The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ABCELLERA BIOLOGICS INC COM 00288U106 5,250 367,100 SH Call SOLE   367,100 0 0
ADOBE SYSTEMS INCORPORATED COM 00724F101 222,405 392,207 SH   SOLE   392,207 0 0
AEGLEA BIOTHERAPEUTICS INC COM 00773J103 12,212 2,571,000 SH   SOLE   2,571,000 0 0
AGIOS PHARMACEUTICALS INC COM 00847X104 38,700 1,177,374 SH   SOLE   1,177,374 0 0
ALIGHT INC COM CL A 01626W101 84,426 7,810,000 SH   SOLE   7,810,000 0 0
ALLOGENE THERAPEUTICS INC COM 019770106 3,956 265,116 SH   SOLE   265,116 0 0
AMAZON COM INC COM 023135106 360,209 108,030 SH   SOLE   108,030 0 0
AMBRX BIOPHARMA INC SPONSORED ADS 02290A102 9,551 1,057,735 SH   SOLE   1,057,735 0 0
AMERISOURCEBERGEN CORP COM 03073E105 165,290 1,243,810 SH   SOLE   1,243,810 0 0
ANALOG DEVICES INC COM 032654105 144,010 819,310 SH   SOLE   819,310 0 0
ARENA PHARMACEUTICALS INC COM NEW 040047607 22,845 245,800 SH   SOLE   245,800 0 0
BCLS ACQUISITION CORP COM CL A G0904B105 1,960 200,000 SH   SOLE   200,000 0 0
BENITEC BIOPHARMA INC COM 08205P100 2,015 769,000 SH   SOLE   769,000 0 0
BLOCK INC CL A 852234103 69,447 429,984 SH   SOLE   429,984 0 0
BOLT BIOTHERAPEUTICS INC COM 097702104 10,928 2,230,250 SH   SOLE   2,230,250 0 0
CANO HEALTH INC *W EXP 06/03/202 13781Y111 1,612 674,566 SH   SOLE   674,566 0 0
CANO HEALTH INC COM CL A 13781Y103 87,968 9,872,990 SH   SOLE   9,872,990 0 0
CARVANA CO CL A 146869102 99,161 427,807 SH   SOLE   427,807 0 0
CHIMERIX INC COM 16934W106 17,789 2,766,619 SH   SOLE   2,766,619 0 0
CHINOOK THERAPEUTICS INC COM 16961L106 20,346 1,247,468 SH   SOLE   1,247,468 0 0
COHERUS BIOSCIENCES INC COM 19249H103 19,452 1,218,792 SH   SOLE   1,218,792 0 0
COPART INC COM 217204106 46,244 305,000 SH   SOLE   305,000 0 0
DANAHER CORPORATION COM 235851102 72,448 220,200 SH   SOLE   220,200 0 0
DECIBEL THERAPEUTICS INC COM 24343R106 1,226 263,600 SH   SOLE   263,600 0 0
DECKERS OUTDOOR CORP COM 243537107 79,207 216,230 SH   SOLE   216,230 0 0
DICE THERAPEUTICS INC COM 23345J104 10,377 410,000 SH   SOLE   410,000 0 0
ENTRADA THERAPEUTICS INC COM 29384C108 1,815 106,000 SH   SOLE   106,000 0 0
ETSY INC COM 29786A106 26,745 122,158 SH   SOLE   122,158 0 0
EUCRATES BIOMEDICAL ACQU COR *W EXP 10/23/202 G3141W122 19 33,333 SH   SOLE   33,333 0 0
EUCRATES BIOMEDICAL ACQU COR SHS G3141W106 976 99,999 SH   SOLE   99,999 0 0
EUROPEAN BIOTECH ACQUTN CORP *W EXP 03/06/202 G3167F128 60 100,000 SH   SOLE   100,000 0 0
