The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
AC IMMUNE SA SHS H00263105 6,465 963,500 SH   SOLE   963,500 0 0
ADAGENE INC ADS 005329107 614 42,722 SH   SOLE   42,722 0 0
ADOBE SYSTEMS INCORPORATED COM 00724F101 365,359 634,613 SH   SOLE   634,613 0 0
AEGLEA BIOTHERAPEUTICS INC COM 00773J103 17,154 2,157,727 SH   SOLE   2,157,727 0 0
AGIOS PHARMACEUTICALS INC COM 00847X104 60,537 1,311,748 SH   SOLE   1,311,748 0 0
ALIGHT INC *W EXP 05/26/202 01626W119 2,362 774,375 SH   SOLE   774,375 0 0
ALIGHT INC COM CL A 01626W101 95,858 8,350,000 SH   SOLE   8,350,000 0 0
AMAZON COM INC COM 023135106 325,669 99,137 SH   SOLE   99,137 0 0
AMERISOURCEBERGEN CORP COM 03073E105 147,502 1,234,845 SH   SOLE   1,234,845 0 0
ANALOG DEVICES INC COM 032654105 79,996 477,645 SH   SOLE   477,645 0 0
ANAPLAN INC COM 03272L108 131,841 2,165,238 SH   SOLE   2,165,238 0 0
ARCHER AVIATION INC COM CL A 03945R102 6,660 750,000 SH   SOLE   750,000 0 0
ARENA PHARMACEUTICALS INC COM NEW 040047607 30,197 507,088 SH   SOLE   507,088 0 0
BCLS ACQUISITION CORP COM CL A G0904B105 1,992 200,000 SH   SOLE   200,000 0 0
BENITEC BIOPHARMA INC COM 08205P100 2,745 769,000 SH   SOLE   769,000 0 0
BIOATLA INC COM 09077B104 10,427 354,190 SH   SOLE   354,190 0 0
BOLT BIOTHERAPEUTICS INC COM 097702104 16,768 1,325,500 SH   SOLE   1,325,500 0 0
CANO HEALTH INC *W EXP 06/03/202 13781Y111 2,786 674,566 SH   SOLE   674,566 0 0
CANO HEALTH INC COM CL A 13781Y103 106,753 8,419,011 SH   SOLE   8,419,011 0 0
CARVANA CO CL A 146869102 144,481 479,143 SH   SOLE   479,143 0 0
CAZOO GROUP LTD COM G2007L105 11,730 1,509,700 SH   SOLE   1,509,700 0 0
CHIMERIX INC COM 16934W106 11,808 1,907,620 SH   SOLE   1,907,620 0 0
CHINOOK THERAPEUTICS INC COM 16961L106 13,366 1,047,468 SH   SOLE   1,047,468 0 0
COHERUS BIOSCIENCES INC COM 19249H103 7,864 489,333 SH   SOLE   489,333 0 0
COPART INC COM 217204106 121,070 872,764 SH   SOLE   872,764 0 0
DECIBEL THERAPEUTICS INC COM 24343R106 2,032 263,600 SH   SOLE   263,600 0 0
DECIPHERA PHARMACEUTICALS IN COM 24344T101 29,295 862,126 SH   SOLE   862,126 0 0
DICE THERAPEUTICS INC COM 23345J104 13,428 410,000 SH   SOLE   410,000 0 0
ELASTIC N V ORD SHS N14506104 40,376 271,000 SH   SOLE   271,000 0 0
EUCRATES BIOMEDICAL ACQU COR *W EXP 10/23/202 G3141W122 24 33,333 SH   SOLE   33,333 0 0
EUCRATES BIOMEDICAL ACQU COR SHS G3141W106 978 99,999 SH   SOLE   99,999 0 0
EUROPEAN BIOTECH ACQUTN CORP *W EXP 03/06/202 G3167F128 62 100,000 SH   SOLE   100,000 0 0
EUROPEAN BIOTECH ACQUTN CORP CLASS A ORD SHS G3167F102 2,901 300,000 SH   SOLE   300,000 0 0
EVOLV TECHNOLOGIES HLDNGS IN COM CL A 30049H102 8,207 1,367,870 SH   SOLE   1,367,870 0 0
EYEPOINT PHARMACEUTICALS INC COM NEW 30233G209 17,762 1,704,589 SH   SOLE   1,704,589 0 0
