The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
Ac Immune Sa SHS H00263105 10,360 1,000,000 SH   SOLE   1,000,000 0 0
Aclaris Therapeutics Inc COM 00461U105 28,958 971,100 SH   SOLE   971,100 0 0
Adecoagro S A COM L00849106 1,074 93,700 SH   SOLE   93,700 0 0
Adecoagro S A COM L00849106 15,528 1,355,000 SH   DFND 1 1,355,000 0 0
Alexion Pharmaceuticals Inc COM 015351109 9,663 79,700 SH   SOLE   79,700 0 0
Alibaba Group Hldg Ltd SPONSORED ADS 01609W102 3,300 30,600 SH   SOLE   30,600 0 0
Alkermes Plc SHS G01767105 73,593 1,258,000 SH   SOLE   1,258,000 0 0
Allergan Plc SHS G0177J108 9,557 40,000 SH Put SOLE   40,000 0 0
Alphabet Inc CAP STK CL A 02079K305 300,356 354,277 SH   SOLE   354,277 0 0
Amazon Com Inc COM 023135106 276,708 312,121 SH   SOLE   312,121 0 0
Ameren Corp COM 023608102 10,017 183,500 SH   SOLE   183,500 0 0
American Elec Pwr Inc COM 025537101 9,734 145,000 SH   SOLE   145,000 0 0
Anadarko Pete Corp COM 032511107 30,492 491,800 SH   SOLE   491,800 0 0
Array Biopharma Inc COM 04269X105 17,735 1,983,800 SH   SOLE   1,983,800 0 0
Autodesk Inc COM 052769106 381,929 4,416,900 SH   SOLE   4,416,900 0 0
Avexis Inc COM 05366U100 18,937 249,067 SH   SOLE   249,067 0 0
Axovant Sciences Ltd COM G0750W104 8,611 576,400 SH   SOLE   576,400 0 0
Banco Macro Sa SPON ADR B 05961W105 53,312 614,900 SH   DFND 1 614,900 0 0
Bank Amer Corp COM 060505104 339,519 14,392,500 SH   SOLE   14,392,500 0 0
Bio Rad Labs Inc CL A 090572207 4,007 20,100 SH   SOLE   20,100 0 0
Biogen Inc COM 09062X103 91,186 333,500 SH   SOLE   333,500 0 0
Biogen Inc COM 09062X103 2,734 10,000 SH Call SOLE   10,000 0 0
Bioverativ Inc COM 09075E100 31,944 586,551 SH   SOLE   586,551 0 0
Bluebird Bio Inc COM 09609G100 15,304 168,362 SH   SOLE   168,362 0 0
Blueprint Medicines Corp COM 09627Y109 5,179 129,500 SH   SOLE   129,500 0 0
Boston Scientific Corp COM 101137107 22,726 913,800 SH   SOLE   913,800 0 0
Bristol Myers Squibb Co COM 110122108 143,525 2,639,300 SH   SOLE   2,639,300 0 0
Bristol Myers Squibb Co COM 110122108 43,504 800,000 SH Call SOLE   800,000 0 0
Broadcom Ltd SHS Y09827109 173,005 790,120 SH   SOLE   790,120 0 0
Bwx Technologies Inc COM 05605H100 9,520 200,000 SH   SOLE   200,000 0 0
Cabot Oil & Gas Corp COM 127097103 267,637 11,193,500 SH   SOLE   11,193,500 0 0
Canadian Nat Res Ltd COM 136385101 24,143 736,300 SH   SOLE   736,300 0 0
Celgene Corp COM 151020104 26,516 213,100 SH   SOLE   213,100 0 0
Charter Communications Inc N CL A 16119P108 46,970 143,498 SH   SOLE   143,498 0 0
Cheniere Energy Inc COM NEW 16411R208 59,202 1,252,424 SH   SOLE   1,252,424 0 0
