The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete. | |||||||||||||||||
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UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 13F FORM 13F INFORMATION TABLE |
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| COLUMN 1 | COLUMN 2 | COLUMN 3 | COLUMN 4 | COLUMN 5 | COLUMN 6 | COLUMN 7 | COLUMN 8 | ||||
| VALUE | SHRS OR | SH/ | PUT/ | INVESTMENT | OTHER | VOTING AUTHORITY | |||||
| NAME OF ISSUER | TITLE OF CLASS | CUSIP | (x$1000) | PRN AMT | PRN | CALL | DISCRETION | MANAGER | SOLE | SHARED | NONE |
| Aclaris Therapeutics, Inc. | 00461U105 | 000Common | 1,779 | 1,647,214 | SH | SOLE | 1,647,214 | 0 | 0 | ||
| Agile Therapeutics, Inc. | 00847L100 | 000Common | 1,794 | 1,513,975 | SH | SOLE | 1,513,975 | 0 | 0 | ||
| Amyris, Inc | 03236M200 | 000Common | 30,906 | 6,492,823 | SH | SOLE | 6,492,823 | 0 | 0 | ||
| Apellis Pharmaceuticals, Inc. | 03753U106 | 000Common | 9,239 | 383,538 | SH | SOLE | 383,538 | 0 | 0 | ||
| Arrowhead Pharmaceuticals Inc | 04280A100 | 000Common | 61,484 | 2,181,820 | SH | SOLE | 2,181,820 | 0 | 0 | ||
| Ascendis Pharma A/S | 04351P101 | 000000ADR | 198,432 | 2,060,135 | SH | SOLE | 2,060,135 | 0 | 0 | ||
| Aurinia Pharmaceuticals Inc. | 05156V102 | 000Common | 25,388 | 4,754,358 | SH | SOLE | 4,754,358 | 0 | 0 | ||
| Avrobio Inc | 05455M100 | 000Common | 10,277 | 727,832 | SH | SOLE | 727,832 | 0 | 0 | ||
| Bellus Health Inc | 07987C204 | 000Common | 2,957 | 462,787 | SH | SOLE | 462,787 | 0 | 0 | ||
| BioPharmX Corporation | 09072X309 | 000Common | 61 | 182,681 | SH | SOLE | 182,681 | 0 | 0 | ||
| Chiasma Inc | 16706W102 | 000Common | 8,029 | 1,621,950 | SH | SOLE | 1,621,950 | 0 | 0 | ||
| Codexis, Inc | 192,005,106 | 000Common | 35,857 | 2,614,458 | SH | SOLE | 2,614,458 | 0 | 0 | ||
| Crinetics Pharmaceuticals Inc | 22663K107 | 000Common | 50,763 | 3,375,169 | SH | SOLE | 3,375,169 | 0 | 0 | ||
| Cymabay Therapeutics Inc | 23257D103 | 000Common | 11,033 | 2,154,934 | SH | SOLE | 2,154,934 | 0 | 0 | ||
| DBV Technologies S.A. | 23306J101 | 000000ADR | 2,322 | 269,995 | SH | SOLE | 269,995 | 0 | 0 | ||
| Dermira Inc | 24983L104 | 000Common | 4,473 | 700,000 | SH | SOLE | 700,000 | 0 | 0 | ||
| Eiger BioPharmaceuticals Inc | 28249U105 | 000Common | 18,360 | 1,791,257 | SH | SOLE | 1,791,257 | 0 | 0 | ||
| Galmed Pharmaceuticals Ltd | M47238106 | 000000SHS | 4,568 | 955,670 | SH | SOLE | 955,670 | 0 | 0 | ||
| Genocea Biosciences Inc | 372,427,401 | 000Common | 1,817 | 626,401 | SH | SOLE | 626,401 | 0 | 0 | ||
| Homology Medicines, Inc. | 438,083,107 | 000Common | 21,084 | 1,164,883 | SH | SOLE | 1,164,883 | 0 | 0 | ||
| IGM Biosciences Inc | 449,585,108 | 000Common | 10,539 | 593,756 | SH | SOLE | 593,756 | 0 | 0 | ||
| Insmed Inc | 457,669,307 | 000Common | 24,667 | 1,398,338 | SH | SOLE | 1,398,338 | 0 | 0 | ||