FINSERV ACQUISITION CORP II *W EXP 02/17/202 31809Y111 243 273,149 SH   SOLE   273,149 0 0
FINSERV ACQUISITION CORP II COM CL A 31809Y103 10,631 1,092,600 SH   SOLE   1,092,600 0 0
FOGHORN THERAPEUTICS INC COM 344174107 1,170 84,000 SH   SOLE   84,000 0 0
FRAZIER LIFESCIENCES ACQU CO *W EXP 11/30/202 G3710A113 20 29,166 SH   SOLE   29,166 0 0
FRAZIER LIFESCIENCES ACQU CO CL A SHS G3710A105 859 87,498 SH   SOLE   87,498 0 0
FRESHWORKS INC CLASS A COM 358054104 6,404 150,000 SH   SOLE   150,000 0 0
FREYR BATTERY SHS L4135L100 20,665 2,093,710 SH   SOLE   2,093,710 0 0
FS DEVELOPMENT CORP II COM CL A 30318F100 3,980 400,000 SH   SOLE   400,000 0 0
FULCRUM THERAPEUTICS INC COM 359616109 54,783 1,941,969 SH   SOLE   1,941,969 0 0
GEMINI THERAPEUTICS INC COM 36870G105 8,637 2,137,823 SH   SOLE   2,137,823 0 0
GFL ENVIRONMENTAL INC SUB VTG SHS 36168Q104 175,167 4,715,117 SH   SOLE   4,715,117 0 0
HEALTHCOR CATALIO ACQU CORP CL A SHS G44125105 2,970 300,000 SH   SOLE   300,000 0 0
HERON THERAPEUTICS INC COM 427746102 15,933 1,490,440 SH   SOLE   1,490,440 0 0
HOWMET AEROSPACE INC COM 443201108 79,598 2,551,230 SH   SOLE   2,551,230 0 0
IMMUNEERING CORP CLASS A COM 45254E107 5,310 200,000 SH   SOLE   200,000 0 0
INFLARX NV COM N44821101 8,508 3,285,000 SH   SOLE   3,285,000 0 0
INOZYME PHARMA INC COM 45790W108 11,432 986,400 SH   SOLE   986,400 0 0
INSMED INC COM PAR $.01 457669307 27,505 998,732 SH   SOLE   998,732 0 0
INTRA-CELLULAR THERAPIES INC COM 46116X101 46,673 1,251,946 SH   SOLE   1,251,946 0 0
IQVIA HLDGS INC COM 46266C105 168,441 703,187 SH   SOLE   703,187 0 0
KALVISTA PHARMACEUTICALS INC COM 483497103 26,930 1,543,284 SH   SOLE   1,543,284 0 0
KBR INC COM 48242W106 117,545 2,983,377 SH   SOLE   2,983,377 0 0
KEZAR LIFE SCIENCES INC COM 49372L100 12,182 1,409,956 SH   SOLE   1,409,956 0 0
KURA ONCOLOGY INC COM 50127T109 46,080 2,460,202 SH   SOLE   2,460,202 0 0
LAUDER ESTEE COS INC CL A 518439104 153,988 513,414 SH   SOLE   513,414 0 0
MARINUS PHARMACEUTICALS INC COM NEW 56854Q200 25,007 2,197,426 SH   SOLE   2,197,426 0 0
MASTERCARD INCORPORATED CL A 57636Q104 234,475 674,400 SH   SOLE   674,400 0 0
MASTERCARD INCORPORATED CL A 57636Q104 60,010 172,600 SH Call SOLE   172,600 0 0
MEDTRONIC PLC SHS G5960L103 114,222 911,226 SH   SOLE   911,226 0 0
MEREO BIOPHARMA GROUP PLC ADS 589492107 22,124 9,142,067 SH   SOLE   9,142,067 0 0
MILESTONE PHARMACEUTICALS IN COM 59935V107 4,861 851,291 SH   SOLE   851,291 0 0
MIRATI THERAPEUTICS INC COM 60468T105 33,844 191,308 SH   SOLE   191,308 0 0
MOLECULAR PARTNERS AG ADS 60853G106 7,844 400,000 SH   SOLE   400,000 0 0
MONTES ARCHIMEDES ACQUISITIO COM CL A 612657106 4,675 500,000 SH   SOLE   500,000 0 0
NATERA INC COM 632307104 83,270 747,220 SH   SOLE   747,220 0 0
