The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete. | |||||||||||||||||
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UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 13F FORM 13F INFORMATION TABLE |
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| COLUMN 1 | COLUMN 2 | COLUMN 3 | COLUMN 4 | COLUMN 5 | COLUMN 6 | COLUMN 7 | COLUMN 8 | ||||
| VALUE | SHRS OR | SH/ | PUT/ | INVESTMENT | OTHER | VOTING AUTHORITY | |||||
| NAME OF ISSUER | TITLE OF CLASS | CUSIP | (x$1000) | PRN AMT | PRN | CALL | DISCRETION | MANAGER | SOLE | SHARED | NONE |
| ACHAOGEN INC | COM | 004449104 | 155 | 32,300 | SH | SOLE | 0 | 32,300 | 0 | 0 | |
| ADVERUM BIOTECHNOLOGIES INC | COM | 00773U108 | 91 | 22,236 | SH | SOLE | 0 | 22,236 | 0 | 0 | |
| AGIOS PHARMACEUTICALS INC | COM | 00847X104 | 38,976 | 737,900 | SH | SOLE | 0 | 737,900 | 0 | 0 | |
| ALDER BIOPHARMACEUTICALS INC | COM | 014339105 | 23,022 | 702,539 | SH | SOLE | 0 | 702,539 | 0 | 0 | |
| ALEXION PHARMACEUTICALS INC | COM | 015351109 | 5,565 | 45,410 | SH | SOLE | 0 | 45,410 | 0 | 0 | |
| AMICUS THERAPEUTICS INC | COM | 03152W109 | 94,361 | 12,751,536 | SH | SOLE | 0 | 12,751,536 | 0 | 0 | |
| ARIAD PHARMACEUTICALS INC | COM | 04033A100 | 29,276 | 2,138,471 | SH | SOLE | 0 | 2,138,471 | 0 | 0 | |
| ARRAY BIOPHARMA INC | COM | 04269X105 | 112,442 | 16,658,072 | SH | SOLE | 0 | 16,658,072 | 0 | 0 | |
| ARRAY BIOPHARMA INC | NOTE 3.000% 6/0 | 04269XAA3 | 4,761 | 4,000,000 | PRN | SOLE | 0 | 4,000,000 | 0 | 0 | |
| ASTRAZENECA PLC | SPONSORED ADR | 046353108 | 9,475 | 288,356 | SH | SOLE | 0 | 288,356 | 0 | 0 | |
| ATARA BIOTHERAPEUTICS INC | COM | 046513107 | 43,242 | 2,021,617 | SH | SOLE | 0 | 2,021,617 | 0 | 0 | |
| AUDENTES THERAPEUTICS INC | COM | 05070R104 | 14,903 | 916,626 | SH | SOLE | 0 | 916,626 | 0 | 0 | |
| AURINIA PHARMACEUTICALS INC | COM | 05156V102 | 565 | 187,610 | SH | SOLE | 0 | 187,610 | 0 | 0 | |
| BIOGEN INC | COM | 09062X103 | 212 | 677 | SH | SOLE | 0 | 677 | 0 | 0 | |
| BLUEPRINT MEDICINES CORP | COM | 09627Y109 | 818 | 27,539 | SH | SOLE | 0 | 27,539 | 0 | 0 | |
| BOSTON SCIENTIFIC CORP | COM | 101137107 | 25,529 | 1,072,638 | SH | SOLE | 0 | 1,072,638 | 0 | 0 | |
| CASTLIGHT HEALTH INC | CL B | 14862Q100 | 43 | 10,229 | SH | SOLE | 0 | 10,229 | 0 | 0 | |
| CENTENE CORP DEL | COM | 15135B101 | 31,075 | 464,077 | SH | SOLE | 0 | 464,077 | 0 | 0 | |
| CHARLES RIV LABS INTL INC | COM | 159864107 | 10,593 | 127,106 | SH | SOLE | 0 | 127,106 | 0 | 0 | |
| CHIMERIX INC | COM | 16934W106 | 17,811 | 3,214,946 | SH | SOLE | 0 | 3,214,946 | 0 | 0 | |
| CLOVIS ONCOLOGY INC | COM | 189464100 | 73,902 | 2,049,985 | SH | SOLE | 0 | 2,049,985 | 0 | 0 | |
| CYTOMX THERAPEUTICS INC | COM | 23284F105 | 11,206 | 714,692 | SH | SOLE | 0 | 714,692 | 0 | 0 | |
