The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
180 LIFE SCIENCES CORP COM 68236V104 2,603 3,915,000 SH   SOLE   3,915,000 0 0
2SEVENTY BIO INC COMMON STOCK 901384107 18,391 1,264,000 SH   SOLE   1,264,000 0 0
ACLARION INC *W EXP 04/21/202 655187110 209 550,000 SH   SOLE   550,000 0 0
ACURX PHARMACEUTICALS INC COM 00510M104 3,198 1,066,000 SH   SOLE   1,066,000 0 0
ADDEX THERAPEUTICS LTD SPONSORED ADS 00654J107 256 320,000 SH   SOLE   320,000 0 0
ADOBE SYSTEMS INCORPORATED COM 00724F101 50,637 184,000 SH   SOLE   184,000 0 0
ADVANCED MICRO DEVICES INC COM 007903107 7,603 120,000 SH   SOLE   120,000 0 0
ADVANTAGE SOLUTIONS INC COM CL A 00791N102 5,112 2,400,000 SH   SOLE   2,400,000 0 0
AGIOS PHARMACEUTICALS INC COM 00847X104 54,411 1,924,000 SH   SOLE   1,924,000 0 0
AGRIFORCE GROWING SYSTEMS LT *W EXP 02/01/202 C00948114 129 600,000 SH   SOLE   600,000 0 0
AINOS INC *W EXP 07/29/202 00902F113 19 25,000 SH   SOLE   25,000 0 0
AKARI THERAPEUTICS PLC SPONSORED ADR 00972G108 2,703 4,290,000 SH   SOLE   4,290,000 0 0
ALIBABA GROUP HLDG LTD SPONSORED ADS 01609W102 25,917 324,000 SH   SOLE   324,000 0 0
ALKERMES PLC SHS G01767105 84,675 3,792,000 SH   SOLE   3,792,000 0 0
ALPHABET INC CAP STK CL A 02079K305 44,764 468,000 SH   SOLE   468,000 0 0
ALPHATEC HLDGS INC COM NEW 02081G201 21,291 2,436,000 SH   SOLE   2,436,000 0 0
ALPINE 4 HOLDINGS INC CL A 02083E105 4,496 8,100,000 SH   SOLE   8,100,000 0 0
AMAZON COM INC COM 023135106 26,838 237,500 SH   SOLE   237,500 0 0
AMERICAN REBEL HOLDINGS INC *W EXP 01/20/202 02919L117 29 481,927 SH   SOLE   481,927 0 0
AMERICAN REBEL HOLDINGS INC COM 02919L208 222 671,000 SH   SOLE   671,000 0 0
AMRYT PHARMA PLC SPONSORED ADS 03217L106 8,802 1,272,000 SH   SOLE   1,272,000 0 0
ANHEUSER BUSCH INBEV SA/NV SPONSORED ADR 03524A108 51,844 1,148,000 SH   SOLE   1,148,000 0 0
APPTECH PMTS CORP *W EXP 01/04/202 03834B127 89 715,000 SH   SOLE   715,000 0 0
ARCADIA BIOSCIENCES INC COM NEW 039014204 850 1,609,850 SH   SOLE   1,609,850 0 0
ARGENX SE SPONSORED ADR 04016X101 42,366 120,000 SH   SOLE   120,000 0 0
ATERIAN INC COM 02156U101 8,013 6,462,000 SH   SOLE   6,462,000 0 0
AURINIA PHARMACEUTICALS INC COM 05156V102 5,444 724,000 SH   SOLE   724,000 0 0
AVALO THERAPEUTICS INC COM NEW 05338F207 13,163 3,964,666 SH   SOLE   3,964,666 0 0
AVINGER INC COM NEW 053734885 768 668,136 SH   SOLE   668,136 0 0
BATH & BODY WORKS INC COM 070830104 5,053 155,000 SH   SOLE   155,000 0 0
BENITEC BIOPHARMA INC COM 08205P100 578 1,555,039 SH   SOLE   1,555,039 0 0
