The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
89BIO INC COM 282559103 2,570 105,478 SH   SOLE 105,478 0 0
ACCURAY INC COM 004397105 4,063 974,400 SH   SOLE 974,400 0 0
ADICET BIO INC COM 007002108 1,090 77,577 SH   SOLE 77,577 0 0
AERIE PHARMACEUTICALS INC COM 00771V108 3,897 288,440 SH   SOLE 288,440 0 0
AERIE PHARMACEUTICALS INC NOTE 1.500%10/0 00771VAB4 1,376 1,500,000 PRN   SOLE 1,500,000 0 0
AFFIMED NV COM N01045108 5,089 874,357 SH   SOLE 874,357 0 0
ALECTOR INC COM 014442107 1,929 127,500 SH   SOLE 127,500 0 0
ALPINE IMMUNE SCIENCES INC COM 02083G100 1,426 113,202 SH   SOLE 113,202 0 0
APELLIS PHARMACEUTICALS INC COM 03753U106 2,512 43,916 SH   SOLE 43,916 0 0
APPLIED GENETIC TECHNOL CORP COM 03820J100 3,695 903,429 SH   SOLE 903,429 0 0
ARCUS BIOSCIENCES INC COM 03969F109 1,288 49,600 SH   SOLE 49,600 0 0
ARENA PHARMACEUTICALS INC COM NEW 040047607 5,902 76,815 SH   SOLE 76,815 0 0
ASCENDIS PHARMA A S SPONSORED ADR 04351P101 3,875 23,237 SH   SOLE 23,237 0 0
ATHIRA PHARMA INC COM 04746L104 566 16,531 SH   SOLE 16,531 0 0
ATRICURE INC COM 04963C209 7,417 133,229 SH   SOLE 133,229 0 0
BIOHAVEN PHARMACEUTICALS HOLD COM G11196105 7,037 82,100 SH   SOLE 82,100 0 0
BIOTELEMETRY INC COM 090672106 375 5,200 SH   SOLE 5,200 0 0
BLUEBIRD BIO INC COM 09609G100 1,310 30,273 SH   SOLE 30,273 0 0
BLUEPRINT MEDICINES CORP COM 09627Y109 23,205 206,911 SH   SOLE 206,911 0 0
CARA THERAPEUTICS INC COM 140755109 3,956 261,442 SH   SOLE 261,442 0 0
CARDIOVASCULAR SYSTEMS INC COM 141619106 6,617 151,200 SH   SOLE 151,200 0 0
CASSAVA SCIENCES INC COM 14817C107 3,069 450,000 SH   SOLE 450,000 0 0
COMPUGEN LTD ORD M25722105 1,395 115,202 SH   SOLE 115,202 0 0
CONSTELLATION PHARMACEUTICAL COM 210373106 2,897 100,594 SH   SOLE 100,594 0 0
DEXCOM INC COM 252131107 7,815 21,138 SH   SOLE 21,138 0 0
DICERNA PHARMACEUTICALS INC COM 253031108 12,948 587,756 SH   SOLE 587,756 0 0
FATE THERAPEUTICS INC COM 31189P102 30,403 334,360 SH   SOLE 334,360 0 0
FS DEVELOPMENT CORP COM CL A 303020101 1,650 150,000 SH   SOLE 150,000 0 0
GALAPAGOS NV SPON ADR 36315X101 7,956 80,375 SH   SOLE 80,375 0 0
GENFIT S A ADS 372279109 549 114,341 SH   SOLE 114,341 0 0
HARPOON THERAPEUTICS INC COM 41358P106 1,414 85,119 SH   SOLE 85,119 0 0
HOOKIPA PHARMA INC COM 43906K100 2,773 250,000 SH   SOLE 250,000 0 0
IDEAYA BIOSCIENCES INC COM 45166A102 4,643 331,661 SH   SOLE 331,661 0 0
INOGEN INC COM 45780L104 670 15,000 SH   SOLE 15,000 0 0
ISHARES TR NASDAQ BIOTECH ETF 464287556 7,181 47,400 SH   SOLE 47,400 0 0
IVERIC BIO INC COM 46583P102 476 68,951 SH   SOLE 68,951 0 0
JOHNSON AND JOHNSON COM 478160104 1,479 9,400 SH   SOLE 9,400 0 0
