The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ABCAM PLC ADS 000380204 30,467 2,032,500 SH   SOLE   2,032,500 0 0
ACADIA HEALTHCARE COMPANY IN COM 00404A109 66,062 845,000 SH   SOLE   845,000 0 0
ACCOLADE INC COM 00437E102 25,969 2,274,000 SH   SOLE   2,274,000 0 0
ACELRX PHARMACEUTICALS INC COM 00444T100 1,323 6,329,202 SH   SOLE   6,329,202 0 0
ACLARIS THERAPEUTICS INC COM 00461U105 62,350 3,961,249 SH   SOLE   3,961,249 0 0
ADAPTIMMUNE THERAPEUTICS PLC SPONDS ADR 00653A107 2,534 2,357,544 SH   SOLE   2,357,544 0 0
AEGLEA BIOTHERAPEUTICS INC COM 00773J103 1,796 3,413,906 SH   SOLE   3,413,906 0 0
AGILON HEALTH INC COM 00857U107 181,446 7,747,500 SH   SOLE   7,747,500 0 0
AGIOS PHARMACEUTICALS INC COM 00847X104 86,477 3,057,869 SH   SOLE   3,057,869 0 0
AKERO THERAPEUTICS INC COM 00973Y108 46,648 1,369,973 SH   SOLE   1,369,973 0 0
ALIGN TECHNOLOGY INC COM 016255101 71,246 344,000 SH   SOLE   344,000 0 0
ALNYLAM PHARMACEUTICALS INC COM 02043Q107 66,553 332,500 SH   SOLE   332,500 0 0
ALTIMMUNE INC COM NEW 02155H200 2,851 223,255 SH   SOLE   223,255 0 0
ALTIMMUNE INC COM NEW 02155H200 428 33,500 SH Call SOLE   33,500 0 0
AMICUS THERAPEUTICS INC COM 03152W109 10,571 1,012,506 SH   SOLE   1,012,506 0 0
AMRYT PHARMA PLC SPONSORED ADS 03217L106 9,173 1,325,625 SH   SOLE   1,325,625 0 0
AMYLYX PHARMACEUTICALS INC COM 03237H101 11,365 403,737 SH   SOLE   403,737 0 0
ANAPTYSBIO INC COM 032724106 14,709 576,600 SH   SOLE   576,600 0 0
APPLIED THERAPEUTICS INC COM 03828A101 653 701,680 SH   SOLE   701,680 0 0
ARGENX SE SPONSORED ADR 04016X101 123,568 350,000 SH   SOLE   350,000 0 0
ARVINAS INC COM 04335A105 12,462 280,100 SH   SOLE   280,100 0 0
ASCENDIS PHARMA A/S SPONSORED ADR 04351P101 43,937 425,500 SH   SOLE   425,500 0 0
ATRECA INC CL A COM 04965G109 726 462,530 SH   SOLE   462,530 0 0
AURA BIOSCIENCES INC COM 05153U107 18,406 1,015,757 SH   SOLE   1,015,757 0 0
AURINIA PHARMACEUTICALS INC COM 05156V102 8,019 1,066,408 SH   SOLE   1,066,408 0 0
AZENTA INC COM 114340102 14,152 330,200 SH   SOLE   330,200 0 0
BAXTER INTL INC COM 071813109 40,691 755,500 SH   SOLE   755,500 0 0
BCLS ACQUISITION CORP COM CL A G0904B105 3,096 309,000 SH   SOLE   309,000 0 0
BEAM THERAPEUTICS INC COM 07373V105 5,309 111,430 SH   SOLE   111,430 0 0
BIOCRYST PHARMACEUTICALS INC COM 09058V103 21,578 1,712,507 SH   SOLE   1,712,507 0 0
BIOHAVEN LTD COM G1110E107 1,055 167,421 SH   SOLE   167,421 0 0
