The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ABBOTT LABS COM 002824100 10,891 93,948 SH   SOLE   93,948 0 0
ABBVIE INC COM 00287Y109 10,025 89,000 SH   SOLE   89,000 0 0
ACCOLADE INC COM 00437E102 12,491 230,000 SH   SOLE   0 0 230,000
AEROVATE THERAPEUTICS INC COM 008064107 11,415 500,000 SH   SOLE   124,353 0 375,647
AGILENT TECHNOLOGIES INC COM 00846U101 21,610 146,200 SH   SOLE   5,200 0 141,000
AGILITI INC COM 00848J104 18,116 828,369 SH   SOLE   76,545 0 751,824
ALIGN TECHNOLOGY INC COM 016255101 15,535 25,425 SH   SOLE   6,525 0 18,900
ALIGNMENT HEALTHCARE INC COM 01625V104 19,771 845,987 SH   SOLE   93,801 0 752,186
ALIGOS THERAPEUTICS INC COM 01626L105 345 16,908 SH   SOLE   16,908 0 0
ALLOVIR INC COM 019818103 690 34,950 SH   SOLE   34,950 0 0
ALNYLAM PHARMACEUTICALS INC COM 02043Q107 13,196 77,846 SH   SOLE   8,396 0 69,450
ALPHA TEKNOVA INC COM 02080L102 3,774 159,060 SH   SOLE   13,449 0 145,611
AMGEN INC COM 031162100 3,206 13,153 SH   SOLE   13,153 0 0
AMICUS THERAPEUTICS INC COM 03152W109 20,161 2,091,404 SH   SOLE   69,425 0 2,021,979
ARCUS BIOSCIENCES INC COM 03969F109 18,515 674,260 SH   SOLE   27,300 0 646,960
ARCUTIS BIOTHERAPEUTICS INC COM 03969K108 20,707 758,763 SH   SOLE   25,230 0 733,533
ARENA PHARMACEUTICALS INC COM NEW 040047607 22,001 322,599 SH   SOLE   11,601 0 310,998
ARGENX SE SPONSORED ADR 04016X101 563 1,870 SH   SOLE   1,870 0 0
ARVINAS INC COM 04335A105 21,775 282,792 SH   SOLE   36,913 0 245,879
ASCENDIS PHARMA A/S SPONSORED ADR 04351P101 467 3,550 SH   SOLE   3,550 0 0
ATEA PHARMACEUTICALS INC COM 04683R106 11,575 538,884 SH   SOLE   538,884 0 0
ATRICURE INC COM 04963C209 29,873 376,567 SH   SOLE   30,362 0 346,205
AVEANNA HEALTHCARE HLDGS INC COM 05356F105 20,509 1,658,000 SH   SOLE   270,391 0 1,387,609
AXONICS INC COM 05465P101 23,376 368,650 SH   SOLE   33,650 0 335,000
BEIGENE LTD SPONSORED ADR 07725L102 2,059 6,000 SH   SOLE   6,000 0 0
BELLUS HEALTH INC NEW COM NEW 07987C204 3,897 1,252,940 SH   SOLE   127,853 0 1,125,087
BIOMARIN PHARMACEUTICAL INC COM 09061G101 6,068 72,722 SH   SOLE   7,590 0 65,132
BIOGEN INC COM 09062X103 6,729 19,432 SH   SOLE   19,432 0 0
BOLT BIOTHERAPEUTICS INC COM 097702104 3,961 256,187 SH   SOLE   16,138 0 240,049
BOSTON SCIENTIFIC CORP COM 101137107 4,959 115,976 SH   SOLE   115,976 0 0
BRIDGEBIO PHARMA INC COM 10806X102 19,864 325,850 SH   SOLE   13,350 0 312,500
BRIGHT HEALTH GROUP INC COM 10920V107 15,650 912,000 SH   SOLE   188,668 0 723,332
BRISTOL-MYERS SQUIBB CO COM 110122108 8,391 125,574 SH   SOLE   125,574 0 0
CIGNA CORP NEW COM 125523100 5,665 23,897 SH   SOLE   23,897 0 0
CATALENT INC COM 148806102 8,893 82,250 SH   SOLE   0 0 82,250
CENTENE CORP DEL COM 15135B101 11,229 153,975 SH   SOLE   60,400 0 93,575
CHARLES RIV LABS INTL INC COM 159864107 8,434 22,800 SH   SOLE   0 0 22,800
CHECKMATE PHARMACEUTICALS IN COM 162818108 3,229 541,766 SH   SOLE   541,766 0 0
CODEX DNA INC COM 192003101 11,359 516,306 SH   SOLE   105,241 0 411,065
COGENT BIOSCIENCES INC COM 19240Q201 219 27,000 SH   SOLE   27,000 0 0
CONVEY HLDG PARENT INC COM 21258C108 19,915 1,750,000 SH   SOLE   391,892 0 1,358,108
