The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
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COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ARRAY BIOPHARMA INC NOTE 04269XAA3 18,140 22,534,000 PRN   SOLE   22,534,000 0 0
AKARI THERAPEUTICS PLC SPONSORED ADR 00972G108 1,292 92,303 SH   SOLE   92,303 0 0
ASSEMBLY BIOSCIENCES INC COM 045396108 10,533 2,098,302 SH   SOLE   2,098,302 0 0
ATYR PHARMA INC COM 002120103 295 74,959 SH   SOLE   74,959 0 0
BEIGENE LTD SPONSORED ADR 07725L102 462 15,766 SH   SOLE   15,766 0 0
COLLEGIUM PHARMACEUTICAL INC COM 19459J104 8,587 473,123 SH   SOLE   473,123 0 0
CELATOR PHARMACEUTICALS INC COM 15089R102 10,479 950,000 SH   SOLE   950,000 0 0
CYTOKINETICS INC COM 23282W605 14,472 2,052,800 SH   SOLE   2,052,800 0 0
TARGACEPT INC NOTE 87611RAA6 669 669,166 PRN   SOLE   669,166 0 0
EIGER BIOPHARMACEUTICALS INC COM 28249U105 3,179 189,545 SH   SOLE   189,545 0 0
ENANTA PHARMACEUTICALS INC COM 29251M106 7,060 240,383 SH   SOLE   240,383 0 0
EPIZYME INC COM 29428V104 19,379 1,598,900 SH   SOLE   1,598,900 0 0
FIBROGEN INC COM 31572Q808 18,389 863,745 SH   SOLE   863,745 0 0
FLEX PHARMA INC COM 33938A105 6,318 575,925 SH   SOLE   575,925 0 0
FIVE PRIME THERAPEUTICS INC COM 33830X104 20,346 500,757 SH   SOLE   500,757 0 0
FORWARD PHARMA A/S SPONSORED ADR 34986J105 1,649 97,024 SH   SOLE   97,024 0 0
GLOBAL BLOOD THERAPEUTICS INC COM 37890U108 445 28,032 SH   SOLE   28,032 0 0
GALAPAGOS NV SPONSORED ADR 36315X101 10,317 246,691 SH   SOLE   246,691 0 0
IRONWOOD PHARMACEUTICALS INC COM 46333X108 22,552 2,061,417 SH   SOLE   2,061,417 0 0
KINDRED BIOSCIENCES INC COM 494577109 4,943 1,432,765 SH   SOLE   1,432,765 0 0
KITE PHARMA INC COM 49803L109 6,887 150,000 SH   SOLE   150,000 0 0
ARRAY BIOPHARMA INC COM 04269X905 1,534 520,000 SH Call SOLE   520,000 0 0
CYTOKINETICS INC COM 23282W905 1,763 250,000 SH Call SOLE   250,000 0 0
GILEAD SCIENCES INC COM 375558903 13,779 150,000 SH Call SOLE   150,000 0 0
IMMUNOGEN INC COM 45253H901 2,552 299,500 SH Call SOLE   299,500 0 0
IRONWOOD PHARMACEUTICALS INC COM 46333X908 3,282 300,000 SH Call SOLE   300,000 0 0
SPDR SERIES TRUST S&P BIOTECH COM 78464A900 15,353 297,200 SH Call SOLE   297,200 0 0
ZAFGEN INC COM 98885E903 67 10,000 SH Call SOLE   10,000 0 0
SPARK THERAPEUTICS INC COM 84652J103 257 8,700 SH   SOLE   8,700 0 0
RETROPHIN INC COM 761299106 16,735 1,225,084 SH   SOLE   1,225,084 0 0
ACCELERON PHARMA INC COM 00434H108 7,133 270,289 SH   SOLE   270,289 0 0
AIMMUNE THERAPEUTICS INC COM 00900T107 7,070 521,366 SH   SOLE   521,366 0 0
LOXO ONCOLOGY INC COM 548862101 4,109 150,308 SH   SOLE   150,308 0 0
EDITAS MEDICINE INC COM 28106W103 3,037 87,921 SH   SOLE   87,921 0 0
NABRIVA THERAPTCS AG SPONSORED ADR 62957M104 6,342 707,817 SH   SOLE   707,817 0 0
SYNDAX PHARMACEUTICALS INC COM 87164F105 6,804 510,829 SH   SOLE   510,829 0 0
KURA ONCOLOGY INC COM 50127T109 9,984 2,465,286 SH   SOLE   2,465,286 0 0