The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
58.Com Inc Adr SPON ADR REP A 31680Q104 59,188 741,142 SH   DFND 1 741,142 0 0
58.Com Inc Adr SPON ADR REP A 31680Q104 111,735 1,399,134 SH   SOLE 0 1,353,600 0 45,534
58.Com Inc Adr SPON ADR REP A 31680Q104 209,157 2,619,050 SH   DFND 2 2,102,322 0 516,728
ABIOMED COM 003654100 249,212 856,429 SH   DFND 2 628,771 0 227,658
ABIOMED COM 003654100 178,375 612,993 SH   DFND 1 612,993 0 0
ABIOMED COM 003654100 975 3,352 SH   DFND 3 3,352 0 0
ABIOMED COM 003654100 166,493 572,161 SH   SOLE 0 560,654 0 11,507
AJ Gallagher & Co COM 363576109 263,562 3,834,740 SH   DFND 2 3,086,446 0 748,294
AJ Gallagher & Co COM 363576109 81,698 1,188,675 SH   DFND 1 1,188,675 0 0
AJ Gallagher & Co COM 363576109 147,110 2,140,411 SH   SOLE 0 2,074,295 0 66,116
Acacia Reasearch Corp ACACIA TCH COM 003881307 503 143,640 SH   DFND 1 143,640 0 0
Acacia Reasearch Corp ACACIA TCH COM 003881307 778 222,180 SH   SOLE 0 222,180 0 0
Activision Blizzard Inc COM 00507V109 23,013 341,139 SH   DFND 1 341,139 0 0
Activision Blizzard Inc COM 00507V109 37,923 562,157 SH   DFND 2 310,701 0 251,456
Activision Blizzard Inc COM 00507V109 213 3,156 SH   DFND 3 3,156 0 0
Activision Blizzard Inc COM 00507V109 10,375 153,799 SH   SOLE 0 153,799 0 0
Adaptimmune Therapeutics ADR SPONDS ADR 00653A107 10,909 971,404 SH   DFND 1 971,404 0 0
Adaptimmune Therapeutics ADR SPONDS ADR 00653A107 11,060 984,825 SH   DFND 2 446,807 0 538,018
Adaptimmune Therapeutics ADR SPONDS ADR 00653A107 6,841 609,180 SH   SOLE 0 609,180 0 0
Aduro Biotechnology COM 00739L101 6,775 728,462 SH   DFND 1 728,462 0 0
Aduro Biotechnology COM 00739L101 6,610 710,757 SH   DFND 2 317,788 0 392,969
Aduro Biotechnology COM 00739L101 2,023 217,518 SH   SOLE 0 217,518 0 0
Advanced Micro Devices COM 007903107 23,262 2,314,619 SH   DFND 1 2,314,619 0 0
Advanced Micro Devices COM 007903107 79,570 7,917,418 SH   DFND 2 6,363,438 0 1,553,980
Advanced Micro Devices COM 007903107 43,385 4,316,908 SH   SOLE 0 4,179,199 0 137,709
Aerovironment COM 008073108 8,059 177,090 SH   DFND 1 177,090 0 0
Aerovironment COM 008073108 8,005 175,900 SH   SOLE 0 175,900 0 0
Aerovironment COM 008073108 7,580 166,565 SH   DFND 2 74,502 0 92,063
Agios Pharmaceuticals COM 00847X104 27,921 341,415 SH   DFND 1 341,415 0 0
Agios Pharmaceuticals COM 00847X104 261 3,196 SH   DFND 3 3,196 0 0
Agios Pharmaceuticals COM 00847X104 6,855 83,825 SH   DFND 2 2,339 0 81,486
Agios Pharmaceuticals COM 00847X104 12,570 153,705 SH   SOLE 0 153,705 0 0
Albemarle Corp COM 012653101 5,148 55,506 SH   DFND 1 55,506 0 0
Albemarle Corp COM 012653101 6,688 72,116 SH   DFND 2 72,116 0 0
Albemarle Corp COM 012653101 6,546 70,583 SH   SOLE 0 70,583 0 0
Alibaba Group Holding Sponsored ADR SPONSORED ADS 01609W102 1,708,432 9,308,225 SH   SOLE 0 7,753,802 0 1,554,423
Alibaba Group Holding Sponsored ADR SPONSORED ADS 01609W102 5,972,062 32,538,205 SH   DFND 2 12,892,642 0 19,645,563
Alibaba Group Holding Sponsored ADR SPONSORED ADS 01609W102 639,627 3,484,945 SH   DFND 1 3,484,945 0 0
Align Technology Inc COM 016255101 3,437 13,688 SH   DFND 2 13,688 0 0
Alnylam Pharmaceuticals COM 02043Q107 106,495 894,163 SH   DFND 1 894,163 0 0
Alnylam Pharmaceuticals COM 02043Q107 194,638 1,634,236 SH   DFND 2 1,146,181 0 488,055
Alnylam Pharmaceuticals COM 02043Q107 155,123 1,302,459 SH   SOLE 0 1,285,071 0 17,388
Alnylam Pharmaceuticals COM 02043Q107 400 3,355 SH   DFND 3 3,355 0 0
Alphabet Inc Class A CAP STK CL A 02079K305 13,647 13,158 SH   DFND 2 12,716 0 442
Alphabet Inc Class A CAP STK CL A 02079K305 23,371 22,534 SH   DFND 1 22,534 0 0
Alphabet Inc Class A CAP STK CL A 02079K305 82,295 79,348 SH   SOLE 0 79,348 0 0
Alphabet Inc Class C CAP STK CL C 02079K107 1,023 991 SH   DFND 3 991 0 0
Alphabet Inc Class C CAP STK CL C 02079K107 1,351,754 1,310,106 SH   DFND 2 708,094 0 602,012
Alphabet Inc Class C CAP STK CL C 02079K107 389,415 377,417 SH   DFND 1 377,417 0 0
Alphabet Inc Class C CAP STK CL C 02079K107 739,847 717,052 SH   SOLE 0 568,376 0 148,676
Amazon.Com COM 023135106 987,643 682,385 SH   DFND 1 682,385 0 0
Amazon.Com COM 023135106 4,947,835 3,418,571 SH   DFND 2 1,367,264 0 2,051,307
Amazon.Com COM 023135106 2,419 1,671 SH   DFND 3 1,671 0 0
Amazon.Com COM 023135106 2,520,839 1,741,705 SH   SOLE 0 1,464,400 0 277,305
Ambarella SHS G037AX101 4,301 87,800 SH   DFND 1 87,800 0 0
Ambarella SHS G037AX101 5,084 103,780 SH   DFND 2 46,626 0 57,154
Ambarella SHS G037AX101 3,601 73,505 SH   SOLE 0 73,505 0 0
Ameren COM 023608102 13,976 246,800 SH   DFND 1 246,800 0 0
Ameren COM 023608102 872 15,390 SH   DFND 2 15,390 0 0
American Express COM 025816109 36,267 388,793 SH   DFND 1 388,793 0 0
American Express COM 025816109 24,879 266,713 SH   DFND 2 180,626 0 86,087
American Express COM 025816109 302 3,238 SH   DFND 3 3,238 0 0
American Express COM 025816109 19,061 204,343 SH   SOLE 0 204,343 0 0
Analog Devices COM 032654105 13,130 144,085 SH   DFND 1 144,085 0 0
Analog Devices COM 032654105 15,382 168,787 SH   SOLE 0 168,787 0 0
Anthem Inc COM 036752103 313,861 1,428,590 SH   SOLE 0 1,382,624 0 45,966
Anthem Inc COM 036752103 169,351 770,828 SH   DFND 1 770,828 0 0