BIOAFFINITY TECHNOLOGIES INC *W EXP 09/07/202 09076W117 72 204,082 SH   SOLE   204,082 0 0
BIOGEN INC COM 09062X103 59,808 224,000 SH   SOLE   224,000 0 0
BIOHAVEN LTD COM G1110E107 9,022 1,432,000 SH   SOLE   1,432,000 0 0
BIOLASE INC COM 090911405 1,699 699,000 SH   SOLE   699,000 0 0
BIOLINERX LTD SPONSORED ADS 09071M205 2,587 2,797,048 SH   SOLE   2,797,048 0 0
BIONTECH SE SPONSORED ADS 09075V102 21,041 156,000 SH   SOLE   156,000 0 0
BLUE WATER VACCINES INC COM 09610B108 1,468 858,360 SH   SOLE   858,360 0 0
BOOKING HOLDINGS INC COM 09857L108 6,080 3,700 SH   SOLE   3,700 0 0
BOXLIGHT CORP COM CL A 103197109 3,515 5,670,000 SH   SOLE   5,670,000 0 0
BRIACELL THERAPEUTICS CORP *W EXP 02/24/202 10778Y112 1,076 375,000 SH   SOLE   375,000 0 0
BRIGHT GREEN CORP COMMON STOCK 10920G100 5,143 4,761,905 SH   SOLE   4,761,905 0 0
BRISTOL-MYERS SQUIBB CO COM 110122108 42,654 600,000 SH   SOLE   600,000 0 0
BROOKLYN IMMUNOTHERAPEUTICS COM 114082100 274 1,109,807 SH   SOLE   1,109,807 0 0
BRUUSH ORAL CARE INC *W EXP 08/03/202 11750K120 163 600,962 SH   SOLE   600,962 0 0
CEA INDUSTRIES INC *W EXP 02/11/202 86887P119 105 700,000 SH   SOLE   700,000 0 0
CENTRAL GARDEN & PET CO CL A NON-VTG 153527205 52,948 1,550,000 SH   SOLE   1,550,000 0 0
CHIMERIX INC COM 16934W106 5,319 2,756,000 SH   SOLE   2,756,000 0 0
CINGULATE INC *W EXP 12/10/202 17248W113 90 410,000 SH   SOLE   410,000 0 0
CODIAK BIOSCIENCES INC COM 192010106 782 1,000,000 SH   SOLE   1,000,000 0 0
COLGATE PALMOLIVE CO COM 194162103 22,129 315,000 SH   SOLE   315,000 0 0
CONNEXA SPORTS TECHNOLOGIES COM NEW 831445200 346 1,018,510 SH   SOLE   1,018,510 0 0
COUPA SOFTWARE INC COM 22266L106 2,646 45,000 SH   SOLE   45,000 0 0
CRISPR THERAPEUTICS AG NAMEN AKT H17182108 60,383 924,000 SH   SOLE   924,000 0 0
CROCS INC COM 227046109 11,109 161,800 SH   SOLE   161,800 0 0
CROWDSTRIKE HLDGS INC CL A 22788C105 7,911 48,000 SH   SOLE   48,000 0 0
CUENTAS INC COM NEW 229794201 860 1,623,418 SH   SOLE   1,623,418 0 0
DATADOG INC CL A COM 23804L103 11,364 128,000 SH   SOLE   128,000 0 0
DECIPHERA PHARMACEUTICALS IN COM 24344T101 88,208 4,768,000 SH   SOLE   4,768,000 0 0
DECKERS OUTDOOR CORP COM 243537107 39,632 126,778 SH   SOLE   126,778 0 0
DERMATA THERAPEUTICS INC *W EXP 08/13/202 249845116 31 325,000 SH   SOLE   325,000 0 0
DIGITAL BRANDS GROUP INC *W EXP 05/01/202 25401N119 43 722,890 SH   SOLE   722,890 0 0
DIRECT DIGITAL HOLDINGS INC *W EXP 02/15/202 25461T113 243 900,000 SH   SOLE   900,000 0 0
DOLLAR TREE INC COM 256746108 18,446 135,535 SH   SOLE   135,535 0 0
