The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ABCAM PLC ADS 000380204 23,432 1,620,500 SH   SOLE   1,620,500 0 0
ACADIA HEALTHCARE COMPANY IN COM 00404A109 50,959 753,500 SH   SOLE   753,500 0 0
ACCOLADE INC COM 00437E102 16,280 2,200,000 SH   SOLE   2,200,000 0 0
ACELRX PHARMACEUTICALS INC COM 00444T100 1,546 6,329,202 SH   SOLE   6,329,202 0 0
ACLARIS THERAPEUTICS INC COM 00461U105 54,823 3,927,149 SH   SOLE   3,927,149 0 0
ADAPTIMMUNE THERAPEUTICS PLC SPONDS ADR 00653A107 4,008 2,357,544 SH   SOLE   2,357,544 0 0
AEGLEA BIOTHERAPEUTICS INC COM 00773J103 1,552 3,072,034 SH   SOLE   3,072,034 0 0
AGILON HEALTH INC COM 00857U107 167,676 7,681,000 SH   SOLE   7,681,000 0 0
AGIOS PHARMACEUTICALS INC COM 00847X104 64,924 2,928,458 SH   SOLE   2,928,458 0 0
AKERO THERAPEUTICS INC COM 00973Y108 6,421 679,514 SH   SOLE   679,514 0 0
ALIGN TECHNOLOGY INC COM 016255101 83,900 354,500 SH   SOLE   354,500 0 0
ALNYLAM PHARMACEUTICALS INC COM 02043Q107 48,495 332,500 SH   SOLE   332,500 0 0
AMICUS THERAPEUTICS INC COM 03152W109 10,874 1,012,506 SH   SOLE   1,012,506 0 0
AMRYT PHARMA PLC SPONSORED ADS 03217L106 9,175 1,312,625 SH   SOLE   1,312,625 0 0
AMYLYX PHARMACEUTICALS INC COM 03237H101 18,761 974,107 SH   SOLE   974,107 0 0
ANAPTYSBIO INC COM 032724106 11,618 572,300 SH   SOLE   572,300 0 0
APPLIED THERAPEUTICS INC COM 03828A101 665 701,680 SH   SOLE   701,680 0 0
ARGENX SE SPONSORED ADR 04016X101 132,608 350,000 SH   SOLE   350,000 0 0
ARVINAS INC COM 04335A105 11,789 280,100 SH   SOLE   280,100 0 0
ASCENDIS PHARMA A/S SPONSORED ADR 04351P101 39,554 425,500 SH   SOLE   425,500 0 0
ATRECA INC CL A COM 04965G109 828 462,530 SH   SOLE   462,530 0 0
AURA BIOSCIENCES INC COM 05153U107 14,295 1,008,814 SH   SOLE   1,008,814 0 0
AURINIA PHARMACEUTICALS INC COM 05156V102 8,192 815,126 SH   SOLE   815,126 0 0
AZENTA INC COM 114340102 11,680 162,000 SH   SOLE   162,000 0 0
BAXTER INTL INC COM 071813109 45,064 701,600 SH   SOLE   701,600 0 0
BCLS ACQUISITION CORP COM CL A G0904B105 3,059 309,000 SH   SOLE   309,000 0 0
BEAM THERAPEUTICS INC COM 07373V105 4,313 111,430 SH   SOLE   111,430 0 0
BIOCRYST PHARMACEUTICALS INC COM 09058V103 15,458 1,461,091 SH   SOLE   1,461,091 0 0
BIOMARIN PHARMACEUTICAL INC COM 09061G101 21,919 264,500 SH   SOLE   264,500 0 0
BIOMEA FUSION INC COM 09077A106 13,007 1,085,740 SH   SOLE   1,085,740 0 0
BLUEPRINT MEDICINES CORP COM 09627Y109 49,458 979,174 SH   SOLE   979,174 0 0
CELLDEX THERAPEUTICS INC NEW COM NEW 15117B202 9,044 335,477 SH   SOLE   335,477 0 0