KADMON HOLDINGS INC COM 48283N106 1,952 470,361 SH   SOLE 470,361 0 0
KARUNA THERAPEUTICS INC COM 48576A100 1,693 16,668 SH   SOLE 16,668 0 0
KINNATE BIOPHARMA INC COM 49705R105 2,710 68,121 SH   SOLE 68,121 0 0
KURA ONCOLOGY INC COM 50127T109 294 9,000 SH   SOLE 9,000 0 0
LARIMAR THERAPEUTICS INC COM 517125100 1,037 48,428 SH   SOLE 48,428 0 0
LINEAGE CELL THERAPEUTICS INC COM 53566P109 141 80,000 SH   SOLE 80,000 0 0
LIQUIDIA TECHNOLOGIES INC COM NEW 53635D202 1,696 575,000 SH   SOLE 575,000 0 0
LUMINEX CORP COM 55027E102 3,563 154,091 SH   SOLE 154,091 0 0
MADRIGAL PHARMACEUTICALS INC COM 558868105 734 6,600 SH   SOLE 6,600 0 0
MASIMO CORPORATION COM 574795100 805 3,000 SH   SOLE 3,000 0 0
MEI PHARMA INC COM NEW 55279B202 1,824 691,000 SH   SOLE 691,000 0 0
MEREO BIOPHARMA GROUP PLC ADS 589492107 2,392 668,148 SH   SOLE 668,148 0 0
MERSANA THERAPEUTICS INC COM 59045L106 1,311 49,263 SH   SOLE 49,263 0 0
MORPHIC HOLDING INC COM 61775R105 2,062 61,467 SH   SOLE 61,467 0 0
NATUS MEDICAL INC COM 639050103 1,715 85,575 SH   SOLE 85,575 0 0
NEUROCRINE BIOSCIENCES INC COM 64125C109 8,838 92,208 SH   SOLE 92,208 0 0
NEURONETICS INC COM 64131A105 4,930 443,717 SH   SOLE 443,717 0 0
NEXTCURE INC COM 65343E108 709 65,000 SH   SOLE 65,000 0 0
OTONOMY INC COM 68906L105 2,521 389,592 SH   SOLE 389,592 0 0
PANDION THERAPEUTICS INC COM 698340106 865 58,222 SH   SOLE 58,222 0 0
PHASEBIO PHARMACEUTICALS INC COM 717224109 1,077 320,542 SH   SOLE 320,542 0 0
PREVAIL THERAPEUTICS INC COM 74140Y101 1,730 75,000 SH   SOLE 75,000 0 0
PROQR THERAPEUTICS N V SHS EURO N71542109 5,197 1,237,400 SH   SOLE 1,237,400 0 0
RADIUS HEALTH INC COM NEW 750469207 393 22,000 SH   SOLE 22,000 0 0
RADIUS HEALTH INC NOTE 3.000% 9/0 750469AA6 3,586 4,000,000 PRN   SOLE 4,000,000 0 0
REVOLUTION MEDICINES INC COM 76155X100 891 22,500 SH   SOLE 22,500 0 0
SAGE THERAPEUTICS INC COM 78667J108 15,685 181,306 SH   SOLE 181,306 0 0
SCPHARMACEUTICALS INC COM 810648105 206 38,891 SH   SOLE 38,891 0 0
SCYNEXIS INC COM NEW 811292200 1,530 200,000 SH   SOLE 200,000 0 0
STEREOTAXIS INC COM NEW 85916J409 69,634 13,680,554 SH   SOLE 13,680,554 0 0
SUTRO BIOPHARMA INC COM 869367102 1,845 85,000 SH   SOLE 85,000 0 0
SYNDAX PHARMACEUTICALS INC COM 87164F105 222 10,000 SH   SOLE 10,000 0 0
TRANSLATE BIO INC COM 89374L104 4,154 225,393 SH   SOLE 225,393 0 0
VENUS CONCEPT INC COM 92332W105 2,595 1,500,000 SH   SOLE 1,500,000 0 0
VERONA PHARMA PLC SPONSORED ADS 925050106 1,131 161,507 SH   SOLE 161,507 0 0
VIKING THERAPEUTICS INC COM 92686J106 2,567 455,900 SH   SOLE 455,900 0 0
XENON PHARMACEUTICALS INC COM 98420N105 5,330 346,535 SH   SOLE 346,535 0 0