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The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
1LIFE HEALTHCARE INC NOTE 3.000% 6/1 68269GAB3 40,222 48,599,000 PRN   DFND 1 48,599,000 0 0
89BIO INC COM 282559103 1,630 506,100 SH   DFND 1 506,100 0 0
ACCOLADE INC NOTE 0.500% 4/0 00437EAB8 59,134 92,624,000 PRN   DFND 1 92,624,000 0 0
ACUTUS MED INC COM 005111109 2,966 2,648,386 SH   DFND 1 2,648,386 0 0
ADAPTHEALTH CORP COMMON STOCK 00653Q102 201,160 11,150,797 SH   DFND 1 11,150,797 0 0
AERIE PHARMACEUTICALS INC NOTE 1.500%10/0 00771VAB4 133,036 157,390,000 PRN   DFND 1 157,390,000 0 0
AERIE PHARMACEUTICALS INC COM 00771V108 35,213 4,695,020 SH   DFND 1 4,695,020 0 0
ALECTOR INC COM 014442107 10,721 1,055,192 SH   DFND 1 1,055,192 0 0
ALPHATEC HLDGS INC COM NEW 02081G201 15,830 2,420,547 SH   DFND 1 2,420,547 0 0
AMEDISYS INC COM 023436108 20,919 199,000 SH   DFND 1 199,000 0 0
AN2 THERAPEUTICS INC COM 037326105 5,553 716,538 SH   DFND 1 716,538 0 0
ANAPTYSBIO INC COM 032724106 15,672 772,000 SH   DFND 1 772,000 0 0
ANNEXON INC COM 03589W102 2,201 583,913 SH   DFND 1 583,913 0 0
APELLIS PHARMACEUTICALS INC NOTE 3.500% 9/1 03753UAB2 76,456 51,885,000 PRN   DFND 1 51,885,000 0 0
APOLLO ENDOSURGERY INC COM 03767D108 6,388 1,750,000 SH   DFND 1 1,750,000 0 0
BELLUS HEALTH INC NEW COM NEW 07987C204 22,851 2,473,000 SH   DFND 1 2,473,000 0 0
BENEFITFOCUS INC NOTE 1.250%12/1 08180DAB2 5,907 6,500,000 PRN   DFND 1 6,500,000 0 0
BIOGEN INC COM 09062X103 101,970 500,000 SH Call DFND 1 500,000 0 0
BROOKDALE SR LIVING INC COM 112463104 39,010 8,592,461 SH   DFND 1 8,592,461 0 0
BUTTERFLY NETWORK INC *W EXP 02/12/202 124155110 296 733,333 SH   DFND 1 733,333 0 0
CABALETTA BIO INC COM 12674W109 492 464,252 SH   DFND 1 464,252 0 0
CAREMAX INC COM CL A 14171W103 57,576 15,861,090 SH   DFND 1 15,861,090 0 0
CAREMAX INC *W EXP 06/08/202 14171W111 484 672,000 SH   DFND 1 672,000 0 0
CENTENE CORP DEL COM 15135B101 48,972 578,800 SH   DFND 1 578,800 0 0
COGENT BIOSCIENCES INC COM 19240Q201 53,009 5,876,805 SH   DFND 1 5,876,805 0 0
CYTOKINETICS INC COM NEW 23282W605 45,589 1,160,315 SH   DFND 1 1,160,315 0 0
DA32 LIFE SCNCE TEC ACQSTN C CLASS A COM 23312M106 15,504 1,600,000 SH   DFND 1 1,600,000 0 0
DAY ONE BIOPHARMACEUTICALS I COM 23954D109 62,867 3,512,123 SH   DFND 1 3,512,123 0 0
DECIPHERA PHARMACEUTICALS IN COM 24344T101 82,200 6,250,964 SH   DFND 1 6,250,964 0 0
DELCATH SYS INC COM NEW 24661P807 1,995 500,000 SH   DFND 1 500,000 0 0
DYNAVAX TECHNOLOGIES CORP NOTE 2.500% 5/1 268158AD4 44,735 30,000,000 PRN   DFND 1 30,000,000 0 0
