The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ABSCI CORPORATION COM 00091E109 65,855 8,031,094 SH   SOLE   8,031,094 0 0
ACHILLES THERAPEUTICS PLC SPONSORED ADS 00449L102 10,461 2,088,089 SH   SOLE   2,088,089 0 0
ADAGIO THERAPEUTICS INC COM 00534A102 13,946 1,920,960 SH   SOLE   1,920,960 0 0
ADC THERAPEUTICS SA SHS H0036K147 150,511 7,451,029 SH   SOLE   7,451,029 0 0
AKERO THERAPEUTICS INC COM 00973Y108 33,888 1,602,285 SH   SOLE   1,602,285 0 0
ALLAKOS INC COM 01671P100 20,342 2,077,875 SH   SOLE   2,077,875 0 0
ALLOVIR INC COM 019818103 10,654 823,371 SH   SOLE   823,371 0 0
ALPHA TEKNOVA INC COM 02080L102 14,848 725,000 SH   SOLE   725,000 0 0
ALX ONCOLOGY HLDGS INC COM 00166B105 16,807 782,097 SH   SOLE   782,097 0 0
AMICUS THERAPEUTICS INC COM 03152W109 262,371 22,716,086 SH   SOLE   22,716,086 0 0
ANNEXON INC COM 03589W102 37,100 3,228,917 SH   SOLE   3,228,917 0 0
ANTHEM INC COM 036752103 51,123 110,289 SH   SOLE   110,289 0 0
ARGENX SE SPONSORED ADR 04016X101 182,674 521,643 SH   SOLE   521,643 0 0
ATARA BIOTHERAPEUTICS INC COM 046513107 101,459 6,437,777 SH   SOLE   6,437,777 0 0
ATRECA INC CL A COM 04965G109 2,425 800,306 SH   SOLE   800,306 0 0
AUGMEDIX INC COM 05105P107 45,298 14,380,327 SH   SOLE   14,380,327 0 0
AVITA MEDICAL INC COM 05380C102 8,055 672,411 SH   SOLE   672,411 0 0
AYALA PHARMACEUTICALS INC COM 05465V108 5,683 667,816 SH   SOLE   667,816 0 0
BEAM THERAPEUTICS INC COM 07373V105 150,283 1,885,850 SH   SOLE   1,885,850 0 0
BIOVENTUS INC COM CL A 09075A108 19,201 1,325,139 SH   SOLE   1,325,139 0 0
CABALETTA BIO INC COM 12674W109 2,639 696,377 SH   SOLE   696,377 0 0
CELLDEX THERAPEUTICS INC NEW COM NEW 15117B202 83,678 2,165,586 SH   SOLE   2,165,586 0 0
CENTENE CORP DEL COM 15135B101 29,758 361,139 SH   SOLE   361,139 0 0
CYTOSORBENTS CORP COM NEW 23283X206 3,005 717,244 SH   SOLE   717,244 0 0
DECIPHERA PHARMACEUTICALS IN COM 24344T101 6,495 664,817 SH   SOLE   664,817 0 0
ENTRADA THERAPEUTICS INC COM 29384C108 33,460 1,954,420 SH   SOLE   1,954,420 0 0
EPIZYME INC COM 29428V104 1,136 454,475 SH   SOLE   454,475 0 0
FATE THERAPEUTICS INC COM 31189P102 758,127 12,957,222 SH   SOLE   12,957,222 0 0
GENMAB A/S SPONSORED ADS 372303206 26,174 661,621 SH   SOLE   661,621 0 0
GRITSTONE BIO INC COM 39868T105 44,099 3,429,171 SH   SOLE   3,429,171 0 0
HOOKIPA PHARMA INC COM 43906K100 5,557 2,385,136 SH   SOLE   2,385,136 0 0
ICU MED INC COM 44930G107 52,197 219,926 SH   SOLE   219,926 0 0
IGM BIOSCIENCES INC COM 449585108 97,797 3,334,355 SH   SOLE   3,334,355 0 0
IMMATICS N.V SHS N44445109 23,731 1,765,692 SH   SOLE   1,765,692 0 0
IMMUNOGEN INC COM 45253H101 61,277 8,258,345 SH   SOLE   8,258,345 0 0
INVITAE CORP COM 46185L103 58,109 3,805,403 SH   SOLE   3,805,403 0 0