BIOMARIN PHARMACEUTICAL INC COM 09061G101 22,422 264,500 SH   SOLE   264,500 0 0
BIOMEA FUSION INC COM 09077A106 7,148 730,846 SH   SOLE   730,846 0 0
BLUEPRINT MEDICINES CORP COM 09627Y109 101,352 1,538,195 SH   SOLE   1,538,195 0 0
CELLDEX THERAPEUTICS INC NEW COM NEW 15117B202 11,851 421,604 SH   SOLE   421,604 0 0
CEREVEL THERAPEUTICS HLDNG I COM 15678U128 70,626 2,499,148 SH   SOLE   2,499,148 0 0
CHINOOK THERAPEUTICS INC COM 16961L106 9,978 507,512 SH   SOLE   507,512 0 0
CINCOR PHARMA INC COM 17240Y109 39,576 1,205,856 SH   SOLE   1,205,856 0 0
COLLEGIUM PHARMACEUTICAL INC COM 19459J104 11,615 725,000 SH   SOLE   725,000 0 0
COMPASS THERAPEUTICS INC COM 20454B104 12,160 5,333,188 SH   SOLE   5,333,188 0 0
COMPUGEN LTD ORD M25722105 848 1,289,990 SH   SOLE   1,289,990 0 0
CONMED CORP COM 207410101 18,680 233,000 SH   SOLE   233,000 0 0
COVETRUS INC COM 22304C100 35,053 1,678,800 SH   SOLE   1,678,800 0 0
CYTOKINETICS INC COM NEW 23282W605 21,463 443,000 SH   SOLE   443,000 0 0
DESIGN THERAPEUTICS INC COM 25056L103 7,698 460,391 SH   SOLE   460,391 0 0
DEXCOM INC COM 252131107 39,505 490,500 SH   SOLE   490,500 0 0
DYNAVAX TECHNOLOGIES CORP COM NEW 268158201 17,574 1,683,358 SH   SOLE   1,683,358 0 0
EDAP TMS S A SPONSORED ADR 268311107 7,508 910,000 SH   SOLE   910,000 0 0
EDWARDS LIFESCIENCES CORP COM 28176E108 52,140 631,000 SH   SOLE   631,000 0 0
EQRX INC COM 26886C107 4,950 1,000,000 SH   SOLE   1,000,000 0 0
ESSA PHARMA INC COM NEW 29668H708 955 524,944 SH   SOLE   524,944 0 0
EVOLENT HEALTH INC CL A 30050B101 117,222 3,262,500 SH   SOLE   3,262,500 0 0
EXACT SCIENCES CORP COM 30063P105 18,799 578,600 SH   SOLE   578,600 0 0
FATE THERAPEUTICS INC COM 31189P102 2,465 110,000 SH   SOLE   110,000 0 0
FRESHPET INC COM 358039105 35,063 700,000 SH   SOLE   700,000 0 0
F-STAR THERAPEUTICS INC COM 30315R107 3,850 751,889 SH   SOLE   751,889 0 0
FULCRUM THERAPEUTICS INC COM 359616109 3,111 384,590 SH   SOLE   384,590 0 0
GAMIDA CELL LTD SHS M47364100 6,551 4,119,883 SH   SOLE   4,119,883 0 0
GOSSAMER BIO INC COM 38341P102 19,012 1,586,962 SH   SOLE   1,586,962 0 0
GOSSAMER BIO INC NOTE 5.000% 6/0 38341PAA0 9,884 9,573,000 PRN   SOLE   9,573,000 0 0
GUARDANT HEALTH INC COM 40131M109 10,766 200,000 SH   SOLE   200,000 0 0
HEALTH CATALYST INC COM 42225T107 8,536 880,000 SH   SOLE   880,000 0 0
HORIZON THERAPEUTICS PUB L SHS G46188101 44,994 727,000 SH   SOLE   727,000 0 0
HUMANA INC COM 444859102 206,934 426,500 SH   SOLE   426,500 0 0