Cigna Corporation COM 125509109 1,831 12,500 SH   SOLE   12,500 0 0
Citizens Finl Group Inc COM 174610105 81,949 2,371,900 SH   SOLE   2,371,900 0 0
Clovis Oncology Inc COM 189464100 128,998 2,026,045 SH   SOLE   2,026,045 0 0
Coherus Biosciences Inc COM 19249H103 8,910 421,300 SH   SOLE   421,300 0 0
Comcast Corp New CL A 20030N101 209,216 5,565,738 SH   SOLE   5,565,738 0 0
Comerica Inc COM 200340107 2,078 30,300 SH   SOLE   30,300 0 0
Community Health Sys Inc New COM 203668108 16,587 1,870,000 SH   SOLE   1,870,000 0 0
Computer Sciences Corp COM 205363104 1,725 25,000 SH Put SOLE   25,000 0 0
Comstock Res Inc NOTE 9.500% 6/1 205768AN4 16,104 18,660,921 PRN   SOLE   18,660,921 0 0
Comstock Res Inc NOTE 9.500% 6/1 205768AN4 3,216 3,726,000 PRN   OTR   3,726,000 0 0
Comstock Res Inc NOTE 7.750% 4/0 205768AM6 21,510 25,148,133 PRN   SOLE   25,148,133 0 0
Comstock Res Inc NOTE 7.750% 4/0 205768AM6 4,313 5,043,011 PRN   OTR   5,043,011 0 0
Constellation Brands Inc CL A 21036P108 71,521 441,300 SH   SOLE   441,300 0 0
Csx Corp COM 126408103 103,453 2,222,400 SH   SOLE   2,222,400 0 0
Davita Inc COM 23918K108 87,196 1,282,855 SH   SOLE   1,282,855 0 0
Diamondback Energy Inc COM 25278X109 119,874 1,155,800 SH   SOLE   1,155,800 0 0
Dicks Sporting Goods Inc COM 253393102 31,176 640,700 SH   SOLE   640,700 0 0
Dow Chem Co COM 260543103 607,680 9,563,738 SH   SOLE   9,563,738 0 0
Eaton Corp Plc SHS G29183103 32,070 432,500 SH   SOLE   432,500 0 0
Electronic Arts Inc COM 285512109 161,342 1,802,300 SH   SOLE   1,802,300 0 0
Encana Corp COM 292505104 153,814 13,135,300 SH   SOLE   13,135,300 0 0
Eog Res Inc COM 26875P101 8,423 86,350 SH   SOLE   86,350 0 0
Exelon Corp COM 30161N101 11,701 325,200 SH   SOLE   325,200 0 0
Facebook Inc CL A 30303M102 422,448 2,973,939 SH   SOLE   2,973,939 0 0
Firstenergy Corp COM 337932107 54,116 1,700,700 SH   SOLE   1,700,700 0 0
General Dynamics Corp COM 369550108 42,116 224,976 SH   SOLE   224,976 0 0
Global Blood Therapeutics In COM 37890U108 11,785 319,800 SH   SOLE   319,800 0 0
Grupo Financiero Galicia S A SP ADR 10 SH B 399909100 25,174 664,921 SH   SOLE   664,921 0 0
Grupo Financiero Galicia S A SP ADR 10 SH B 399909100 58,228 1,537,970 SH   DFND 1 1,537,970 0 0
Grupo Supervielle S A SPONSORED ADR 40054A108 45,005 2,647,361 SH   DFND 1 2,647,361 0 0
Halliburton Co COM 406216101 886 18,000 SH   SOLE   18,000 0 0
Healthequity Inc COM 42226A107 16,942 399,100 SH   SOLE   399,100 0 0
Honeywell Intl Inc COM 438516106 106,814 855,400 SH   SOLE   855,400 0 0
Humana Inc COM 444859102 18,140 88,000 SH   SOLE   88,000 0 0
Huntington Bancshares Inc COM 446150104 8,108 605,500 SH   SOLE   605,500 0 0