EDIBLE GARDEN AG INC *W EXP 04/18/202 28059P113 81 800,000 SH   SOLE   800,000 0 0
ELASTIC N V ORD SHS N14506104 3,946 55,000 SH   SOLE   55,000 0 0
ELYS GAME TECHNOLOGY CORP COM 290734102 943 1,986,000 SH   SOLE   1,986,000 0 0
ENANTA PHARMACEUTICALS INC COM 29251M106 107,475 2,072,000 SH   SOLE   2,072,000 0 0
ENERGIZER HLDGS INC NEW COM 29272W109 39,017 1,552,000 SH   SOLE   1,552,000 0 0
ESPORTS ENTMT GROUP INC *W EXP 03/02/202 29667K132 189 2,700,000 SH   SOLE   2,700,000 0 0
EVERBRIDGE INC COM 29978A104 23,345 756,000 SH   SOLE   756,000 0 0
EXACT SCIENCES CORP COM 30063P105 50,684 1,560,000 SH   SOLE   1,560,000 0 0
FEDEX CORP COM 31428X106 11,878 80,000 SH   SOLE   80,000 0 0
FGI INDUSTRIES LTD *W EXP 01/21/202 G3302D111 375 933,333 SH   SOLE   933,333 0 0
FIBROGEN INC COM 31572Q808 57,973 4,456,000 SH   SOLE   4,456,000 0 0
FIVE BELOW INC COM 33829M101 76,163 553,231 SH   SOLE   553,231 0 0
FOOT LOCKER INC COM 344849104 32,430 1,041,769 SH   SOLE   1,041,769 0 0
FRESHPET INC COM 358039105 137,046 2,736,000 SH   SOLE   2,736,000 0 0
G MED INNOVATIONS HLDGS LTD *W EXP 06/30/202 G39462117 140 1,000,000 SH   SOLE   1,000,000 0 0
GOLD ROYALTY CORP *W EXP 99/99/999 38071H114 168 448,000 SH   SOLE   448,000 0 0
GREENLAND TECHNOLOGIES HLDG SHS NEW G4095T107 3,131 1,177,000 SH   SOLE   1,177,000 0 0
GROM SOCIAL ENTERPRISES INC *W EXP 06/17/202 39878L118 65 723,000 SH   SOLE   723,000 0 0
GSK PLC SPONSORED ADR 37733W204 105,948 3,600,000 SH   SOLE   3,600,000 0 0
HEALTHCARE TRIANGLE INC COM 42227W108 1,143 3,080,439 SH   SOLE   3,080,439 0 0
HEART TEST LABORATORIES INC *W EXP 06/15/202 42254E112 109 352,941 SH   SOLE   352,941 0 0
HEARTBEAM INC *W EXP 10/31/202 42238H116 295 500,000 SH   SOLE   500,000 0 0
I MAB SPONSORED ADS 44975P103 7,090 1,768,000 SH   SOLE   1,768,000 0 0
IMEDIA BRANDS INC COM CL A 452465206 488 762,000 SH   SOLE   762,000 0 0
IMMUNOCORE HLDGS PLC ADS 45258D105 14,833 316,000 SH   SOLE   316,000 0 0
INCYTE CORP COM 45337C102 157,670 2,366,000 SH   SOLE   2,366,000 0 0
INMED PHARMACEUTICALS INC COM NEW 457637601 593 90,000 SH   SOLE   90,000 0 0
INNOVATIVE EYEWEAR INC *W EXP 08/16/202 45791D117 84 210,000 SH   SOLE   210,000 0 0
INSULET CORP COM 45784P101 8,258 36,000 SH   SOLE   36,000 0 0
INTUIT COM 461202103 6,584 17,000 SH   SOLE   17,000 0 0
INTUITIVE SURGICAL INC COM NEW 46120E602 42,736 228,000 SH   SOLE   228,000 0 0
ISHARES TR RUSSELL 2000 ETF 464287655 593,712 3,600,000 SH Put SOLE   3,600,000 0 0
IVEDA SOLUTIONS INC *W EXP 04/01/202 46583A113 23 145,000 SH   SOLE   145,000 0 0
