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BAKER BROS. ADVISORS LP
> SNTA
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 09/30/2016 | MADRIGAL PHARMACEUTICALS, INC. | SNTA | 0 | -2,021,728 | 0 | -526,000 | |
| 06/30/2016 | MADRIGAL PHARMACEUTICALS, INC. | SNTA | 2,021,728 | 2,021,728 | 526,000 | 526,000 | $0.26 |
| 12/31/2015 | MADRIGAL PHARMACEUTICALS, INC. | SNTA | 0 | -1,462,614 | 0 | -13,193,000 | |
| 09/30/2015 | MADRIGAL PHARMACEUTICALS, INC. | SNTA | 0 | -1,462,614 | 0 | -13,193,000 | |
| 06/30/2015 | MADRIGAL PHARMACEUTICALS, INC. | SNTA | 0 | -489,053 | 0 | -949,000 | |
| 03/31/2015 | MADRIGAL PHARMACEUTICALS, INC. | SNTA | 489,053 | -973,561 | 949,000 | -12,244,000 | $1.94 |
| 12/31/2014 | MADRIGAL PHARMACEUTICALS, INC. | SNTA | 500,000 | -962,614 | 1,325,000 | -11,868,000 | $2.65 |
| 09/30/2014 | MADRIGAL PHARMACEUTICALS, INC. | SNTA | 500,000 | -962,614 | 1,505,000 | -11,688,000 | $3.01 |
| 06/30/2014 | MADRIGAL PHARMACEUTICALS, INC. | SNTA | 500,000 | -962,614 | 2,045,000 | -11,148,000 | $4.09 |
| 03/31/2014 | MADRIGAL PHARMACEUTICALS, INC. | SNTA | 500,000 | -962,614 | 2,155,000 | -11,038,000 | $4.31 |
| 12/31/2013 | MADRIGAL PHARMACEUTICALS, INC. | SNTA | 500,000 | -962,614 | 2,620,000 | -10,573,000 | $5.24 |
| 09/30/2013 | MADRIGAL PHARMACEUTICALS, INC. | SNTA | 500,000 | -962,614 | 3,155,000 | -10,038,000 | $6.31 |
| 06/30/2013 | MADRIGAL PHARMACEUTICALS, INC. | SNTA | 1,399,040 | -63,574 | 6,981,000 | -6,212,000 | $4.99 |
| 03/31/2013 | MADRIGAL PHARMACEUTICALS, INC. | SNTA | 1,462,614 | 0 | 12,578,000 | -615,000 | $8.60 |
| 12/31/2012 | MADRIGAL PHARMACEUTICALS, INC. | SNTA | 1,462,614 | 150,143 | 13,193,000 | 3,192,000 | $9.02 |
| 09/30/2012 | MADRIGAL PHARMACEUTICALS, INC. | SNTA | 1,312,471 | 1,000,000 | 10,001,000 | 8,292,000 | $7.62 |
| 06/30/2012 | MADRIGAL PHARMACEUTICALS, INC. | SNTA | 312,471 | 312,471 | 1,709,000 | 1,709,000 | $5.47 |
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