COOPER COS INC COM NEW 216648402 9,542 24,080 SH   SOLE   0 0 24,080
CRYOPORT INC COM PAR $0.001 229050307 2,034 32,234 SH   SOLE   32,234 0 0
CYTOSORBENTS CORP COM NEW 23283X206 1,847 244,660 SH   SOLE   244,660 0 0
DANAHER CORPORATION COM 235851102 4,502 16,775 SH   SOLE   16,775 0 0
DENALI THERAPEUTICS INC COM 24823R105 5,099 65,000 SH   SOLE   0 0 65,000
DENTSPLY SIRONA INC COM 24906P109 6,832 108,000 SH   SOLE   0 0 108,000
DEXCOM INC COM 252131107 11,225 26,288 SH   SOLE   9,075 0 17,213
DR REDDYS LABS LTD ADR 256135203 474 6,454 SH   SOLE   6,454 0 0
ESSA PHARMA INC COM NEW 29668H708 9,484 331,963 SH   SOLE   20,370 0 311,593
EVOLENT HEALTH INC CL A 30050B101 31,134 1,474,138 SH   SOLE   162,609 0 1,311,529
EXACT SCIENCES CORP COM 30063P105 7,272 58,500 SH   SOLE   0 0 58,500
EXELIXIS INC COM 30161Q104 7,623 418,370 SH   SOLE   36,690 0 381,680
FATE THERAPEUTICS INC COM 31189P102 12,758 147,000 SH   SOLE   0 0 147,000
FINCH THERAPEUTICS GROUP INC COM 31773D101 4,227 300,399 SH   SOLE   26,030 0 274,369
FREELINE THERAPEUTICS HLDGS SPONSORED ADS 35655L107 5,222 640,714 SH   SOLE   27,171 0 613,543
GENERATION BIO CO COM 37148K100 444 16,522 SH   SOLE   16,522 0 0
GENETRON HLDGS LTD ADS 37186H100 218 10,800 SH   SOLE   10,800 0 0
GILEAD SCIENCES INC COM 375558103 2,014 29,250 SH   SOLE   29,250 0 0
GUARDANT HEALTH INC COM 40131M109 8,965 72,186 SH   SOLE   6,270 0 65,916
HARPOON THERAPEUTICS INC COM 41358P106 8,055 580,759 SH   SOLE   27,125 0 553,634
HOLOGIC INC COM 436440101 6,425 96,300 SH   SOLE   0 0 96,300
ILLUMINA INC COM 452327109 1,874 3,960 SH   SOLE   3,960 0 0
INCYTE CORP COM 45337C102 691 8,210 SH   SOLE   8,210 0 0
INSMED INC COM PAR $.01 457669307 26,004 913,700 SH   SOLE   25,221 0 888,479
INSPIRE MED SYS INC COM 457730109 12,997 67,250 SH   SOLE   0 0 67,250
INSTIL BIO INC COM 45783C101 326 16,878 SH   SOLE   16,878 0 0
INSULET CORP COM 45784P101 9,540 34,754 SH   SOLE   0 0 34,754
INVITAE CORP COM 46185L103 13,855 410,763 SH   SOLE   0 0 410,763
IQVIA HLDGS INC COM 46266C105 727 3,000 SH   SOLE   3,000 0 0
ITEOS THERAPEUTICS INC COM 46565G104 198 7,700 SH   SOLE   7,700 0 0
JOHNSON & JOHNSON COM 478160104 11,944 72,500 SH   SOLE   72,500 0 0
LABORATORY CORP AMER HLDGS COM NEW 50540R409 9,575 34,712 SH   SOLE   0 0 34,712
LEGEND BIOTECH CORP SPONSORED ADS 52490G102 304 7,400 SH   SOLE   7,400 0 0
LILLY ELI & CO COM 532457108 8,496 37,015 SH   SOLE   37,015 0 0
MEI PHARMA INC COM NEW 55279B202 368 128,980 SH   SOLE   128,980 0 0
MERCK & CO INC COM 58933Y105 5,852 75,250 SH   SOLE   75,250 0 0
MIRATI THERAPEUTICS INC COM 60468T105 393 2,431 SH   SOLE   2,431 0 0
MODERNA INC COM 60770K107 2,972 12,650 SH   SOLE   12,650 0 0
MOLINA HEALTHCARE INC COM 60855R100 7,768 30,697 SH   SOLE   0 0 30,697
MONTE ROSA THERAPEUTICS INC COM 61225M102 2,943 129,633 SH   SOLE   11,028 0 118,605
NATERA INC COM 632307104 5,659 49,850 SH   SOLE   0 0 49,850
NEUROPACE INC COM 641288105 11,228 471,966 SH   SOLE   89,568 0 382,398
NKARTA INC COM 65487U108 13,011 410,580 SH   SOLE   85,580 0 325,000
NOVAVAX INC COM NEW 670002401 18,779 88,450 SH   SOLE   4,300 0 84,150