IVEDA SOLUTIONS INC COM NEW 46583A204 601 925,263 SH   SOLE   925,263 0 0
IVERIC BIO INC COM 46583P102 24,470 1,364,000 SH   SOLE   1,364,000 0 0
JEFFS BRANDS LTD *W EXP 08/26/202 M61472110 80 480,769 SH   SOLE   480,769 0 0
JOHNSON & JOHNSON COM 478160104 13,069 80,000 SH   SOLE   80,000 0 0
KALERA PUBLIC LIMITED CO ORDINARY SHARES G52251108 2,446 1,839,347 SH   SOLE   1,839,347 0 0
KRAFT HEINZ CO COM 500754106 55,028 1,650,000 SH   SOLE   1,650,000 0 0
LAUDER ESTEE COS INC CL A 518439104 16,840 78,000 SH   SOLE   78,000 0 0
LOCAFY LIMITED *W EXP 03/29/202 Q56120118 40 242,425 SH   SOLE   242,425 0 0
LOWES COS INC COM 548661107 62,566 333,132 SH   SOLE   333,132 0 0
LULULEMON ATHLETICA INC COM 550021109 73,098 261,475 SH   SOLE   261,475 0 0
MACROGENICS INC COM 556099109 21,203 6,128,000 SH   SOLE   6,128,000 0 0
MADRIGAL PHARMACEUTICALS INC COM 558868105 80,328 1,236,000 SH   SOLE   1,236,000 0 0
MARIS TECH LTD *W EXP 02/04/202 M68057112 211 1,261,058 SH   SOLE   1,261,058 0 0
MAWSON INFRASTRUCTURE GROUP COM NEW 57778N208 1,697 3,933,407 SH   SOLE   3,933,407 0 0
MEDIGUS LTD *W EXP 07/23/202 58471G128 129 1,285,715 SH   SOLE   1,285,715 0 0
MEDIWOUND LTD ORD SHS M68830104 2,663 1,915,520 SH   SOLE   1,915,520 0 0
MEDTRONIC PLC SHS G5960L103 58,463 724,000 SH   SOLE   724,000 0 0
META PLATFORMS INC CL A 30303M102 8,276 61,000 SH   SOLE   61,000 0 0
MICROSOFT CORP COM 594918104 37,497 161,000 SH   SOLE   161,000 0 0
MIRATI THERAPEUTICS INC COM 60468T105 132,696 1,900,000 SH   SOLE   1,900,000 0 0
MOBILE GLOBAL ESPORTS INC COM 607371101 3,585 1,886,793 SH   SOLE   1,886,793 0 0
MOBILICOM LTD *W EXP 08/31/202 60742B110 92 242,100 SH   SOLE   242,100 0 0
MONDAY COM LTD SHS M7S64H106 3,400 30,000 SH   SOLE   30,000 0 0
MONDELEZ INTL INC CL A 609207105 31,308 571,000 SH   SOLE   571,000 0 0
MONGODB INC CL A 60937P106 5,361 27,000 SH   SOLE   27,000 0 0
NATERA INC COM 632307104 29,447 672,000 SH   SOLE   672,000 0 0
NETFLIX INC COM 64110L106 5,297 22,500 SH   SOLE   22,500 0 0
NEUROCRINE BIOSCIENCES INC COM 64125C109 140,622 1,324,000 SH   SOLE   1,324,000 0 0
NEXALIN TECHNOLOGY INC *W EXP 09/15/202 65345B110 58 325,000 SH   SOLE   325,000 0 0
NEXGEL INC *W EXP 12/01/202 65344E115 165 550,000 SH   SOLE   550,000 0 0
NLS PHARMACEUTICS LTD *W EXP 09/25/202 H57830111 125 500,000 SH   SOLE   500,000 0 0
NOVAN INC COM NEW 66988N205 4,288 2,293,000 SH   SOLE   2,293,000 0 0
NUVVE HOLDING CORP COM 67079Y100 2,269 1,620,552 SH   SOLE   1,620,552 0 0
ONFOLIO HOLDINGS INC *W EXP 01/02/202 68277K124 74 400,000 SH   SOLE   400,000 0 0