ICOSAVAX INC COM 45114M109 2,468 781,000 SH   SOLE   781,000 0 0
IDEXX LABS INC COM 45168D104 73,082 224,315 SH   SOLE   224,315 0 0
IMARA INC COM 45249V107 1,921 842,402 SH   SOLE   842,402 0 0
IMMATICS N.V SHS N44445109 16,812 1,681,224 SH   SOLE   1,681,224 0 0
IMMUNOCORE HLDGS PLC ADS 45258D105 163,996 3,493,743 SH   SOLE   3,493,743 0 0
INOZYME PHARMA INC COM 45790W108 7,524 2,807,618 SH   SOLE   2,807,618 0 0
INSULET CORP COM 45784P101 118,944 518,500 SH   SOLE   518,500 0 0
INTUITIVE SURGICAL INC COM NEW 46120E602 55,951 298,500 SH   SOLE   298,500 0 0
INVITAE CORP COM 46185L103 8,332 3,386,855 SH   SOLE   3,386,855 0 0
IRHYTHM TECHNOLOGIES INC COM 450056106 36,738 293,250 SH   SOLE   293,250 0 0
JIYA ACQUISITION CORP COM CL A 47760M102 2,056 206,200 SH   SOLE   206,200 0 0
KARUNA THERAPEUTICS INC COM 48576A100 93,067 413,762 SH   SOLE   413,762 0 0
KINNATE BIOPHARMA INC COM 49705R105 8,926 746,973 SH   SOLE   746,973 0 0
KYMERA THERAPEUTICS INC COM 501575104 22,788 1,046,743 SH   SOLE   1,046,743 0 0
LEAP THERAPEUTICS INC COM 52187K101 3,221 3,659,847 SH   SOLE   3,659,847 0 0
LEGEND BIOTECH CORP SPONSORED ADS 52490G102 18,379 450,466 SH   SOLE   450,466 0 0
LIFESTANCE HEALTH GROUP INC COM 53228F101 13,240 2,000,000 SH   SOLE   2,000,000 0 0
MACROGENICS INC COM 556099109 4,175 1,206,642 SH   SOLE   1,206,642 0 0
MADRIGAL PHARMACEUTICALS INC COM 558868105 20,633 317,485 SH   SOLE   317,485 0 0
MEREO BIOPHARMA GROUP PLC SPON ADS 589492107 5,377 6,244,897 SH   SOLE   6,244,897 0 0
MERSANA THERAPEUTICS INC COM 59045L106 27,553 4,075,958 SH   SOLE   4,075,958 0 0
MIRATI THERAPEUTICS INC COM 60468T105 60,536 866,776 SH   SOLE   866,776 0 0
MIRUM PHARMACEUTICALS INC COM 604749101 37,728 1,795,733 SH   SOLE   1,795,733 0 0
NEUROCRINE BIOSCIENCES INC COM 64125C109 119,221 1,122,500 SH   SOLE   1,122,500 0 0
NEUROCRINE BIOSCIENCES INC NOTE 2.250% 5/1 64125CAD1 1,413 1,000,000 PRN   SOLE   1,000,000 0 0
NEVRO CORP NOTE 2.750% 4/0 64157FAC7 473 500,000 PRN   SOLE   500,000 0 0
NEVRO CORP COM 64157F103 36,674 787,000 SH   SOLE   787,000 0 0
NKARTA INC COM 65487U108 8,110 616,277 SH   SOLE   616,277 0 0
NOVAVAX INC COM NEW 670002401 10,907 599,300 SH   SOLE   599,300 0 0
NOVOCURE LTD ORD SHS G6674U108 13,297 175,000 SH   SOLE   175,000 0 0
NUVATION BIO INC *W EXP 07/07/202 67080N119 27 134,028 SH   SOLE   134,028 0 0
OLINK HLDG AB SPONSORED ADS 680710100 17,542 1,445,000 SH   SOLE   1,445,000 0 0
