The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ALEXION PHARMACEUTICALS, INC COM 015351909 78,215 569,500 SH Call SOLE   569,500 0 0
EDITAS MEDICINE INC COM COM 28106W903 4,315 255,000 SH Call SOLE   255,000 0 0
GILEAD SCIENCES INC COM 375558903 38,045 500,000 SH Call SOLE   500,000 0 0
VERTEX PHARMACEUTICALS INC COM 92532F900 9,109 60,000 SH Call SOLE   60,000 0 0
ASCENDIS PHARMA A S SPONSORED ADR 04351P101 41,157 1,482,600 SH   SOLE   1,482,600 0 0
GALAPAGOS NV SPON ADR SPONSORED ADR 36315X101 44,267 578,505 SH   SOLE   578,505 0 0
ACHILLION PHARMACEUTICALS INC COM 00448Q201 3,410 742,835 SH   SOLE   742,835 0 0
ACLARIS THERAPEUTICS INC COM 00461U105 5,030 185,472 SH   SOLE   185,472 0 0
ADVERUM BIOTECHNOLOGIES INC COM 00773U108 2,186 874,447 SH   SOLE   874,447 0 0
AGIOS PHARMACEUTICALS INC COM 00847X104 1,199 23,300 SH   SOLE   23,300 0 0
ASSEMBLY BIOSCIENCES INC COM 045396108 60,776 2,943,164 SH   SOLE   2,943,164 0 0
BIOHAVEN PHARMACEUTICAL HLDG CO LTD COM G11196105 1,750 70,000 SH   SOLE   70,000 0 0
BRISTOL MYERS SQUIBB CO COM 110122108 951 17,060 SH   SOLE   17,060 0 0
CASCADIAN THERAPEUTICS INC COM 14740B606 11,145 3,000,000 SH   SOLE   3,000,000 0 0
CHEMOCENTRYX INC COM 16383L106 1,104 118,000 SH   SOLE   118,000 0 0
CLOVIS ONCOLOGY INC COM 189464100 936 10,000 SH   SOLE   10,000 0 0
CORVUS PHARMACEUTICALS INC COM 221015100 9,741 805,000 SH   SOLE   805,000 0 0
CYTOMX THERAPEUTICS INC COM 23284F105 12,322 794,969 SH   SOLE   794,969 0 0
DICERNA PHARMACEUTICALS INC COM 253031108 2,435 767,992 SH   SOLE   767,992 0 0
EDITAS MEDICINE INC COM COM 28106W103 12,033 717,107 SH   SOLE   717,107 0 0
FATE THERAPEUTICS INC COM 31189P102 8,220 2,537,026 SH   SOLE   2,537,026 0 0
FIBROGEN INC COM 31572Q808 51,210 1,585,457 SH   SOLE   1,585,457 0 0
IRONWOOD PHARMACEUTICALS INC COM 46333X108 70,869 3,753,635 SH   SOLE   3,753,635 0 0
KINDRED BIOSCIENCES INC COM 494577109 4,686 544,880 SH   SOLE   544,880 0 0
KURA ONCOLOGY INC COM COM 50127T109 18,913 2,033,622 SH   SOLE   2,033,622 0 0
ATYR PHARMA INC COM 002120103 7,795 2,292,659 SH   SOLE   2,292,659 0 0
NABRIVA THERAPEUTICS COM G63637105 2,775 264,773 SH   SOLE   264,773 0 0
MINERVA NEUROSCIENCES INC COM 603380106 1,981 223,802 SH   SOLE   223,802 0 0
OVASCIENCE INC COM 69014Q101 5,479 3,512,332 SH   SOLE   3,512,332 0 0
ARATANA THERAPEUTICS INC COM 03874P101 723 100,000 SH   SOLE   100,000 0 0
REGULUS THERAPEUTICS INC COM 75915K101 3,656 3,709,144 SH   SOLE   3,709,144 0 0
SEATTLE GENETICS INC COM 812578102 776 15,000 SH   SOLE   15,000 0 0
SANGAMO BIOSCIENCES INC COM 800677106 22,599 2,568,119 SH   SOLE   2,568,119 0 0
TOCAGEN INC COM 888846102 18,074 1,502,373 SH   SOLE   1,502,373 0 0
TETRAPHASE PHARMACEUTICALS INC COM 88165N105 4,516 633,400 SH   SOLE   633,400 0 0
ALNYLAM PHARMACEUTICALS INC COM 02043Q107 831 10,425 SH   SOLE   10,425 0 0