The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ACLARIS THERAPEUTICS INC COM 00461U105 2,606 100,960 SH   SOLE   100,960 0 0
ADVERUM BIOTECHNOLOGIES INC COM 00773U108 81 22,236 SH   SOLE   22,236 0 0
AETNA INC NEW COM 00817Y108 37,182 233,837 SH   SOLE   233,837 0 0
ALDER BIOPHARMACEUTICALS INC COM 014339105 79,340 6,476,766 SH   SOLE   6,476,766 0 0
AMEDISYS INC COM 023436108 15,873 283,648 SH   SOLE   283,648 0 0
AMICUS THERAPEUTICS INC COM 03152W109 166,069 11,012,561 SH   SOLE   11,012,561 0 0
ARRAY BIOPHARMA INC COM 04269X105 215,946 17,556,586 SH   SOLE   17,556,586 0 0
ARRAY BIOPHARMA INC NOTE 3.000% 6/0 04269XAA3 34,266 19,000,000 PRN   SOLE   19,000,000 0 0
ASTRAZENECA PLC SPONSORED ADR 046353108 76,105 2,246,300 SH   SOLE   2,246,300 0 0
ATARA BIOTHERAPEUTICS INC COM 046513107 47,825 2,889,710 SH   SOLE   2,889,710 0 0
ATYR PHARMA INC COM 002120103 9,528 1,886,792 SH   SOLE   1,886,792 0 0
AUDENTES THERAPEUTICS INC COM 05070R104 36,114 1,289,332 SH   SOLE   1,289,332 0 0
AURINIA PHARMACEUTICALS INC COM 05156V102 2,084 332,310 SH   SOLE   332,310 0 0
BOSTON SCIENTIFIC CORP COM 101137107 17,604 603,493 SH   SOLE   603,493 0 0
CASCADIAN THERAPEUTICS INC COM NEW 14740B606 8,057 1,969,969 SH   SOLE   1,969,969 0 0
CASTLIGHT HEALTH INC CL B 14862Q100 44 10,229 SH   SOLE   10,229 0 0
CATALENT INC COM 148806102 5,895 147,663 SH   SOLE   147,663 0 0
CENTENE CORP DEL COM 15135B101 39,153 404,600 SH   SOLE   404,600 0 0
CHIMERIX INC COM 16934W106 22,184 4,225,575 SH   SOLE   4,225,575 0 0
CLOVIS ONCOLOGY INC COM 189464100 82,121 996,610 SH   SOLE   996,610 0 0
CYMABAY THERAPEUTICS INC COM 23257D103 13,276 1,647,100 SH   SOLE   1,647,100 0 0
CYTOMX THERAPEUTICS INC COM 23284F105 6,946 382,271 SH   SOLE   382,271 0 0
DECIPHERA PHARMACEUTICALS IN COM 24344T101 11,957 722,880 SH   SOLE   722,880 0 0
DIPLOMAT PHARMACY INC COM 25456K101 19,823 957,155 SH   SOLE   957,155 0 0
EHEALTH INC COM 28238P109 31,956 1,337,623 SH   SOLE   1,337,623 0 0
ENDOLOGIX INC COM 29266S106 29,189 6,544,676 SH   SOLE   6,544,676 0 0
EPIZYME INC COM 29428V104 23,051 1,210,000 SH   SOLE   1,210,000 0 0
FATE THERAPEUTICS INC COM 31189P102 5,619 1,419,058 SH   SOLE   1,419,058 0 0
GLYCOMIMETICS INC COM 38000Q102 16,985 1,214,088 SH   SOLE   1,214,088 0 0
GW PHARMACEUTICALS PLC ADS 36197T103 34,358 338,536 SH   SOLE   338,536 0 0
HOLOGIC INC COM 436440101 734 20,000 SH   SOLE   20,000 0 0
ICU MED INC COM 44930G107 37,495 201,750 SH   SOLE   201,750 0 0
