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BAKER BROS. ADVISORS LP
> HALO
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 12/31/2019 | HALOZYME THERAPEUTICS, INC. | HALO | 0 | -299,969 | 0 | -4,653,000 | |
| 09/30/2019 | HALOZYME THERAPEUTICS, INC. | HALO | 299,969 | 0 | 4,653,000 | -500,000 | $15.51 |
| 06/30/2019 | HALOZYME THERAPEUTICS, INC. | HALO | 299,969 | 0 | 5,153,000 | 323,000 | $17.18 |
| 03/31/2019 | HALOZYME THERAPEUTICS, INC. | HALO | 299,969 | 0 | 4,830,000 | 441,000 | $16.10 |
| 12/31/2018 | HALOZYME THERAPEUTICS, INC. | HALO | 299,969 | -150,000 | 4,389,000 | -3,787,000 | $14.63 |
| 09/30/2018 | HALOZYME THERAPEUTICS, INC. | HALO | 449,969 | -833,960 | 8,176,000 | -13,484,000 | $18.17 |
| 06/30/2018 | HALOZYME THERAPEUTICS, INC. | HALO | 1,283,929 | -297,495 | 21,660,000 | -10,380,000 | $16.87 |
| 12/31/2017 | HALOZYME THERAPEUTICS, INC. | HALO | 1,581,424 | 0 | 32,040,000 | 4,571,000 | $20.26 |
| 09/30/2017 | HALOZYME THERAPEUTICS, INC. | HALO | 1,581,424 | 0 | 27,469,000 | 7,195,000 | $17.37 |
| 06/30/2017 | HALOZYME THERAPEUTICS, INC. | HALO | 1,581,424 | 189,917 | 20,274,000 | 2,240,000 | $12.82 |
| 03/31/2017 | HALOZYME THERAPEUTICS, INC. | HALO | 1,391,507 | 0 | 18,034,000 | 4,286,000 | $12.96 |
| 12/31/2016 | HALOZYME THERAPEUTICS, INC. | HALO | 1,391,507 | -339,550 | 13,748,000 | -7,163,000 | $9.88 |
| 09/30/2016 | HALOZYME THERAPEUTICS, INC. | HALO | 1,731,057 | -107,000 | 20,911,000 | 5,049,000 | $12.08 |
| 06/30/2016 | HALOZYME THERAPEUTICS, INC. | HALO | 1,838,057 | -93,000 | 15,862,000 | -2,425,000 | $8.63 |
| 03/31/2016 | HALOZYME THERAPEUTICS, INC. | HALO | 1,931,057 | 0 | 18,287,000 | -15,178,000 | $9.47 |
| 12/31/2015 | HALOZYME THERAPEUTICS, INC. | HALO | 1,931,057 | 161,281 | 33,465,000 | 21,590,000 | $17.33 |
| 09/30/2015 | HALOZYME THERAPEUTICS, INC. | HALO | 1,931,057 | 161,281 | 25,934,000 | 14,059,000 | $13.43 |
| 06/30/2015 | HALOZYME THERAPEUTICS, INC. | HALO | 1,931,057 | 161,281 | 43,603,000 | 31,728,000 | $22.58 |
| 03/31/2015 | HALOZYME THERAPEUTICS, INC. | HALO | 2,248,152 | 478,376 | 32,104,000 | 20,229,000 | $14.28 |
| 12/31/2014 | HALOZYME THERAPEUTICS, INC. | HALO | 2,776,143 | 1,006,367 | 26,790,000 | 14,915,000 | $9.65 |
| 09/30/2014 | HALOZYME THERAPEUTICS, INC. | HALO | 2,776,143 | 1,006,367 | 25,263,000 | 13,388,000 | $9.10 |
| 06/30/2014 | HALOZYME THERAPEUTICS, INC. | HALO | 2,776,143 | 1,006,367 | 27,428,000 | 15,553,000 | $9.88 |
| 03/31/2014 | HALOZYME THERAPEUTICS, INC. | HALO | 5,698,139 | 3,928,363 | 72,366,000 | 60,491,000 | $12.70 |
| 12/31/2013 | HALOZYME THERAPEUTICS, INC. | HALO | 6,297,026 | 4,527,250 | 94,392,000 | 82,517,000 | $14.99 |
| 09/30/2013 | HALOZYME THERAPEUTICS, INC. | HALO | 7,017,608 | 5,247,832 | 77,474,000 | 65,599,000 | $11.04 |
| 06/30/2013 | HALOZYME THERAPEUTICS, INC. | HALO | 6,553,150 | 4,783,374 | 52,098,000 | 40,223,000 | $7.95 |
| 03/31/2013 | HALOZYME THERAPEUTICS, INC. | HALO | 3,182,251 | 1,412,475 | 18,346,000 | 6,471,000 | $5.77 |
| 12/31/2012 | HALOZYME THERAPEUTICS, INC. | HALO | 1,769,776 | -12,452 | 11,875,000 | -1,563,000 | $6.71 |
| 09/30/2012 | HALOZYME THERAPEUTICS, INC. | HALO | 1,782,228 | 442,983 | 13,438,000 | 1,572,000 | $7.54 |
| 06/30/2012 | HALOZYME THERAPEUTICS, INC. | HALO | 1,339,245 | -450,350 | 11,866,000 | -10,969,000 | $8.86 |
| 03/31/2012 | HALOZYME THERAPEUTICS, INC. | HALO | 1,789,595 | 0 | 22,835,000 | 5,816,000 | $12.76 |
| 12/31/2011 | HALOZYME THERAPEUTICS, INC. | HALO | 1,789,595 | -1,143,217 | 17,019,000 | -988,000 | $9.51 |
| 09/30/2011 | HALOZYME THERAPEUTICS, INC. | HALO | 2,932,812 | -903,871 | 18,007,000 | -8,504,000 | $6.14 |
| 06/30/2011 | HALOZYME THERAPEUTICS, INC. | HALO | 3,836,683 | -109,876 | 26,511,000 | 49,000 | $6.91 |
| 03/31/2011 | HALOZYME THERAPEUTICS, INC. | HALO | 3,946,559 | 0 | 26,462,000 | -4,795,000 | $6.71 |
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