Anthem Inc COM 036752103 584,094 2,658,596 SH   DFND 2 2,132,749 0 525,847
Apache Corp COM 037411105 87,978 2,286,329 SH   DFND 1 2,286,329 0 0
Apache Corp COM 037411105 289,029 7,511,159 SH   DFND 2 6,049,086 0 1,462,073
Apache Corp COM 037411105 157,762 4,099,835 SH   SOLE 0 3,972,387 0 127,448
Apollo Senior Floating Rate COM 037636107 10,397 617,746 SH   DFND 1 617,746 0 0
Apple COM 037833100 9,373 55,867 SH   DFND 1 55,867 0 0
Apple COM 037833100 11,232 66,943 SH   SOLE 0 66,943 0 0
Atlassian Corp Plc CL A G06242104 52,525 974,129 SH   DFND 1 974,129 0 0
Atlassian Corp Plc CL A G06242104 112,559 2,087,514 SH   SOLE 0 1,128,761 0 958,753
Atlassian Corp Plc CL A G06242104 296,233 5,493,935 SH   DFND 2 2,146,002 0 3,347,933
Autohome Inc - ADR SP ADR RP CL A 05278C107 46,493 540,999 SH   DFND 1 540,999 0 0
Autohome Inc - ADR SP ADR RP CL A 05278C107 159,835 1,859,849 SH   DFND 2 1,483,430 0 376,419
Autohome Inc - ADR SP ADR RP CL A 05278C107 86,384 1,005,166 SH   SOLE 0 973,527 0 31,639
Avangrid COM 05351W103 16,844 329,500 SH   DFND 1 329,500 0 0
Avangrid COM 05351W103 1,141 22,320 SH   DFND 2 22,320 0 0
Baidu.com Sponsored ADR SPON ADR REP A 056752108 3,560,155 15,951,229 SH   DFND 2 6,013,823 0 9,937,406
Baidu.com Sponsored ADR SPON ADR REP A 056752108 303,039 1,357,763 SH   DFND 1 1,357,763 0 0
Baidu.com Sponsored ADR SPON ADR REP A 056752108 932,223 4,176,813 SH   SOLE 0 3,358,958 0 817,855
Banco Bradesco Pn ADR SP ADR PFD NEW 059460303 19,620 1,651,533 SH   DFND 1 1,651,533 0 0
Banco Bradesco Pn ADR SP ADR PFD NEW 059460303 166,473 14,012,891 SH   DFND 2 6,021,989 0 7,990,902
Baozun Spn Adr 1:1 SPONSORED ADR 06684L103 9,479 206,600 SH   DFND 1 206,600 0 0
Baozun Spn Adr 1:1 SPONSORED ADR 06684L103 12,830 279,634 SH   DFND 2 124,897 0 154,737
Baozun Spn Adr 1:1 SPONSORED ADR 06684L103 8,873 193,400 SH   SOLE 0 193,400 0 0
Beigene Ltd SPONSORED ADR 07725L102 3,539 21,067 SH   DFND 1 21,067 0 0
Beigene Ltd SPONSORED ADR 07725L102 11,147 66,350 SH   DFND 2 0 0 66,350
Benefitfocus Inc COM 08180D106 3,870 158,604 SH   DFND 2 70,982 0 87,622
Benefitfocus Inc COM 08180D106 2,840 116,400 SH   DFND 1 116,400 0 0
Benefitfocus Inc COM 08180D106 2,311 94,700 SH   SOLE 0 94,700 0 0
BlackRock Floating Rate Income COM 091941104 16,077 1,150,000 SH   DFND 1 1,150,000 0 0
Blackline COM 09239B109 4,610 117,573 SH   DFND 1 117,573 0 0
Blackline COM 09239B109 6,861 174,983 SH   DFND 2 77,649 0 97,334
Blackline COM 09239B109 4,032 102,835 SH   SOLE 0 102,835 0 0
Blackstone/GSO Strategic Credit Fund COM SHS BEN IN 09257R101 6,611 416,300 SH   DFND 1 416,300 0 0
Blackstone/GSO Strategic Credit Fund COM SHS BEN IN 09257R101 1,671 105,230 SH   DFND 2 105,230 0 0
Blue Capital Reinsurance Holdings Fund (USD) COM G1190F107 7,679 629,438 SH   DFND 1 629,438 0 0
Bluebird Bio Inc COM 09609G100 76,592 448,565 SH   DFND 1 448,565 0 0
Bluebird Bio Inc COM 09609G100 444,897 2,605,547 SH   DFND 2 1,059,439 0 1,546,108
Bluebird Bio Inc COM 09609G100 339,443 1,987,955 SH   SOLE 0 1,543,848 0 444,107
British Amer.Tobacco - ADR SPONSORED ADR 110448107 5,404 93,678 SH   DFND 1 93,678 0 0
British Amer.Tobacco - ADR SPONSORED ADR 110448107 1,737 30,117 SH   SOLE 0 30,117 0 0
CEVA Inc COM 157210105 4,314 119,170 SH   DFND 2 53,483 0 65,687
CEVA Inc COM 157210105 4,329 119,580 SH   DFND 1 119,580 0 0
CEVA Inc COM 157210105 2,986 82,500 SH   SOLE 0 82,500 0 0
CH Robinson Worldwide COM NEW 12541W209 85,009 907,151 SH   DFND 1 907,151 0 0
CH Robinson Worldwide COM NEW 12541W209 246,973 2,635,501 SH   DFND 2 2,143,991 0 491,510
CH Robinson Worldwide COM NEW 12541W209 146,588 1,564,272 SH   SOLE 0 1,521,335 0 42,937
CarMax Inc COM 143130102 3,662 59,116 SH   DFND 1 59,116 0 0
CarMax Inc COM 143130102 19,873 320,845 SH   DFND 2 320,845 0 0
CarMax Inc COM 143130102 4,481 72,338 SH   SOLE 0 72,338 0 0
Celgene COM 151020104 30,781 345,038 SH   DFND 1 345,038 0 0
Celgene COM 151020104 16,028 179,665 SH   SOLE 0 179,665 0 0
Celgene COM 151020104 258 2,889 SH   DFND 3 2,889 0 0
Celgene COM 151020104 26,274 294,524 SH   DFND 2 217,812 0 76,712
Cemex ADR SPON ADR NEW 151290889 32,689 4,937,915 SH   DFND 1 4,937,915 0 0
Cemex ADR SPON ADR NEW 151290889 168,737 25,488,965 SH   DFND 2 5,824,595 0 19,664,370
Cemex ADR SPON ADR NEW 151290889 8,443 1,275,421 SH   SOLE 0 1,275,421 0 0
Chegg COM 163092109 14,088 681,894 SH   DFND 2 185,741 0 496,153
Chegg COM 163092109 34,907 1,689,578 SH   DFND 1 1,689,578 0 0
Chegg COM 163092109 38,043 1,841,382 SH   SOLE 0 1,841,382 0 0
China Biologic Products Holdings Inc COM G21515104 58,977 728,116 SH   DFND 2 587,228 0 140,888
China Biologic Products Holdings Inc COM G21515104 17,072 210,762 SH   DFND 1 210,762 0 0
China Biologic Products Holdings Inc COM G21515104 32,354 399,436 SH   SOLE 0 386,622 0 12,814
China Rapid Finance ADR SPONSORED ADR 16953Q105 1,494 300,000 SH   SOLE 0 300,000 0 0
CoStar Group COM 22160N109 10,687 29,468 SH   DFND 2 821 0 28,647
CoStar Group COM 22160N109 397 1,096 SH   DFND 3 1,096 0 0
CoStar Group COM 22160N109 42,306 116,648 SH   DFND 1 116,648 0 0
CoStar Group COM 22160N109 19,015 52,429 SH   SOLE 0 52,429 0 0
Coca Cola COM 191216100 16,312 375,592 SH   DFND 1 375,592 0 0
