,813 0 0
Conformis Inc Common Stock 20717E101 5,549 12,977,154 SH   SOLE   12,977,154 0 0
Exco Technologies Ltd Common Stock 30150P109 2,819 421,019 SH   SOLE   421,019 0 0
Xometry Inc Common Stock 98423F109 6,392 187,952 SH   SOLE   187,952 0 0
5N Plus Inc Common Stock 33833X101 194 154,820 SH   SOLE   154,820 0 0
BICO Group AB Common Stock W2R45B104 5,406 408,279 SH   SOLE   408,279 0 0
Farfetch Ltd Common Stock 30744W107 6,503 725,020 SH   SOLE   725,020 0 0
Robinhood Markets Inc Common Stock 770700102 337,581 33,556,789 SH   SOLE   30,793,767 2,150,135 612,887
Priortech Ltd Common Stock M8164J109 2,051 79,171 SH   SOLE   79,171 0 0
Playtika Holding Corp Common Stock 72815L107 1,825 123,201 SH   SOLE   123,201 0 0
Nayax Ltd Common Stock M7S750100 2,087 1,196,892 SH   SOLE   1,196,892 0 0
Cognyte Software Ltd Common Stock M25133105 1,922 271,405 SH   SOLE   271,405 0 0
Collplant Biotechnologies Ltd Common Stock M2R51X116 2,192 235,660 SH   SOLE   235,660 0 0
Innoviz Technologies Ltd Common Stock M5R635108 3,307 677,682 SH   SOLE   677,682 0 0
Monday.com Ltd Common Stock M7S64H106 26,866 236,624 SH   SOLE   236,624 0 0
SimilarWeb Ltd Common Stock M84137104 1,467 164,316 SH   SOLE   164,316 0 0
Tufin Software Technologies Lt Common Stock M8893U102 2,209 174,349 SH   SOLE   174,349 0 0
WalkMe Ltd Common Stock M97628107 1,414 143,817 SH   SOLE   143,817 0 0
Joby Aviation Inc Common Stock G65163100 8,003 1,356,398 SH   SOLE   1,356,398 0 0
General Electric Co Common Stock 369604301 2,611 33,353 SH   SOLE   33,353 0 0
Pfizer Inc Common Stock 717081103 38,940 734,165 SH   SOLE   734,165 0 0
Genius Sports Ltd Common Stock G3934V109 16,220 5,300,746 SH   SOLE   5,300,746 0 0
ARK Genomic Revolution ETF ETP 00214Q302 345 10,707 SH   SOLE   10,707 0 0
Ginkgo Bioworks Holdings Inc Common Stock 37611X100 269,063 87,358,057 SH   SOLE   81,027,707 4,741,511 1,588,839
SomaLogic Inc Common Stock 83444K105 61,998 10,333,075 SH Call SOLE   10,333,075 0 0
SomaLogic Inc Equity WRT 83444K113 274 300,000 SH   SOLE   300,000 0 0
Archer Aviation Inc Common Stock 03945R102 42,525 10,173,526 SH   SOLE   10,173,526 0 0
Toast Inc Common Stock 888787108 23,514 1,447,890 SH   SOLE   1,447,890 0 0
Velo3D Inc Common Stock 92259N104 26,397 10,730,382 SH   SOLE   10,730,382 0 0
Mynaric AG ADR 62857X101 4,890 580,776 SH   SOLE   580,776 0 0
Burning Rock Biotech Ltd ADR 12233L107 4,255 1,772,722 SH   SOLE   1,772,722 0 0
Nextdoor Holdings Inc Common Stock 65345M108 18,809 6,622,750 SH   SOLE   6,622,750 0 0
Abcam PLC ADR 000380204 140 9,425 SH   SOLE   9,425 0 0
Acushnet Holdings Corp Common Stock 005098108 173 4,256 SH   SOLE   4,256 0 0
Adobe Inc Common Stock 00724F101 157 377 SH   SOLE   377 0 0