Ignyta Inc COM 451731103 6,073 706,200 SH   SOLE   706,200 0 0
Impax Laboratories Inc COM 45256B101 12,276 970,400 SH   SOLE   970,400 0 0
Intelsat S A COM L5140P101 15,563 3,750,000 SH   SOLE   3,750,000 0 0
Irhythm Technologies Inc COM 450056106 15,179 403,700 SH   SOLE   403,700 0 0
L3 Technologies Inc COM 502413107 27,306 165,200 SH   SOLE   165,200 0 0
Loxo Oncology Inc COM 548862101 3,855 91,600 SH   SOLE   91,600 0 0
Lyondellbasell Industries N SHS - A - N53745100 173,725 1,905,091 SH   SOLE   1,905,091 0 0
Mcdonalds Corp COM 580135101 15,216 117,400 SH   SOLE   117,400 0 0
Medicines Co COM 584688105 53,550 1,095,100 SH   SOLE   1,095,100 0 0
Microsoft Corp COM 594918104 246,011 3,735,360 SH   SOLE   3,735,360 0 0
Monsanto Co New COM 61166W101 38,907 343,700 SH   SOLE   343,700 0 0
Nektar Therapeutics COM 640268108 10,644 453,500 SH   SOLE   453,500 0 0
Nextera Energy Inc COM 65339F101 14,904 116,100 SH   SOLE   116,100 0 0
Nii Hldgs Inc COM PAR $0.001 62913F508 3,763 2,894,900 SH   SOLE   2,894,900 0 0
Northrop Grumman Corp COM 666807102 29,849 125,500 SH   SOLE   125,500 0 0
Oi S A SPONSORED ADR 670851500 33,951 5,215,203 SH   SOLE   5,215,203 0 0
Olin Corp COM PAR $1 680665205 59,725 1,817,000 SH   SOLE   1,817,000 0 0
Oncobiologics Inc *W EXP 02/18/201 68235M113 80 100,000 SH   SOLE   100,000 0 0
Oncobiologics Inc *W EXP 05/18/201 68235M121 50 100,000 SH   SOLE   100,000 0 0
Oneok Inc New COM 682680103 58,514 1,055,454 SH   SOLE   1,055,454 0 0
Pacira Pharmaceuticals Inc COM 695127100 54,989 1,205,900 SH   SOLE   1,205,900 0 0
Pampa Energia S A SPONS ADR LVL I 697660207 155,357 2,865,306 SH   SOLE   2,865,306 0 0
Pampa Energia S A SPONS ADR LVL I 697660207 119,268 2,199,706 SH   DFND 1 2,199,706 0 0
Parsley Energy Inc CL A 701877102 110,072 3,385,800 SH   SOLE   3,385,800 0 0
Pioneer Nat Res Co COM 723787107 987 5,300 SH   SOLE   5,300 0 0
Pnc Finl Svcs Group Inc COM 693475105 111,883 930,500 SH   SOLE   930,500 0 0
Powershares Qqq Trust UNIT SER 1 73935A104 18,202 137,500 SH Put SOLE   137,500 0 0
Ptc Inc COM 69370C100 75,399 1,434,800 SH   SOLE   1,434,800 0 0
Puma Biotechnology Inc COM 74587V107 28,681 771,000 SH   SOLE   771,000 0 0
Ralph Lauren Corp CL A 751212101 20,397 249,900 SH   SOLE   249,900 0 0
Regions Finl Corp New COM 7591EP100 10,209 702,600 SH   SOLE   702,600 0 0
Revance Therapeutics Inc COM 761330109 5,751 276,500 SH   SOLE   276,500 0 0
Reynolds American Inc COM 761713106 5,042 80,000 SH   SOLE   80,000 0 0
Rice Energy Inc COM 762760106 173,431 7,317,760 SH   SOLE   7,317,760 0 0
