The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete. | |||||||||||||||||
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UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 13F FORM 13F INFORMATION TABLE |
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| COLUMN 1 | COLUMN 2 | COLUMN 3 | COLUMN 4 | COLUMN 5 | COLUMN 6 | COLUMN 7 | COLUMN 8 | ||||
| VALUE | SHRS OR | SH/ | PUT/ | INVESTMENT | OTHER | VOTING AUTHORITY | |||||
| NAME OF ISSUER | TITLE OF CLASS | CUSIP | (x$1000) | PRN AMT | PRN | CALL | DISCRETION | MANAGER | SOLE | SHARED | NONE |
| Aclaris Therapeutics, Inc. | 00461U105 | 000Common | 3,113 | 1,647,214 | SH | SOLE | 1,647,214 | 0 | 0 | ||
| Agile Therapeutics, Inc. | 00847L100 | 000Common | 473 | 189,247 | SH | SOLE | 189,247 | 0 | 0 | ||
| Amyris, Inc | 03236M200 | 000Common | 20,059 | 6,491,580 | SH | SOLE | 6,491,580 | 0 | 0 | ||
| Apellis Pharmaceuticals, Inc. | 03753U106 | 000Common | 11,744 | 383,538 | SH | SOLE | 383,538 | 0 | 0 | ||
| Arrowhead Pharmaceuticals Inc | 04280A100 | 000Common | 42,776 | 674,376 | SH | SOLE | 674,376 | 0 | 0 | ||
| Ascendis Pharma A/S | 04351P101 | 000000ADR | 286,606 | 2,060,135 | SH | SOLE | 2,060,135 | 0 | 0 | ||
| Atricure Inc | 04963C209 | 000Common | 2,099 | 64,573 | SH | SOLE | 64,573 | 0 | 0 | ||
| Aurinia Pharmaceuticals Inc. | 05156V102 | 000Common | 110,852 | 5,471,458 | SH | SOLE | 5,471,458 | 0 | 0 | ||
| Avrobio Inc | 05455M100 | 000Common | 14,128 | 701,832 | SH | SOLE | 701,832 | 0 | 0 | ||
| Chiasma Inc | 16706W102 | 000Common | 6,310 | 1,272,156 | SH | SOLE | 1,272,156 | 0 | 0 | ||
| Codexis, Inc | 192,005,106 | 000Common | 29,327 | 1,834,099 | SH | SOLE | 1,834,099 | 0 | 0 | ||
| Collegium Pharmaceutical Inc | 19459J104 | 000Common | 4,353 | 211,529 | SH | SOLE | 211,529 | 0 | 0 | ||
| Constellation Pharmaceutical | 210,373,106 | 000Common | 34,778 | 738,235 | SH | SOLE | 738,235 | 0 | 0 | ||
| Crinetics Pharmaceuticals Inc | 22663K107 | 000Common | 84,683 | 3,375,169 | SH | SOLE | 3,375,169 | 0 | 0 | ||
| Cymabay Therapeutics Inc | 23257D103 | 000Common | 2,112 | 1,077,467 | SH | SOLE | 1,077,467 | 0 | 0 | ||
| DBV Technologies S.A. | 23306J101 | 000000ADR | 2,889 | 269,995 | SH | SOLE | 269,995 | 0 | 0 | ||
| Dermira Inc | 24983L104 | 000Common | 13,871 | 914,961 | SH | SOLE | 914,961 | 0 | 0 | ||
| Eiger BioPharmaceuticals Inc | 28249U105 | 000Common | 26,690 | 1,791,257 | SH | SOLE | 1,791,257 | 0 | 0 | ||
| Forty Seven Inc | 34983P104 | 000Common | 16,330 | 414,792 | SH | SOLE | 414,792 | 0 | 0 | ||
| Galmed Pharmaceuticals Ltd | M47238106 | 000000SHS | 5,524 | 955,670 | SH | SOLE | 955,670 | 0 | 0 | ||
| Genocea Biosciences Inc | 372,427,401 | 000Common | 1,297 | 626,401 | SH | SOLE | 626,401 | 0 | 0 | ||
| Homology Medicines, Inc. | 438,083,107 | 000Common | 12,576 | 607,555 | SH | SOLE | 607,555 | 0 | 0 | ||
