The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ABBVIE INC COM 00287Y109 174,016 1,613,200 SH   SOLE   1,613,200 0 0
AC IMMUNE SA SHS H00263105 11,673 1,739,600 SH   SOLE   1,739,600 0 0
ACADIA PHARMACEUTICALS INC COM 004225108 9,136 550,000 SH   SOLE   550,000 0 0
ACCELERON PHARMA INC COM 00434H108 6,024 35,000 SH   SOLE   35,000 0 0
ACCELERON PHARMA INC COM 00434H108 211,356 1,228,100 SH Call SOLE   1,228,100 0 0
ADICET BIO INC COM 007002108 18,970 2,419,600 SH   SOLE   2,419,600 0 0
ALNYLAM PHARMACEUTICALS INC COM 02043Q107 80,622 427,000 SH   SOLE   427,000 0 0
ALPHATEC HLDGS INC COM NEW 02081G201 33,961 2,786,000 SH   SOLE   2,786,000 0 0
ALPINE IMMUNE SCIENCES INC COM 02083G100 20,614 1,932,000 SH   SOLE   1,932,000 0 0
ALTIMMUNE INC COM NEW 02155H200 24,519 2,167,900 SH   SOLE   2,167,900 0 0
ARENA PHARMACEUTICALS INC COM NEW 040047607 67,827 1,139,000 SH   SOLE   1,139,000 0 0
ARROWHEAD PHARMACEUTICALS IN COM 04280A100 42,059 673,700 SH   SOLE   673,700 0 0
ARVINAS INC COM 04335A105 183,648 2,234,700 SH   SOLE   2,234,700 0 0
ARYA SCIENCES ACQU CORP IV CL A G31659108 5,025 500,000 SH   SOLE   500,000 0 0
ASTRAZENECA PLC SPONSORED ADR 046353108 84,805 1,412,000 SH   SOLE   1,412,000 0 0
ATAI LIFE SCIENCES NV SHS N0731H103 3,235 218,730 SH   SOLE   218,730 0 0
AVANTOR INC COM 05352A100 132,831 3,247,700 SH   SOLE   3,247,700 0 0
AVIDITY BIOSCIENCES INC COM 05370A108 40,516 1,645,000 SH   SOLE   1,645,000 0 0
BAXTER INTL INC COM 071813109 69,331 862,000 SH   SOLE   862,000 0 0
BCLS ACQUISITION CORP COM CL A G0904B105 4,980 500,000 SH   SOLE   500,000 0 0
BELLUS HEALTH INC NEW COM NEW 07987C204 30,344 4,942,000 SH   SOLE   4,942,000 0 0
BIOHAVEN PHARMACTL HLDG CO L COM G11196105 129,770 934,200 SH   SOLE   934,200 0 0
BLUEPRINT MEDICINES CORP COM 09627Y109 85,538 832,000 SH   SOLE   832,000 0 0
CAREMAX INC COM CL A 14171W103 7,993 827,402 SH   SOLE   827,402 0 0
CARIBOU BIOSCIENCES INC COM 142038108 59,056 2,474,067 SH   SOLE   2,474,067 0 0
CATALENT INC COM 148806102 52,962 398,000 SH   SOLE   398,000 0 0
CENTURY THERAPEUTICS INC COM 15673T100 18,600 739,269 SH   SOLE   739,269 0 0
COMPASS PATHWAYS PLC SPONSORED ADS 20451W101 34,709 1,162,000 SH   SOLE   1,162,000 0 0
CYTEIR THERAPEUTICS INC COM 23284P103 29,544 1,683,441 SH   SOLE   1,683,441 0 0
DYNAMICS SPECIAL PURPOSE COR CLASS A COM 268010105 4,970 500,000 SH   SOLE   500,000 0 0
ENGAGESMART INC COMMON STOCK 29283F103 9,367 275,000 SH   SOLE   275,000 0 0
ESSA PHARMA INC COM NEW 29668H708 19,600 2,450,000 SH   SOLE   2,450,000 0 0
EXACT SCIENCES CORP COM 30063P105 35,221 369,000 SH   SOLE   369,000 0 0
FIELD TRIP HEALTH LTD COM 31656R102 16,437 3,581,000 SH   SOLE   3,581,000 0 0
GH RESEARCH PLC ORDINARY SHARES G3855L106 12,354 560,000 SH   SOLE   560,000 0 0
