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The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP FIGI (to the nearest dollar) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
AADI BIOSCIENCES INC Common 00032Q104   36,557,828 2,849,402 SH   SOLE   2,849,402 0 0
ALNYLAM PHARMACEUTICALS INC Common 02043Q107   262,603,250 1,105,000 SH   SOLE   1,105,000 0 0
AMICUS THERAPEUTICS INC Common 03152W109   327,228,000 26,800,000 SH   SOLE   26,800,000 0 0
AMYLYX PHARMACEUTICALS INC Common 03237H101   23,278,500 630,000 SH   SOLE   630,000 0 0
APELLIS PHARMACEUTICALS INC Common 03753U106   549,418,750 10,625,000 SH   SOLE   10,625,000 0 0
ARGENX SE Sponsored ADR 04016X101   479,430,201 1,265,555 SH   SOLE   1,265,555 0 0
ASCENDIS PHARMA Sponsored ADR 04351P101   378,603,000 3,100,000 SH   SOLE   3,100,000 0 0
AVIDITY BIOSCIENCES INC Common 05370A108   45,489,500 2,050,000 SH   SOLE   2,050,000 0 0
BIOCRYST PHARMACEUTICALS INC Common 09058V103   103,894,000 9,050,000 SH   SOLE   9,050,000 0 0
BIOMARIN PHARMACEUTICAL INC Common 09061G101   367,964,387 3,555,555 SH   SOLE   3,555,555 0 0
CYMABAY THERAPEUTICS INC Common 23257D103   64,581,000 10,300,000 SH   SOLE   10,300,000 0 0
DESIGN THERAPEUTICS INC Common 25056L103   23,312,998 2,272,222 SH   SOLE   2,272,222 0 0
DICE THERAPEUTICS INC Common 23345J104   78,797,316 2,525,555 SH   SOLE   2,525,555 0 0
FENNEC PHARMACEUTICALS INC Common 31447P100   11,520,000 1,200,000 SH   SOLE   1,200,000 0 0
HORIZON THERAPEUTICS PLC Common G46188101   796,600,000 7,000,000 SH   SOLE   7,000,000 0 0
IO BIOTECH INC Common 449778109   4,728,531 2,055,883 SH   SOLE   2,055,883 0 0
IOVANCE BIOTHERAPEUTICS INC Common 462260100   44,857,800 7,020,000 SH   SOLE   7,020,000 0 0
IVERIC BIO INC Common 46583P102   144,517,500 6,750,000 SH   SOLE   6,750,000 0 0
KRYSTAL BIOTECH INC Common 501147102   111,700,200 1,410,000 SH   SOLE   1,410,000 0 0
KURA ONCOLOGY INC Common 50127T109   38,533,050 3,105,000 SH   SOLE   3,105,000 0 0
KYMERA THERAPEUTICS INC Common 501575104   96,096,000 3,850,000 SH   SOLE   3,850,000 0 0
MADRIGAL PHARMACEUTICALS INC Common 558868105   481,815,000 1,660,000 SH   SOLE   1,660,000 0 0
MANNKIND CORP Common 56400P706   47,957,000 9,100,000 SH   SOLE   9,100,000 0 0
MARINUS PHARMACEUTICALS INC Common 56854Q200   12,537,000 3,150,000 SH   SOLE   3,150,000 0 0
MERSANA THERAPEUTICS INC Common 59045L106   44,243,000 7,550,000 SH   SOLE   7,550,000 0 0
MIRATI THERAPEUTICS INC Common 60468T105   251,722,197 5,555,555 SH   SOLE   5,555,555 0 0
MONTE ROSA THERAPEUTICS INC Common 61225M102   32,913,250 4,325,000 SH   SOLE   4,325,000 0 0
NUVALENT INC Common 670703107   46,324,428 1,555,555 SH   SOLE   1,555,555 0 0
PMV PHARMACEUTICALS INC Common 69353Y103   26,622,000 3,060,000 SH   SOLE   3,060,000 0 0
SAREPTA THERAPEUTICS INC Common 803607100   411,416,500 3,175,000 SH   SOLE   3,175,000 0 0
SEAGEN INC Common 81181C104   242,241,350 1,885,000 SH   SOLE   1,885,000 0 0
SYNDAX PHARMACEUTICALS INC Common 87164F105   67,442,500 2,650,000 SH   SOLE   2,650,000 0 0
TANGO THERAPEUTICS INC Common 87583X109   11,890,000 1,640,000 SH   SOLE   1,640,000 0 0
ULTRAGENYX PHARMACEUTICAL INC Common 90400D108   34,747,500 750,000 SH   SOLE   750,000 0 0
UNITED THERAPEUTICS CORP Common 91307C102   796,727,850 2,865,000 SH   SOLE   2,865,000 0 0
XENON PHARMACEUTICALS INC Common 98420N105   193,207,000 4,900,000 SH   SOLE   4,900,000 0 0