NAUTILUS BIOTECHNOLOGY INC COM 63909J108 1,933 314,835 SH   SOLE   314,835 0 0
NERDY INC CL A COM 64081V109 6,993 700,000 SH   SOLE   700,000 0 0
NEXIMMUNE INC COM 65344D109 5,212 344,223 SH   SOLE   344,223 0 0
NUVALENT INC COM 670703107 4,510 200,000 SH   SOLE   200,000 0 0
NXP SEMICONDUCTORS N V COM N6596X109 50,229 256,438 SH   SOLE   256,438 0 0
OMEGA ALPHA SPAC CL A G6749V107 2,921 300,000 SH   SOLE   300,000 0 0
OPENDOOR TECHNOLOGIES INC COM 683712103 193,944 9,446,879 SH   SOLE   9,446,879 0 0
ORIC PHARMACEUTICALS INC COM 68622P109 3,118 149,100 SH   SOLE   149,100 0 0
OTIS WORLDWIDE CORP COM 68902V107 222,118 2,699,539 SH   SOLE   2,699,539 0 0
OTONOMY INC COM 68906L105 4,584 2,387,700 SH   SOLE   2,387,700 0 0
PELOTON INTERACTIVE INC CL A COM 70614W100 101,570 1,166,800 SH   SOLE   1,166,800 0 0
POINT BIOPHARMA GLOBAL INC COM 730541109 17,110 2,225,000 SH   SOLE   2,225,000 0 0
PROMETHEUS BIOSCIENCES INC COM 74349U108 11,392 480,480 SH   SOLE   480,480 0 0
QUANTA SVCS INC COM 74762E102 158,077 1,388,834 SH   SOLE   1,388,834 0 0
RESEARCH ALLIANCE CORP II COM CL A 760873109 4,925 500,000 SH   SOLE   500,000 0 0
RH COM 74967X103 223,382 334,951 SH   SOLE   334,951 0 0
ROCKET LAB USA INC COM 773122106 12,098 750,000 SH   SOLE   750,000 0 0
ROSS STORES INC COM 778296103 121,687 1,117,935 SH   SOLE   1,117,935 0 0
ROYALTY PHARMA PLC SHS CLASS A G7709Q104 55,218 1,527,900 SH   SOLE   1,527,900 0 0
SIO GENE THERAPIES INC COMMON 829399104 11,911 5,489,000 SH   SOLE   5,489,000 0 0
SOLID BIOSCIENCES INC COM 83422E105 14,278 5,974,193 SH   SOLE   5,974,193 0 0
SQUARE INC CL A 852234103 72,655 302,930 SH   SOLE   302,930 0 0
SUTRO BIOPHARMA INC COM 869367102 42,194 2,233,695 SH   SOLE   2,233,695 0 0
SYNLOGIC INC COM 87166L100 183 60,000 SH   SOLE   60,000 0 0
TAPESTRY INC COM 876030107 199,095 5,378,032 SH   SOLE   5,378,032 0 0
TE CONNECTIVITY LTD REG SHS H84989104 82,864 603,877 SH   SOLE   603,877 0 0
TERNS PHARMACEUTICALS INC COM 880881107 11,730 1,125,736 SH   SOLE   1,125,736 0 0
THERMO FISHER SCIENTIFIC INC COM 883556102 186,145 325,810 SH   SOLE   325,810 0 0
TURMERIC ACQUISITION CORP *W EXP 10/08/202 G9127T124 46 66,666 SH   SOLE   66,666 0 0
TURMERIC ACQUISITION CORP CL A G9127T108 1,958 200,000 SH   SOLE   200,000 0 0
TWILIO INC CL A 90138F102 164,796 516,520 SH   SOLE   516,520 0 0
UNION PAC CORP COM 907818108 160,669 819,697 SH   SOLE   819,697 0 0
UNITEDHEALTH GROUP INC COM 91324P102 279,423 715,113 SH   SOLE   715,113 0 0
VOLTA INC COM CL A 92873V102 2,595 300,000 SH   SOLE   300,000 0 0
WARBY PARKER INC CL A COM 93403J106 53,050 1,000,000 SH   SOLE   1,000,000 0 0
XENON PHARMACEUTICALS INC COM 98420N105 17,709 1,158,961 SH   SOLE   1,158,961 0 0