EDGEWISE THERAPEUTICS INC COM 28036F105 31,308 3,933,137 SH   DFND 1 3,933,137 0 0
ENVISTA HOLDINGS CORPORATION NOTE 2.375% 6/0 29415FAB0 100,380 52,500,000 PRN   DFND 1 52,500,000 0 0
EUCRATES BIOMEDICAL ACQU COR *W EXP 10/23/202 G3141W122 22 333,333 SH   DFND 1 333,333 0 0
EUCRATES BIOMEDICAL ACQU COR UNIT 10/23/2027 G3141W114 0 1 SH   DFND 1 1 0 0
EUCRATES BIOMEDICAL ACQU COR SHS G3141W106 9,900 999,999 SH   DFND 1 999,999 0 0
EVOLUS INC COM 30052C107 42,140 3,632,751 SH   DFND 1 3,632,751 0 0
FOGHORN THERAPEUTICS INC COM 344174107 10,574 777,525 SH   DFND 1 777,525 0 0
GUARDANT HEALTH INC NOTE 11/1 40131MAB5 56,684 89,036,000 PRN   DFND 1 89,036,000 0 0
GILEAD SCIENCES INC COM 375558103 95,969 1,552,639 SH   DFND 1 1,552,639 0 0
GLAUKOS CORP NOTE 2.750% 6/1 377322AB8 324,465 271,752,000 PRN   DFND 1 271,752,000 0 0
GLAUKOS CORP COM 377322102 47,215 1,039,514 SH   DFND 1 1,039,514 0 0
GRAYBUG VISION INC COM SHS 38942Q103 5,757 5,281,713 SH   DFND 1 5,281,713 0 0
HEALTH CATALYST INC NOTE 2.500% 4/1 42225TAB3 13,452 15,000,000 PRN   DFND 1 15,000,000 0 0
HILLEVAX INC COM 43157M102 28,614 2,617,948 SH   DFND 1 2,617,948 0 0
HORIZON THERAPEUTICS PUB L SHS G46188101 24,965 313,000 SH   DFND 1 313,000 0 0
IGNYTE ACQUISITION CORP *W EXP 01/05/202 45175H114 76 362,500 SH   DFND 1 362,500 0 0
IGNYTE ACQUISITION CORP COM 45175H106 7,149 725,000 SH   DFND 1 725,000 0 0
IMMUNOGEN INC COM 45253H101 67,592 15,020,490 SH   DFND 1 15,020,490 0 0
INOZYME PHARMA INC COM 45790W108 12,862 2,696,372 SH   DFND 1 2,696,372 0 0
INSMED INC NOTE 1.750% 1/1 457669AA7 70,460 75,000,000 PRN   DFND 1 75,000,000 0 0
INSMED INC COM PAR $.01 457669307 18,941 960,484 SH   DFND 1 960,484 0 0
INSULET CORP NOTE 0.375% 9/0 45784PAK7 66,018 57,581,000 PRN   DFND 1 57,581,000 0 0
INTERCEPT PHARMACEUTICALS IN NOTE 3.250% 7/0 45845PAA6 56,158 57,791,000 PRN   DFND 1 57,791,000 0 0
INVITAE CORP NOTE 2.000% 9/0 46185LAB9 163,025 206,873,000 PRN   DFND 1 206,873,000 0 0
IONIS PHARMACEUTICALS INC NOTE 4/0 462222AD2 116,991 127,800,000 PRN   DFND 1 127,800,000 0 0
IVERIC BIO INC COM 46583P102 50,159 5,214,000 SH   DFND 1 5,214,000 0 0
KEZAR LIFE SCIENCES INC COM 49372L100 11,735 1,419,000 SH   DFND 1 1,419,000 0 0
KINNATE BIOPHARMA INC COM 49705R105 3,153 250,000 SH   DFND 1 250,000 0 0
KURA ONCOLOGY INC COM 50127T109 48,153 2,627,000 SH   DFND 1 2,627,000 0 0
LARIMAR THERAPEUTICS INC COM 517125100 11,427 5,830,249 SH   DFND 1 5,830,249 0 0
LIVONGO HEALTH INC NOTE 0.875% 6/0 539183AA1 42,380 50,000,000 PRN   DFND 1 50,000,000 0 0
MEDAVAIL HOLDINGS INC COM 58406B103 1,280 836,626 SH   DFND 1 836,626 0 0