| Iovance Biotherapeutics, Inc. | 462,260,100 | 000Common | 18,903 | 1,038,600 | SH | SOLE | 1,038,600 | 0 | 0 | ||
| Kadmon Holdings Inc | 48283N106 | 000Common | 31,769 | 12,606,605 | SH | SOLE | 12,606,605 | 0 | 0 | ||
| Kala Pharmaceuticals, Inc. | 483,119,103 | 000Common | 3,969 | 1,043,020 | SH | SOLE | 1,043,020 | 0 | 0 | ||
| KalVista Pharmaceuticals Inc. | 483,497,103 | 000Common | 17,131 | 1,476,796 | SH | SOLE | 1,476,796 | 0 | 0 | ||
| Karuna Therapeutics Inc | 48576A100 | 000Common | 5,304 | 325,000 | SH | SOLE | 325,000 | 0 | 0 | ||
| Kiniksa Pharmaceuticals | G5269C101 | 000Common | 7,178 | 843,478 | SH | SOLE | 843,478 | 0 | 0 | ||
| Matinas Biopharma Hldgs Inc | 576,810,105 | 000Common | 4,299 | 6,818,181 | SH | SOLE | 6,818,181 | 0 | 0 | ||
| MEI Pharma Inc | 55279B202 | 000Common | 9,483 | 5,644,477 | SH | SOLE | 5,644,477 | 0 | 0 | ||
| Menlo Therapeutics Inc. | 586,858,102 | 000Common | 17,970 | 4,011,236 | SH | SOLE | 4,011,236 | 0 | 0 | ||
| Mirati Therapeutics Inc. | 60468T105 | 000Common | 18,157 | 233,045 | SH | SOLE | 233,045 | 0 | 0 | ||
| Nabriva Therapeutics AG | G63637105 | 000000SHS | 5,509 | 2,754,486 | SH | SOLE | 2,754,486 | 0 | 0 | ||
| Obseva SA | H5861P103 | 000Common | 7,806 | 937,147 | SH | SOLE | 937,147 | 0 | 0 | ||
| Orchard Therapeutics plc | 68570P101 | 000000ADS | 15,588 | 1,312,084 | SH | SOLE | 1,312,084 | 0 | 0 | ||
| Precision Biosciences Inc | 74019P108 | 000Common | 2,353 | 280,511 | SH | SOLE | 280,511 | 0 | 0 | ||
| Protagonist Therapeutics Inc | 74,365,999,999,999,952,808,246,028,644,420,442,620,040,422,002,646,244,868,226,444,446,460,068,240,402,488,062,244,626,064,464,202,066,266,622 | 000Common | 7,183 | 598,100 | SH | SOLE | 598,100 | 0 | 0 | ||
| Rocket Pharmaceuticals Inc | 77313F106 | 000Common | 9,165 | 786,712 | SH | SOLE | 786,712 | 0 | 0 | ||
| Selecta Biosciences Inc | 816,212,104 | 000Common | 956 | 546,054 | SH | SOLE | 546,054 | 0 | 0 | ||
| Sierra Oncology, Inc | 82640U107 | 000Common | 952 | 2,438,270 | SH | SOLE | 2,438,270 | 0 | 0 | ||
| Sinovac Biotech Ltd. | P8696W104 | 000000SHS | 38,173 | 5,900,000 | SH | SOLE | 5,900,000 | 0 | 0 | ||
| Soleno Therapeutics, Inc. | 834,203,200 | 000Common | 6,403 | 4,268,959 | SH | SOLE | 4,268,959 | 0 | 0 | ||
| Soleno Therapeutics, Inc. - Warrant | 834,203,135 | 00Warrant | 9 | 188,772 | SH | SOLE | 188,772 | 0 | 0 | ||
| Tricida, Inc. | 89610F101 | 000Common | 43,107 | 1,396,405 | SH | SOLE | 1,396,405 | 0 | 0 | ||
| Verona Pharma PLC | 925,050,106 | 000000ADS | 6,823 | 1,492,951 | SH | SOLE | 1,492,951 | 0 | 0 | ||
| Xenon Pharmaceuticals Inc | 98420N105 | 000Common | 12,663 | 1,405,476 | SH | SOLE | 1,405,476 | 0 | 0 | ||
| Zai Lab Limited | 98887Q104 | 000000ADR | 7,185 | 222,107 | SH | SOLE | 222,107 | 0 | 0 | ||
| Zogenix Inc | 98978L204 | 000Common | 4,204 | 105,000 | SH | SOLE | 105,000 | 0 | 0 | ||
| Zymeworks Inc | 98985W102 | 000Common | 40,757 | 1,643,422 | SH | SOLE | 1,643,422 | 0 | 0 | ||