OPGEN INC COM 68373L307 1,517 5,300,000 SH   SOLE   5,300,000 0 0
OREILLY AUTOMOTIVE INC COM 67103H107 70,519 100,261 SH   SOLE   100,261 0 0
ORGANON & CO COMMON STOCK 68622V106 39,593 1,692,000 SH   SOLE   1,692,000 0 0
PACIRA BIOSCIENCES INC COM 695127100 84,678 1,592,000 SH   SOLE   1,592,000 0 0
PALO ALTO NETWORKS INC COM 697435105 12,579 76,800 SH   SOLE   76,800 0 0
PANBELA THERAPEUTICS INC COM 69833W107 588 2,176,809 SH   SOLE   2,176,809 0 0
PARAMOUNT GLOBAL CLASS B COM 92556H206 30,464 1,600,000 SH   SOLE   1,600,000 0 0
PASITHEA THERAPEUTICS CORP *W EXP 08/12/202 70261F111 148 1,000,000 SH   SOLE   1,000,000 0 0
PETVIVO HLDGS INC *W EXP 08/13/202 716817119 87 200,000 SH   SOLE   200,000 0 0
PFIZER INC COM 717081103 23,455 536,000 SH   SOLE   536,000 0 0
POST HLDGS INC COM 737446104 26,539 324,000 SH   SOLE   324,000 0 0
PTC THERAPEUTICS INC COM 69366J200 145,580 2,900,000 SH   SOLE   2,900,000 0 0
PUMA BIOTECHNOLOGY INC COM 74587V107 2,370 1,000,000 SH   SOLE   1,000,000 0 0
RAIL VISION LTD *W EXP 03/27/202 M8186D114 90 1,089,500 SH   SOLE   1,089,500 0 0
REGENERON PHARMACEUTICALS COM 75886F107 93,686 136,000 SH   SOLE   136,000 0 0
RIGEL PHARMACEUTICALS INC COM NEW 766559603 4,074 3,452,874 SH   SOLE   3,452,874 0 0
ROCKWELL MED INC COM NEW 774374300 1,266 959,000 SH   SOLE   959,000 0 0
ROSS STORES INC COM 778296103 97,595 1,158,117 SH   SOLE   1,158,117 0 0
SAVERONE 2014 LTD *W EXP 06/02/202 80516T113 73 242,100 SH   SOLE   242,100 0 0
SCPHARMACEUTICALS INC COM 810648105 16,248 2,492,000 SH   SOLE   2,492,000 0 0
SENTINELONE INC CL A 81730H109 3,067 120,000 SH   SOLE   120,000 0 0
SEQLL INC *W EXP 08/31/202 81734C114 4 50,000 SH   SOLE   50,000 0 0
SERVICENOW INC COM 81762P102 6,419 17,000 SH   SOLE   17,000 0 0
SHARPS TECHNOLOGY INC *W EXP 04/13/202 82003F119 413 1,176,000 SH   SOLE   1,176,000 0 0
SHIFTPIXY INC COM NEW 82452L302 5,750 416,667 SH   SOLE   416,667 0 0
SHOCKWAVE MED INC COM 82489T104 10,011 36,000 SH   SOLE   36,000 0 0
SHOPIFY INC CL A 82509L107 16,838 625,000 SH   SOLE   625,000 0 0
SKECHERS U S A INC CL A 830566105 4,651 146,616 SH   SOLE   146,616 0 0
SNAP INC CL A 83304A106 3,437 350,000 SH   SOLE   350,000 0 0
SOBR SAFE INC COM NEW 833592207 3,350 1,250,000 SH   SOLE   1,250,000 0 0
SPDR S&P 500 ETF TR TR UNIT 78462F103 1,196,553 3,350,000 SH Put SOLE   3,350,000 0 0
SPECTRUM PHARMACEUTICALS INC COM 84763A108 7,171 16,676,000 SH   SOLE   16,676,000 0 0
SPLASH BEVERAGE GROUP INC *W EXP 06/15/202 84862C112 371 904,000 SH   SOLE   904,000 0 0