Apple Inc Common Stock 037833100 146 983 SH   SOLE   983 0 0
Autoliv Inc Common Stock 052800109 181 2,260 SH   SOLE   2,260 0 0
Axon Enterprise Inc Common Stock 05464C101 126 1,247 SH   SOLE   1,247 0 0
Beyond Meat Inc Common Stock 08862E109 94 3,565 SH   SOLE   3,565 0 0
Bio-Techne Corp Common Stock 09073M104 146 396 SH   SOLE   396 0 0
Brady Corp Common Stock 104674106 180 3,716 SH   SOLE   3,716 0 0
Bruker Corp Common Stock 116794108 165 2,643 SH   SOLE   2,643 0 0
Buckle Inc/The Common Stock 118440106 171 5,207 SH   SOLE   5,207 0 0
Cboe Global Markets Inc Common Stock 12503M108 166 1,480 SH   SOLE   1,480 0 0
CDW Corp/DE Common Stock 12514G108 163 962 SH   SOLE   962 0 0
CRH PLC ADR 12626K203 178 4,295 SH   SOLE   4,295 0 0
Canada Goose Holdings Inc Common Stock 135086106 130 6,458 SH   SOLE   6,458 0 0
Canadian Solar Inc Common Stock 136635109 157 4,882 SH   SOLE   4,882 0 0
Cardlytics Inc Common Stock 14161W105 80 3,086 SH   SOLE   3,086 0 0
ChargePoint Holdings Inc Common Stock 15961R105 111 8,661 SH   SOLE   8,661 0 0
Corsair Gaming Inc Common Stock 22041X102 130 8,098 SH   SOLE   8,098 0 0
Crowdstrike Holdings Inc Common Stock 22788C105 19,519 122,000 SH   SOLE   122,000 0 0
Datadog Inc Common Stock 23804L103 108 1,134 SH   SOLE   1,134 0 0
Dropbox Inc Common Stock 26210C104 154 7,379 SH   SOLE   7,379 0 0
Dynatrace Inc Common Stock 268150109 137 3,637 SH   SOLE   3,637 0 0
Five9 Inc Common Stock 338307101 154 1,593 SH   SOLE   1,593 0 0
Hasbro Inc Common Stock 418056107 188 2,092 SH   SOLE   2,092 0 0
HubSpot Inc Common Stock 443573100 121 357 SH   SOLE   357 0 0
Lululemon Athletica Inc Common Stock 550021109 137 469 SH   SOLE   469 0 0
Steven Madden Ltd Common Stock 556269108 165 4,442 SH   SOLE   4,442 0 0
MaxLinear Inc Common Stock 57776J100 116 2,918 SH   SOLE   2,918 0 0
McCormick & Co Inc/MD Common Stock 579780206 161 1,733 SH   SOLE   1,733 0 0
Momentive Global Inc Common Stock 60878Y108 128 10,521 SH   SOLE   10,521 0 0
Natura & Co Holding SA ADR 63884N108 112 15,956 SH   SOLE   15,956 0 0
NetApp Inc Common Stock 64110D104 148 2,055 SH   SOLE   2,055 0 0
Nutanix Inc Common Stock 67059N108 103 6,363 SH   SOLE   6,363 0 0
NVIDIA Corp Common Stock 67066G104 126,201 675,886 SH   SOLE   616,536 44,891 14,459
Omnicell Inc Common Stock 68213N109 149 1,341 SH   SOLE   1,341 0 0
PVH Corp Common Stock 693656100 158 2,229 SH   SOLE   2,229 0 0
Pearson PLC ADR 705015105 166 17,296 SH   SOLE   17,296 0 0
Qualys Inc Common Stock 74758T303 156 1,197 SH   SOLE   1,197 0 0
Rapid7 Inc Common Stock 753422104 109 1,540 SH   SOLE   1,540 0 0
Roper Technologies Inc Common Stock 776696106 161 364 SH   SOLE   364 0 0