CEREVEL THERAPEUTICS HLDNG I COM 15678U128 46,723 1,767,141 SH   SOLE   1,767,141 0 0
CHINOOK THERAPEUTICS INC COM 16961L106 8,876 507,512 SH   SOLE   507,512 0 0
CINCOR PHARMA INC COM 17240Y109 19,239 1,021,159 SH   SOLE   1,021,159 0 0
COLLEGIUM PHARMACEUTICAL INC COM 19459J104 12,847 725,000 SH   SOLE   725,000 0 0
COMPASS THERAPEUTICS INC COM 20454B104 14,119 5,328,088 SH   SOLE   5,328,088 0 0
COMPUGEN LTD ORD M25722105 2,386 1,289,990 SH   SOLE   1,289,990 0 0
CONMED CORP COM 207410101 21,354 223,000 SH   SOLE   223,000 0 0
COVETRUS INC COM 22304C100 34,835 1,678,800 SH   SOLE   1,678,800 0 0
CYTOKINETICS INC COM NEW 23282W605 15,716 400,000 SH   SOLE   400,000 0 0
DESIGN THERAPEUTICS INC COM 25056L103 6,445 460,391 SH   SOLE   460,391 0 0
DEXCOM INC COM 252131107 35,238 472,800 SH   SOLE   472,800 0 0
DYNAVAX TECHNOLOGIES CORP COM NEW 268158201 21,170 1,681,458 SH   SOLE   1,681,458 0 0
EDAP TMS S A SPONSORED ADR 268311107 6,188 910,000 SH   SOLE   910,000 0 0
EDWARDS LIFESCIENCES CORP COM 28176E108 57,244 602,000 SH   SOLE   602,000 0 0
EPIZYME INC COM 29428V104 11,004 7,485,543 SH   SOLE   7,485,543 0 0
EQRX INC COM 26886C107 4,690 1,000,000 SH   SOLE   1,000,000 0 0
ESSA PHARMA INC COM NEW 29668H708 1,654 524,944 SH   SOLE   524,944 0 0
EVOLENT HEALTH INC CL A 30050B101 84,084 2,738,000 SH   SOLE   2,738,000 0 0
EXACT SCIENCES CORP COM 30063P105 22,559 572,700 SH   SOLE   572,700 0 0
FATE THERAPEUTICS INC COM 31189P102 2,726 110,000 SH   SOLE   110,000 0 0
FRESHPET INC COM 358039105 33,085 637,600 SH   SOLE   637,600 0 0
F-STAR THERAPEUTICS INC COM 30315R107 4,707 751,889 SH   SOLE   751,889 0 0
FULCRUM THERAPEUTICS INC COM 359616109 1,884 384,590 SH   SOLE   384,590 0 0
FUSION PHARMACEUTICALS INC COM 36118A100 2,017 809,854 SH   SOLE   809,854 0 0
GAMIDA CELL LTD SHS M47364100 3,850 2,175,000 SH   SOLE   2,175,000 0 0
GOSSAMER BIO INC NOTE 5.000% 6/0 38341PAA0 7,156 9,573,000 PRN   SOLE   9,573,000 0 0
GUARDANT HEALTH INC COM 40131M109 8,068 200,000 SH   SOLE   200,000 0 0
HEALTH CATALYST INC COM 42225T107 13,699 945,400 SH   SOLE   945,400 0 0
HORIZON THERAPEUTICS PUB L SHS G46188101 59,501 746,000 SH   SOLE   746,000 0 0
HUMANA INC COM 444859102 199,565 426,358 SH   SOLE   426,358 0 0
ICOSAVAX INC COM 45114M109 4,364 761,557 SH   SOLE   761,557 0 0
IDEXX LABS INC COM 45168D104 78,476 223,750 SH   SOLE   223,750 0 0
IMARA INC COM 45249V107 1,028 842,402 SH   SOLE   842,402 0 0
IMMATICS N.V SHS N44445109 9,825 1,127,970 SH   SOLE   1,127,970 0 0