ORION ACQUISITION CORP UNIT 02/19/2026 68626A207 9,870 1,000,000 SH   SOLE   1,000,000 0 0
PACIRA BIOSCIENCES INC COM 695127100 54,121 1,017,500 SH   SOLE   1,017,500 0 0
PARATEK PHARMACEUTICALS INC COM 699374302 4,456 1,734,037 SH   SOLE   1,734,037 0 0
PENUMBRA INC COM 70975L107 90,250 476,000 SH   SOLE   476,000 0 0
PHASEBIO PHARMACEUTICALS INC COM 717224109 479 2,719,074 SH   SOLE   2,719,074 0 0
PHREESIA INC COM 71944F106 33,188 1,302,500 SH   SOLE   1,302,500 0 0
PROMETHEUS BIOSCIENCES INC COM 74349U108 38,085 645,407 SH   SOLE   645,407 0 0
PROTHENA CORP PLC SHS G72800108 41,135 678,462 SH   SOLE   678,462 0 0
PULMONX CORP COM 745848101 9,953 597,400 SH   SOLE   597,400 0 0
RELAY THERAPEUTICS INC COM 75943R102 13,831 618,267 SH   SOLE   618,267 0 0
RENEO PHARMACEUTICALS INC COM 75974E103 3,830 1,143,185 SH   SOLE   1,143,185 0 0
RHYTHM PHARMACEUTICALS INC COM 76243J105 43,141 1,760,865 SH   SOLE   1,760,865 0 0
SAREPTA THERAPEUTICS INC COM 803607100 47,532 430,000 SH   SOLE   430,000 0 0
SEAGEN INC COM 81181C104 37,218 272,000 SH   SOLE   272,000 0 0
SELECT SECTOR SPDR TR SBI HEALTHCARE 81369Y209 24,222 200,000 SH   SOLE   200,000 0 0
SHOCKWAVE MED INC COM 82489T104 50,080 180,100 SH   SOLE   180,100 0 0
SPERO THERAPEUTICS INC COM 84833T103 1,541 770,710 SH   SOLE   770,710 0 0
SPRUCE BIOSCIENCES INC COM 85209E109 2,223 1,622,689 SH   SOLE   1,622,689 0 0
TEMPEST THERAPEUTICS INC COM 87978U108 1,433 823,654 SH   SOLE   823,654 0 0
THESEUS PHARMACEUTICALS INC COM 88369M101 2,537 437,329 SH   SOLE   437,329 0 0
TRAVERE THERAPEUTICS INC NOTE 2.500% 9/1 761299AB2 3,289 3,250,000 PRN   SOLE   3,250,000 0 0
TRAVERE THERAPEUTICS INC COM 89422G107 23,449 951,650 SH   SOLE   951,650 0 0
ULTRAGENYX PHARMACEUTICAL IN COM 90400D108 49,195 1,187,992 SH   SOLE   1,187,992 0 0
UNITEDHEALTH GROUP INC COM 91324P102 136,108 269,500 SH   SOLE   269,500 0 0
VERVE THERAPEUTICS INC COM 92539P101 19,196 558,837 SH   SOLE   558,837 0 0
VIGIL NEUROSCIENCE INC COM 92673K108 4,295 471,958 SH   SOLE   471,958 0 0
VINCERX PHARMA INC COM NEW 92731L106 1,530 1,108,570 SH   SOLE   1,108,570 0 0
WARBY PARKER INC CL A COM 93403J106 17,468 1,309,475 SH   SOLE   1,309,475 0 0
WEST PHARMACEUTICAL SVSC INC COM 955306105 44,417 180,500 SH   SOLE   180,500 0 0
XENON PHARMACEUTICALS INC COM 98420N105 41,730 1,155,961 SH   SOLE   1,155,961 0 0
XILIO THERAPEUTICS INC COM 98422T100 3,966 1,362,878 SH   SOLE   1,362,878 0 0
ZAI LAB LTD ADR 98887Q104 40,780 1,192,400 SH   SOLE   1,192,400 0 0