The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
10X Genomics Inc CL A Common 88025U109 2,154 14,798 SH   SOLE   14,798 0 0
Aadi Bioscience Inc Common 00032Q104 41,917 1,427,213 SH   SOLE   1,427,213 0 0
Aclaris Therapeutics, Inc. Common 00461U105 16,934 940,754 SH   SOLE   940,754 0 0
Aligos Therapeutics Inc Common 01626L105 55,014 3,547,030 SH   SOLE   3,547,030 0 0
ALX Oncology Holdings Inc Common 00166B105 311,693 4,220,048 SH   SOLE   4,220,048 0 0
Amyris, Inc Common 03236M200 159,847 11,642,195 SH   SOLE   11,642,195 0 0
Arcutis Biotherapeutics Inc Common 03969K108 10,358 433,585 SH   SOLE   433,585 0 0
Arrowhead Pharmaceuticals Inc Common 04280A100 8,579 137,411 SH   SOLE   137,411 0 0
Ascendis Pharma A/S SPONSORED ADR 04351P101 121,233 760,606 SH   SOLE   760,606 0 0
Aslan Pharmaceuticals Ltd ADS 04522R101 5,057 2,840,909 SH   SOLE   2,840,909 0 0
Aurinia Pharmaceuticals Inc. Common 05156V102 11,081 500,732 SH   SOLE   500,732 0 0
Avadel Pharmaceuticals PLC ADR 05337M104 28,784 2,937,093 SH   SOLE   2,937,093 0 0
Bolt Therapeutics Inc Common 097702104 48,972 3,871,291 SH   SOLE   3,871,291 0 0
Celldex Therapeutics Inc Common 15117B202 26,156 484,453 SH   SOLE   484,453 0 0
Chinook Therapeutics Inc Common 16961L106 11,129 872,151 SH   SOLE   872,151 0 0
Codexis, Inc Common 192005106 9,028 388,144 SH   SOLE   388,144 0 0
Cogent Biosciences Inc Common 19240Q201 11,950 1,420,941 SH   SOLE   1,420,941 0 0
Crinetics Pharmaceuticals Inc Common 22663K107 10,889 517,280 SH   SOLE   517,280 0 0
Curis Inc Common 231269200 12,164 1,553,500 SH   SOLE   1,553,500 0 0
Design Therapeutics Common 25056L103 7,800 530,991 SH   SOLE   530,991 0 0
Dice Therapeutics Inc Common 23345J104 13,428 410,000 SH   SOLE   410,000 0 0
Dyne Therapeutics Inc Common 26818M108 9,381 577,642 SH   SOLE   577,642 0 0
Eiger BioPharmaceuticals Inc Common 28249U105 3,137 469,588 SH   SOLE   469,588 0 0
Elevation Oncology Inc Common 28623U101 3,870 496,843 SH   SOLE   496,843 0 0
Essa Pharma Inc Common 29668H708 8,449 1,056,067 SH   SOLE   1,056,067 0 0
Genetron Holdings Ltd ADS 37186H100 87,807 6,339,860 SH   SOLE   6,339,860 0 0
Gracell Biotechnologies Inc SPONSORED ADS 38406L103 13,334 961,359 SH   SOLE   961,359 0 0
Harmony Biosciences Holdings Inc Common 413197104 187,217 4,884,341 SH   SOLE   4,884,341 0 0
Homology Medicines, Inc. Common 438083107 6,714 853,143 SH   SOLE   853,143 0 0
Impel NeuroPharma Inc Common 45258K109 35,137 2,884,789 SH   SOLE   2,884,789 0 0
Instil Bio Inc Common 45783C101 223,201 12,486,787 SH   SOLE   12,486,787 0 0
Iveric Bio Inc Common 46583P102 96,896 5,966,527 SH   SOLE   5,966,527 0 0
Kadmon Holdings Inc Common 48283N106 37,305 4,283,014 SH   SOLE   4,283,014 0 0
KalVista Pharmaceuticals Inc. Common 483497103 28,651 1,641,913 SH   SOLE   1,641,913 0 0
Kura Oncology Inc Common 50127T109 9,838 525,262 SH   SOLE   525,262 0 0
Larimar Therapeutics Inc Common 517125100 4,610 399,830 SH   SOLE   399,830 0 0
Legend Biotech Corp Sponsored SPONSORED ADS 52490G102 24,711 488,751 SH   SOLE   488,751 0 0
Mereo Biopharma Group PLC ADS 589492107 16,715 6,907,189 SH   SOLE   6,907,189 0 0
Merus NV Common N5749R100 9,724 442,000 SH   SOLE   442,000 0 0
Metacrine Inc Common 59101E103 502 146,426 SH   SOLE   146,426 0 0
New Frontier Health Corp Ord Shs G6461G106 160,589 14,300,000 SH   SOLE   14,300,000 0 0
Nkarta Inc Common 65487U108 14,245 512,225 SH   SOLE   512,225 0 0
Olema Pharmaceuticals Inc Common 68062P106 34,135 1,238,575 SH   SOLE   1,238,575 0 0
Orchard Therapeutics plc ADS 68570P101 3,049 1,325,736 SH   SOLE   1,325,736 0 0
Passage Bio Inc Common 702712100 5,371 539,263 SH   SOLE   539,263 0 0
Precision Biosciences Inc Common 74019P108 1,619 140,255 SH   SOLE   140,255 0 0
Satsuma Pharmaceuticals Inc Common 80405P107 5,743 1,232,394 SH   SOLE   1,232,394 0 0
Sera Prognostics Inc Common 81749D107 20,620 1,856,011 SH   SOLE   1,856,011 0 0
Sierra Oncology, Inc Common 82640U404 42,022 1,917,074 SH   SOLE   1,917,074 0 0
Sinovac Biotech Ltd. SHS P8696W104 38,173 5,900,000 SH   SOLE   5,900,000 0 0
Syndax Pharmaceuticals Inc Common 87164F105 6,115 320,000 SH   SOLE   320,000 0 0
Tarsus Pharmaceuticals Inc Common 87650L103 64,377 2,987,331 SH   SOLE   2,987,331 0 0
Terns Pharmaceuticals Inc Common 880881107 27,875 2,675,133 SH   SOLE   2,675,133 0 0
Tricida, Inc. Common 89610F101 779 167,863 SH   SOLE   167,863 0 0
Valneva SE SPONSORED ADS 92025Y103 6,280 200,000 SH   SOLE   200,000 0 0
Verona Pharma PLC ADS 925050106 15,070 2,749,918 SH   SOLE   2,749,918 0 0
Viridian Therapeutics Inc Common 92790C104 21,385 1,300,000 SH   SOLE   1,300,000 0 0
Zai Lab Ltd ADR ADR 98887Q104 18,443 174,999 SH   SOLE   174,999 0 0
Zogenix Inc Common 98978L204 1,595 105,000 SH   SOLE   105,000 0 0
Zymeworks Inc Common 98985W102 8,307 286,064 SH   SOLE   286,064 0 0