GRAPHITE BIO INC COM 38870X104 12,276 748,995 SH   SOLE   748,995 0 0
GRITSTONE BIO INC COM 39868T105 48,145 4,457,831 SH   SOLE   4,457,831 0 0
HARPOON THERAPEUTICS INC COM 41358P106 9,406 1,190,600 SH   SOLE   1,190,600 0 0
HEALTH SCIENCES ACQ CORP 2 ORD SHS G4411D109 3,956 400,000 SH   SOLE   400,000 0 0
HEALTHCOR CATALIO ACQU CORP CL A SHS G44125105 4,950 500,000 SH   SOLE   500,000 0 0
HELIX ACQUISITION CORP COM CL A G4444C102 3,940 400,000 SH   SOLE   400,000 0 0
HOLOGIC INC COM 436440101 69,780 945,400 SH   SOLE   945,400 0 0
HORIZON THERAPEUTICS PUB L SHS G46188101 90,480 826,000 SH   SOLE   826,000 0 0
I MAB SPONSORED ADS 44975P103 32,910 454,000 SH   SOLE   454,000 0 0
IDEAYA BIOSCIENCES INC COM 45166A102 62,119 2,437,000 SH   SOLE   2,437,000 0 0
IMMUNOCORE HLDGS PLC ADS 45258D105 40,614 1,095,600 SH   SOLE   1,095,600 0 0
INSMED INC COM PAR $.01 457669307 35,582 1,292,000 SH   SOLE   1,292,000 0 0
INSTIL BIO INC COM 45783C101 7,296 408,140 SH   SOLE   408,140 0 0
INTELLIA THERAPEUTICS INC COM 45826J105 33,672 251,000 SH   SOLE   251,000 0 0
IOVANCE BIOTHERAPEUTICS INC COM 462260100 36,058 1,462,200 SH   SOLE   1,462,200 0 0
IVERIC BIO INC COM 46583P102 66,584 4,100,000 SH   SOLE   4,100,000 0 0
KEROS THERAPEUTICS INC COM 492327101 5,740 145,100 SH   SOLE   145,100 0 0
KEZAR LIFE SCIENCES INC COM 49372L100 2,246 260,000 SH   SOLE   260,000 0 0
KYMERA THERAPEUTICS INC COM 501575104 30,222 514,500 SH   SOLE   514,500 0 0
LEGEND BIOTECH CORP SPONSORED ADS 52490G102 45,201 894,000 SH   SOLE   894,000 0 0
LIFESCI ACQUISITION II CORP COM 53229E103 3,920 400,000 SH   SOLE   400,000 0 0
LIFESTANCE HEALTH GROUP INC COM 53228F101 14,500 1,000,000 SH   SOLE   1,000,000 0 0
LILLY ELI & CO COM 532457108 76,247 330,000 SH   SOLE   330,000 0 0
MEDICUS SCIENCES ACQUISITION CL A SHS G5960S108 5,070 520,000 SH   SOLE   520,000 0 0
MEDICUS SCIENCES ACQUISITION *W EXP 02/12/202 G5960S124 41 57,770 SH   SOLE   57,770 0 0
MIRATI THERAPEUTICS INC COM 60468T105 187,949 1,062,400 SH   SOLE   1,062,400 0 0
MONTE ROSA THERAPEUTICS INC COM 61225M102 6,684 300,000 SH   SOLE   300,000 0 0
NATERA INC COM 632307104 71,177 638,700 SH   SOLE   638,700 0 0
NAUTILUS BIOTECHNOLOGY INC COM 63909J108 3,684 600,000 SH   SOLE   600,000 0 0
NEUROCRINE BIOSCIENCES INC COM 64125C109 81,418 848,900 SH   SOLE   848,900 0 0
NUVATION BIO INC COM CL A 67080N101 72,199 7,263,488 SH   SOLE   7,263,488 0 0
NUVATION BIO INC *W EXP 07/07/202 67080N119 253 99,999 SH   SOLE   99,999 0 0
ONCOSEC MED INC COM 68234L306 6,273 2,945,000 SH   SOLE   2,945,000 0 0
ORCHARD THERAPEUTICS PLC ADS 68570P101 8,825 3,836,798 SH   SOLE   3,836,798 0 0
ORTHO CLINICAL DIAGNOSTICS H ORD SHS G6829J107 44,315 2,398,000 SH   SOLE   2,398,000 0 0
