The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ACLARIS THERAPEUTICS INC COM 00461U105 84 11,320 SH   SOLE   11,320 0 0
ADVERUM BIOTECHNOLOGIES INC COM 00773U108 70 22,236 SH   SOLE   22,236 0 0
ALDER BIOPHARMACEUTICALS INC COM 014339105 66,684 6,505,766 SH   SOLE   6,505,766 0 0
ALDER BIOPHARMACEUTICALS INC NOTE 2.500% 2/0 014339AA3 19,989 25,000,000 PRN   SOLE   25,000,000 0 0
ALLAKOS INC COM 01671P100 88,788 1,698,648 SH   SOLE   1,698,648 0 0
AMICUS THERAPEUTICS INC COM 03152W109 79,736 8,323,217 SH   SOLE   8,323,217 0 0
ANAPTYSBIO INC COM 032724106 23,223 364,050 SH   SOLE   364,050 0 0
ANTHEM INC COM 036752103 30,334 115,500 SH   SOLE   115,500 0 0
ARGENX SE SPONSORED ADR 04016X101 92,320 960,961 SH   SOLE   960,961 0 0
ARRAY BIOPHARMA INC COM 04269X105 234,543 16,459,128 SH   SOLE   16,459,128 0 0
ARRAY BIOPHARMA INC NOTE 2.625%12/0 04269XAB1 22,845 19,000,000 PRN   SOLE   19,000,000 0 0
ARVINAS INC COM 04335A105 1,751 136,300 SH   SOLE   136,300 0 0
ATARA BIOTHERAPEUTICS INC COM 046513107 153,364 4,414,617 SH   SOLE   4,414,617 0 0
ATRICURE INC COM 04963C209 9,180 300,000 SH   SOLE   300,000 0 0
AUDENTES THERAPEUTICS INC COM 05070R104 49,072 2,301,667 SH   SOLE   2,301,667 0 0
AXONICS MODULATION TECH INC COM 05465P101 9,066 600,000 SH   SOLE   600,000 0 0
BEIGENE LTD SPONSORED ADR 07725L102 5,667 40,400 SH   SOLE   40,400 0 0
BRISTOL MYERS SQUIBB CO COM 110122108 44,427 854,700 SH   SOLE   854,700 0 0
CASTLIGHT HEALTH INC CL B 14862Q100 22 10,229 SH   SOLE   10,229 0 0
CHIMERIX INC COM 16934W106 9,162 3,564,950 SH   SOLE   3,564,950 0 0
CIGNA CORP NEW COM 125523100 52,344 275,610 SH   SOLE   275,610 0 0
CLOVIS ONCOLOGY INC COM 189464100 72,927 4,060,529 SH   SOLE   4,060,529 0 0
CVS HEALTH CORP COM 126650100 25,055 382,400 SH   SOLE   382,400 0 0
CYMABAY THERAPEUTICS INC COM 23257D103 23,208 2,948,865 SH   SOLE   2,948,865 0 0
DECIPHERA PHARMACEUTICALS IN COM 24344T101 34,700 1,653,180 SH   SOLE   1,653,180 0 0
EHEALTH INC COM 28238P109 41,931 1,091,395 SH   SOLE   1,091,395 0 0
EIDOS THERAPEUTICS INC COM 28249H104 11,744 853,500 SH   SOLE   853,500 0 0
ENDOLOGIX INC COM 29266S106 575 800,477 SH   SOLE   800,477 0 0
EPIZYME INC COM 29428V104 40,886 6,637,278 SH   SOLE   6,637,278 0 0
ESTABLISHMENT LABS HLDGS INC COM G31249108 3,898 142,167 SH   SOLE   142,167 0 0
FATE THERAPEUTICS INC COM 31189P102 132,915 10,359,666 SH   SOLE   10,359,666 0 0
FLEXION THERAPEUTICS INC COM 33938J106 150 13,260 SH   SOLE   13,260 0 0
GLOBAL BLOOD THERAPEUTICS IN COM 37890U108 6,880 167,600 SH   SOLE   167,600 0 0
GLYCOMIMETICS INC COM 38000Q102 18,737 1,978,547 SH   SOLE   1,978,547 0 0
GRITSTONE ONCOLOGY INC COM 39868T105 35,058 2,269,136 SH   SOLE   2,269,136 0 0
GW PHARMACEUTICALS PLC ADS 36197T103 275 2,820 SH   SOLE   2,820 0 0
HESKA CORP COM RESTRC NEW 42805E306 17,023 197,713 SH   SOLE   197,713 0 0
ICU MED INC COM 44930G107 20,970 91,321 SH   SOLE   91,321 0 0