| IGM Biosciences Inc | 449,585,108 | 000Common | 11,008 | 288,468 | SH | SOLE | 288,468 | 0 | 0 | ||
| Insmed Inc | 457,669,307 | 000Common | 28,859 | 1,208,495 | SH | SOLE | 1,208,495 | 0 | 0 | ||
| Iovance Biotherapeutics, Inc. | 462,260,100 | 000Common | 33,761 | 1,219,707 | SH | SOLE | 1,219,707 | 0 | 0 | ||
| Kadmon Holdings Inc | 48283N106 | 000Common | 63,104 | 13,930,134 | SH | SOLE | 13,930,134 | 0 | 0 | ||
| Kala Pharmaceuticals, Inc. | 483,119,103 | 000Common | 3,849 | 1,043,020 | SH | SOLE | 1,043,020 | 0 | 0 | ||
| KalVista Pharmaceuticals Inc. | 483,497,103 | 000Common | 26,302 | 1,476,796 | SH | SOLE | 1,476,796 | 0 | 0 | ||
| Karuna Therapeutics Inc | 48576A100 | 000Common | 5,599 | 74,320 | SH | SOLE | 74,320 | 0 | 0 | ||
| Kiniksa Pharmaceuticals | G5269C101 | 000Common | 9,329 | 843,478 | SH | SOLE | 843,478 | 0 | 0 | ||
| Matinas Biopharma Hldgs Inc | 576,810,105 | 000Common | 15,477 | 6,818,181 | SH | SOLE | 6,818,181 | 0 | 0 | ||
| MEI Pharma Inc | 55279B202 | 000Common | 25,208 | 10,164,328 | SH | SOLE | 10,164,328 | 0 | 0 | ||
| Menlo Therapeutics Inc. | 586,858,102 | 000Common | 18,612 | 4,011,236 | SH | SOLE | 4,011,236 | 0 | 0 | ||
| Mirati Therapeutics Inc. | 60468T105 | 000Common | 17,466 | 135,545 | SH | SOLE | 135,545 | 0 | 0 | ||
| Nabriva Therapeutics AG | G63637105 | 000000SHS | 3,636 | 2,754,486 | SH | SOLE | 2,754,486 | 0 | 0 | ||
| New Frontier Health Corp | G6461G106 | 000Common | 143,000 | 14,300,000 | SH | SOLE | 14,300,000 | 0 | 0 | ||
| Orchard Therapeutics plc | 68570P101 | 000000ADS | 18,041 | 1,312,084 | SH | SOLE | 1,312,084 | 0 | 0 | ||
| Precision Biosciences Inc | 74019P108 | 000Common | 1,948 | 140,255 | SH | SOLE | 140,255 | 0 | 0 | ||
| Rocket Pharmaceuticals Inc | 77313F106 | 000Common | 17,906 | 786,712 | SH | SOLE | 786,712 | 0 | 0 | ||
| Selecta Biosciences Inc | 816,212,104 | 000Common | 20,526 | 8,624,287 | SH | SOLE | 8,624,287 | 0 | 0 | ||
| Sierra Oncology, Inc | 82640U107 | 000Common | 835 | 2,438,270 | SH | SOLE | 2,438,270 | 0 | 0 | ||
| Sinovac Biotech Ltd. | P8696W104 | 000000SHS | 38,173 | 5,900,000 | SH | SOLE | 5,900,000 | 0 | 0 | ||
| Soleno Therapeutics, Inc. | 834,203,200 | 000Common | 6,377 | 2,168,959 | SH | SOLE | 2,168,959 | 0 | 0 | ||
| Tricida, Inc. | 89610F101 | 000Common | 28,831 | 763,936 | SH | SOLE | 763,936 | 0 | 0 | ||
| Verona Pharma PLC | 925,050,106 | 000000ADS | 8,584 | 1,492,951 | SH | SOLE | 1,492,951 | 0 | 0 | ||
| Xenon Pharmaceuticals Inc | 98420N105 | 000Common | 11,554 | 881,310 | SH | SOLE | 881,310 | 0 | 0 | ||
| Zai Lab Limited | 98887Q104 | 000000ADR | 9,237 | 222,107 | SH | SOLE | 222,107 | 0 | 0 | ||
| Zogenix Inc | 98978L204 | 000Common | 5,474 | 105,000 | SH | SOLE | 105,000 | 0 | 0 | ||
| Zymeworks Inc | 98985W102 | 000Common | 67,395 | 1,482,519 | SH | SOLE | 1,482,519 | 0 | 0 | ||