MEDTECH ACQUISITION CORP UNIT 12/18/2025 58507N204 0 1 SH   DFND 1 1 0 0
MEDTECH ACQUISITION CORP COM CL A 58507N105 9,845 999,999 SH   DFND 1 999,999 0 0
MEDTECH ACQUISITION CORP *W EXP 12/22/202 58507N113 28 333,333 SH   DFND 1 333,333 0 0
MERUS N V COM N5749R100 44,961 1,985,924 SH   DFND 1 1,985,924 0 0
MIRUM PHARMACEUTICALS INC COM 604749101 63,137 3,244,434 SH   DFND 1 3,244,434 0 0
MOLINA HEALTHCARE INC COM 60855R100 46,695 167,000 SH   DFND 1 167,000 0 0
NATERA INC NOTE 2.250% 5/0 632307AB0 111,924 90,638,000 PRN   DFND 1 90,638,000 0 0
NEOGENOMICS INC NOTE 1.250% 5/0 64049MAA8 5,443 6,500,000 PRN   DFND 1 6,500,000 0 0
NEUROCRINE BIOSCIENCES INC COM 64125C109 196,199 2,012,714 SH   DFND 1 2,012,714 0 0
NEVRO CORP NOTE 2.750% 4/0 64157FAC7 57,724 61,000,000 PRN   DFND 1 61,000,000 0 0
NKARTA INC COM 65487U108 7,392 600,000 SH   DFND 1 600,000 0 0
NOVAVAX INC NOTE 3.750% 2/0 670002AB0 24,855 25,000,000 PRN   DFND 1 25,000,000 0 0
NUVALENT INC COM 670703107 262,264 19,341,024 SH   DFND 1 19,341,024 0 0
NUVASIVE INC NOTE 0.375% 3/1 670704AJ4 71,655 80,000,000 PRN   DFND 1 80,000,000 0 0
NUVASIVE INC NOTE 1.000% 6/0 670704AL9 93,615 96,966,000 PRN   DFND 1 96,966,000 0 0
NUVATION BIO INC *W EXP 07/07/202 67080N119 47 166,666 SH   DFND 1 166,666 0 0
NYXOAH S A SHS B6S7WD106 4,188 455,262 SH   DFND 1 455,262 0 0
ONCORUS INC COM 68236R103 3,968 3,148,977 SH   DFND 1 3,148,977 0 0
THE ONCOLOGY INSTITUTE INC *W EXP 11/15/202 68236X118 625 1,250,000 SH   DFND 1 1,250,000 0 0
THE ONCOLOGY INSTITUTE INC COM 68236X100 17,118 3,383,099 SH   DFND 1 3,383,099 0 0
ORCHARD THERAPEUTICS PLC ADS 68570P101 4,060 6,949,416 SH   DFND 1 6,949,416 0 0
ORGANOGENESIS HLDGS INC COM 68621F102 21,705 4,447,740 SH   DFND 1 4,447,740 0 0
ORION ACQUISITION CORP *W EXP 02/19/202 68626A116 11 125,000 SH   DFND 1 125,000 0 0
ORION ACQUISITION CORP COM CL A 68626A108 4,900 500,000 SH   DFND 1 500,000 0 0
OAK STR HEALTH INC NOTE 3/1 67181AAB3 48,551 68,000,000 SH   DFND 1 68,000,000 0 0
OUTSET MED INC COM 690145107 5,953 400,622 SH   DFND 1 400,622 0 0
PACIRA BIOSCIENCES INC COM 695127100 17,024 292,000 SH   DFND 1 292,000 0 0
PACIRA BIOSCIENCES INC NOTE 0.750% 8/0 695127AF7 84,967 81,600,000 PRN   DFND 1 81,600,000 0 0
PEPGEN INC COM 713317105 9,470 953,626 SH   DFND 1 953,626 0 0
PHARVARIS N V COM N69605108 26,307 1,190,343 SH   DFND 1 1,190,343 0 0
PHREESIA INC COM 71944F106 21,436 857,115 SH   DFND 1 857,115 0 0
PROFOUND MED CORP COM NEW 74319B502 12,494 1,713,797 SH   DFND 1 1,713,797 0 0
PTC THERAPEUTICS INC NOTE 3.000% 8/1 69366JAB7 25,518 25,417,000 PRN   DFND 1 25,417,000 0 0
