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BAKER BROS. ADVISORS LP
> SGEN
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 09/30/2020 | Seagen Inc. | SGEN | 0 | -47,269,424 | 0 | -8,032,021,000 | |
| 06/30/2020 | Seagen Inc. | SGEN | 47,269,424 | -2,790,816 | 8,032,021,000 | 2,256,071,000 | $169.92 |
| 03/31/2020 | Seagen Inc. | SGEN | 50,060,240 | 2,963 | 5,775,950,000 | 56,406,000 | $115.38 |
| 12/31/2019 | Seagen Inc. | SGEN | 50,057,277 | 0 | 5,719,544,000 | 1,444,653,000 | $114.26 |
| 09/30/2019 | Seagen Inc. | SGEN | 50,057,277 | 0 | 4,274,891,000 | 810,427,000 | $85.40 |
| 06/30/2019 | Seagen Inc. | SGEN | 50,057,277 | -992,483 | 3,464,464,000 | -274,420,000 | $69.21 |
| 03/31/2019 | Seagen Inc. | SGEN | 51,049,760 | 3,700 | 3,738,884,000 | 846,614,000 | $73.24 |
| 12/31/2018 | Seagen Inc. | SGEN | 51,046,060 | 0 | 2,892,270,000 | -1,044,402,000 | $56.66 |
| 09/30/2018 | Seagen Inc. | SGEN | 51,046,060 | 0 | 3,936,672,000 | 547,724,000 | $77.12 |
| 06/30/2018 | Seagen Inc. | SGEN | 51,046,060 | 5,320,504 | 3,388,948,000 | 942,631,000 | $66.39 |
| 04/30/2018 | Seagen Inc. | SGEN | 50,831,621 | 5,106,065 | 2,602,070,679 | 155,753,679 | $51.19 |
| 01/31/2018 | Seagen Inc. | SGEN | 49,818,661 | 4,093,105 | 2,605,515,970 | 117,587,970 | $52.30 |
| 12/31/2017 | Seagen Inc. | SGEN | 45,725,556 | 0 | 2,446,317,000 | -41,611,000 | $53.50 |
| 09/30/2017 | Seagen Inc. | SGEN | 45,725,556 | 0 | 2,487,928,000 | 122,088,000 | $54.41 |
| 06/30/2017 | Seagen Inc. | SGEN | 45,725,556 | 10,000 | 2,365,840,000 | -507,840,000 | $51.74 |
| 03/31/2017 | Seagen Inc. | SGEN | 45,715,556 | 3,700 | 2,873,680,000 | 461,465,000 | $62.86 |
| 12/31/2016 | Seagen Inc. | SGEN | 45,711,856 | 1,611,562 | 2,412,215,000 | 30,358,000 | $52.77 |
| 11/08/2016 | Seagen Inc. | SGEN | 45,959,548 | 2,720,581 | 2,730,916,250 | 983,629,250 | $59.42 |
| 09/30/2016 | Seagen Inc. | SGEN | 44,100,294 | 861,327 | 2,381,857,000 | 634,570,000 | $54.01 |
| 06/30/2016 | Seagen Inc. | SGEN | 43,238,967 | 3,700 | 1,747,287,000 | 230,161,000 | $40.41 |
| 03/31/2016 | Seagen Inc. | SGEN | 43,235,267 | 5,941,539 | 1,517,126,000 | -156,617,000 | $35.09 |
| 03/15/2016 | Seagen Inc. | SGEN | 43,353,334 | 24,030,387 | 1,376,468,355 | 928,756,355 | $31.75 |
| 03/08/2016 | Seagen Inc. | SGEN | 41,305,731 | 21,982,784 | 1,327,566,153 | 879,854,153 | $32.14 |
| 12/31/2015 | Seagen Inc. | SGEN | 37,293,728 | 17,970,781 | 1,673,743,000 | 1,226,031,000 | $44.88 |
| 09/30/2015 | Seagen Inc. | SGEN | 36,029,746 | 16,706,799 | 1,389,307,000 | 941,595,000 | $38.56 |
| 06/30/2015 | Seagen Inc. | SGEN | 30,870,262 | 11,547,315 | 1,494,121,000 | 1,046,409,000 | $48.40 |
| 03/31/2015 | Seagen Inc. | SGEN | 28,876,712 | 9,553,765 | 1,020,792,000 | 573,080,000 | $35.35 |
| 12/31/2014 | Seagen Inc. | SGEN | 27,861,720 | 8,538,773 | 895,197,000 | 447,485,000 | $32.13 |
| 09/30/2014 | Seagen Inc. | SGEN | 22,475,729 | 3,152,782 | 835,648,000 | 387,936,000 | $37.18 |
| 06/30/2014 | Seagen Inc. | SGEN | 22,472,229 | 3,149,282 | 859,562,000 | 411,850,000 | $38.25 |
| 03/31/2014 | Seagen Inc. | SGEN | 20,739,426 | 1,416,479 | 944,887,000 | 497,175,000 | $45.56 |
| 12/31/2013 | Seagen Inc. | SGEN | 20,735,926 | 1,412,979 | 827,156,000 | 379,444,000 | $39.89 |
| 09/30/2013 | Seagen Inc. | SGEN | 19,322,947 | 0 | 846,925,000 | 399,213,000 | $43.83 |
| 06/30/2013 | Seagen Inc. | SGEN | 19,322,947 | 0 | 607,900,000 | 160,188,000 | $31.46 |
| 03/31/2013 | Seagen Inc. | SGEN | 19,322,947 | 0 | 686,061,000 | 238,349,000 | $35.50 |
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