Coca Cola COM 191216100 19,736 454,435 SH   SOLE 0 454,435 0 0
Codexis COM 192005106 8,738 794,398 SH   DFND 1 794,398 0 0
Codexis COM 192005106 9,998 908,946 SH   DFND 2 408,915 0 500,031
Codexis COM 192005106 6,596 599,635 SH   SOLE 0 599,635 0 0
Consolidated Edison COM 209115104 13,670 175,390 SH   DFND 1 175,390 0 0
Consolidated Edison COM 209115104 825 10,582 SH   DFND 2 10,582 0 0
Copa Holdings S A CL A P31076105 8,481 65,936 SH   DFND 1 65,936 0 0
Copa Holdings S A CL A P31076105 240,532 1,869,952 SH   DFND 2 1,130,882 0 739,070
Copa Holdings S A CL A P31076105 25,535 198,519 SH   SOLE 0 198,519 0 0
Credicorp COM G2519Y108 348 1,531 SH   DFND 1 1,531 0 0
Credicorp COM G2519Y108 247,686 1,090,934 SH   DFND 2 649,904 0 441,030
Credicorp COM G2519Y108 26,449 116,497 SH   SOLE 0 116,497 0 0
Ctrip.com Intl Sponsored ADR AMERICAN DEP SHS 22943F100 180,992 3,882,280 SH   DFND 1 3,882,280 0 0
Ctrip.com Intl Sponsored ADR AMERICAN DEP SHS 22943F100 1,813,611 38,901,997 SH   DFND 2 16,233,308 0 22,668,689
Ctrip.com Intl Sponsored ADR AMERICAN DEP SHS 22943F100 553,774 11,878,456 SH   SOLE 0 9,568,827 0 2,309,629
Denali Therapeutics COM 24823R105 6,585 334,428 SH   DFND 2 9,001 0 325,427
Denali Therapeutics COM 24823R105 26,280 1,334,666 SH   DFND 1 1,334,666 0 0
Denali Therapeutics COM 24823R105 241 12,263 SH   DFND 3 12,263 0 0
Denali Therapeutics COM 24823R105 69,141 3,511,489 SH   SOLE 0 3,511,489 0 0
Dexcom Inc COM 252131107 253,976 3,424,699 SH   DFND 2 1,356,688 0 2,068,011
Dexcom Inc COM 252131107 49,839 672,046 SH   DFND 1 672,046 0 0
Dexcom Inc COM 252131107 97,971 1,321,079 SH   SOLE 0 742,548 0 578,531
Digimarc COM 25381B101 2,227 93,000 SH   DFND 1 93,000 0 0
Digimarc COM 25381B101 5,676 236,975 SH   DFND 2 105,853 0 131,122
Digimarc COM 25381B101 1,952 81,500 SH   SOLE 0 81,500 0 0
Dolby Laboratories 'A' COM 25659T107 7,849 123,497 SH   DFND 1 123,497 0 0
Dolby Laboratories 'A' COM 25659T107 9,599 151,019 SH   SOLE 0 151,019 0 0
Dropbox Inc Class A Common Stock CL A 26210C104 68,311 2,185,942 SH   SOLE 0 2,185,942 0 0
EOG Resources COM 26875P101 295,574 2,807,769 SH   DFND 2 2,291,234 0 516,535
EOG Resources COM 26875P101 83,277 791,078 SH   DFND 1 791,078 0 0
EOG Resources COM 26875P101 148,083 1,406,695 SH   SOLE 0 1,361,158 0 45,537
Eaton Vance Senior Income Trust SH BEN INT 27826S103 12,837 1,885,000 SH   DFND 1 1,885,000 0 0
Ecolab COM 278865100 840 6,128 SH   DFND 1 6,128 0 0
Ecolab COM 278865100 1,052 7,673 SH   DFND 2 7,673 0 0
Edison International COM 281020107 11,796 185,300 SH   DFND 1 185,300 0 0
Edison International COM 281020107 768 12,070 SH   DFND 2 12,070 0 0
Ellie Mae COM 28849P100 17,083 185,809 SH   DFND 2 36,557 0 149,252
Ellie Mae COM 28849P100 47,360 515,114 SH   DFND 1 515,114 0 0
Ellie Mae COM 28849P100 380 4,135 SH   DFND 3 4,135 0 0
Ellie Mae COM 28849P100 24,132 262,479 SH   SOLE 0 262,479 0 0
Embraer ADR SP ADR REP 4 COM 29082A107 6,533 251,259 SH   DFND 1 251,259 0 0
Embraer ADR SP ADR REP 4 COM 29082A107 75,736 2,912,908 SH   DFND 2 232,956 0 2,679,952
Estee Lauder 'A' COM 518439104 28,815 192,461 SH   DFND 2 192,461 0 0
Eversource Energy COM 30040W108 14,076 238,900 SH   DFND 1 238,900 0 0
Eversource Energy COM 30040W108 1,099 18,653 SH   DFND 2 18,653 0 0
Exact Sciences COM 30063P105 4,174 103,501 SH   DFND 1 103,501 0 0
Exact Sciences COM 30063P105 6,003 148,857 SH   DFND 2 66,378 0 82,479
Exact Sciences COM 30063P105 4,434 109,935 SH   SOLE 0 109,935 0 0
Exelon Corporation COM 30161N101 14,821 379,930 SH   DFND 1 379,930 0 0
Exelon Corporation COM 30161N101 945 24,215 SH   DFND 2 24,215 0 0
Facebook Cl.A CL A 30303M102 460,650 2,882,849 SH   DFND 1 2,882,849 0 0
Facebook Cl.A CL A 30303M102 1,799,889 11,264,088 SH   DFND 2 5,266,151 0 5,997,937
Facebook Cl.A CL A 30303M102 957 5,990 SH   DFND 3 5,990 0 0
Facebook Cl.A CL A 30303M102 962,409 6,022,960 SH   SOLE 0 4,391,396 0 1,631,564
Faro Technologies COM 311642102 3,866 66,200 SH   DFND 1 66,200 0 0
Faro Technologies COM 311642102 6,300 107,880 SH   SOLE 0 107,880 0 0
Faro Technologies COM 311642102 7,478 128,053 SH   DFND 2 57,444 0 70,609
Fastenal COM 311900104 13,357 244,676 SH   DFND 2 244,676 0 0
Fastenal COM 311900104 17,397 318,683 SH   DFND 1 318,683 0 0
Fastenal COM 311900104 21,248 389,233 SH   SOLE 0 389,233 0 0
Ferrari NV COM N3167Y103 1,482,162 12,355,515 SH   DFND 2 3,955,114 0 8,400,401
Ferrari NV COM N3167Y103 274,314 2,286,725 SH   SOLE 0 2,286,725 0 0
Fiat Chrysler Automobiles SHS N31738102 102,863 5,068,426 SH   DFND 1 5,068,426 0 0
Fiat Chrysler Automobiles SHS N31738102 1,281,782 63,157,582 SH   DFND 2 31,555,322 0 31,602,260
Fiat Chrysler Automobiles SHS N31738102 182,468 8,990,781 SH   SOLE 0 8,695,199 0 295,582
Financial Engines COM 317485100 4,361 124,588 SH   DFND 1 124,588 0 0
Financial Engines COM 317485100 6,650 190,000 SH   SOLE 0 190,000 0 0
Financial Engines COM 317485100 9,081 259,454 SH   DFND 2 116,076 0 143,378
First Republic Bank COM 33616C100 152,846 1,650,430 SH   SOLE 0 1,612,890 0 37,540
First Republic Bank COM 33616C100 761 8,217 SH   DFND 3 8,217 0 0
First Republic Bank COM 33616C100 254,370 2,746,682 SH   DFND 2 2,109,011 0 637,671