EUROPEAN BIOTECH ACQUTN CORP CLASS A ORD SHS G3167F102 2,907 300,000 SH   SOLE   300,000 0 0
EYEPOINT PHARMACEUTICALS INC COM NEW 30233G209 30,841 2,519,700 SH   SOLE   2,519,700 0 0
FINSERV ACQUISITION CORP II *W EXP 02/17/202 31809Y111 169 273,149 SH   SOLE   273,149 0 0
FRAZIER LIFESCIENCES ACQU CO *W EXP 11/30/202 G3710A113 17 29,166 SH   SOLE   29,166 0 0
FRAZIER LIFESCIENCES ACQU CO CL A SHS G3710A105 853 87,498 SH   SOLE   87,498 0 0
FULCRUM THERAPEUTICS INC COM 359616109 42,024 2,375,571 SH   SOLE   2,375,571 0 0
GEMINI THERAPEUTICS INC COM 36870G105 6,903 2,372,267 SH   SOLE   2,372,267 0 0
GFL ENVIRONMENTAL INC SUB VTG SHS 36168Q104 175,133 4,627,040 SH   SOLE   4,627,040 0 0
GRAB HOLDINGS LIMITED CLASS A ORD G4124C109 14,260 2,000,000 SH   SOLE   2,000,000 0 0
HERON THERAPEUTICS INC COM 427746102 22,700 2,486,340 SH   SOLE   2,486,340 0 0
HILTON WORLDWIDE HLDGS INC COM 43300A203 93,441 599,022 SH   SOLE   599,022 0 0
IMMUNEERING CORP CLASS A COM 45254E107 3,234 200,000 SH   SOLE   200,000 0 0
INFLARX NV COM N44821101 15,637 3,285,000 SH   SOLE   3,285,000 0 0
INOZYME PHARMA INC COM 45790W108 6,910 1,013,216 SH   SOLE   1,013,216 0 0
INSMED INC COM PAR $.01 457669307 29,461 1,081,532 SH   SOLE   1,081,532 0 0
INTRA-CELLULAR THERAPIES INC COM 46116X101 65,527 1,251,946 SH   SOLE   1,251,946 0 0
IQVIA HLDGS INC COM 46266C105 157,931 559,760 SH   SOLE   559,760 0 0
KALVISTA PHARMACEUTICALS INC COM 483497103 23,104 1,746,300 SH   SOLE   1,746,300 0 0
KBR INC COM 48242W106 32,644 685,500 SH   SOLE   685,500 0 0
KEZAR LIFE SCIENCES INC COM 49372L100 23,574 1,409,956 SH   SOLE   1,409,956 0 0
KURA ONCOLOGY INC COM 50127T109 50,014 3,572,419 SH   SOLE   3,572,419 0 0
LAUDER ESTEE COS INC CL A 518439104 166,353 449,360 SH   SOLE   449,360 0 0
MARINUS PHARMACEUTICALS INC COM NEW 56854Q200 31,349 2,638,775 SH   SOLE   2,638,775 0 0
MARQETA INC CLASS A COM 57142B104 25,195 1,467,368 SH   SOLE   1,467,368 0 0
MARRIOTT INTL INC NEW CL A 571903202 81,569 493,640 SH   SOLE   493,640 0 0
MASTERCARD INCORPORATED CL A 57636Q104 89,927 250,270 SH   SOLE   250,270 0 0
MEIRAGTX HLDGS PLC COM G59665102 821 34,600 SH   SOLE   34,600 0 0
MEREO BIOPHARMA GROUP PLC ADS 589492107 14,627 9,142,067 SH   SOLE   9,142,067 0 0
MICROSOFT CORP COM 594918104 290,917 865,000 SH   SOLE   865,000 0 0
MILESTONE PHARMACEUTICALS IN COM 59935V107 5,576 851,291 SH   SOLE   851,291 0 0
MIRATI THERAPEUTICS INC COM 60468T105 59,085 402,789 SH   SOLE   402,789 0 0
MOLECULAR PARTNERS AG ADS 60853G106 7,672 400,000 SH   SOLE   400,000 0 0
