The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete. | |||||||||||||||||
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UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 13F FORM 13F INFORMATION TABLE |
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| COLUMN 1 | COLUMN 2 | COLUMN 3 | COLUMN 4 | COLUMN 5 | COLUMN 6 | COLUMN 7 | COLUMN 8 | ||||
| VALUE | SHRS OR | SH/ | PUT/ | INVESTMENT | OTHER | VOTING AUTHORITY | |||||
| NAME OF ISSUER | TITLE OF CLASS | CUSIP | (x$1000) | PRN AMT | PRN | CALL | DISCRETION | MANAGER | SOLE | SHARED | NONE |
| AFFIMED N V | COM | N01045108 | 1,942 | 701,029 | SH | SOLE | 701,029 | 0 | 0 | ||
| AKOUOS INC | COM | 00973J101 | 1,800 | 383,784 | SH | SOLE | 383,784 | 0 | 0 | ||
| ALNYLAM PHARMACEUTICALS INC | COM | 02043Q107 | 925 | 50,000 | SH | Put | SOLE | 50,000 | 0 | 0 | |
| AMARIN CORP PLC | SPONS ADR NEW | 023111206 | 5,975 | 4,009,893 | SH | SOLE | 4,009,893 | 0 | 0 | ||
| AMICUS THERAPEUTICS INC | COM | 03152W109 | 9,666 | 900,000 | SH | SOLE | 900,000 | 0 | 0 | ||
| BIOCRYST PHARMACEUTICALS INC | COM | 09058V103 | 9,909 | 936,563 | SH | SOLE | 936,563 | 0 | 0 | ||
| BIOGEN INC | COM | 09062X103 | 16,101 | 78,951 | SH | SOLE | 78,951 | 0 | 0 | ||
| BURNING ROCK BIOTECH LTD | SPONSORED ADS | 12233L107 | 12,513 | 4,300,000 | SH | SOLE | 4,300,000 | 0 | 0 | ||
| CABALETTA BIO INC | COM | 12674W109 | 580 | 546,800 | SH | SOLE | 546,800 | 0 | 0 | ||
| CATALYST BIOSCIENCES INC | COM NEW | 14888D208 | 166 | 93,434 | SH | SOLE | 93,434 | 0 | 0 | ||
| CELLDEX THERAPEUTICS INC NEW | COM NEW | 15117B202 | 30,526 | 1,132,259 | SH | SOLE | 1,132,259 | 0 | 0 | ||
| CELLDEX THERAPEUTICS INC NEW | COM NEW | 15117B202 | 2,476 | 246,400 | SH | Call | SOLE | 246,400 | 0 | 0 | |
| CENTESSA PHARMACEUTICALS PLC | SPONSORED ADS | 152309100 | 3,691 | 757,848 | SH | SOLE | 757,848 | 0 | 0 | ||
| COGENT BIOSCIENCES INC | COM | 19240Q201 | 9,020 | 1,000,000 | SH | SOLE | 1,000,000 | 0 | 0 | ||
| CONCERT PHARMACEUTICALS INC | COM | 206022105 | 4,210 | 1,000,000 | SH | SOLE | 1,000,000 | 0 | 0 | ||
| CONNECT BIOPHARMA HLDGS LTD | ADS | 207523101 | 643 | 739,649 | SH | SOLE | 739,649 | 0 | 0 | ||
| FATE THERAPEUTICS INC | COM | 31189P102 | 2,009 | 81,064 | SH | SOLE | 81,064 | 0 | 0 | ||
| GLOBAL BLOOD THERAPEUTICS IN | COM | 37890U108 | 70,290 | 2,200,000 | SH | SOLE | 2,200,000 | 0 | 0 | ||
| GOSSAMER BIO INC | COM | 38341P102 | 19,673 | 2,350,448 | SH | SOLE | 2,350,448 | 0 | 0 | ||
| KARUNA THERAPEUTICS INC | COM | 48576A100 | 578 | 38,900 | SH | Put | SOLE | 38,900 | 0 | 0 | |
| LIQUIDIA CORPORATION | COM NEW | 53635D202 | 6,543 | 1,500,718 | SH | SOLE | 1,500,718 | 0 | 0 | ||
| MERUS N V | COM | N5749R100 | 2,346 | 103,627 | SH | SOLE | 103,627 | 0 | 0 | ||
| NATERA INC | COM | 632307104 | 43,912 | 1,239,047 | SH | SOLE | 1,239,047 | 0 | 0 | ||
| NEOLEUKIN THERAPEUTICS INC | COM | 64049K104 | 128 | 124,701 | SH | SOLE | 124,701 | 0 | 0 | ||
| OLEMA PHARMACEUTICALS INC | COM | 68062P106 | 1,014 | 249,229 | SH | SOLE | 249,229 | 0 | 0 | ||
| PUMA BIOTECHNOLOGY INC | COM | 74587V107 | 1,653 | 579,915 | SH | SOLE | 579,915 | 0 | 0 | ||
| SERES THERAPEUTICS INC | COM | 81750R102 | 887 | 258,647 | SH | SOLE | 258,647 | 0 | 0 | ||
| SYNDAX PHARMACEUTICALS INC | COM | 87164F105 | 48,335 | 2,512,240 | SH | SOLE | 2,512,240 | 0 | 0 | ||
| TRAVERE THERAPEUTICS INC | COM | 89422G107 | 29,928 | 1,235,151 | SH | SOLE | 1,235,151 | 0 | 0 | ||
| VAXCYTE INC | COM | 92243G108 | 15,749 | 723,781 | SH | SOLE | 723,781 | 0 | 0 | ||
| VERA THERAPEUTICS INC | CL A | 92337R101 | 20,724 | 1,522,712 | SH | SOLE | 1,522,712 | 0 | 0 | ||
| VIRIDIAN THERAPEUTICS INC | COM | 92790C104 | 6,828 | 590,143 | SH | SOLE | 590,143 | 0 | 0 | ||
| WAVE LIFE SCIENCES LTD | SHS | Y95308105 | 5,514 | 1,696,735 | SH | SOLE | 1,696,735 | 0 | 0 | ||
| XENON PHARMACEUTICALS INC | COM | 98420N105 | 5,324 | 175,000 | SH | SOLE | 175,000 | 0 | 0 | ||