First Republic Bank COM 33616C100 145,603 1,572,214 SH   DFND 1 1,572,214 0 0
First Trust Senior Floating Rate COM 33733U108 2,430 183,676 SH   DFND 1 183,676 0 0
Foamix Pharmaceuticals SHS M46135105 555 108,200 SH   DFND 1 108,200 0 0
Foamix Pharmaceuticals SHS M46135105 570 111,200 SH   SOLE 0 111,200 0 0
Fortive Corp COM 34959J108 365 4,714 SH   DFND 3 4,714 0 0
Fortive Corp COM 34959J108 21,974 283,456 SH   SOLE 0 283,456 0 0
Fortive Corp COM 34959J108 25,371 327,289 SH   DFND 2 201,368 0 125,921
Fortive Corp COM 34959J108 42,815 552,306 SH   DFND 1 552,306 0 0
Foundation Medicine COM 350465100 16,980 215,617 SH   DFND 2 96,335 0 119,282
Foundation Medicine COM 350465100 5,891 74,800 SH   DFND 1 74,800 0 0
Foundation Medicine COM 350465100 7,875 100,000 SH   SOLE 0 100,000 0 0
Glaukos Corp COM 377322102 20,025 649,530 SH   DFND 1 649,530 0 0
Glaukos Corp COM 377322102 5,451 176,795 SH   DFND 2 25,228 0 151,567
Glaukos Corp COM 377322102 181 5,884 SH   DFND 3 5,884 0 0
Glaukos Corp COM 377322102 8,861 287,404 SH   SOLE 0 287,404 0 0
Grubhub Inc COM 400110102 258,363 2,546,196 SH   DFND 1 2,546,196 0 0
Grubhub Inc COM 400110102 373,056 3,676,518 SH   DFND 2 2,541,240 0 1,135,278
Grubhub Inc COM 400110102 1,378 13,584 SH   DFND 3 13,584 0 0
Grubhub Inc COM 400110102 246,549 2,429,773 SH   SOLE 0 2,379,780 0 49,993
HDFC Bank ADR ADR REPS 3 SHS 40415F101 57,636 583,536 SH   DFND 2 470,557 0 112,979
HDFC Bank ADR ADR REPS 3 SHS 40415F101 74,363 752,887 SH   SOLE 0 752,887 0 0
HEICO COM 422806109 221 2,549 SH   DFND 3 2,549 0 0
HEICO COM 422806109 10,784 124,220 SH   DFND 1 124,220 0 0
HEICO COM 422806109 8,698 100,198 SH   SOLE 0 100,198 0 0
HEICO 'A' CL A 422806208 24,417 344,140 SH   DFND 2 247,129 0 97,011
HEICO 'A' CL A 422806208 15,776 222,351 SH   DFND 1 222,351 0 0
HEICO 'A' CL A 422806208 3,045 42,918 SH   SOLE 0 42,918 0 0
Himax Technologies Adr SPONSORED ADR 43289P106 4,163 675,800 SH   DFND 2 0 0 675,800
Howard Hughes COM 44267D107 37,562 269,977 SH   DFND 1 269,977 0 0
Howard Hughes COM 44267D107 127,393 915,641 SH   DFND 2 738,928 0 176,713
Howard Hughes COM 44267D107 69,754 501,361 SH   SOLE 0 484,733 0 16,628
Hutchison China Meditech SPONSORED ADR 44842L103 1,776 60,090 SH   DFND 1 60,090 0 0
Hutchison China Meditech SPONSORED ADR 44842L103 4,317 146,050 SH   DFND 2 0 0 146,050
ICICI Bank ADR ADR 45104G104 119,544 13,507,789 SH   DFND 2 11,365,116 0 2,142,673
ICICI Bank ADR ADR 45104G104 130,088 14,699,240 SH   SOLE 0 14,699,240 0 0
IPG Photonics Corp COM 44980X109 11,766 50,415 SH   DFND 1 50,415 0 0
IPG Photonics Corp COM 44980X109 22,711 97,314 SH   DFND 2 43,478 0 53,836
IPG Photonics Corp COM 44980X109 17,185 73,636 SH   SOLE 0 73,636 0 0
Illumina COM 452327109 385,611 1,631,043 SH   DFND 1 1,631,043 0 0
Illumina COM 452327109 1,263,509 5,344,342 SH   SOLE 0 4,161,543 0 1,182,799
Illumina COM 452327109 2,528,001 10,692,840 SH   DFND 2 3,376,814 0 7,316,026
Illumina COM 452327109 876 3,706 SH   DFND 3 3,706 0 0
Infosys Ltd ADR SPONSORED ADR 456788108 6,517 365,098 SH   DFND 1 365,098 0 0
Infosys Ltd ADR SPONSORED ADR 456788108 3,521 197,270 SH   DFND 2 186,923 0 10,347
Interactive Brokers Group COM 45841N107 101,522 1,509,852 SH   DFND 1 1,509,852 0 0
Interactive Brokers Group COM 45841N107 199,808 2,971,570 SH   DFND 2 2,332,900 0 638,670
Interactive Brokers Group COM 45841N107 112,772 1,677,153 SH   SOLE 0 1,636,567 0 40,586
Interactive Brokers Group COM 45841N107 476 7,073 SH   DFND 3 7,073 0 0
Intuitive Surgical COM NEW 46120E602 131,289 318,023 SH   DFND 1 318,023 0 0
Intuitive Surgical COM NEW 46120E602 722,151 1,749,270 SH   DFND 2 688,173 0 1,061,097
Intuitive Surgical COM NEW 46120E602 405,747 982,843 SH   SOLE 0 668,412 0 314,431
Invesco Senior Income Trust COM 46131H107 45,976 10,449,118 SH   DFND 1 10,449,118 0 0
Invesco Senior Income Trust COM 46131H107 2,657 603,800 SH   DFND 2 603,800 0 0
Ionis Pharmaceuticals COM 462222100 31,108 705,721 SH   DFND 1 705,721 0 0
Ionis Pharmaceuticals COM 462222100 68,306 1,549,594 SH   SOLE 0 826,814 0 722,780
Ionis Pharmaceuticals COM 462222100 176,643 4,007,336 SH   DFND 2 1,530,580 0 2,476,756
Itau Unibanco Holding SA-ADR SPON ADR REP PFD 465562106 19,089 1,223,628 SH   DFND 1 1,223,628 0 0
Itau Unibanco Holding SA-ADR SPON ADR REP PFD 465562106 368,395 23,615,078 SH   DFND 2 8,626,408 0 14,988,670
Itau Unibanco Holding SA-ADR SPON ADR REP PFD 465562106 20,727 1,328,635 SH   SOLE 0 1,328,635 0 0
JD.Com Inc - ADR SPON ADR CL A 47215P106 72,963 1,802,007 SH   DFND 1 1,802,007 0 0
JD.Com Inc - ADR SPON ADR CL A 47215P106 386,802 9,553,022 SH   DFND 2 4,967,022 0 4,586,000
JD.Com Inc - ADR SPON ADR CL A 47215P106 26,566 656,101 SH   SOLE 0 656,101 0 0
Jianpu Technology Inc- ADR ADR 47738D101 2,719 491,650 SH   DFND 1 491,650 0 0
Jianpu Technology Inc- ADR ADR 47738D101 2,893 523,192 SH   SOLE 0 523,192 0 0
Johnson & Johnson COM 478160104 15,530 121,190 SH   DFND 1 121,190 0 0
Johnson & Johnson COM 478160104 18,604 145,175 SH   SOLE 0 145,175 0 0
Kirby COM 497266106 38,647 502,239 SH   DFND 1 502,239 0 0
Kirby COM 497266106 130,784 1,699,591 SH   DFND 2 1,366,637 0 332,954