IMMUNOCORE HLDGS PLC ADS 45258D105 99,679 2,671,652 SH   SOLE   2,671,652 0 0
INOZYME PHARMA INC COM 45790W108 12,593 2,640,056 SH   SOLE   2,640,056 0 0
INSULET CORP COM 45784P101 109,406 502,000 SH   SOLE   502,000 0 0
INTUITIVE SURGICAL INC COM NEW 46120E602 59,912 298,500 SH   SOLE   298,500 0 0
INVITAE CORP COM 46185L103 8,527 3,494,721 SH   SOLE   3,494,721 0 0
IRHYTHM TECHNOLOGIES INC COM 450056106 29,168 270,000 SH   SOLE   270,000 0 0
JIYA ACQUISITION CORP COM CL A 47760M102 2,037 206,200 SH   SOLE   206,200 0 0
KARUNA THERAPEUTICS INC COM 48576A100 55,904 441,893 SH   SOLE   441,893 0 0
KINNATE BIOPHARMA INC COM 49705R105 7,798 618,384 SH   SOLE   618,384 0 0
KYMERA THERAPEUTICS INC COM 501575104 15,277 775,879 SH   SOLE   775,879 0 0
LEAP THERAPEUTICS INC COM 52187K101 4,201 3,652,947 SH   SOLE   3,652,947 0 0
LEGEND BIOTECH CORP SPONSORED ADS 52490G102 19,556 355,567 SH   SOLE   355,567 0 0
LIFESTANCE HEALTH GROUP INC COM 53228F101 11,120 2,000,000 SH   SOLE   2,000,000 0 0
MACROGENICS INC COM 556099109 2,816 954,728 SH   SOLE   954,728 0 0
MADRIGAL PHARMACEUTICALS INC COM 558868105 22,726 317,485 SH   SOLE   317,485 0 0
MEREO BIOPHARMA GROUP PLC ADS 589492107 6,978 6,230,275 SH   SOLE   6,230,275 0 0
MERSANA THERAPEUTICS INC COM 59045L106 18,831 4,075,958 SH   SOLE   4,075,958 0 0
MIRATI THERAPEUTICS INC COM 60468T105 56,723 844,977 SH   SOLE   844,977 0 0
MIRUM PHARMACEUTICALS INC COM 604749101 33,427 1,717,733 SH   SOLE   1,717,733 0 0
NEUROCRINE BIOSCIENCES INC NOTE 2.250% 5/1 64125CAD1 1,328 1,000,000 PRN   SOLE   1,000,000 0 0
NEUROCRINE BIOSCIENCES INC COM 64125C109 109,421 1,122,500 SH   SOLE   1,122,500 0 0
NEVRO CORP NOTE 2.750% 4/0 64157FAC7 466 500,000 PRN   SOLE   500,000 0 0
NEVRO CORP COM 64157F103 33,894 773,300 SH   SOLE   773,300 0 0
NKARTA INC COM 65487U108 7,593 616,277 SH   SOLE   616,277 0 0
NOVAVAX INC COM NEW 670002401 24,434 475,100 SH   SOLE   475,100 0 0
NOVOCURE LTD ORD SHS G6674U108 12,163 175,000 SH   SOLE   175,000 0 0
NUVATION BIO INC *W EXP 07/07/202 67080N119 38 134,028 SH   SOLE   134,028 0 0
OLINK HLDG AB SPONSORED ADS 680710100 18,723 1,231,800 SH   SOLE   1,231,800 0 0
ORION ACQUISITION CORP UNIT 02/19/2026 68626A207 9,810 1,000,000 SH   SOLE   1,000,000 0 0
PACIRA BIOSCIENCES INC COM 695127100 59,320 1,017,500 SH   SOLE   1,017,500 0 0
PARATEK PHARMACEUTICALS INC COM 699374302 3,347 1,734,037 SH   SOLE   1,734,037 0 0
PENUMBRA INC COM 70975L107 49,995 401,500 SH   SOLE   401,500 0 0
PHASEBIO PHARMACEUTICALS INC COM 717224109 1,665 2,774,869 SH   SOLE   2,774,869 0 0
