The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ABBOTT LABS COM 002824100 51,186 896,900 SH   SOLE   896,900 0 0
ACLARIS THERAPEUTICS INC COM 00461U105 2,639 107,020 SH   SOLE   107,020 0 0
ADVERUM BIOTECHNOLOGIES INC COM 00773U108 78 22,236 SH   SOLE   22,236 0 0
ALDER BIOPHARMACEUTICALS INC COM 014339105 74,491 6,505,766 SH   SOLE   6,505,766 0 0
ALIGN TECHNOLOGY INC COM 016255101 253 1,140 SH   SOLE   1,140 0 0
ALLSCRIPTS HEALTHCARE SOLUTN COM 01988P108 25,762 1,770,600 SH   SOLE   1,770,600 0 0
AMICUS THERAPEUTICS INC COM 03152W109 144,271 10,025,770 SH   SOLE   10,025,770 0 0
ANAPTYSBIO INC COM 032724106 23,150 229,850 SH   SOLE   229,850 0 0
ARGENX SE SPONSORED ADR 04016X101 12,628 200,000 SH   SOLE   200,000 0 0
ARRAY BIOPHARMA INC COM 04269X105 244,657 19,113,864 SH   SOLE   19,113,864 0 0
ARRAY BIOPHARMA INC NOTE 2.625%12/0 04269XAB1 21,578 19,000,000 PRN   SOLE   19,000,000 0 0
ASTRAZENECA PLC SPONSORED ADR 046353108 70,150 2,021,600 SH   SOLE   2,021,600 0 0
ATARA BIOTHERAPEUTICS INC COM 046513107 50,969 2,815,988 SH   SOLE   2,815,988 0 0
AUDENTES THERAPEUTICS INC COM 05070R104 29,041 929,326 SH   SOLE   929,326 0 0
BIOMARIN PHARMACEUTICAL INC COM 09061G101 223 2,500 SH   SOLE   2,500 0 0
BLUEBIRD BIO INC COM 09609G100 46,270 259,800 SH   SOLE   259,800 0 0
CASCADIAN THERAPEUTICS INC COM NEW 14740B606 2,403 649,446 SH   SOLE   649,446 0 0
CASTLIGHT HEALTH INC CL B 14862Q100 38 10,229 SH   SOLE   10,229 0 0
CATALENT INC COM 148806102 34,222 833,063 SH   SOLE   833,063 0 0
CELGENE CORP COM 151020104 68,147 653,000 SH   SOLE   653,000 0 0
CENTENE CORP DEL COM 15135B101 54,627 541,500 SH   SOLE   541,500 0 0
CHIMERIX INC COM 16934W106 17,746 3,832,778 SH   SOLE   3,832,778 0 0
CLOVIS ONCOLOGY INC COM 189464100 89,762 1,320,027 SH   SOLE   1,320,027 0 0
CYMABAY THERAPEUTICS INC COM 23257D103 18,421 2,002,265 SH   SOLE   2,002,265 0 0
CYTOMX THERAPEUTICS INC COM 23284F105 8,838 418,680 SH   SOLE   418,680 0 0
DECIPHERA PHARMACEUTICALS IN COM 24344T101 14,658 683,880 SH   SOLE   683,880 0 0
EHEALTH INC COM 28238P109 27,078 1,558,914 SH   SOLE   1,558,914 0 0
ENDOLOGIX INC COM 29266S106 31,715 5,928,101 SH   SOLE   5,928,101 0 0
EPIZYME INC COM 29428V104 24,167 1,925,689 SH   SOLE   1,925,689 0 0
FATE THERAPEUTICS INC COM 31189P102 33,394 5,465,486 SH   SOLE   5,465,486 0 0
GLOBUS MED INC CL A 379577208 8,573 208,600 SH   SOLE   208,600 0 0
GLYCOMIMETICS INC COM 38000Q102 32,416 1,930,668 SH   SOLE   1,930,668 0 0
HESKA CORP COM RESTRC NEW 42805E306 15,753 196,396 SH   SOLE   196,396 0 0
HORIZON PHARMA PLC SHS G4617B105 292 20,000 SH   SOLE   20,000 0 0