Rockwell Collins Inc COM 774341101 31,402 323,200 SH   SOLE   323,200 0 0
Royal Bk Of Scotland Plc NOTE 8.000%12/3 780099CK1 23,983 24,100,000 PRN   SOLE   24,100,000 0 0
Royal Bk Scotland Group Plc NOTE 8.625%12/3 780097BB6 12,351 11,850,000 PRN   SOLE   11,850,000 0 0
Salesforce Com Inc COM 79466L302 98,336 1,192,100 SH   SOLE   1,192,100 0 0
Sanofi RIGHT 12/31/2020 80105N113 3,287 7,305,164 SH   SOLE   7,305,164 0 0
Sarepta Therapeutics Inc COM 803607100 18,911 638,900 SH   SOLE   638,900 0 0
Select Sector Spdr Tr SBI INT-ENERGY 81369Y506 9,073 129,800 SH   SOLE   129,800 0 0
Select Sector Spdr Tr SBI INT-ENERGY 81369Y506 8,982 128,500 SH Call SOLE   128,500 0 0
Select Sector Spdr Tr SBI HEALTHCARE 81369Y209 1,859 25,000 SH Put SOLE   25,000 0 0
Sempra Energy COM 816851109 15,437 139,700 SH   SOLE   139,700 0 0
Southwest Airls Co COM 844741108 98,168 1,826,035 SH   SOLE   1,826,035 0 0
Spark Therapeutics Inc COM 84652J103 10,426 195,469 SH   SOLE   195,469 0 0
Spdr Gold Trust GOLD SHS 78463V107 16,550 139,400 SH Call SOLE   139,400 0 0
Spdr S&P 500 Etf Tr TR UNIT 78462F103 310,870 1,318,700 SH Call SOLE   1,318,700 0 0
Spdr S&P 500 Etf Tr TR UNIT 78462F103 764,976 3,245,000 SH Put SOLE   3,245,000 0 0
Syngenta Ag SPONSORED ADR 87160A100 3,098 35,000 SH   SOLE   35,000 0 0
T Mobile Us Inc COM 872590104 246,867 3,822,056 SH   SOLE   3,822,056 0 0
T Mobile Us Inc COM 872590104 4,844 75,000 SH Call SOLE   75,000 0 0
Take-Two Interactive Softwar COM 874054109 34,222 577,400 SH   SOLE   577,400 0 0
Target Corp COM 87612E106 24,951 452,100 SH   SOLE   452,100 0 0
Time Warner Inc COM NEW 887317303 132,495 1,356,000 SH   SOLE   1,356,000 0 0
Transportadora De Gas Sur SPON ADR B 893870204 43,057 3,027,896 SH   DFND 1 3,027,896 0 0
United Contl Hldgs Inc COM 910047109 855 12,100 SH   SOLE   12,100 0 0
United Rentals Inc COM 911363109 88,398 706,900 SH   SOLE   706,900 0 0
Universal Hlth Svcs Inc CL B 913903100 12,445 100,000 SH   SOLE   100,000 0 0
Verizon Communications Inc COM 92343V104 2,438 50,000 SH   SOLE   50,000 0 0
Versartis Inc COM 92529L102 1,781 83,417 SH   SOLE   83,417 0 0
Vertex Pharmaceuticals Inc COM 92532F100 60,427 552,600 SH   SOLE   552,600 0 0
Viacom Inc New CL B 92553P201 149,977 3,217,006 SH   SOLE   3,217,006 0 0
Visa Inc COM CL A 92826C839 3,528 39,700 SH   SOLE   39,700 0 0
Wells Fargo & Co New COM 949746101 295,304 5,305,500 SH   SOLE   5,305,500 0 0
Westlake Chem Corp COM 960413102 905 13,700 SH   SOLE   13,700 0 0
Williams Cos Inc Del COM 969457100 70,844 2,394,200 SH   SOLE   2,394,200 0 0
Ypf Sociedad Anonima SPON ADR CL D 984245100 18,380 757,013 SH   DFND 1 757,013 0 0