Kirby COM 497266106 69,581 904,241 SH   SOLE 0 873,449 0 30,792
Korea Electric Power ADR SPONSORED ADR 500631106 1,005 65,300 SH   DFND 2 65,300 0 0
LendingTree COM 52603B107 74,159 225,992 SH   DFND 1 225,992 0 0
LendingTree COM 52603B107 206,636 629,701 SH   DFND 2 450,065 0 179,636
LendingTree COM 52603B107 134,878 411,024 SH   SOLE 0 403,015 0 8,009
Leucadia National COM 527288104 48,678 2,141,566 SH   DFND 1 2,141,566 0 0
Leucadia National COM 527288104 169,761 7,468,568 SH   DFND 2 5,991,207 0 1,477,361
Leucadia National COM 527288104 93,828 4,127,925 SH   SOLE 0 3,998,183 0 129,742
Liberty Media Cop DEB 4.00011/1 530715AG6 8,459 12,682,000 SH   DFND 1 12,682,000 0 0
Liberty Media Cop DEB 4.00011/1 530715AG6 1,037 1,555,000 SH   DFND 2 1,555,000 0 0
Lincoln Electric Hdg. COM 533900106 31,070 345,409 SH   DFND 1 345,409 0 0
Lincoln Electric Hdg. COM 533900106 112,717 1,253,108 SH   DFND 2 1,019,273 0 233,835
Lincoln Electric Hdg. COM 533900106 56,668 629,993 SH   SOLE 0 609,332 0 20,661
Lindblad Expeditions Holdings COM 535219109 11,017 1,072,701 SH   SOLE 0 1,072,701 0 0
Line Corp Sponsored Adr SPONSORED ADR 53567X101 19,255 493,601 SH   DFND 2 11,050 0 482,551
Luxoft Holding ORD SHS CL A G57279104 3,969 96,930 SH   DFND 2 0 0 96,930
M&T Bank COM 55261F104 19,227 104,293 SH   DFND 2 104,293 0 0
MakeMyTrip SHS V5633W109 88,337 2,545,744 SH   DFND 2 1,908,779 0 636,965
Markel Corp COM 570535104 129,416 110,588 SH   DFND 1 110,588 0 0
Markel Corp COM 570535104 332,970 284,529 SH   DFND 2 226,609 0 57,920
Markel Corp COM 570535104 374 320 SH   DFND 3 320 0 0
Markel Corp COM 570535104 174,358 148,992 SH   SOLE 0 144,696 0 4,296
MarketAxess Holdings COM 57060D108 1,129 5,193 SH   DFND 3 5,193 0 0
MarketAxess Holdings COM 57060D108 321,518 1,478,651 SH   DFND 2 1,057,953 0 420,698
MarketAxess Holdings COM 57060D108 220,806 1,015,480 SH   DFND 1 1,015,480 0 0
MarketAxess Holdings COM 57060D108 252,609 1,161,742 SH   SOLE 0 1,143,665 0 18,077
Martin Marietta Materials COM 573284106 98,555 475,420 SH   DFND 1 475,420 0 0
Martin Marietta Materials COM 573284106 229,749 1,108,291 SH   DFND 2 877,982 0 230,309
Martin Marietta Materials COM 573284106 320 1,544 SH   DFND 3 1,544 0 0
Martin Marietta Materials COM 573284106 130,537 629,703 SH   SOLE 0 612,748 0 16,955
Mastercard Inc-Class A CL A 57636Q104 210,368 1,201,006 SH   DFND 1 1,201,006 0 0
Mastercard Inc-Class A CL A 57636Q104 276,895 1,580,810 SH   SOLE 0 1,537,682 0 43,128
Mastercard Inc-Class A CL A 57636Q104 500,554 2,857,696 SH   DFND 2 2,246,834 0 610,862
Mastercard Inc-Class A CL A 57636Q104 730 4,165 SH   DFND 3 4,165 0 0
McDonald's COM 580135101 10,642 68,053 SH   DFND 1 68,053 0 0
McDonald's COM 580135101 12,516 80,034 SH   SOLE 0 80,034 0 0
MercadoLibre COM 58733R102 60,830 170,684 SH   DFND 1 170,684 0 0
MercadoLibre COM 58733R102 1,737,058 4,874,038 SH   DFND 2 1,811,779 0 3,062,259
MercadoLibre COM 58733R102 89,970 252,448 SH   SOLE 0 252,448 0 0
Mettler-Toledo COM 592688105 46,901 81,562 SH   DFND 1 81,562 0 0
Mettler-Toledo COM 592688105 279,577 486,196 SH   DFND 2 365,160 0 121,036
Mettler-Toledo COM 592688105 974 1,694 SH   DFND 3 1,694 0 0
Mettler-Toledo COM 592688105 27,215 47,328 SH   SOLE 0 47,328 0 0
Microchip Technology COM 595017104 7,552 82,660 SH   DFND 2 82,660 0 0
Microsoft COM 594918104 12,912 141,474 SH   DFND 1 141,474 0 0
Microsoft COM 594918104 30,452 333,643 SH   DFND 2 333,643 0 0
Microsoft COM 594918104 15,387 168,592 SH   SOLE 0 168,592 0 0
Mindbody Cl A COM CL A 60255W105 5,020 129,053 SH   DFND 1 129,053 0 0
Mindbody Cl A COM CL A 60255W105 7,480 192,298 SH   DFND 2 85,997 0 106,301
Mindbody Cl A COM CL A 60255W105 3,697 95,028 SH   SOLE 0 95,028 0 0
Moody's Corp COM 615369105 167,545 1,038,717 SH   DFND 1 1,038,717 0 0
Moody's Corp COM 615369105 591,858 3,669,298 SH   DFND 2 2,961,978 0 707,320
Moody's Corp COM 615369105 308,745 1,914,104 SH   SOLE 0 1,851,233 0 62,871
Mulesoft Inc-A CL A 625207105 17,126 389,408 SH   DFND 1 389,408 0 0
Mulesoft Inc-A CL A 625207105 24,413 555,097 SH   DFND 2 316,352 0 238,745
Mulesoft Inc-A CL A 625207105 10,468 238,022 SH   SOLE 0 238,022 0 0
Myriad Genetics Inc COM 62855J104 45,884 1,552,765 SH   DFND 1 1,552,765 0 0
Myriad Genetics Inc COM 62855J104 155,417 5,259,454 SH   DFND 2 4,217,374 0 1,042,080
Myriad Genetics Inc COM 62855J104 81,284 2,750,744 SH   SOLE 0 2,659,102 0 91,642
NVIDIA COM 67066G104 288,518 1,245,815 SH   DFND 1 1,245,815 0 0
NVIDIA COM 67066G104 1,297,198 5,601,269 SH   DFND 2 2,658,338 0 2,942,931
NVIDIA COM 67066G104 423 1,825 SH   DFND 3 1,825 0 0
NVIDIA COM 67066G104 718,449 3,102,247 SH   SOLE 0 2,320,116 0 782,131
National Instruments Corp COM 636518102 12,785 252,816 SH   DFND 1 252,816 0 0
National Instruments Corp COM 636518102 8,002 158,236 SH   DFND 2 70,945 0 87,291
National Instruments Corp COM 636518102 16,211 320,557 SH   SOLE 0 320,557 0 0
NetEase.com ADR SPONSORED ADR 64110W102 115,125 410,589 SH   DFND 1 410,589 0 0
NetEase.com ADR SPONSORED ADR 64110W102 227,041 809,732 SH   SOLE 0 534,311 0 275,421
NetEase.com ADR SPONSORED ADR 64110W102 522,639 1,863,973 SH   DFND 2 894,457 0 969,516
