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BAKER BROS. ADVISORS LP
> GEVA
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2016 | SYNAGEVA BIOPHARMA CORP | GEVA | 0 | -8,363,462 | 0 | -387,145,000 | |
| 12/31/2015 | SYNAGEVA BIOPHARMA CORP | GEVA | 0 | -8,363,462 | 0 | -387,145,000 | |
| 09/30/2015 | SYNAGEVA BIOPHARMA CORP | GEVA | 0 | -8,363,462 | 0 | -387,145,000 | |
| 06/30/2015 | SYNAGEVA BIOPHARMA CORP | GEVA | 0 | -11,660,432 | 0 | -1,137,242,000 | |
| 03/31/2015 | SYNAGEVA BIOPHARMA CORP | GEVA | 11,660,432 | 3,296,970 | 1,137,242,000 | 750,097,000 | $97.53 |
| 12/31/2014 | SYNAGEVA BIOPHARMA CORP | GEVA | 10,660,432 | 2,296,970 | 989,182,000 | 602,037,000 | $92.79 |
| 09/30/2014 | SYNAGEVA BIOPHARMA CORP | GEVA | 10,660,432 | 2,296,970 | 733,225,000 | 346,080,000 | $68.78 |
| 06/30/2014 | SYNAGEVA BIOPHARMA CORP | GEVA | 10,660,432 | 2,296,970 | 1,117,213,000 | 730,068,000 | $104.80 |
| 03/31/2014 | SYNAGEVA BIOPHARMA CORP | GEVA | 10,648,182 | 2,284,720 | 883,480,000 | 496,335,000 | $82.97 |
| 12/31/2013 | SYNAGEVA BIOPHARMA CORP | GEVA | 10,273,182 | 1,909,720 | 664,880,000 | 277,735,000 | $64.72 |
| 09/30/2013 | SYNAGEVA BIOPHARMA CORP | GEVA | 10,273,182 | 1,909,720 | 651,238,000 | 264,093,000 | $63.39 |
| 06/30/2013 | SYNAGEVA BIOPHARMA CORP | GEVA | 9,223,182 | 859,720 | 387,189,000 | 44,000 | $41.98 |
| 03/31/2013 | SYNAGEVA BIOPHARMA CORP | GEVA | 9,223,182 | 859,720 | 506,536,000 | 119,391,000 | $54.92 |
| 12/31/2012 | SYNAGEVA BIOPHARMA CORP | GEVA | 8,363,462 | -1 | 387,145,000 | -59,715,000 | $46.29 |
| 09/30/2012 | SYNAGEVA BIOPHARMA CORP | GEVA | 8,363,463 | 885,999 | 446,860,000 | 143,573,000 | $53.43 |
| 06/30/2012 | SYNAGEVA BIOPHARMA CORP | GEVA | 7,477,464 | 0 | 303,287,000 | 35,070,000 | $40.56 |
| 03/31/2012 | SYNAGEVA BIOPHARMA CORP | GEVA | 7,477,464 | 1,293,890 | 268,217,000 | 103,549,000 | $35.87 |
| 12/31/2011 | SYNAGEVA BIOPHARMA CORP | GEVA | 6,183,574 | 6,183,574 | 164,668,000 | 164,668,000 | $26.63 |
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