OAK STR HEALTH INC COM 67181A107 18,766 320,400 SH   SOLE   32,574 0 287,826
OLEMA PHARMACEUTICALS INC COM 68062P106 13,711 490,020 SH   SOLE   90,100 0 399,920
OLINK HLDG AB SPONSORED ADS 680710100 21,135 614,025 SH   SOLE   61,344 0 552,681
ONCORUS INC COM 68236R103 4,623 335,000 SH   SOLE   169,986 0 165,014
PTC THERAPEUTICS INC COM 69366J200 14,046 332,291 SH   SOLE   0 0 332,291
PFIZER INC COM 717081103 7,574 193,400 SH   SOLE   193,400 0 0
QUANTERIX CORP COM 74766Q101 7,871 134,186 SH   SOLE   7,381 0 126,805
R1 RCM INC COM 749397105 25,255 1,135,589 SH   SOLE   210,444 0 925,145
RAIN THERAPEUTICS INC COM 75082Q105 282 18,155 SH   SOLE   18,155 0 0
REGENERON PHARMACEUTICALS COM 75886F107 2,357 4,220 SH   SOLE   4,220 0 0
REPLIGEN CORP COM 759916109 20,919 104,793 SH   SOLE   0 0 104,793
REPARE THERAPEUTICS INC COM 760273102 12,851 412,150 SH   SOLE   79,650 0 332,500
RESMED INC COM 761152107 16,050 65,105 SH   SOLE   0 0 65,105
ROCKET PHARMACEUTICALS INC COM 77313F106 20,822 470,135 SH   SOLE   15,735 0 454,400
SEAGEN INC COM 81181C104 10,792 68,356 SH   SOLE   8,630 0 59,726
SHOCKWAVE MED INC COM 82489T104 5,312 28,000 SH   SOLE   0 0 28,000
STAAR SURGICAL CO COM PAR $0.01 852312305 6,558 43,000 SH   SOLE   0 0 43,000
STRYKER CORPORATION COM 863667101 3,558 13,700 SH   SOLE   13,700 0 0
SYNEOS HEALTH INC CL A 87166B102 24,270 271,206 SH   SOLE   61,556 0 209,650
TALARIS THERAPEUTICS INC COM 87410C104 10,445 711,000 SH   SOLE   177,810 0 533,190
TANDEM DIABETES CARE INC COM NEW 875372203 3,127 32,100 SH   SOLE   32,100 0 0
TELADOC HEALTH INC COM 87918A105 8,421 50,638 SH   SOLE   0 0 50,638
TELEFLEX INCORPORATED COM 879369106 31,889 79,368 SH   SOLE   0 0 79,368
TENET HEALTHCARE CORP COM NEW 88033G407 5,694 85,000 SH   SOLE   0 0 85,000
TG THERAPEUTICS INC COM 88322Q108 16,096 414,949 SH   SOLE   13,449 0 401,500
THERMO FISHER SCIENTIFIC INC COM 883556102 5,246 10,400 SH   SOLE   10,400 0 0
TREACE MED CONCEPTS INC COM 89455T109 7,526 240,765 SH   SOLE   62,181 0 178,584
TURNING POINT THERAPEUTICS I COM 90041T108 16,513 211,650 SH   SOLE   0 0 211,650
UNITEDHEALTH GROUP INC COM 91324P102 11,533 28,800 SH   SOLE   28,800 0 0
VERTEX PHARMACEUTICALS INC COM 92532F100 1,960 9,721 SH   SOLE   9,721 0 0
VIRACTA THERAPEUTICS INC COM 92765F108 4,488 395,739 SH   SOLE   37,982 0 357,757
VOR BIOPHARMA INC COM 929033108 7,559 405,324 SH   SOLE   16,339 0 388,985
ZAI LAB LTD ADR 98887Q104 1,044 5,900 SH   SOLE   5,900 0 0
ZIMMER BIOMET HOLDINGS INC COM 98956P102 14,249 88,600 SH   SOLE   0 0 88,600
HORIZON THERAPEUTICS PUB L SHS G46188101 15,987 170,725 SH   SOLE   49,475 0 121,250
ICON PLC SHS G4705A100 5,943 28,750 SH   SOLE   0 0 28,750
MEDTRONIC PLC SHS G5960L103 9,571 77,101 SH   SOLE   77,101 0 0
NOVOCURE LTD ORD SHS G6674U108 9,272 41,800 SH   SOLE   0 0 41,800
ORTHO CLINICAL DIAGNOSTICS H ORD SHS G6829J107 27,549 1,286,750 SH   SOLE   94,480 0 1,192,270
UNION ACQUISITION CORP II SHS G9402Q100 2,175 215,582 SH   SOLE   215,582 0 0
CRISPR THERAPEUTICS AG NAMEN AKT H17182108 529 3,270 SH   SOLE   3,270 0 0
AFFIMED N V COM N01045108 383 45,000 SH   SOLE   45,000 0 0