MONSTER BEVERAGE CORP NEW COM 61174X109 109,841 1,143,700 SH   SOLE   1,143,700 0 0
NATERA INC COM 632307104 59,411 636,160 SH   SOLE   636,160 0 0
NUVALENT INC COM 670703107 3,808 200,000 SH   SOLE   200,000 0 0
OMEGA ALPHA SPAC CL A G6749V107 2,931 300,000 SH   SOLE   300,000 0 0
OPENDOOR TECHNOLOGIES INC COM 683712103 90,129 6,168,996 SH   SOLE   6,168,996 0 0
OPY ACQUISITION CORP I UNIT 09/22/2026 671005205 2,000 200,000 SH   SOLE   200,000 0 0
ORIC PHARMACEUTICALS INC COM 68622P109 6,478 440,696 SH   SOLE   440,696 0 0
OTIS WORLDWIDE CORP COM 68902V107 216,332 2,484,580 SH   SOLE   2,484,580 0 0
OTONOMY INC COM 68906L105 5,570 2,678,115 SH   SOLE   2,678,115 0 0
PHARVARIS N V COM N69605108 11,908 827,540 SH   SOLE   827,540 0 0
POINT BIOPHARMA GLOBAL INC COM 730541109 14,968 2,672,863 SH   SOLE   2,672,863 0 0
QUANTA SVCS INC COM 74762E102 133,351 1,163,015 SH   SOLE   1,163,015 0 0
RESEARCH ALLIANCE CORP II COM CL A 760873109 4,885 500,000 SH   SOLE   500,000 0 0
RH COM 74967X103 133,942 249,920 SH   SOLE   249,920 0 0
RIVIAN AUTOMOTIVE INC COM CL A 76954A103 52,657 507,830 SH   SOLE   507,830 0 0
ROIVANT SCIENCES LTD SHS G76279101 6,870 681,528 SH   SOLE   681,528 0 0
ROYALTY PHARMA PLC SHS CLASS A G7709Q104 78,396 1,967,273 SH   SOLE   1,967,273 0 0
SIO GENE THERAPIES INC COMMON 829399104 7,629 5,914,000 SH   SOLE   5,914,000 0 0
SOLID BIOSCIENCES INC COM 83422E105 11,003 6,287,193 SH   SOLE   6,287,193 0 0
SORRENTO THERAPEUTICS INC COM NEW 83587F202 492 105,744 SH   SOLE   105,744 0 0
SUTRO BIOPHARMA INC COM 869367102 36,274 2,437,795 SH   SOLE   2,437,795 0 0
TAPESTRY INC COM 876030107 184,627 4,547,460 SH   SOLE   4,547,460 0 0
TE CONNECTIVITY LTD SHS H84989104 61,732 382,623 SH   SOLE   382,623 0 0
TERNS PHARMACEUTICALS INC COM 880881107 8,758 1,238,800 SH   SOLE   1,238,800 0 0
THERMO FISHER SCIENTIFIC INC COM 883556102 180,468 270,470 SH   SOLE   270,470 0 0
TURMERIC ACQUISITION CORP *W EXP 10/08/202 G9127T124 45 66,666 SH   SOLE   66,666 0 0
TURMERIC ACQUISITION CORP CL A G9127T108 1,964 200,000 SH   SOLE   200,000 0 0
ULTRAGENYX PHARMACEUTICAL IN COM 90400D108 40,804 485,242 SH   SOLE   485,242 0 0
UNION PAC CORP COM 907818108 203,564 808,020 SH   SOLE   808,020 0 0
UNITEDHEALTH GROUP INC COM 91324P102 229,373 456,790 SH   SOLE   456,790 0 0
WARBY PARKER INC CL A COM 93403J106 34,147 733,402 SH   SOLE   733,402 0 0
XENON PHARMACEUTICALS INC COM 98420N105 21,618 692,000 SH   SOLE   692,000 0 0