Skyworks Solutions Inc Common Stock 83088M102 140 1,283 SH   SOLE   1,283 0 0
Sonoco Products Co Common Stock 835495102 161 2,748 SH   SOLE   2,748 0 0
Sony Group Corp ADR 835699307 158 1,679 SH   SOLE   1,679 0 0
Sonos Inc Common Stock 83570H108 135 6,109 SH   SOLE   6,109 0 0
Spectrum Brands Holdings Inc Common Stock 84790A105 169 1,930 SH   SOLE   1,930 0 0
Sprout Social Inc Common Stock 85209W109 108 2,124 SH   SOLE   2,124 0 0
Starbucks Corp Common Stock 855244109 148 1,888 SH   SOLE   1,888 0 0
TripAdvisor Inc Common Stock 896945201 158 6,366 SH   SOLE   6,366 0 0
VF Corp Common Stock 918204108 152 3,012 SH   SOLE   3,012 0 0
Atlassian Corp PLC Common Stock G06242104 104 584 SH   SOLE   584 0 0
Globant SA Common Stock L44385109 125 657 SH   SOLE   657 0 0
ASML Holding NV NY Reg Shrs N07059210 149 258 SH   SOLE   258 0 0
Elastic NV Common Stock N14506104 119 1,935 SH   SOLE   1,935 0 0
NU Holdings Ltd/Cayman Islands Common Stock G6683N103 18,637 4,891,686 SH   SOLE   4,891,686 0 0
Nurix Therapeutics Inc Common Stock 67080M103 7,857 778,725 SH   SOLE   778,725 0 0
XPeng Inc ADR 98422D105 22,246 946,658 SH   SOLE   946,658 0 0
Endeavor Group Holdings Inc Common Stock 29260Y109 10,826 476,501 SH   SOLE   476,501 0 0
Hyperfine Inc Common Stock 44916K106 2,890 1,000,000 SH   SOLE   1,000,000 0 0
Atlantic Coastal Acquisition C Common Stock 048453104 7,611 779,807 SH   SOLE   779,807 0 0
Fathom Digital Manufacturing C Common Stock 31189Y103 4,673 949,800 SH   SOLE   949,800 0 0
Shapeways Holdings Inc Common Stock 81947T102 4,398 2,697,863 SH   SOLE   2,697,863 0 0
Massivit 3D Printing Technolog Common Stock M6850N111 1,472 343,867 SH   SOLE   343,867 0 0
Global-e Online Ltd Common Stock M5216V106 15,651 812,173 SH   SOLE   812,173 0 0
Redhill Biopharma Ltd ADR 757468103 1,170 1,045,023 SH   SOLE   1,045,023 0 0
Gencell Ltd Common Stock M4R44V108 1,353 965,249 SH   SOLE   965,249 0 0
Arbe Robotics Ltd Common Stock M1R95N100 1,789 258,122 SH   SOLE   258,122 0 0
Cellebrite DI Ltd Common Stock M2197Q107 1,928 399,956 SH   SOLE   399,956 0 0
ironSource Ltd Common Stock M5R75Y101 1,493 516,478 SH   SOLE   516,478 0 0
Riskified Ltd Common Stock M8216R109 2,037 391,654 SH   SOLE   391,654 0 0
REE Automotive Ltd Common Stock M8287R103 1,696 1,059,878 SH   SOLE   1,059,878 0 0
Taboola.com Ltd Common Stock M8744T106 1,565 483,015 SH   SOLE   483,015 0 0
ATAI Life Sciences NV Common Stock N0731H103 6,444 1,619,035 SH   SOLE   1,619,035 0 0
Allegro MicroSystems Inc Common Stock 01749D105 156 6,073 SH   SOLE   6,073 0 0
Amkor Technology Inc Common Stock 031652100 160 7,841 SH   SOLE   7,841 0 0
BWX Technologies Inc Common Stock 05605H100 164 3,199 SH   SOLE   3,199 0 0