IVERIC BIO INC COM 46583P102 25,080 1,500,000 SH   SOLE   1,500,000 0 0
JAZZ PHARMACEUTICALS PLC SHS USD G50871105 12,493 98,064 SH   SOLE   98,064 0 0
KRYSTAL BIOTECH INC COM 501147102 127,372 1,820,898 SH   SOLE   1,820,898 0 0
KYMERA THERAPEUTICS INC COM 501575104 164,295 2,587,730 SH   SOLE   2,587,730 0 0
LAVA THERAPEUTICS NV SHS N51517105 15,489 2,816,196 SH   SOLE   2,816,196 0 0
LIVANOVA PLC SHS G5509L101 179,859 2,057,178 SH   SOLE   2,057,178 0 0
MEDAVAIL HOLDINGS INC COM 58406B103 15,505 11,075,105 SH   SOLE   11,075,105 0 0
NEOLEUKIN THERAPEUTICS INC COM 64049K104 16,826 3,490,835 SH   SOLE   3,490,835 0 0
NEVRO CORP COM 64157F103 21,898 270,116 SH   SOLE   270,116 0 0
NGM BIOPHARMACEUTICALS INC COM 62921N105 10,321 582,805 SH   SOLE   582,805 0 0
NURIX THERAPEUTICS INC COM 67080M103 85,642 2,958,284 SH   SOLE   2,958,284 0 0
NUVATION BIO INC COM CL A 67080N101 31,204 3,671,009 SH   SOLE   3,671,009 0 0
OAK STR HEALTH INC COM 67181A107 39,888 1,203,619 SH   SOLE   1,203,619 0 0
PLIANT THERAPEUTICS INC COM 729139105 41,627 3,083,501 SH   SOLE   3,083,501 0 0
PROTHENA CORP PLC SHS G72800108 37,824 765,675 SH   SOLE   765,675 0 0
REGENXBIO INC COM 75901B107 62,039 1,897,223 SH   SOLE   1,897,223 0 0
REPARE THERAPEUTICS INC COM 760273102 58,830 2,789,496 SH   SOLE   2,789,496 0 0
REPLIMUNE GROUP INC COM 76029N106 104,782 3,866,512 SH   SOLE   3,866,512 0 0
SCHOLAR ROCK HLDG CORP COM 80706P103 60,806 2,447,926 SH   SOLE   2,447,926 0 0
SCIENCE 37 HOLDINGS INC COM 808644108 247,009 19,808,234 SH   SOLE   19,808,234 0 0
SEAGEN INC COM 81181C104 57,486 371,839 SH   SOLE   371,839 0 0
SHATTUCK LABS INC COM 82024L103 47,825 5,619,914 SH   SOLE   5,619,914 0 0
SOMALOGIC INC CLASS A COM 83444K105 48,222 4,142,770 SH   SOLE   4,142,770 0 0
SONENDO INC COM 835431107 2,869 498,131 SH   SOLE   498,131 0 0
STEREOTAXIS INC COM NEW 85916J409 10,529 1,698,204 SH   SOLE   1,698,204 0 0
STEVANATO GROUP S P A ORD SHS T9224W109 26,272 1,170,225 SH   SOLE   1,170,225 0 0
STOKE THERAPEUTICS INC COM 86150R107 53,898 2,246,668 SH   SOLE   2,246,668 0 0
TCR2 THERAPEUTICS INC COM 87808K106 6,273 1,346,058 SH   SOLE   1,346,058 0 0
THE BEAUTY HEALTH COMPANY COM CL A 88331L108 122,801 5,082,805 SH   SOLE   5,082,805 0 0
THE ONCOLOGY INSTITUTE INC COM 68236X100 24,375 2,500,000 SH   SOLE   2,500,000 0 0
UNITEDHEALTH GROUP INC COM 91324P102 52,468 104,488 SH   SOLE   104,488 0 0
VERVE THERAPEUTICS INC COM 92539P101 62,994 1,708,536 SH   SOLE   1,708,536 0 0
XERIS BIOPHARMA HOLDINGS INC COM 98422E103 3,066 1,046,587 SH   SOLE   1,046,587 0 0
ZOGENIX INC COM NEW 98978L204 16,219 998,114 SH   SOLE   998,114 0 0
ZYMEWORKS INC COM 98985W102 14,331 874,397 SH   SOLE   874,397 0 0