PTC THERAPEUTICS INC NOTE 1.500% 9/1 69366JAD3 33,439 32,000,000 PRN   DFND 1 32,000,000 0 0
PULMONX CORP COM 745848101 51,018 3,465,901 SH   DFND 1 3,465,901 0 0
QUANTUM SI INC COM CL A 74765K105 3,248 1,400,000 SH   DFND 1 1,400,000 0 0
QUANTUM SI INC *W EXP 06/10/202 74765K113 188 333,333 SH   DFND 1 333,333 0 0
REVOLUTION HEALTHCAR AQ CORP CLASS A COM 76155Y108 9,770 1,000,000 SH   DFND 1 1,000,000 0 0
REVOLUTION HEALTHCAR AQ CORP *W EXP 12/31/202 76155Y116 49 200,000 SH   DFND 1 200,000 0 0
REVOLUTION MEDICINES INC COM 76155X100 17,377 891,587 SH   DFND 1 891,587 0 0
RHYTHM PHARMACEUTICALS INC COM 76243J105 1,208 291,005 SH   DFND 1 291,005 0 0
ROIVANT SCIENCES LTD *W EXP 09/30/202 G76279119 600 1,000,000 SH   DFND 1 1,000,000 0 0
SARISSA CAPITAL ACQUISITN CO UNIT 10/23/2027 G7823W128 0 1 SH   DFND 1 1 0 0
SARISSA CAPITAL ACQUISITN CO CL A G7823W102 9,890 999,999 SH   DFND 1 999,999 0 0
SARISSA CAPITAL ACQUISITN CO *W EXP 10/23/202 G7823W110 33 333,333 SH   DFND 1 333,333 0 0
SEMA4 HOLDINGS CORP COM CL A 81663L101 23,749 18,848,488 SH   DFND 1 18,848,488 0 0
SENIOR CONNECT ACQUISITN COR *W EXP 12/31/202 81723H116 35 500,000 SH   DFND 1 500,000 0 0
SENIOR CONNECT ACQUISITN COR COM CL A 81723H108 9,840 1,000,000 SH   DFND 1 1,000,000 0 0
SILK RD MED INC COM 82710M100 97,412 2,676,891 SH   DFND 1 2,676,891 0 0
SINGULAR GENOMICS SYSTEMS IN COM 82933R100 24,205 6,336,330 SH   DFND 1 6,336,330 0 0
SOMALOGIC INC *W EXP 08/31/202 83444K113 91 120,000 SH   DFND 1 120,000 0 0
SAREPTA THERAPEUTICS INC DBCV 1.500%11/1 803607AB6 111,766 88,657,000 SH   DFND 1 88,657,000 0 0
SURROZEN INC *W EXP 08/01/203 86889P117 32 166,666 SH   DFND 1 166,666 0 0
SYNDAX PHARMACEUTICALS INC COM 87164F105 21,378 1,111,111 SH   DFND 1 1,111,111 0 0
TABULA RASA HEALTHCARE INC NOTE 1.750% 2/1 873379AA9 97,174 144,516,000 PRN   DFND 1 144,516,000 0 0
TARSUS PHARMACEUTICALS INC COM 87650L103 19,334 1,324,214 SH   DFND 1 1,324,214 0 0
TG THERAPEUTICS INC COM 88322Q108 11,379 2,677,500 SH   DFND 1 2,677,500 0 0
TURMERIC ACQUISITION CORP *W EXP 10/08/202 G9127T124 19 250,000 SH   DFND 1 250,000 0 0
TURMERIC ACQUISITION CORP CL A G9127T108 7,448 750,000 SH   DFND 1 750,000 0 0
VIATRIS INC COM 92556V106 216,454 20,673,700 SH   DFND 1 20,673,700 0 0
WEREWOLF THERAPEUTICS INC COM 95075A107 3,919 958,125 SH   DFND 1 958,125 0 0
WINDTREE THERAPEUTICS INC COM 97382D303 8 20,148 SH   DFND 1 20,148 0 0
XERIS BIOPHARMA HOLDINGS INC NOTE 5.000% 7/1 98422LAA5 17,607 18,000,000 PRN   DFND 1 18,000,000 0 0
XILIO THERAPEUTICS INC COM 98422T100 6,070 2,078,692 SH   DFND 1 2,078,692 0 0