Netflix Inc COM 64110L106 348,853 1,181,150 SH   DFND 1 1,181,150 0 0
Netflix Inc COM 64110L106 1,169,241 3,958,832 SH   DFND 2 1,813,214 0 2,145,618
Netflix Inc COM 64110L106 782,879 2,650,681 SH   SOLE 0 2,077,781 0 572,900
Netflix Inc COM 64110L106 1,210 4,097 SH   DFND 3 4,097 0 0
New Oriental Education & Technology Sponsored ADR SPON ADR 647581107 666,163 7,600,260 SH   DFND 2 2,622,919 0 4,977,341
New Relic COM 64829B100 29,262 394,798 SH   DFND 1 394,798 0 0
New Relic COM 64829B100 13,263 178,935 SH   SOLE 0 178,935 0 0
New Relic COM 64829B100 274 3,698 SH   DFND 3 3,698 0 0
New Relic COM 64829B100 7,351 99,177 SH   DFND 2 2,762 0 96,415
Novocure Ltd ORD SHS G6674U108 11,526 528,725 SH   DFND 2 117,496 0 411,229
Novocure Ltd ORD SHS G6674U108 31,480 1,444,040 SH   DFND 1 1,444,040 0 0
Novocure Ltd ORD SHS G6674U108 229 10,495 SH   DFND 3 10,495 0 0
Novocure Ltd ORD SHS G6674U108 16,707 766,379 SH   SOLE 0 766,379 0 0
Now Inc/DE COM 67011P100 66,435 6,500,463 SH   DFND 2 5,098,704 0 1,401,759
Now Inc/DE COM 67011P100 29,508 2,887,237 SH   DFND 1 2,887,237 0 0
Now Inc/DE COM 67011P100 122 11,977 SH   DFND 3 11,977 0 0
Now Inc/DE COM 67011P100 41,526 4,063,240 SH   SOLE 0 3,965,744 0 97,496
Nucana Plc ADR SPONSORED ADR 67022C106 7,362 389,120 SH   DFND 1 389,120 0 0
Nucana Plc ADR SPONSORED ADR 67022C106 4,768 252,000 SH   SOLE 0 252,000 0 0
Nuveen Credit Strategies Income Fund COM SHS 67073D102 2,384 300,200 SH   DFND 2 300,200 0 0
Nuveen Credit Strategies Income Fund COM SHS 67073D102 5,640 710,300 SH   DFND 1 710,300 0 0
Nuveen Senior Income Fund COM 67067Y104 12,543 1,915,000 SH   DFND 1 1,915,000 0 0
PG&E Corp COM 69331C108 703 16,009 SH   DFND 2 16,009 0 0
PG&E Corp COM 69331C108 10,051 228,800 SH   DFND 1 228,800 0 0
Pacira Pharmaceuticals COM 695127100 4,851 155,730 SH   DFND 1 155,730 0 0
Pacira Pharmaceuticals COM 695127100 7,924 254,367 SH   DFND 2 113,702 0 140,665
Pacira Pharmaceuticals COM 695127100 3,115 100,000 SH   SOLE 0 100,000 0 0
Penumbra Inc COM 70975L107 281 2,434 SH   DFND 3 2,434 0 0
Penumbra Inc COM 70975L107 13,355 115,479 SH   DFND 2 24,113 0 91,366
Penumbra Inc COM 70975L107 35,269 304,962 SH   DFND 1 304,962 0 0
Penumbra Inc COM 70975L107 18,368 158,828 SH   SOLE 0 158,828 0 0
Pepsico COM 713448108 11,183 102,456 SH   DFND 1 102,456 0 0
Pepsico COM 713448108 13,200 120,938 SH   SOLE 0 120,938 0 0
Petrobras Common ADR SPONSORED ADR 71654V408 19,966 1,412,054 SH   DFND 1 1,412,054 0 0
Petrobras Common ADR SPONSORED ADR 71654V408 162,014 11,457,872 SH   DFND 2 3,790,798 0 7,667,074
Pioneer Floating Rate Trust COM 72369J102 14,409 1,236,803 SH   DFND 1 1,236,803 0 0
PriceSmart COM 741511109 85,888 1,027,989 SH   DFND 2 800,122 0 227,867
PriceSmart COM 741511109 12,384 148,222 SH   SOLE 0 148,222 0 0
Procter & Gamble COM 742718109 12,844 162,003 SH   DFND 1 162,003 0 0
Procter & Gamble COM 742718109 15,733 198,446 SH   SOLE 0 198,446 0 0
RPM Inc. COM 749685103 6,628 139,043 SH   DFND 1 139,043 0 0
RPM Inc. COM 749685103 7,729 162,141 SH   SOLE 0 162,141 0 0
Redfin COM 75737F108 229 10,040 SH   DFND 3 10,040 0 0
Redfin COM 75737F108 8,235 360,723 SH   DFND 2 9,867 0 350,856
Redfin COM 75737F108 31,423 1,376,403 SH   DFND 1 1,376,403 0 0
Redfin COM 75737F108 14,864 651,093 SH   SOLE 0 651,093 0 0
Regeneron Pharmaceuticals COM 75886F107 1,894 5,500 SH   DFND 2 5,500 0 0
Resmed Inc COM 761152107 77,249 784,495 SH   DFND 1 784,495 0 0
Resmed Inc COM 761152107 261,605 2,656,693 SH   DFND 2 2,142,453 0 514,240
Resmed Inc COM 761152107 140,471 1,426,537 SH   SOLE 0 1,381,583 0 44,954
Restaurant Brands International COM 76131D103 162,960 2,865,470 SH   DFND 2 1,864,129 0 1,001,341
Restaurant Brands International COM 76131D103 19,126 336,312 SH   SOLE 0 336,312 0 0
Restorbio Inc COM 76133L103 2,371 247,500 SH   DFND 1 247,500 0 0
Restorbio Inc COM 76133L103 2,898 302,500 SH   SOLE 0 302,500 0 0
Rio Tinto Spn.Adr 1:1 SPONSORED ADR 767204100 3,639 70,626 SH   DFND 2 70,626 0 0
Ritchie Bros Auctioneers (USA) COM 767744105 36,339 1,154,714 SH   DFND 1 1,154,714 0 0
Ritchie Bros Auctioneers (USA) COM 767744105 180,233 5,727,131 SH   DFND 2 4,640,783 0 1,086,348
Ritchie Bros Auctioneers (USA) COM 767744105 65,583 2,083,992 SH   SOLE 0 2,016,100 0 67,892
Ritchie Bros. Auctioneers COM 767744105 51,397 1,636,141 SH   DFND 2 744,898 0 891,243
Ritchie Bros. Auctioneers COM 767744105 12,469 396,943 SH   SOLE 0 396,943 0 0
Royal Crbn.Cruises COM V7780T103 132,935 1,129,057 SH   DFND 1 1,129,057 0 0
Royal Crbn.Cruises COM V7780T103 449,305 3,816,074 SH   DFND 2 3,053,679 0 762,395
Royal Crbn.Cruises COM V7780T103 238,023 2,021,600 SH   SOLE 0 1,955,442 0 66,158
Ryanair ADR SPONSORED ADR NE 783513203 706,761 5,753,042 SH   DFND 2 4,159,842 0 1,593,200
Ryanair ADR SPONSORED ADR NE 783513203 6,219 50,626 SH   SOLE 0 50,626 0 0
SEA Ltd ADR ADR 81141R100 31,750 2,817,236 SH   DFND 2 171,467 0 2,645,769
SEA Ltd ADR ADR 81141R100 3,895 345,621 SH   DFND 1 345,621 0 0
SEA Ltd ADR ADR 81141R100 7,225 641,104 SH   SOLE 0 641,104 0 0
SINA Corp ORD G81477104 5,550 53,230 SH   DFND 1 53,230 0 0
SINA Corp ORD G81477104 38,567 369,877 SH   DFND 2 121,773 0 248,104
