The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete. | |||||||||||||||||
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UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 13F FORM 13F INFORMATION TABLE |
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| COLUMN 1 | COLUMN 2 | COLUMN 3 | COLUMN 4 | COLUMN 5 | COLUMN 6 | COLUMN 7 | COLUMN 8 | ||||
| VALUE | SHRS OR | SH/ | PUT/ | INVESTMENT | OTHER | VOTING AUTHORITY | |||||
| NAME OF ISSUER | TITLE OF CLASS | CUSIP | (x$1000) | PRN AMT | PRN | CALL | DISCRETION | MANAGER | SOLE | SHARED | NONE |
| ADICET BIO INC | COM | 007002108 | 30,017 | 2,115,385 | SH | DFND | 1 | 0 | 2,115,385 | 0 | |
| AEGLEA BIOTHERAPEUTICS INC | COM | 00773J103 | 127 | 240,500 | SH | DFND | 1 | 0 | 240,500 | 0 | |
| CYMABAY THERAPEUTICS INC | COM | 23257D103 | 457 | 131,036 | SH | DFND | 1 | 0 | 131,036 | 0 | |
| EFFECTOR THERAPEUTICS INC | COM | 28202V108 | 2,730 | 4,822,114 | SH | DFND | 1 | 0 | 4,822,114 | 0 | |
| EXICURE INC | COM NEW | 30205M200 | 439 | 281,636 | SH | DFND | 1 | 0 | 281,636 | 0 | |
| HILLEVAX INC | COM | 43157M102 | 31,401 | 1,838,486 | SH | DFND | 1 | 0 | 1,838,486 | 0 | |
| JASPER THERAPEUTICS INC | COM | 471871103 | 4,441 | 5,628,558 | SH | DFND | 1 | 0 | 5,628,558 | 0 | |
| MOLECULAR TEMPLATES INC | COM | 608550109 | 150 | 200,000 | SH | DFND | 1 | 0 | 200,000 | 0 | |
| NUCANA PLC | SPONSORED ADR | 67022C106 | 3,400 | 3,333,333 | SH | DFND | 1 | 0 | 3,333,333 | 0 | |
| OBSEVA SA | COM | H5861P103 | 13 | 87,999 | SH | DFND | 1 | 0 | 87,999 | 0 | |
| PARATEK PHARMACEUTICALS INC | COM | 699374302 | 2,676 | 1,041,131 | SH | DFND | 1 | 0 | 1,041,131 | 0 | |
| PHATHOM PHARMACEUTICALS INC | COM | 71722W107 | 15,901 | 1,435,106 | SH | DFND | 1 | 0 | 1,435,106 | 0 | |
| RENEO PHARMACEUTICALS INC | COM | 75974E103 | 6,948 | 2,073,957 | SH | DFND | 1 | 0 | 2,073,957 | 0 | |
| SIENTRA INC | COM | 82621J105 | 1,071 | 1,673,589 | SH | DFND | 1 | 0 | 1,673,589 | 0 | |
| SOLENO THERAPEUTICS INC | COM | 834203309 | 2,007 | 1,201,506 | SH | DFND | 1 | 0 | 1,201,506 | 0 | |
| SPRUCE BIOSCIENCES INC | COM | 85209E109 | 2,474 | 1,792,518 | SH | DFND | 1 | 0 | 1,792,518 | 0 | |
| VAXCYTE INC | COM | 92243G108 | 100,049 | 4,168,718 | SH | DFND | 1 | 0 | 4,168,718 | 0 | |
| VERA THERAPEUTICS INC | CL A | 92337R101 | 63,083 | 2,960,231 | SH | DFND | 1 | 0 | 2,960,231 | 0 | |
| VERONA PHARMA PLC | SPONSORED ADS | 925050106 | 25,091 | 2,457,500 | SH | DFND | 1 | 0 | 2,457,500 | 0 | |