IMMUNOGEN INC COM 45253H101 61,670 8,061,497 SH   SOLE   8,061,497 0 0
INC RESH HLDGS INC CL A 45329R109 14,012 267,918 SH   SOLE   267,918 0 0
INSMED INC COM PAR $.01 457669307 62,159 1,991,646 SH   SOLE   1,991,646 0 0
INVITAE CORP COM 46185L103 19,792 2,112,240 SH   SOLE   2,112,240 0 0
IRHYTHM TECHNOLOGIES INC COM 450056106 28,640 552,041 SH   SOLE   552,041 0 0
JOUNCE THERAPEUTICS INC COM 481116101 14,888 955,598 SH   SOLE   955,598 0 0
LA JOLLA PHARMACEUTICAL CO COM PAR $.0001 2 503459604 25,157 723,330 SH   SOLE   723,330 0 0
LHC GROUP INC COM 50187A107 235 3,310 SH   SOLE   3,310 0 0
LIVANOVA PLC SHS G5509L101 44,312 632,488 SH   SOLE   632,488 0 0
MEDPACE HLDGS INC COM 58506Q109 15,939 499,640 SH   SOLE   499,640 0 0
MODEL N INC COM 607525102 12,542 838,914 SH   SOLE   838,914 0 0
MOLINA HEALTHCARE INC COM 60855R100 31,703 461,074 SH   SOLE   461,074 0 0
NEKTAR THERAPEUTICS COM 640268108 350 14,580 SH   SOLE   14,580 0 0
NEUROCRINE BIOSCIENCES INC COM 64125C109 407 6,640 SH   SOLE   6,640 0 0
NEURODERM LTD ORD SHS M74231107 2,985 76,729 SH   SOLE   76,729 0 0
NEWLINK GENETICS CORP COM 651511107 12,712 1,248,700 SH   SOLE   1,248,700 0 0
NIGHTSTAR THERAPEUTICS PLC ADR 65413A101 28,839 1,769,346 SH   SOLE   1,769,346 0 0
OVID THERAPEUTICS INC COM 690469101 3,771 451,182 SH   SOLE   451,182 0 0
OXFORD IMMUNOTEC GLOBAL PLC ORD SHS G6855A103 34,465 2,051,487 SH   SOLE   2,051,487 0 0
PENUMBRA INC COM 70975L107 51,066 565,511 SH   SOLE   565,511 0 0
PETIQ INC COM CL A 71639T106 6,682 246,743 SH   SOLE   246,743 0 0
PRA HEALTH SCIENCES INC COM 69354M108 30,621 402,014 SH   SOLE   402,014 0 0
PROQR THRAPEUTICS N V SHS EURO N71542109 7,774 1,602,975 SH   SOLE   1,602,975 0 0
PUMA BIOTECHNOLOGY INC COM 74587V107 108,570 906,642 SH   SOLE   906,642 0 0
REGENXBIO INC COM 75901B107 54,950 1,667,672 SH   SOLE   1,667,672 0 0
SEATTLE GENETICS INC COM 812578102 100,318 1,843,733 SH   SOLE   1,843,733 0 0
SHIRE PLC SPONSORED ADR 82481R106 208 1,360 SH   SOLE   1,360 0 0
SYROS PHARMACEUTICALS INC COM 87184Q107 9,442 641,419 SH   SOLE   641,419 0 0
TELEFLEX INC COM 879369106 7,589 31,365 SH   SOLE   31,365 0 0
UNITEDHEALTH GROUP INC COM 91324P102 356 1,820 SH   SOLE   1,820 0 0
VERTEX PHARMACEUTICALS INC COM 92532F100 28,737 189,008 SH   SOLE   189,008 0 0
WAVE LIFE SCIENCES LTD SHS Y95308105 49,323 2,267,707 SH   SOLE   2,267,707 0 0
XENCOR INC COM 98401F105 27,511 1,200,294 SH   SOLE   1,200,294 0 0