The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ACLARIS THERAPEUTICS INC COM 00461U105 68 11,320 SH   SOLE   11,320 0 0
ADVERUM BIOTECHNOLOGIES INC COM 00773U108 117 22,236 SH   SOLE   22,236 0 0
ALDER BIOPHARMACEUTICALS INC NOTE 2.500% 2/0 014339AA3 23,865 25,000,000 PRN   SOLE   25,000,000 0 0
ALDER BIOPHARMACEUTICALS INC COM 014339105 112,543 8,244,896 SH   SOLE   8,244,896 0 0
ALIGN TECHNOLOGY INC COM 016255101 40,716 143,200 SH   SOLE   143,200 0 0
ALLAKOS INC COM 01671P100 74,294 1,834,410 SH   SOLE   1,834,410 0 0
AMICUS THERAPEUTICS INC COM 03152W109 266,778 19,616,062 SH   SOLE   19,616,062 0 0
ANAPTYSBIO INC COM 032724106 36,300 496,918 SH   SOLE   496,918 0 0
ANTHEM INC COM 036752103 50,709 176,700 SH   SOLE   176,700 0 0
ARGENX SE SPONSORED ADR 04016X101 127,220 1,019,061 SH   SOLE   1,019,061 0 0
ARRAY BIOPHARMA INC COM 04269X105 267,461 10,970,518 SH   SOLE   10,970,518 0 0
ARRAY BIOPHARMA INC NOTE 2.625%12/0 04269XAB1 33,290 19,000,000 PRN   SOLE   19,000,000 0 0
ARVINAS INC COM 04335A105 2,228 150,955 SH   SOLE   150,955 0 0
ATARA BIOTHERAPEUTICS INC COM 046513107 178,295 4,485,417 SH   SOLE   4,485,417 0 0
ATRICURE INC COM 04963C209 8,707 325,000 SH   SOLE   325,000 0 0
AUDENTES THERAPEUTICS INC COM 05070R104 106,730 2,735,267 SH   SOLE   2,735,267 0 0
AURINIA PHARMACEUTICALS INC COM 05156V102 2,101 323,265 SH   SOLE   323,265 0 0
AVEDRO INC COM 05355N109 1,534 125,000 SH   SOLE   125,000 0 0
AXONICS MODULATION TECH INC COM 05465P101 14,336 598,600 SH   SOLE   598,600 0 0
BEIGENE LTD SPONSORED ADR 07725L102 5,333 40,400 SH   SOLE   40,400 0 0
BIOGEN INC COM 09062X103 39,074 165,300 SH   SOLE   165,300 0 0
BRISTOL MYERS SQUIBB CO COM 110122108 76,322 1,599,700 SH   SOLE   1,599,700 0 0
CASTLIGHT HEALTH INC SAN FRAN COM STK COM 14862Q100 38 10,229 SH   SOLE   10,229 0 0
CELGENE CORP COM 151020104 50,538 535,700 SH   SOLE   535,700 0 0
CHIMERIX INC COM 16934W106 7,427 3,536,718 SH   SOLE   3,536,718 0 0
CIGNA CORP NEW COM 125523100 265 1,648 SH   SOLE   1,648 0 0
CLOVIS ONCOLOGY INC COM 189464100 113,277 4,563,929 SH   SOLE   4,563,929 0 0
CYMABAY THERAPEUTICS INC COM 23257D103 39,093 2,943,765 SH   SOLE   2,943,765 0 0
DECIPHERA PHARMACEUTICALS IN COM 24344T101 37,801 1,628,653 SH   SOLE   1,628,653 0 0
EHEALTH INC COM 28238P109 76,205 1,222,405 SH   SOLE   1,222,405 0 0
EIDOS THERAPEUTICS INC COM 28249H104 19,977 851,900 SH   SOLE   851,900 0 0
ENDOLOGIX INC COM 29266S304 521 78,756 SH   SOLE   78,756 0 0
EPIZYME INC COM 29428V104 95,329 7,694,020 SH   SOLE   7,694,020 0 0
ESTABLISHMENT LABS HLDGS INC COM G31249108 3,418 142,167 SH   SOLE   142,167 0 0
FATE THERAPEUTICS INC COM 31189P102 182,019 10,359,666 SH   SOLE   10,359,666 0 0
FLEXION THERAPEUTICS INC COM 33938J106 270 21,630 SH   SOLE   21,630 0 0
GLOBAL BLOOD THERAPEUTICS IN COM 37890U108 8,871 167,600 SH   SOLE   167,600 0 0
GLYCOMIMETICS INC COM 38000Q102 25,147 2,018,247 SH   SOLE   2,018,247 0 0
GOSSAMER BIO INC COM 38341P102 5,418 250,000 SH   SOLE   250,000 0 0
GRITSTONE ONCOLOGY INC COM 39868T105 31,305 2,353,735 SH   SOLE   2,353,735 0 0
