The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
MIRATI THERAPEUTICS INC COM 60468T905 25,574 348,900 SH Call SOLE   348,900 0 0
IRONWOOD PHARMACUTICALS INC COM 46333X908 14,675 1,084,600 SH Call SOLE   1,084,600 0 0
FIBROGEN INC COM 31572Q908 23,957 440,800 SH Call SOLE   440,800 0 0
FIBROGEN INC COM 31572Q958 54,350 1,000,000 SH Put SOLE   1,000,000 0 0
ASCENDIS PHARMA A S COM 04351P951 42,372 360,000 SH Put SOLE   360,000 0 0
ARBUTUS BIOPHARMA CORP COM 03879J100 7,779 2,172,883 SH   SOLE   2,172,883 0 0
ADURO BIOTECH INC COM 00739L101 7,719 1,939,390 SH   SOLE   1,939,390 0 0
AQUINOX PHARMACEUTICALS INC COM 03842B101 6,107 2,265,880 SH   SOLE   2,265,880 0 0
ARVINAS INC COM 04335A105 738 50,000 SH   SOLE   50,000 0 0
ASSEMBLY BIOSCIENCES INC COM 045396108 22,714 1,153,599 SH   SOLE   1,153,599 0 0
CHIASMA INC COM 16706W102 15,828 3,043,827 SH   SOLE   3,043,827 0 0
CURIS INC COM 231269200 5,935 2,982,208 SH   SOLE   2,982,208 0 0
CRISPR THERAPEUTICS AG COM H17182108 67,092 1,878,277 SH   SOLE   1,878,277 0 0
DICERNA PHARMACEUTICALS INC COM 253031108 48,585 3,316,407 SH   SOLE   3,316,407 0 0
EIGER BIOPHARMACEUTICALS INC COM 28249U105 22,307 1,595,643 SH   SOLE   1,595,643 0 0
FIBROGEN INC COM 31572Q808 9,152 168,382 SH   SOLE   168,382 0 0
GOSSAMER BIO INC COM 38341P102 16,731 772,096 SH   SOLE   772,096 0 0
HARPOON THERAPEUTICS INC COM 41358P106 12,656 1,336,423 SH   SOLE   1,336,423 0 0
IRONWOOD PHARMACEUTICALS INC COM 46333X108 59,494 4,397,168 SH   SOLE   4,397,168 0 0
KURA ONCOLOGY INC COM 50127T109 87,541 5,276,753 SH   SOLE   5,276,753 0 0
KEZAR LIFE SCIENCES INC COM 49372L100 15,194 856,471 SH   SOLE   856,471 0 0
MAGENTA THERAPEUTICS INC COM 55910K108 21,045 1,277,787 SH   SOLE   1,277,787 0 0
MERSANA THERAPEUTICS INC COM 59045L106 12,098 2,300,000 SH   SOLE   2,300,000 0 0
MIRATI THERAPEUTICS INC COM 60468T105 73,300 1,000,000 SH   SOLE   1,000,000 0 0
MYOKARDIA INC COM 62857M105 24,881 478,574 SH   SOLE   478,574 0 0
SPARK THERAPEUTICS INC COM 84652J103 60,243 529,000 SH   SOLE   529,000 0 0
PROTHENA CORP PLC COM G72800108 8,813 726,519 SH   SOLE   726,519 0 0
ULTRAGENYX PHARMACEUTICAL INC COM 90400D108 34,534 497,899 SH   SOLE   497,899 0 0
ROCKET PHARMACEUTICALS INC COM 77313F106 7,893 450,000 SH   SOLE   450,000 0 0
ARCUS BIOSCIENCES INC COM 03969F109 12,367 990,146 SH   SOLE   990,146 0 0
RUBIUS THERAPEUTICS INC COM 78116T103 11,697 646,228 SH   SOLE   646,228 0 0
RHYTHM PHARMACEUTICALS INC COM 76243J105 10,987 400,838 SH   SOLE   400,838 0 0
SIENNA BIOPHARMACEUTICALS INC COM 82622H108 1,856 800,000 SH   SOLE   800,000 0 0
SCHOLAR ROCK HOLDING CORP COM 80706P103 6,364 338,668 SH   SOLE   338,668 0 0
SURFACE ONCOLOGY INC COM 86877M209 10,797 2,263,488 SH   SOLE   2,263,488 0 0
UNITY BIOTECHNOLOGY INC COM 91381U101 7,353 906,614 SH   SOLE   906,614 0 0
VERICEL CORP COM 92346J108 2,294 131,001 SH   SOLE   131,001 0 0
XENCOR INC COM 98401F105 63,966 2,059,429 SH   SOLE   2,059,429 0 0
ARGENX SE SPONSORED ADR 04016X101 103,004 825,087 SH   SOLE   825,087 0 0
ASCENDIS PHARMA A S SPONSORED ADR 04351P101 42,468 360,819 SH   SOLE   360,819 0 0
ZAI LAB LTD SPONSORED ADR 98887Q104 2,317 78,519 SH   SOLE   78,519 0 0