The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete. | |||||||||||||||||
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UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 13F FORM 13F INFORMATION TABLE |
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| COLUMN 1 | COLUMN 2 | COLUMN 3 | COLUMN 4 | COLUMN 5 | COLUMN 6 | COLUMN 7 | COLUMN 8 | |||||
| VALUE | SHRS OR | SH/ | PUT/ | INVESTMENT | OTHER | VOTING AUTHORITY | ||||||
| NAME OF ISSUER | TITLE OF CLASS | CUSIP | FIGI | (to the nearest dollar) | PRN AMT | PRN | CALL | DISCRETION | MANAGER | SOLE | SHARED | NONE |
| 2SEVENTY BIO INC | COMMON STOCK | 901384107 | 2,342,500 | 250,000 | SH | OTR | 1 | 0 | 250,000 | 0 | ||
| ACELRX PHARMACEUTICALS INC | COM NEW | 00444T209 | 440,700 | 195,000 | SH | OTR | 1 | 0 | 195,000 | 0 | ||
| ADICET BIO INC | COM | 007002108 | 5,364,000 | 600,000 | SH | OTR | 1 | 0 | 600,000 | 0 | ||
| ALBIREO PHARMA INC | COM | 01345P106 | 8,902,628 | 411,968 | SH | OTR | 1 | 0 | 411,968 | 0 | ||
| ALDEYRA THERAPEUTICS INC | COM | 01438T106 | 1,895,159 | 272,293 | SH | OTR | 1 | 0 | 272,293 | 0 | ||
| ALIBABA GROUP HLDG LTD | SPONSORED ADS | 01609W102 | 4,404,500 | 50,000 | SH | OTR | 1 | 0 | 50,000 | 0 | ||
| ALIGOS THERAPEUTICS INC | COM | 01626L105 | 2,683,739 | 2,816,391 | SH | OTR | 1 | 0 | 2,816,391 | 0 | ||
| ALLAKOS INC | COM | 01671P100 | 3,771,882 | 447,967 | SH | OTR | 1 | 0 | 447,967 | 0 | ||
| ALNYLAM PHARMACEUTICALS INC | COM | 02043Q107 | 24,953,250 | 105,000 | SH | OTR | 1 | 0 | 105,000 | 0 | ||
| ALTIMMUNE INC | COM NEW | 02155H200 | 44,422,403 | 2,700,450 | SH | OTR | 1 | 0 | 2,700,450 | 0 | ||
| AMYLYX PHARMACEUTICALS INC | COM | 03237H101 | 3,695,000 | 100,000 | SH | OTR | 1 | 0 | 100,000 | 0 | ||
| ANAPTYSBIO INC | COM | 032724106 | 81,462,731 | 2,628,678 | SH | OTR | 1 | 0 | 2,628,678 | 0 | ||
| ARCUS BIOSCIENCES INC | COM | 03969F109 | 3,058,986 | 147,920 | SH | OTR | 1 | 0 | 147,920 | 0 | ||
| ARS PHARMACEUTICALS INC | COM | 82835W108 | 3,492,719 | 409,463 | SH | OTR | 1 | 0 | 409,463 | 0 | ||
| ARVINAS INC | COM | 04335A105 | 1,026,300 | 30,000 | SH | OTR | 1 | 0 | 30,000 | 0 | ||
| ASCENDIS PHARMA A/S | SPONSORED ADR | 04351P101 | 4,407,672 | 36,090 | SH | OTR | 1 | 0 | 36,090 | 0 | ||
| ASLAN PHARMACEUTICALS LTD | ADS | 04522R101 | 1,931,373 | 5,364,925 | SH | OTR | 1 | 0 | 5,364,925 | 0 | ||
| ASTRAZENECA PLC | SPONSORED ADR | 046353108 | 11,526,000 | 170,000 | SH | OTR | 1 | 0 | 170,000 | 0 | ||