Salesforce.com COM 79466L302 80,557 692,662 SH   DFND 1 692,662 0 0
Salesforce.com COM 79466L302 449,761 3,867,251 SH   DFND 2 1,503,567 0 2,363,684
Salesforce.com COM 79466L302 172,872 1,486,434 SH   SOLE 0 799,667 0 686,767
Schlumberger COM 806857108 7,717 119,127 SH   DFND 2 119,127 0 0
Seattle Genetics COM 812578102 115,742 2,211,350 SH   DFND 1 2,211,350 0 0
Seattle Genetics COM 812578102 209,832 4,009,016 SH   SOLE 0 3,103,547 0 905,469
Seattle Genetics COM 812578102 92 1,767 SH   DFND 3 1,767 0 0
Seattle Genetics COM 812578102 442,293 8,450,386 SH   DFND 2 4,738,865 0 3,711,521
Sherwin-Williams Co COM 824348106 3,432 8,752 SH   DFND 1 8,752 0 0
Sherwin-Williams Co COM 824348106 9,598 24,478 SH   DFND 2 24,478 0 0
Sherwin-Williams Co COM 824348106 4,158 10,604 SH   SOLE 0 10,604 0 0
Shopify 'A' CL A 82509L107 358 2,873 SH   DFND 3 2,873 0 0
Shopify 'A' CL A 82509L107 112,163 900,256 SH   DFND 2 777,348 0 122,908
Shopify 'A' CL A 82509L107 39,768 319,193 SH   DFND 1 319,193 0 0
Shopify 'A' CL A 82509L107 20,299 162,929 SH   SOLE 0 162,929 0 0
Siteone Landscape Supply COM 82982L103 165,488 2,148,079 SH   DFND 2 1,724,861 0 423,218
Siteone Landscape Supply COM 82982L103 48,461 629,034 SH   DFND 1 629,034 0 0
Siteone Landscape Supply COM 82982L103 90,394 1,173,333 SH   SOLE 0 1,136,690 0 36,643
Sohu.com COM 83408W103 3,785 122,403 SH   DFND 1 122,403 0 0
Sohu.com COM 83408W103 17,052 551,485 SH   DFND 2 176,482 0 375,003
Solarcity Corp NOTE 1.625 11/0 83416TAC4 10,975 11,907,000 SH   DFND 1 11,907,000 0 0
Solarcity Corp NOTE 1.625 11/0 83416TAC4 47 51,000 SH   DFND 2 51,000 0 0
Splunk Inc COM 848637104 3,969 40,340 SH   DFND 1 40,340 0 0
Splunk Inc COM 848637104 5,656 57,484 SH   SOLE 0 57,484 0 0
Splunk Inc COM 848637104 10,706 108,810 SH   DFND 2 48,515 0 60,295
Staar Surgical COM PAR $0.01 852312305 6,131 414,235 SH   DFND 2 185,493 0 228,742
Staar Surgical COM PAR $0.01 852312305 5,057 341,690 SH   DFND 1 341,690 0 0
Staar Surgical COM PAR $0.01 852312305 4,678 316,050 SH   SOLE 0 316,050 0 0
Stericycle Inc COM 858912108 24,121 412,118 SH   DFND 1 412,118 0 0
Stericycle Inc COM 858912108 43,504 743,279 SH   SOLE 0 718,410 0 24,869
Stericycle Inc COM 858912108 82,718 1,413,259 SH   DFND 2 1,137,229 0 276,030
Stitch Fix COM CL A 860897107 22,498 1,109,353 SH   DFND 1 1,109,353 0 0
Stitch Fix COM CL A 860897107 5,961 293,957 SH   DFND 2 7,887 0 286,070
Stitch Fix COM CL A 860897107 143 7,062 SH   DFND 3 7,062 0 0
Stitch Fix COM CL A 860897107 10,587 522,055 SH   SOLE 0 522,055 0 0
Stratasys SHS M85548101 4,567 226,300 SH   DFND 1 226,300 0 0
Stratasys SHS M85548101 2,918 144,600 SH   SOLE 0 144,600 0 0
Stratasys SHS M85548101 5,956 295,151 SH   DFND 2 132,264 0 162,887
Sunpower Corp DBCV 4.000 1/1 867652AL3 7,304 9,022,000 SH   DFND 1 9,022,000 0 0
Sunpower Corp DBCV 4.000 1/1 867652AL3 3,501 4,324,000 SH   DFND 2 4,324,000 0 0
TAL Education Group ADR ADS REPSTG COM 874080104 92,606 2,496,781 SH   DFND 1 2,496,781 0 0
TAL Education Group ADR ADS REPSTG COM 874080104 1,555,252 41,931,830 SH   DFND 2 11,209,282 0 30,722,548
TAL Education Group ADR ADS REPSTG COM 874080104 195,150 5,261,531 SH   SOLE 0 2,921,254 0 2,340,277
TD Ameritrade Holding Corp COM 87236Y108 116,607 1,968,709 SH   DFND 1 1,968,709 0 0
TD Ameritrade Holding Corp COM 87236Y108 272,001 4,592,278 SH   DFND 2 3,635,686 0 956,592
TD Ameritrade Holding Corp COM 87236Y108 428 7,219 SH   DFND 3 7,219 0 0
TD Ameritrade Holding Corp COM 87236Y108 151,969 2,565,739 SH   SOLE 0 2,498,196 0 67,543
TJX Companies COM 872540109 10,426 127,833 SH   DFND 1 127,833 0 0
TJX Companies COM 872540109 17,592 215,696 SH   DFND 2 215,696 0 0
TJX Companies COM 872540109 5,934 72,758 SH   SOLE 0 72,758 0 0
TSMC ADR SPONSORED ADR 874039100 236,960 5,414,986 SH   DFND 1 5,414,986 0 0
TSMC ADR SPONSORED ADR 874039100 1,309,800 29,931,441 SH   DFND 2 22,371,806 0 7,559,635
TSMC ADR SPONSORED ADR 874039100 387,942 8,865,212 SH   SOLE 0 8,564,282 0 300,930
Tableau Software Class A CL A 87336U105 43,744 541,251 SH   DFND 1 541,251 0 0
Tableau Software Class A CL A 87336U105 10,123 125,256 SH   DFND 2 3,910 0 121,346
Tableau Software Class A CL A 87336U105 375 4,643 SH   DFND 3 4,643 0 0
Tableau Software Class A CL A 87336U105 69,964 865,680 SH   SOLE 0 865,680 0 0
Teladoc COM 87918A105 7,210 178,910 SH   DFND 1 178,910 0 0
Teladoc COM 87918A105 4,715 117,000 SH   SOLE 0 117,000 0 0
Teladoc COM 87918A105 9,469 234,951 SH   DFND 2 105,138 0 129,813
Teradyne COM 880770102 247,670 5,418,300 SH   DFND 2 4,617,663 0 800,637
Teradyne COM 880770102 55,082 1,205,032 SH   DFND 1 1,205,032 0 0
Teradyne COM 880770102 98,686 2,158,957 SH   SOLE 0 2,089,145 0 69,812
TerraForm Power CL A COM 88104R100 17,231 1,605,857 SH   DFND 1 1,605,857 0 0
TerraForm Power CL A COM 88104R100 1,810 168,647 SH   DFND 2 168,647 0 0
Tesla Inc COM 88160R101 1,951,111 7,331,421 SH   DFND 2 2,677,873 0 4,653,548
Tesla Inc COM 88160R101 391,846 1,472,387 SH   DFND 1 1,472,387 0 0
Tesla Inc COM 88160R101 1,140 4,282 SH   DFND 3 4,282 0 0
Tesla Inc COM 88160R101 1,056,000 3,967,984 SH   SOLE 0 3,201,217 0 766,767
Thermo Fisher Scientific COM 883556102 77,447 375,117 SH   DFND 1 375,117 0 0