PANACEA ACQUISITION CORP II CL A SHS G6882C106 4,885 500,000 SH   SOLE   500,000 0 0
PFIZER INC COM 717081103 44,163 1,026,800 SH   SOLE   1,026,800 0 0
PHASEBIO PHARMACEUTICALS INC COM 717224109 13,700 4,405,000 SH   SOLE   4,405,000 0 0
REGENERON PHARMACEUTICALS COM 75886F107 92,169 152,300 SH   SOLE   152,300 0 0
SANA BIOTECHNOLOGY INC COM 799566104 17,445 774,644 SH   SOLE   774,644 0 0
SCYNEXIS INC COM NEW 811292200 10,918 2,060,000 SH   SOLE   2,060,000 0 0
SEAGEN INC COM 81181C104 91,183 537,000 SH   SOLE   537,000 0 0
SEASPINE HLDGS CORP COM 81255T108 30,563 1,943,000 SH   SOLE   1,943,000 0 0
SEMA4 HOLDINGS CORP COM CL A 81663L101 12,599 1,660,000 SH   SOLE   1,660,000 0 0
SENTINELONE INC CL A 81730H109 10,714 200,000 SH   SOLE   200,000 0 0
SHATTUCK LABS INC COM 82024L103 41,270 2,025,000 SH   SOLE   2,025,000 0 0
SI-BONE INC COM 825704109 17,804 831,200 SH   SOLE   831,200 0 0
SIGHT SCIENCES INC COM 82657M105 3,296 145,189 SH   SOLE   145,189 0 0
SOCIAL CAP SUVRETTA HLD CRPI CLASS A ORD SHS G8253W109 1,960 200,000 SH   SOLE   200,000 0 0
SOCIAL CAP SUVRETTA HLDS CP CLASS A ORD SHS G8253Y105 1,962 200,000 SH   SOLE   200,000 0 0
SOCIAL CAP SUVRETTA HLDS CRP CLASS A ORD SHS G8253T106 1,990 200,000 SH   SOLE   200,000 0 0
SOCIAL CAP SUVRETTA HLDS CRP CLASS A ORD SHS G8253U103 1,976 200,000 SH   SOLE   200,000 0 0
SOMALOGIC INC CLASS A COM 83444K105 4,089 330,000 SH   SOLE   330,000 0 0
SOMALOGIC INC *W EXP 03/01/202 83444K113 228 65,999 SH   SOLE   65,999 0 0
SOTERA HEALTH CO COM 83601L102 62,185 2,378,000 SH   SOLE   2,378,000 0 0
SPDR SER TR S&P BIOTECH 78464A870 379,770 3,021,000 SH Call SOLE   3,021,000 0 0
STEVANATO GROUP S P A ORD SHS T9224W109 64,335 2,541,893 SH   SOLE   2,541,893 0 0
SYNDAX PHARMACEUTICALS INC COM 87164F105 92,175 4,823,400 SH   SOLE   4,823,400 0 0
TALARIS THERAPEUTICS INC COM 87410C104 6,170 455,000 SH   SOLE   455,000 0 0
TANGO THERAPEUTICS INC COM 87583X109 3,879 300,000 SH   SOLE   300,000 0 0
UIPATH INC CL A 90364P105 16,783 319,000 SH   SOLE   319,000 0 0
ULTRAGENYX PHARMACEUTICAL IN COM 90400D108 41,036 455,000 SH   SOLE   455,000 0 0
UNITED THERAPEUTICS CORP DEL COM 91307C102 64,788 351,000 SH   SOLE   351,000 0 0
VERTEX PHARMACEUTICALS INC COM 92532F100 168,040 926,400 SH   SOLE   926,400 0 0
VIR BIOTECHNOLOGY INC COM 92764N102 22,413 515,000 SH   SOLE   515,000 0 0
WEREWOLF THERAPEUTICS INC COM 95075A107 10,727 625,120 SH   SOLE   625,120 0 0
ZAI LAB LTD ADR 98887Q104 3,752 35,600 SH   SOLE   35,600 0 0
ZENTALIS PHARMACEUTICALS INC COM 98943L107 166,187 2,493,800 SH   SOLE   2,493,800 0 0
ZETA GLOBAL HOLDINGS CORP CL A 98956A105 7,618 1,300,000 SH   SOLE   1,300,000 0 0
ZIOPHARM ONCOLOGY INC COM 98973P101 5,460 3,000,000 SH   SOLE   3,000,000 0 0