| DEXCOM INC | COM | 252131107 | 216 | 2,460 | SH | SOLE | 0 | 2,460 | 0 | 0 | |
| ENDOLOGIX INC | COM | 29266S106 | 44,552 | 3,480,644 | SH | SOLE | 0 | 3,480,644 | 0 | 0 | |
| FATE THERAPEUTICS INC | COM | 31189P102 | 4,446 | 1,425,158 | SH | SOLE | 0 | 1,425,158 | 0 | 0 | |
| FIRST TR EXCHANGE TRADED FD | NY ARCA BIOTECH | 33733E203 | 308 | 3,090 | SH | SOLE | 0 | 3,090 | 0 | 0 | |
| GW PHARMACEUTICALS PLC | ADS | 36197T103 | 72,460 | 545,922 | SH | SOLE | 0 | 545,922 | 0 | 0 | |
| HUMANA INC | COM | 444859102 | 246 | 1,390 | SH | SOLE | 0 | 1,390 | 0 | 0 | |
| INCYTE CORP | COM | 45337C102 | 56,351 | 597,638 | SH | SOLE | 0 | 597,638 | 0 | 0 | |
| INTRA CELLULAR THERAPIES INC | COM | 46116X101 | 5,132 | 336,759 | SH | SOLE | 0 | 336,759 | 0 | 0 | |
| INVITAE CORP | COM | 46185L103 | 4,471 | 510,369 | SH | SOLE | 0 | 510,369 | 0 | 0 | |
| IRONWOOD PHARMACEUTICALS INC | COM CL A | 46333X108 | 6,486 | 408,462 | SH | SOLE | 0 | 408,462 | 0 | 0 | |
| MODEL N INC | COM | 607525102 | 17,231 | 1,550,959 | SH | SOLE | 0 | 1,550,959 | 0 | 0 | |
| MOLINA HEALTHCARE INC | COM | 60855R100 | 45,382 | 778,160 | SH | SOLE | 0 | 778,160 | 0 | 0 | |
| NANOSTRING TECHNOLOGIES INC | COM | 63009R109 | 24,724 | 1,237,435 | SH | SOLE | 0 | 1,237,435 | 0 | 0 | |
| NEURODERM LTD | ORD SHS | M74231107 | 14,889 | 805,246 | SH | SOLE | 0 | 805,246 | 0 | 0 | |
| NEVRO CORP | COM | 64157F103 | 23,724 | 227,267 | SH | SOLE | 0 | 227,267 | 0 | 0 | |
| OPHTHOTECH CORP | COM | 683745103 | 23,303 | 505,154 | SH | SOLE | 0 | 505,154 | 0 | 0 | |
| OXFORD IMMUNOTEC GLOBAL PLC | ORD SHS | G6855A103 | 17,975 | 1,431,119 | SH | SOLE | 0 | 1,431,119 | 0 | 0 | |
| PENUMBRA INC | COM | 70975L107 | 51,135 | 672,918 | SH | SOLE | 0 | 672,918 | 0 | 0 | |
| PORTOLA PHARMACEUTICALS INC | COM | 737010108 | 20,823 | 916,927 | SH | SOLE | 0 | 916,927 | 0 | 0 | |
| PROQR THRAPEUTICS N V | SHS EURO | N71542109 | 3,841 | 575,863 | SH | SOLE | 0 | 575,863 | 0 | 0 | |
| PROTHENA CORP PLC | SHS | G72800108 | 42,078 | 701,659 | SH | SOLE | 0 | 701,659 | 0 | 0 | |
| PUMA BIOTECHNOLOGY INC | COM | 74587V107 | 44,406 | 662,286 | SH | SOLE | 0 | 662,286 | 0 | 0 | |
| SAREPTA THERAPEUTICS INC | COM | 803607100 | 39,327 | 640,400 | SH | SOLE | 0 | 640,400 | 0 | 0 | |
| SEATTLE GENETICS INC | COM | 812578102 | 96,217 | 1,781,470 | SH | SOLE | 0 | 1,781,470 | 0 | 0 | |
| SPECTRANETICS CORP | COM | 84760C107 | 8,399 | 334,741 | SH | SOLE | 0 | 334,741 | 0 | 0 | |
| SYROS PHARMACEUTICALS INC | COM | 87184Q107 | 11,736 | 892,782 | SH | SOLE | 0 | 892,782 | 0 | 0 | |
| UNITEDHEALTH GROUP INC | COM | 91324P102 | 255 | 1,820 | SH | SOLE | 0 | 1,820 | 0 | 0 | |
| VCA INC | COM | 918194101 | 6,368 | 91,000 | SH | SOLE | 0 | 91,000 | 0 | 0 | |
| WAVE LIFE SCIENCES LTD | SHS | Y95308105 | 22,788 | 701,822 | SH | SOLE | 0 | 701,822 | 0 | 0 | |