| ATHIRA PHARMA INC | COM | 04746L104 | 1,538,192 | 485,234 | SH | OTR | 1 | 0 | 485,234 | 0 | ||
| ATYR PHARMA INC | COM NEW | 002120202 | 270,312 | 123,430 | SH | OTR | 1 | 0 | 123,430 | 0 | ||
| AURINIA PHARMACEUTICALS INC | COM | 05156V102 | 864,000 | 200,000 | SH | OTR | 1 | 0 | 200,000 | 0 | ||
| AXSOME THERAPEUTICS INC | COM | 05464T104 | 24,681,600 | 320,000 | SH | OTR | 1 | 0 | 320,000 | 0 | ||
| BEAM THERAPEUTICS INC | COM | 07373V105 | 3,715,450 | 95,000 | SH | OTR | 1 | 0 | 95,000 | 0 | ||
| BEIGENE LTD | SPONSORED ADR | 07725L102 | 18,694,900 | 85,000 | SH | OTR | 1 | 0 | 85,000 | 0 | ||
| BIO RAD LABS INC | CL A | 090572207 | 8,830,290 | 21,000 | SH | OTR | 1 | 0 | 21,000 | 0 | ||
| BIOATLA INC | COM | 09077B104 | 25,773,627 | 3,124,076 | SH | OTR | 1 | 0 | 3,124,076 | 0 | ||
| BIOCRYST PHARMACEUTICALS INC | COM | 09058V103 | 16,646,000 | 1,450,000 | SH | OTR | 1 | 0 | 1,450,000 | 0 | ||
| BIOHAVEN LTD | COM | G1110E107 | 1,943,200 | 140,000 | SH | OTR | 1 | 0 | 140,000 | 0 | ||
| BIONTECH SE | SPONSORED ADS | 09075V102 | 4,506,600 | 30,000 | SH | OTR | 1 | 0 | 30,000 | 0 | ||
| BLUEBIRD BIO INC | COM | 09609G100 | 32,077,854 | 4,635,528 | SH | OTR | 1 | 0 | 4,635,528 | 0 | ||
| BLUEPRINT MEDICINES CORP | COM | 09627Y109 | 1,752,400 | 40,000 | SH | OTR | 1 | 0 | 40,000 | 0 | ||
| BOLT BIOTHERAPEUTICS INC | COM | 097702104 | 520,000 | 400,000 | SH | OTR | 1 | 0 | 400,000 | 0 | ||
| CELLDEX THERAPEUTICS INC NEW | COM NEW | 15117B202 | 944,527 | 21,192 | SH | OTR | 1 | 0 | 21,192 | 0 | ||
| COHERUS BIOSCIENCES INC | COM | 19249H103 | 917,928 | 115,900 | SH | OTR | 1 | 0 | 115,900 | 0 | ||
| CONCERT PHARMACEUTICALS INC | COM | 206022105 | 6,716,000 | 1,150,000 | SH | OTR | 1 | 0 | 1,150,000 | 0 | ||
| CRISPR THERAPEUTICS AG | NAMEN AKT | H17182108 | 406,500 | 10,000 | SH | OTR | 1 | 0 | 10,000 | 0 | ||
| CTI BIOPHARMA CORP | COM | 12648L601 | 1,803,000 | 300,000 | SH | OTR | 1 | 0 | 300,000 | 0 | ||
| CYTOKINETICS INC | COM NEW | 23282W605 | 5,040,200 | 110,000 | SH | OTR | 1 | 0 | 110,000 | 0 | ||
| CYTOMX THERAPEUTICS INC | COM | 23284F105 | 5,616,712 | 3,510,445 | SH | OTR | 1 | 0 | 3,510,445 | 0 | ||
| CULLINAN ONCOLOGY INC | COM | 230031106 | 8,537,387 | 809,231 | SH | OTR | 1 | 0 | 809,231 | 0 | ||
| DYNAVAX TECHNOLOGIES CORP | COM NEW | 268158201 | 3,192,000 | 300,000 | SH | OTR | 1 | 0 | 300,000 | 0 | ||
| EAGLE PHARMACEUTICALS INC | COM | 269796108 | 3,474,190 | 118,857 | SH | OTR | 1 | 0 | 118,857 | 0 | ||