PHREESIA INC COM 71944F106 32,468 1,298,200 SH   SOLE   1,298,200 0 0
PRELUDE THERAPEUTICS INC COM 74065P101 1,926 368,959 SH   SOLE   368,959 0 0
PROMETHEUS BIOSCIENCES INC COM 74349U108 18,194 644,507 SH   SOLE   644,507 0 0
PROTHENA CORP PLC SHS G72800108 18,420 678,462 SH   SOLE   678,462 0 0
PULMONX CORP COM 745848101 10,339 702,400 SH   SOLE   702,400 0 0
RADIUS HEALTH INC NOTE 3.000% 9/0 750469AA6 1,473 1,500,000 PRN   SOLE   1,500,000 0 0
RELAY THERAPEUTICS INC COM 75943R102 10,356 618,267 SH   SOLE   618,267 0 0
RENEO PHARMACEUTICALS INC COM 75974E103 3,029 1,143,185 SH   SOLE   1,143,185 0 0
RHYTHM PHARMACEUTICALS INC COM 76243J105 5,824 1,403,298 SH   SOLE   1,403,298 0 0
SAREPTA THERAPEUTICS INC COM 803607100 32,083 428,000 SH   SOLE   428,000 0 0
SEAGEN INC COM 81181C104 48,128 272,000 SH   SOLE   272,000 0 0
SELECT SECTOR SPDR TR SBI HEALTHCARE 81369Y209 25,648 200,000 SH   SOLE   200,000 0 0
SHOCKWAVE MED INC COM 82489T104 45,976 240,500 SH   SOLE   240,500 0 0
SIERRA ONCOLOGY INC COM NEW 82640U404 64,601 1,174,786 SH   SOLE   1,174,786 0 0
SPERO THERAPEUTICS INC COM 84833T103 571 770,710 SH   SOLE   770,710 0 0
SPRUCE BIOSCIENCES INC COM 85209E109 2,823 1,622,689 SH   SOLE   1,622,689 0 0
TEMPEST THERAPEUTICS INC COM 87978U108 1,771 823,654 SH   SOLE   823,654 0 0
THERAVANCE BIOPHARMA INC NOTE 3.250%11/0 88339KAA0 1,381 1,500,000 PRN   SOLE   1,500,000 0 0
THESEUS PHARMACEUTICALS INC COM 88369M101 2,418 437,329 SH   SOLE   437,329 0 0
TRAVERE THERAPEUTICS INC NOTE 2.500% 9/1 761299AB2 3,221 3,250,000 PRN   SOLE   3,250,000 0 0
TRAVERE THERAPEUTICS INC COM 89422G107 23,058 951,650 SH   SOLE   951,650 0 0
TURNING POINT THERAPEUTICS I COM 90041T108 20,452 271,787 SH   SOLE   271,787 0 0
ULTRAGENYX PHARMACEUTICAL IN COM 90400D108 65,210 1,093,030 SH   SOLE   1,093,030 0 0
UNITEDHEALTH GROUP INC COM 91324P102 137,910 268,500 SH   SOLE   268,500 0 0
VERVE THERAPEUTICS INC COM 92539P101 7,702 504,037 SH   SOLE   504,037 0 0
VIGIL NEUROSCIENCE INC COM 92673K108 1,218 471,958 SH   SOLE   471,958 0 0
VINCERX PHARMA INC COM NEW 92731L106 1,075 814,194 SH   SOLE   814,194 0 0
WARBY PARKER INC CL A COM 93403J106 14,340 1,273,500 SH   SOLE   1,273,500 0 0
WEST PHARMACEUTICAL SVSC INC COM 955306105 33,563 111,000 SH   SOLE   111,000 0 0
XENON PHARMACEUTICALS INC COM 98420N105 34,180 1,123,604 SH   SOLE   1,123,604 0 0
XILIO THERAPEUTICS INC COM 98422T100 3,980 1,362,878 SH   SOLE   1,362,878 0 0
ZAI LAB LTD ADR 98887Q104 42,167 1,215,900 SH   SOLE   1,215,900 0 0