BioMarin Pharmaceutical Inc Common Stock 09061G101 167 2,228 SH   SOLE   2,228 0 0
Black Knight Inc Common Stock 09215C105 200 2,948 SH   SOLE   2,948 0 0
CME Group Inc Common Stock 12572Q105 143 718 SH   SOLE   718 0 0
Entegris Inc Common Stock 29362U104 145 1,308 SH   SOLE   1,308 0 0
Evotec SE Common Stock D1646D105 316 11,458 SH   SOLE   11,458 0 0
IPG Photonics Corp Common Stock 44980X109 166 1,572 SH   SOLE   1,572 0 0
KLA Corp Common Stock 482480100 171 469 SH   SOLE   469 0 0
Mercury Systems Inc Common Stock 589378108 159 2,663 SH   SOLE   2,663 0 0
Owens & Minor Inc Common Stock 690732102 135 3,858 SH   SOLE   3,858 0 0
RELX PLC Common Stock G7493L105 159 5,537 SH   SOLE   5,537 0 0
Rocket Lab USA Inc Common Stock 773122106 102 21,440 SH   SOLE   21,440 0 0
West Pharmaceutical Services I Common Stock 955306105 129 417 SH   SOLE   417 0 0
Allegion plc Common Stock G0176J109 174 1,558 SH   SOLE   1,558 0 0
Accenture PLC Common Stock G1151C101 152 510 SH   SOLE   510 0 0
Gates Industrial Corp PLC Common Stock G39108108 146 11,465 SH   SOLE   11,465 0 0
Matterport Inc Common Stock 577096100 5,698 1,037,911 SH   SOLE   1,037,911 0 0
NIO Inc ADR 62914V106 6,759 388,663 SH   SOLE   388,663 0 0
Straumann Holding AG Common Stock H8300N127 6,658 52,328 SH   SOLE   52,328 0 0
iShares Russell 1000 Growth ET ETP 464287614 137 574 SH   SOLE   574 0 0
Vanguard Growth ETF ETP 922908736 0 0 SH   SOLE   0 0 0
DraftKings Inc Common Stock 26142V105 342,487 25,275,813 SH   SOLE   23,366,954 1,395,866 512,993
General Motors Co Common Stock 37045V100 5,843 151,065 SH   SOLE   151,065 0 0
SPDR S&P 500 ETF Trust ETP 78462F103 32 78 SH   SOLE   78 0 0
Advanced Micro Devices Inc Common Stock 007903107 20 200 SH Put SOLE   200 0 0
ARK Genomic Revolution ETF ETP 00214Q302 71 2,200 SH Call SOLE   2,200 0 0
ARK Innovation ETF ETP 00214Q104 370 8,400 SH Call SOLE   8,400 0 0
Coinbase Global Inc Common Stock 19260Q107 172 2,200 SH Call SOLE   2,200 0 0
CRISPR Therapeutics AG Common Stock H17182108 75 1,300 SH Call SOLE   1,300 0 0
DraftKings Inc Common Stock 26142V105 134 9,900 SH Call SOLE   9,900 0 0
Intel Corp Common Stock 458140100 62 1,400 SH Put SOLE   1,400 0 0
Pacific Biosciences of Califor Common Stock 69404D108 41 7,200 SH Call SOLE   7,200 0 0
Roku Inc Common Stock 77543R102 114 1,200 SH Call SOLE   1,200 0 0
Block Inc Common Stock 852234103 236 2,700 SH Call SOLE   2,700 0 0
Teladoc Health Inc Common Stock 87918A105 20 600 SH Call SOLE   600 0 0
Tesla Inc Common Stock 88160R101 303 400 SH Call SOLE   400 0 0
Energy Select Sector SPDR Fund ETP 81369Y506 1,735 19,900 SH Put SOLE   19,900 0 0
Zoom Video Communications Inc Common Stock 98980L101 989 9,200 SH Call SOLE   9,200 0 0