| ELEVATION ONCOLOGY INC | COM | 28623U101 | 455,861 | 479,854 | SH | OTR | 1 | 0 | 479,854 | 0 | ||
| ENANTA PHARMACEUTICALS INC | COM | 29251M106 | 9,304,000 | 200,000 | SH | OTR | 1 | 0 | 200,000 | 0 | ||
| EVOLUS INC | COM | 30052C107 | 6,079,255 | 809,488 | SH | OTR | 1 | 0 | 809,488 | 0 | ||
| GALAPAGOS NV | SPON ADR | 36315X101 | 5,101,481 | 114,950 | SH | OTR | 1 | 0 | 114,950 | 0 | ||
| GENFIT S A | ADS | 372279109 | 5,255,924 | 1,197,522 | SH | OTR | 1 | 0 | 1,197,522 | 0 | ||
| GOSSAMER BIO INC | COM | 38341P102 | 217,000 | 100,000 | SH | OTR | 1 | 0 | 100,000 | 0 | ||
| GRAPHITE BIO INC | COM | 38870X104 | 3,652,000 | 1,100,000 | SH | OTR | 1 | 0 | 1,100,000 | 0 | ||
| HARMONY BIOSCIENCES HLDGS IN | COM | 413197104 | 15,494,120 | 281,200 | SH | OTR | 1 | 0 | 281,200 | 0 | ||
| HEALTH SCIENCES ACQ CORP 2 | ORD SHS | G4411D109 | 3,917,150 | 392,500 | SH | OTR | 1 | 0 | 392,500 | 0 | ||
| HERON THERAPEUTICS INC | COM | 427746102 | 9,389,835 | 3,755,934 | SH | OTR | 1 | 0 | 3,755,934 | 0 | ||
| IMMUNOCORE HLDGS PLC | ADS | 45258D105 | 23,147,592 | 405,600 | SH | OTR | 1 | 0 | 405,600 | 0 | ||
| IMMUNOGEN INC | COM | 45253H101 | 6,323,271 | 1,274,853 | SH | OTR | 1 | 0 | 1,274,853 | 0 | ||
| INSMED INC | COM PAR $.01 | 457669307 | 3,320,736 | 166,203 | SH | OTR | 1 | 0 | 166,203 | 0 | ||
| INTRA-CELLULAR THERAPIES INC | COM | 46116X101 | 12,700,800 | 240,000 | SH | OTR | 1 | 0 | 240,000 | 0 | ||
| IONIS PHARMACEUTICALS INC | COM | 462222100 | 7,554,000 | 200,000 | SH | OTR | 1 | 0 | 200,000 | 0 | ||
| ITEOS THERAPEUTICS INC | COM | 46565G104 | 4,232,151 | 216,700 | SH | OTR | 1 | 0 | 216,700 | 0 | ||
| KALVISTA PHARMACEUTICALS INC | COM | 483497103 | 21,607,975 | 3,196,446 | SH | OTR | 1 | 0 | 3,196,446 | 0 | ||
| KINIKSA PHARMACEUTICALS LTD | COM CL A | G5269C101 | 8,988,000 | 600,000 | SH | OTR | 1 | 0 | 600,000 | 0 | ||
| LEGEND BIOTECH CORP | SPONSORED ADS | 52490G102 | 2,995,200 | 60,000 | SH | OTR | 1 | 0 | 60,000 | 0 | ||
| LIANBIO | SPONSORED ADS | 53000N108 | 97,744 | 59,600 | SH | OTR | 1 | 0 | 59,600 | 0 | ||
| LILLY ELI & CO | COM | 532457108 | 7,316,800 | 20,000 | SH | OTR | 1 | 0 | 20,000 | 0 | ||
| METACRINE INC | COM | 59101E103 | 1,903,575 | 4,250,000 | SH | OTR | 1 | 0 | 4,250,000 | 0 | ||
| MIRATI THERAPEUTICS INC | COM | 60468T105 | 2,718,600 | 60,000 | SH | OTR | 1 | 0 | 60,000 | 0 | ||