Thermo Fisher Scientific COM 883556102 271,670 1,315,846 SH   DFND 2 1,059,770 0 256,076
Thermo Fisher Scientific COM 883556102 146,996 711,984 SH   SOLE 0 689,515 0 22,469
Trupanion COM 898202106 8,259 276,305 SH   DFND 2 123,479 0 152,826
Trupanion COM 898202106 4,782 160,000 SH   DFND 1 160,000 0 0
Trupanion COM 898202106 21,969 735,000 SH   SOLE 0 735,000 0 0
Under Armour Inc Class A CL A 904311107 38,586 2,360,016 SH   DFND 1 2,360,016 0 0
Under Armour Inc Class A CL A 904311107 210,519 12,875,755 SH   DFND 2 4,961,598 0 7,914,157
Under Armour Inc Class A CL A 904311107 106,484 6,512,809 SH   SOLE 0 4,202,660 0 2,310,149
Under Armour Inc Class C CL C 904311206 21,734 1,514,542 SH   DFND 1 1,514,542 0 0
Under Armour Inc Class C CL C 904311206 12,824 893,642 SH   DFND 2 563,554 0 330,088
Under Armour Inc Class C CL C 904311206 11,241 783,334 SH   SOLE 0 783,334 0 0
Under Armour Inc Class C CL C 904311206 201 13,991 SH   DFND 3 13,991 0 0
United Parcel Service CL B 911312106 9,688 92,565 SH   DFND 1 92,565 0 0
United Parcel Service CL B 911312106 11,968 114,351 SH   SOLE 0 114,351 0 0
Vale SA ADR ADR 91912E105 3,062 240,728 SH   DFND 2 240,728 0 0
Varian Medical Systems Inc COM 92220P105 14,396 117,375 SH   DFND 2 117,375 0 0
Veeco Instruments COM 922417100 4,332 254,830 SH   DFND 1 254,830 0 0
Veeco Instruments COM 922417100 3,116 183,275 SH   DFND 2 82,243 0 101,032
Veeco Instruments COM 922417100 13,110 771,205 SH   SOLE 0 771,205 0 0
Verisk Analytics COM 92345Y106 70,506 677,938 SH   DFND 1 677,938 0 0
Verisk Analytics COM 92345Y106 259,048 2,490,850 SH   DFND 2 2,044,968 0 445,882
Verisk Analytics COM 92345Y106 128,805 1,238,514 SH   SOLE 0 1,199,595 0 38,919
Vertex Pharmaceuticals COM 92532F100 40,479 248,368 SH   DFND 1 248,368 0 0
Vertex Pharmaceuticals COM 92532F100 18,669 114,548 SH   SOLE 0 114,548 0 0
Vertex Pharmaceuticals COM 92532F100 382 2,345 SH   DFND 3 2,345 0 0
Vertex Pharmaceuticals COM 92532F100 29,570 181,434 SH   DFND 2 119,624 0 61,810
Visa Inc-Class A Shares COM CL A 92826C839 115,548 965,963 SH   DFND 1 965,963 0 0
Visa Inc-Class A Shares COM CL A 92826C839 214,160 1,790,336 SH   SOLE 0 1,731,374 0 58,962
Visa Inc-Class A Shares COM CL A 92826C839 403,255 3,371,131 SH   DFND 2 2,709,898 0 661,233
Voya Prime Rate Trust SH BEN INT 92913A100 44,002 8,445,676 SH   DFND 1 8,445,676 0 0
Voya Prime Rate Trust SH BEN INT 92913A100 2,029 389,450 SH   DFND 2 389,450 0 0
WEC Energy Group COM 92939U106 11,907 189,900 SH   DFND 1 189,900 0 0
WEC Energy Group COM 92939U106 891 14,207 SH   DFND 2 14,207 0 0
Wabtec COM 929740108 189,275 2,325,248 SH   DFND 2 1,808,364 0 516,884
Wabtec COM 929740108 84,633 1,039,718 SH   DFND 1 1,039,718 0 0
Wabtec COM 929740108 310 3,809 SH   DFND 3 3,809 0 0
Wabtec COM 929740108 107,646 1,322,432 SH   SOLE 0 1,285,251 0 37,181
Waters COM 941848103 78,687 396,111 SH   DFND 1 396,111 0 0
Waters COM 941848103 290,045 1,460,079 SH   DFND 2 1,198,376 0 261,703
Waters COM 941848103 142,506 717,372 SH   SOLE 0 694,523 0 22,849
Watsco Inc COM 942622200 39,470 218,103 SH   DFND 2 126,073 0 92,030
Watsco Inc COM 942622200 72,142 398,643 SH   DFND 1 398,643 0 0
Watsco Inc COM 942622200 628 3,470 SH   DFND 3 3,470 0 0
Watsco Inc COM 942622200 36,326 200,732 SH   SOLE 0 200,732 0 0
Wayfair Inc Class A CL A 94419L101 76,425 1,131,723 SH   DFND 1 1,131,723 0 0
Wayfair Inc Class A CL A 94419L101 38,991 577,391 SH   DFND 2 156,601 0 420,790
Wayfair Inc Class A CL A 94419L101 601 8,901 SH   DFND 3 8,901 0 0
Wayfair Inc Class A CL A 94419L101 43,694 647,034 SH   SOLE 0 647,034 0 0
Weibo Corp SPON ADR SPONSORED ADR 948596101 1,429 11,955 SH   DFND 1 11,955 0 0
Weibo Corp SPON ADR SPONSORED ADR 948596101 10,163 85,015 SH   DFND 2 29,136 0 55,879
Wipro Ltd ADR SPON ADR 1 SH 97651M109 139 27,017 SH   DFND 2 0 0 27,017
Wix Com SHS M98068105 219,846 2,763,621 SH   DFND 2 901,876 0 1,861,745
Workday Inc CL A 98138H101 85,719 674,370 SH   DFND 1 674,370 0 0
Workday Inc CL A 98138H101 476,440 3,748,248 SH   DFND 2 1,450,780 0 2,297,468
Workday Inc CL A 98138H101 314,499 2,474,224 SH   SOLE 0 1,810,705 0 663,519
Xylem COM 98419M100 1,745 22,689 SH   DFND 2 22,689 0 0
Xylem COM 98419M100 1,391 18,081 SH   DFND 1 18,081 0 0
Yandex SHS CLASS A N97284108 37,264 944,577 SH   DFND 1 944,577 0 0
Yandex SHS CLASS A N97284108 66,471 1,684,946 SH   SOLE 0 1,629,876 0 55,070
Yandex SHS CLASS A N97284108 118,635 3,007,218 SH   DFND 2 2,382,448 0 624,770
Zillow Group Inc Class A CL A 98954M101 9,864 182,670 SH   DFND 1 182,670 0 0
Zillow Group Inc Class A CL A 98954M101 39,634 733,959 SH   DFND 2 522,826 0 211,133
Zillow Group Inc Class A CL A 98954M101 24,189 447,953 SH   SOLE 0 435,134 0 12,819
Zillow Group Inc Class C CL C CAP STK 98954M200 46,467 863,708 SH   DFND 1 863,708 0 0
Zillow Group Inc Class C CL C CAP STK 98954M200 142,311 2,645,189 SH   DFND 2 2,020,990 0 624,199
Zillow Group Inc Class C CL C CAP STK 98954M200 76,054 1,413,649 SH   SOLE 0 1,373,605 0 40,044
iRobot COM 462726100 9,346 145,603 SH   DFND 1 145,603 0 0
iRobot COM 462726100 21,655 337,352 SH   SOLE 0 337,352 0 0
iRobot COM 462726100 11,086 172,705 SH   DFND 2 76,787 0 95,918