GW PHARMACEUTICALS PLC ADS 36197T103 475 2,820 SH   SOLE   2,820 0 0
HESKA CORP COM RESTRC NEW 42805E306 19,238 226,013 SH   SOLE   226,013 0 0
ICU MED INC COM 44930G107 12,378 51,721 SH   SOLE   51,721 0 0
IMMUNOGEN INC COM 45253H101 35,403 13,063,767 SH   SOLE   13,063,767 0 0
INFLARX NV COM N44821101 82,482 2,182,638 SH   SOLE   2,182,638 0 0
INVITAE CORP COM 46185L103 32,183 1,374,175 SH   SOLE   1,374,175 0 0
JAZZ PHARMACEUTICALS PLC SHS USD G50871105 38,522 269,480 SH   SOLE   269,480 0 0
JOUNCE THERAPEUTICS INC COM 481116101 1,578 254,590 SH   SOLE   254,590 0 0
KRYSTAL BIOTECH INC COM 501147102 10,676 324,500 SH   SOLE   324,500 0 0
LHC GROUP INC COM 50187A107 240 2,166 SH   SOLE   2,166 0 0
LIVANOVA PLC SHS G5509L101 56,666 582,687 SH   SOLE   582,687 0 0
LOGICBIO THERAPEUTICS INC COM 54142F102 8,989 909,787 SH   SOLE   909,787 0 0
MORPHOSYS AG SPONSORED ADS 617760202 20,289 893,800 SH   SOLE   893,800 0 0
MYOKARDIA INC COM 62857M105 325 6,252 SH   SOLE   6,252 0 0
NEVRO CORP COM 64157F103 213 3,400 SH   SOLE   3,400 0 0
ODONATE THERAPEUTICS INC COM 676079106 10,557 477,464 SH   SOLE   477,464 0 0
OVID THERAPEUTICS INC COM 690469101 1,305 737,550 SH   SOLE   737,550 0 0
OXFORD IMMUNOTEC GLOBAL PLC ORD SHS G6855A103 34,485 2,001,467 SH   SOLE   2,001,467 0 0
PENUMBRA INC COM 70975L107 47,509 323,170 SH   SOLE   323,170 0 0
PRA HEALTH SCIENCES INC COM 69354M108 19,190 174,000 SH   SOLE   174,000 0 0
REGENXBIO INC COM 75901B107 81,400 1,420,342 SH   SOLE   1,420,342 0 0
REPLIMUNE GROUP INC COM 76029N106 33,674 2,212,456 SH   SOLE   2,212,456 0 0
SAGE THERAPEUTICS INC COM 78667J108 231 1,450 SH   SOLE   1,450 0 0
SCHOLAR ROCK HLDG CORP COM 80706P103 38,540 2,051,089 SH   SOLE   2,051,089 0 0
SHOCKWAVE MED INC COM 82489T104 10,041 300,000 SH   SOLE   300,000 0 0
SI BONE INC COM 825704109 10,150 538,730 SH   SOLE   538,730 0 0
SURGERY PARTNERS INC COM 86881A100 179 15,900 SH   SOLE   15,900 0 0
SYROS PHARMACEUTICALS INC COM 87184Q107 15,037 1,645,200 SH   SOLE   1,645,200 0 0
TANDEM DIABETES CARE INC COM NEW 875372203 54,352 855,932 SH   SOLE   855,932 0 0
TCR2 THERAPEUTICS INC COM 87808K106 28,686 1,807,256 SH   SOLE   1,807,256 0 0
TELADOC HEALTH INC COM 87918A105 24,458 439,900 SH   SOLE   439,900 0 0
TEVA PHARMACEUTICAL INDS LTD SPONSORED ADS 881624209 49,345 3,147,000 SH   SOLE   3,147,000 0 0
TRICIDA INC COM 89610F101 18,935 490,300 SH   SOLE   490,300 0 0
UNIQURE NV SHS N90064101 77,994 1,307,522 SH   SOLE   1,307,522 0 0
UNITEDHEALTH GROUP INC COM 91324P102 32,858 132,890 SH   SOLE   132,890 0 0
VAPOTHERM INC COM 922107107 18,930 1,011,316 SH   SOLE   1,011,316 0 0
VERICEL CORP COM 92346J108 293 16,720 SH   SOLE   16,720 0 0
VIKING THERAPEUTICS INC COM 92686J106 162 16,260 SH   SOLE   16,260 0 0
WAVE LIFE SCIENCES LTD SHS Y95308105 110,004 2,831,507 SH   SOLE   2,815,341 0 0
WRIGHT MED GROUP N V ORD SHS N96617118 90,390 2,874,100 SH   SOLE   2,874,100 0 0
XENCOR INC COM 98401F105 94,317 3,036,603 SH   SOLE   3,036,603 0 0
XERIS PHARMACEUTICALS INC COM 98422L107 30,126 3,000,641 SH   SOLE   3,000,641 0 0