The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
DICERNA PHARMACEUTICALS INC COM 253031108 103,638 4,080,237 SH   SOLE   4,080,237 0 0
MARINUS PHARMACEUTICALS INC COM 56854Q101 14,540 5,724,235 SH   SOLE   5,724,235 0 0
REPLIMUNE GROUP INC COM 76029N106 53,741 2,162,598 SH   SOLE   2,162,598 0 0
SOLID BIOSCIENCES INC COM 83422E105 11,343 3,871,164 SH   SOLE   3,871,164 0 0
APTINYX INC COM 03836N103 23,179 5,558,425 SH   SOLE   5,558,425 0 0
SPRINGWORKS THERAPEUTICS INC COM 85205L107 305,815 7,281,307 SH   SOLE   7,281,307 0 0
DYNAVAX TECHNOLOGIES CORP. COM 268158201 96,646 10,895,773 SH   SOLE   10,895,773 0 0
CONSTELLATION PHARMACEUTICALS INC. COM 210373106 42,070 1,400,000 SH   SOLE   1,400,000 0 0
X4 PHARMACEUTICALS INC COM 98420X103 15,364 1,648,485 SH   SOLE   1,648,485 0 0
SAVARA INC COM 805111101 22,976 5,128,593 SH   SOLE   5,128,593 0 0
ARCUTIS BIOTHERAPEUTICS, INC. COM 03969K108 120,334 3,979,292 SH   SOLE   3,979,292 0 0
MERSANA THERAPEUTICS, INC. COM 59045L106 80,629 3,445,667 SH   SOLE   3,445,667 0 0
CRINETICS PHARMACEUTICALS, INC. COM 22663K107 18,771 1,071,428 SH   SOLE   1,071,428 0 0
SAGE THERAPEUTICS, INC. COM 78667J108 20,753 499,100 SH   SOLE   499,100 0 0
AEGLEA BIOTHERAPEUTICS, INC. COM 00773J103 24,975 2,700,000 SH   SOLE   2,700,000 0 0