STEAKHOLDER FOODS LTD SPONSORED ADS 583435102 967 496,000 SH   SOLE   496,000 0 0
STRAN & COMPANY INC *W EXP 11/01/202 86260J110 142 545,000 SH   SOLE   545,000 0 0
STRONGHOLD DIGITAL MINING IN CLASS A COM 86337R103 2,365 2,274,350 SH   SOLE   2,274,350 0 0
STRYVE FOODS INC CLASS A COM 863685103 352 663,901 SH   SOLE   663,901 0 0
SUPERNUS PHARMACEUTICALS INC COM 868459108 155,473 4,593,004 SH   SOLE   4,593,004 0 0
SWVL HOLDINGS CORP CLASS A COM G86302109 6,985 8,304,000 SH   SOLE   8,304,000 0 0
T STAMP INC CL A NEW 873048300 963 975,000 SH   SOLE   975,000 0 0
TAKE-TWO INTERACTIVE SOFTWAR COM 874054109 2,398 22,000 SH   SOLE   22,000 0 0
TARGET CORP COM 87612E106 44,664 300,989 SH   SOLE   300,989 0 0
TARO PHARMACEUTICAL INDS LTD SHS M8737E108 7,356 245,372 SH   SOLE   245,372 0 0
TC BIOPHARM HOLDINGS PLC *W EXP 02/08/202 87807D111 435 1,882,352 SH   SOLE   1,882,352 0 0
TENAX THERAPEUTICS INC COM NEW 88032L209 334 1,965,885 SH   SOLE   1,965,885 0 0
TERNS PHARMACEUTICALS INC COM 880881107 3,534 600,000 SH   SOLE   600,000 0 0
THE VERY GOOD FOOD CO INC COM 88340B109 1,607 13,100,000 SH   SOLE   13,100,000 0 0
THERMO FISHER SCIENTIFIC INC COM 883556102 25,360 50,000 SH   SOLE   50,000 0 0
TOAST INC CL A 888787108 19,462 1,164,000 SH   SOLE   1,164,000 0 0
TRAVERE THERAPEUTICS INC COM 89422G107 143,799 5,836,000 SH   SOLE   5,836,000 0 0
TREVI THERAPEUTICS INC COM 89532M101 1,331 864,000 SH   SOLE   864,000 0 0
TWILIO INC CL A 90138F102 2,766 40,000 SH   SOLE   40,000 0 0
UBER TECHNOLOGIES INC COM 90353T100 22,154 836,000 SH   SOLE   836,000 0 0
UNITEDHEALTH GROUP INC COM 91324P102 12,121 24,000 SH   SOLE   24,000 0 0
UPHEALTH INC *W EXP 06/08/202 91532B119 1 10,000 SH   SOLE   10,000 0 0
VERASTEM INC COM 92337C104 1,700 2,000,000 SH   SOLE   2,000,000 0 0
VERTEX PHARMACEUTICALS INC COM 92532F100 43,431 150,000 SH   SOLE   150,000 0 0
VIQ SOLUTIONS INC COM NEW 91825V400 800 1,290,663 SH   SOLE   1,290,663 0 0
VIVOPOWER INTERNATIONAL PLC SHS G9376R100 1,017 1,421,759 SH   SOLE   1,421,759 0 0
VOYAGER THERAPEUTICS INC COM 92915B106 20,104 3,396,000 SH   SOLE   3,396,000 0 0
WHOLE EARTH BRANDS INC COM CL A 96684W100 9,200 2,395,802 SH   SOLE   2,395,802 0 0
WORKDAY INC CL A 98138H101 5,328 35,000 SH   SOLE   35,000 0 0
XERIS BIOPHARMA HOLDINGS INC COM 98422E103 3,907 2,504,431 SH   SOLE   2,504,431 0 0
ZIMVIE INC COM 98888T107 6,416 650,000 SH   SOLE   650,000 0 0
ZOOMINFO TECHNOLOGIES INC COMMON STOCK 98980F104 3,916 94,000 SH   SOLE   94,000 0 0
ZYMEWORKS INC COM 98985W102 35,578 5,785,000 SH   SOLE   5,785,000 0 0