HUMANA INC COM 444859102 248 1,000 SH   SOLE   1,000 0 0
ICU MED INC COM 44930G107 30,234 139,972 SH   SOLE   139,972 0 0
IMMUNOGEN INC COM 45253H101 69,914 10,906,962 SH   SOLE   10,906,962 0 0
INC RESH HLDGS INC CL A 45329R109 46,535 1,067,318 SH   SOLE   1,067,318 0 0
INFLARX NV COM N44821101 17,960 857,300 SH   SOLE   857,300 0 0
INSMED INC COM PAR $.01 457669307 70,132 2,249,262 SH   SOLE   2,249,262 0 0
INVITAE CORP COM 46185L103 20,176 2,222,040 SH   SOLE   2,222,040 0 0
IRHYTHM TECHNOLOGIES INC COM 450056106 45,657 814,574 SH   SOLE   814,574 0 0
JOUNCE THERAPEUTICS INC COM 481116101 12,500 980,393 SH   SOLE   980,393 0 0
LIVANOVA PLC SHS G5509L101 49,198 615,588 SH   SOLE   615,588 0 0
MODEL N INC COM 607525102 13,446 853,714 SH   SOLE   853,714 0 0
NEKTAR THERAPEUTICS COM 640268108 318 5,327 SH   SOLE   5,327 0 0
NEWLINK GENETICS CORP COM 651511107 17,003 2,096,490 SH   SOLE   2,096,490 0 0
NIGHTSTAR THERAPEUTICS PLC ADR 65413A101 21,857 1,772,846 SH   SOLE   1,772,846 0 0
ODONATE THERAPEUTICS INC COM 676079106 14,923 596,900 SH   SOLE   596,900 0 0
OVID THERAPEUTICS INC COM 690469101 3,087 312,782 SH   SOLE   312,782 0 0
OXFORD IMMUNOTEC GLOBAL PLC ORD SHS G6855A103 32,388 2,318,387 SH   SOLE   2,318,387 0 0
PACIRA PHARMACEUTICALS INC COM 695127100 237 5,190 SH   SOLE   5,190 0 0
PENUMBRA INC COM 70975L107 58,086 617,279 SH   SOLE   617,279 0 0
PETIQ INC COM CL A 71639T106 4,900 224,343 SH   SOLE   224,343 0 0
PRA HEALTH SCIENCES INC COM 69354M108 22,823 250,614 SH   SOLE   250,614 0 0
PROQR THRAPEUTICS N V SHS EURO N71542109 5,026 1,558,392 SH   SOLE   1,558,392 0 0
PUMA BIOTECHNOLOGY INC COM 74587V107 90,307 913,573 SH   SOLE   913,573 0 0
REGENXBIO INC COM 75901B107 47,390 1,425,272 SH   SOLE   1,425,272 0 0
SEATTLE GENETICS INC COM 812578102 61,847 1,156,021 SH   SOLE   1,156,021 0 0
SYROS PHARMACEUTICALS INC COM 87184Q107 6,200 637,232 SH   SOLE   637,232 0 0
TELADOC INC COM 87918A105 5,228 150,000 SH   SOLE   150,000 0 0
TELEFLEX INC COM 879369106 42,918 172,486 SH   SOLE   172,486 0 0
TRANSENTERIX INC COM NEW 89366M201 9,684 5,017,790 SH   SOLE   5,017,790 0 0
UNITEDHEALTH GROUP INC COM 91324P102 32,765 148,620 SH   SOLE   148,620 0 0
UNIVERSAL HLTH SVCS INC CL B 913903100 24,608 217,100 SH   SOLE   217,100 0 0
VOCERA COMMUNICATIONS INC COM 92857F107 212 7,000 SH   SOLE   7,000 0 0
WAVE LIFE SCIENCES LTD SHS Y95308105 77,540 2,209,107 SH   SOLE   2,209,107 0 0
WELLCARE HEALTH PLANS INC COM 94946T106 29,030 144,349 SH   SOLE   144,349 0 0
XENCOR INC COM 98401F105 29,612 1,350,894 SH   SOLE   1,350,894 0 0