The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
Aclaris therapeutics Common 00461U105 79,427 4,191,397 SH   SOLE   4,191,397 0 0
Advanced Accelerator Applications S.A. Common 00790T100 15,962 455,798 SH   SOLE   455,798 0 0
Agile Therapeutics, Inc. Common 00847L100 12,544 2,019,955 SH   SOLE   2,019,955 0 0
Akari Therapeutics Plc ADR 00972G108 7,390 527,842 SH   SOLE   527,842 0 0
Ascendis Pharma ADR 04351P101 26,329 1,419,332 SH   SOLE   1,419,332 0 0
Biotie Therapies Corp. ADR 09074D103 32,544 1,220,234 SH   SOLE   1,220,234 0 0
Capnia, Inc. Common 14066L105 8,885 7,466,352 SH   SOLE   7,466,352 0 0
Capnia, Inc. Warrant 14066L113 215 932,910 SH   SOLE   932,910 0 0
Carbylan Therapeutics Common 141384107 2,691 4,204,562 SH   SOLE   4,204,562 0 0
ChemoCentryx, Inc. Common 16383L106 2,211 887,906 SH   SOLE   887,906 0 0
Codexis, Inc. Common 192005106 17,333 5,573,319 SH   SOLE   5,573,319 0 0
Dynavax Technologies Corporation Common 268158201 6,883 357,755 SH   SOLE   357,755 0 0
Eiger BioPharmaceuticals Common 28249U105 26,825 1,599,592 SH   SOLE   1,599,592 0 0
Kite Pharma, Inc. Common 49803L109 8,869 193,193 SH   SOLE   193,193 0 0
MEI Pharma, Inc. Common 55279B202 3,487 2,767,718 SH   SOLE   2,767,718 0 0
Nabriva Therapeutics AG ADR 62957M104 28,239 3,151,700 SH   SOLE   3,151,700 0 0
Ocera Therapeutics, Inc. Common 67552A108 451 153,331 SH   SOLE   153,331 0 0
Palatin Technologies, Inc. Common 696077403 127 234,909 SH   SOLE   234,909 0 0
ProNAi Therapeutics, Inc. Common 74346L101 16,434 2,438,270 SH   SOLE   2,438,270 0 0
Regenxbio Inc. Common 75901B107 10,697 990,449 SH   SOLE   990,449 0 0
ReVance Therapeutics, Inc. Common 761330109 1,886 77,373 SH   SOLE   77,373 0 0
Sagent Pharmaceuticals, Inc. Common 786692103 79,102 6,499,737 SH   SOLE   6,499,737 0 0
Trevena, Inc. Common 89532E109 9,924 1,200,000 SH   SOLE   1,200,000 0 0
Zosano Pharma Corp Common 98979H103 227 98,515 SH   SOLE   98,515 0 0