| MIRUM PHARMACEUTICALS INC | COM | 604749101 | 21,840,000 | 1,120,000 | SH | OTR | 1 | 0 | 1,120,000 | 0 | ||
| MODERNA INC | COM | 60770K107 | 14,369,600 | 80,000 | SH | OTR | 1 | 0 | 80,000 | 0 | ||
| MOLECULAR PARTNERS AG | ADS | 60853G106 | 144,100 | 22,000 | SH | OTR | 1 | 0 | 22,000 | 0 | ||
| MOONLAKE IMMUNOTHERAPEUTICS | CLASS A ORD | 61559X104 | 2,579,997 | 245,714 | SH | OTR | 1 | 0 | 245,714 | 0 | ||
| NEKTAR THERAPEUTICS | COM | 640268108 | 371,069 | 164,190 | SH | OTR | 1 | 0 | 164,190 | 0 | ||
| NKARTA INC | COM | 65487U108 | 11,201,300 | 1,870,000 | SH | OTR | 1 | 0 | 1,870,000 | 0 | ||
| OLEMA PHARMACEUTICALS INC | COM | 68062P106 | 781,369 | 318,926 | SH | OTR | 1 | 0 | 318,926 | 0 | ||
| ORCHARD THERAPEUTICS PLC | SPON ADS | 68570P101 | 742,000 | 2,000,000 | SH | OTR | 1 | 0 | 2,000,000 | 0 | ||
| PARDES BIOSCIENCES INC | COM | 69945Q105 | 57,034 | 33,748 | SH | OTR | 1 | 0 | 33,748 | 0 | ||
| PYXIS ONCOLOGY INC | COMMON STOCK | 747324101 | 4,650,738 | 3,470,700 | SH | OTR | 1 | 0 | 3,470,700 | 0 | ||
| RELMADA THERAPEUTICS INC | COM | 75955J402 | 349,000 | 100,000 | SH | OTR | 1 | 0 | 100,000 | 0 | ||
| RENEO PHARMACEUTICALS INC | COM | 75974E103 | 71,268 | 30,587 | SH | OTR | 1 | 0 | 30,587 | 0 | ||
| REVIVA PHARMACEUTCLS HLDGS I | COM | 76152G100 | 102,531 | 24,125 | SH | OTR | 1 | 0 | 24,125 | 0 | ||
| SIO GENE THERAPIES INC | COM | 829399104 | 870,000 | 2,000,000 | SH | OTR | 1 | 0 | 2,000,000 | 0 | ||
| SURFACE ONCOLOGY INC | COM | 86877M209 | 352,311 | 429,647 | SH | OTR | 1 | 0 | 429,647 | 0 | ||
| TARSUS PHARMACEUTICALS INC | COM | 87650L103 | 29,343,236 | 2,001,585 | SH | OTR | 1 | 0 | 2,001,585 | 0 | ||
| TCR2 THERAPEUTICS INC | COM | 87808K106 | 2,735,660 | 2,738,947 | SH | OTR | 1 | 0 | 2,738,947 | 0 | ||
| THIRD HARMONIC BIO INC | COM | 88427A107 | 7,310,000 | 1,700,000 | SH | OTR | 1 | 0 | 1,700,000 | 0 | ||
| TONIX PHARMACEUTICALS HLDG C | COM NEW | 890260862 | 1,754,263 | 4,500,419 | SH | OTR | 1 | 0 | 4,500,419 | 0 | ||
| TSCAN THERAPEUTICS INC | COM | 89854M101 | 797,715 | 514,655 | SH | OTR | 1 | 0 | 514,655 | 0 | ||
| VAXCYTE INC | COM | 92243G108 | 14,385,000 | 300,000 | SH | OTR | 1 | 0 | 300,000 | 0 | ||
| VINCERX PHARMA INC | COM NEW | 92731L106 | 103,797 | 101,762 | SH | OTR | 1 | 0 | 101,762 | 0 | ||
| VIRIDIAN THERAPEUTICS INC | COM | 92790C104 | 20,240,339 | 692,925 | SH | OTR | 1 | 0 | 692,925 | 0 | ||
| ZYMEWORKS DEL INC | COM | 98985Y108 | 3,144,000 | 400,000 | SH | OTR | 1 | 0 | 400,000 | 0 | ||