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BAKER BROS. ADVISORS LP
> MDVN
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 09/30/2016 | MEDIVATION, INC. | MDVN | 0 | -329,876 | 0 | -19,892,000 | |
| 06/30/2016 | MEDIVATION, INC. | MDVN | 329,876 | 0 | 19,892,000 | 4,724,000 | $60.30 |
| 03/31/2016 | MEDIVATION, INC. | MDVN | 329,876 | -329,876 | 15,168,000 | -16,724,000 | $45.98 |
| 12/31/2015 | MEDIVATION, INC. | MDVN | 659,752 | -306,794 | 31,892,000 | -17,556,000 | $48.34 |
| 09/30/2015 | MEDIVATION, INC. | MDVN | 659,752 | -306,794 | 28,039,000 | -21,409,000 | $42.50 |
| 06/30/2015 | MEDIVATION, INC. | MDVN | 0 | -966,546 | 0 | -49,448,000 | |
| 03/31/2015 | MEDIVATION, INC. | MDVN | 0 | -966,546 | 0 | -49,448,000 | |
| 12/31/2014 | MEDIVATION, INC. | MDVN | 0 | -966,546 | 0 | -49,448,000 | |
| 09/30/2014 | MEDIVATION, INC. | MDVN | 0 | -966,546 | 0 | -49,448,000 | |
| 06/30/2014 | MEDIVATION, INC. | MDVN | 0 | -966,546 | 0 | -49,448,000 | |
| 03/31/2014 | MEDIVATION, INC. | MDVN | 0 | -398,331 | 0 | -25,421,000 | |
| 12/31/2013 | MEDIVATION, INC. | MDVN | 398,331 | -568,215 | 25,421,000 | -24,027,000 | $63.82 |
| 09/30/2013 | MEDIVATION, INC. | MDVN | 398,331 | -568,215 | 23,876,000 | -25,572,000 | $59.94 |
| 06/30/2013 | MEDIVATION, INC. | MDVN | 398,331 | -568,215 | 19,598,000 | -29,850,000 | $49.20 |
| 03/31/2013 | MEDIVATION, INC. | MDVN | 534,919 | -431,627 | 25,013,000 | -24,435,000 | $46.76 |
| 12/31/2012 | MEDIVATION, INC. | MDVN | 966,546 | 0 | 49,448,000 | -5,017,000 | $51.16 |
| 09/30/2012 | MEDIVATION, INC. | MDVN | 966,546 | 483,273 | 54,465,000 | 10,294,000 | $56.35 |
| 06/30/2012 | MEDIVATION, INC. | MDVN | 483,273 | -200,027 | 44,171,000 | -6,885,000 | $91.40 |
| 03/31/2012 | MEDIVATION, INC. | MDVN | 683,300 | 200,000 | 51,056,000 | 28,771,000 | $74.72 |
| 12/31/2011 | MEDIVATION, INC. | MDVN | 483,300 | 0 | 22,285,000 | 14,079,000 | $46.11 |
| 09/30/2011 | MEDIVATION, INC. | MDVN | 483,300 | -47,718 | 8,206,000 | -3,174,000 | $16.98 |
| 06/30/2011 | MEDIVATION, INC. | MDVN | 531,018 | -52,000 | 11,380,000 | 513,000 | $21.43 |
| 03/31/2011 | MEDIVATION, INC. | MDVN | 583,018 | 83,018 | 10,867,000 | 3,282,000 | $18.64 |
| 12/31/2010 | MEDIVATION, INC. | MDVN | 500,000 | 95,719 | 7,585,000 | 2,329,000 | $15.17 |
| 09/30/2010 | MEDIVATION, INC. | MDVN | 404,281 | 404,281 | 5,256,000 | 5,256,000 | $13.00 |
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