IMMUNOGEN INC COM 45253H101 52,246 10,884,607 SH   SOLE   10,884,607 0 0
INFLARX NV COM N44821101 74,027 2,035,400 SH   SOLE   2,035,400 0 0
INVITAE CORP COM 46185L103 5,811 525,375 SH   SOLE   525,375 0 0
IRHYTHM TECHNOLOGIES INC COM 450056106 272 3,910 SH   SOLE   3,910 0 0
JAZZ PHARMACEUTICALS PLC SHS USD G50871105 16,943 136,680 SH   SOLE   136,680 0 0
JOUNCE THERAPEUTICS INC COM 481116101 864 256,473 SH   SOLE   256,473 0 0
KRYSTAL BIOTECH INC COM 501147102 6,754 325,000 SH   SOLE   325,000 0 0
LHC GROUP INC COM 50187A107 394 4,200 SH   SOLE   4,200 0 0
LIVANOVA PLC SHS G5509L101 47,106 514,987 SH   SOLE   514,987 0 0
LOGICBIO THERAPEUTICS INC COM 54142F102 9,477 911,287 SH   SOLE   911,287 0 0
MEDTRONIC PLC SHS G5960L103 38,194 419,900 SH   SOLE   419,900 0 0
MORPHOSYS AG SPONSORED ADS 617760202 22,605 895,600 SH   SOLE   895,600 0 0
MYOKARDIA INC COM 62857M105 387 7,930 SH   SOLE   7,930 0 0
NIGHTSTAR THERAPEUTICS PLC ADR 65413A101 20,688 1,795,846 SH   SOLE   1,795,846 0 0
ODONATE THERAPEUTICS INC COM 676079106 6,434 456,951 SH   SOLE   456,951 0 0
OVID THERAPEUTICS INC COM 690469101 1,785 737,550 SH   SOLE   737,550 0 0
OXFORD IMMUNOTEC GLOBAL PLC ORD SHS G6855A103 28,468 2,227,507 SH   SOLE   2,227,507 0 0
PENUMBRA INC COM 70975L107 17,793 145,608 SH   SOLE   145,608 0 0
PRA HEALTH SCIENCES INC COM 69354M108 17,914 194,800 SH   SOLE   194,800 0 0
REGENXBIO INC COM 75901B107 56,831 1,354,742 SH   SOLE   1,354,742 0 0
REPLIGEN CORP COM 759916109 317 6,020 SH   SOLE   6,020 0 0
REPLIMUNE GROUP INC COM 76029N106 21,890 2,188,957 SH   SOLE   2,188,957 0 0
SAGE THERAPEUTICS INC COM 78667J108 283 2,950 SH   SOLE   2,950 0 0
SCHOLAR ROCK HLDG CORP COM 80706P103 40,460 1,761,407 SH   SOLE   1,761,407 0 0
SI BONE INC COM 825704109 13,388 640,900 SH   SOLE   640,900 0 0
STRONGBRIDGE BIOPHARMA PLC SHS USD G85347105 56 12,500 SH   SOLE   12,500 0 0
SYROS PHARMACEUTICALS INC COM 87184Q107 9,188 1,649,538 SH   SOLE   1,649,538 0 0
TANDEM DIABETES CARE INC COM NEW 875372203 39,479 1,039,750 SH   SOLE   1,039,750 0 0
TELADOC HEALTH INC COM 87918A105 9,696 195,600 SH   SOLE   195,600 0 0
TEVA PHARMACEUTICAL INDS LTD SPONSORED ADR 881624209 28,202 1,828,900 SH   SOLE   1,828,900 0 0
TRICIDA INC COM 89610F101 11,616 492,600 SH   SOLE   492,600 0 0
UNIQURE NV SHS N90064101 37,565 1,303,422 SH   SOLE   1,303,422 0 0
UNITEDHEALTH GROUP INC COM 91324P102 28,773 115,500 SH   SOLE   115,500 0 0
VAPOTHERM INC COM 922107107 24,878 1,247,025 SH   SOLE   1,247,025 0 0
VERICEL CORP COM 92346J108 291 16,720 SH   SOLE   16,720 0 0
VIKING THERAPEUTICS INC COM 92686J106 124 16,260 SH   SOLE   16,260 0 0
WAVE LIFE SCIENCES LTD SHS Y95308105 94,069 2,237,607 SH   SOLE   2,237,607 0 0
WRIGHT MED GROUP N V ORD SHS 0.03 PAR N96617118 69,065 2,537,300 SH   SOLE   2,537,300 0 0
XENCOR INC COM 98401F105 111,543 3,084,703 SH   SOLE   3,084,703 0 0
XERIS PHARMACEUTICALS INC COM 98422L107 41,015 2,412,641 SH   SOLE   2,412,641 0 0